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المؤلفون: Béatrice Turcq, Elisabeth Losdyck, Lorraine Springuel, Pascale Saussoy, Laurent Knoops, Francois-Xavier Mahon, Jean-Christophe Renauld
المساهمون: UCL - SSS/DDUV/GECE - Génétique cellulaire, UCL - SSS/DDUV/MEXP - Médecine expérimentale, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de biologie hématologique, UCL - (SLuc) Service d'hématologie, Centre National de la Recherche Scientifique (CNRS)
المصدر: Cellular and Molecular Life Sciences, Vol. 73, no. 24, p. 4739-4748 (2016)
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2016, 73 (24), pp.4739-4748. ⟨10.1007/s00018-016-2310-2⟩مصطلحات موضوعية: 0301 basic medicine, Genome instability, MESH: Oncogenes, DNA mismatch repair, Tyrosine kinase inhibitor, medicine.disease_cause, Tyrosine-kinase inhibitor, MESH: Down-Regulation, Mice, 0302 clinical medicine, MESH: DNA Methylation, RNA interference, MESH: RNA, Small Interfering, MESH: Janus Kinases, MESH: Protein Kinase Inhibitors, MESH: Animals, RNA, Small Interfering, Promoter Regions, Genetic, Oncogenic mutations, Mutation, Gene Expression Regulation, Leukemic, MESH: MutL Protein Homolog 1, MLH1, Myeloid leukemia, MESH: Drug Resistance, Neoplasm, 3. Good health, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, MESH: Gene Expression Regulation, Leukemic, Molecular Medicine, Intercellular Signaling Peptides and Proteins, MutL Protein Homolog 1, Tyrosine kinase, medicine.drug_class, Down-Regulation, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, Cell Line, 03 medical and health sciences, Cellular and Molecular Neuroscience, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, MESH: Promoter Regions, Genetic, medicine, Animals, Humans, Point Mutation, MESH: Intercellular Signaling Peptides and Proteins, Molecular Biology, Protein Kinase Inhibitors, MESH: Mice, Janus Kinases, MESH: Point Mutation, Pharmacology, MESH: Humans, Point mutation, Janus kinase (JAK), MESH: Clone Cells, Cell Biology, Oncogenes, DNA Methylation, MESH: Gene Knockdown Techniques, Clone Cells, MESH: Cell Line, 030104 developmental biology, MESH: Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Drug Resistance, Neoplasm, Drug resistance, Cancer research, Ectopic expression
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المؤلفون: Jean-Christophe Renauld, Elisabetta Flex, Sandrine Degryse, Jan Cools, Laurent Knoops, Tekla Hornakova, Marco Tartaglia, Elisabeth Losdyck, Stefan N. Constantinescu, Olga Gielen, Lorraine Springuel
المساهمون: UCL - (SLuc) Service d'hématologie, UCL - SSS/DDUV - Institut de Duve
المصدر: Journal of Biological Chemistry, Vol. 290, no. 48, p. 29022-29034 (2015)
مصطلحات موضوعية: Mutation, Missense, Tyrosine-protein kinase (tyrosine kinase), Biology, Signal transduction, Biochemistry, Mice, hemic and lymphatic diseases, Cell Line, Tumor, CD135, Animals, Humans, Receptors, Cytokine, Receptor, Molecular Biology, Protein Kinase Inhibitors, Oncogene, Common gamma chain, Mice, Inbred BALB C, Leukemia, Janus kinase 3, Janus kinase (JAK), Janus Kinase 3, Cell Biology, Janus Kinase 1, Janus Kinase 2, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Molecular biology, Neoplasm Proteins, Amino Acid Substitution, JAK inhibitor, Interleukin-21 receptor, Cancer research, Cytokine receptor, Tyrosine kinase, Signal Transduction
وصف الملف: Print-Electronic
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1deb3d95fd0dfca2ff6d4dc508b94953
https://hdl.handle.net/2078.1/166226 -
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المؤلفون: Stefan N. Constantinescu, Fanny Lambert, Emilie Leroy, Tekla Hornakova, Marco Tartaglia, Jean-Christophe Renauld, Elisabeth Losdyck, Lorraine Springuel, Elisabetta Flex, Laurent Knoops
المساهمون: UCL - SSS/DDUV - Institut de Duve, UCL - (SLuc) Service d'hématologie
المصدر: Blood, Vol. 124, no. 26, p. 3924-3931 (2014)
مصطلحات موضوعية: Immunology, Mutant, Mutation, Missense, Biology, medicine.disease_cause, Biochemistry, Cell Line, Mice, Adenosine Triphosphate, Nitriles, medicine, Animals, Humans, Point Mutation, Protein Kinase Inhibitors, Cell Proliferation, Janus Kinases, Mutation, Kinase, Janus kinase 3, Point mutation, Janus Kinase 3, Janus Kinase 1, Cell Biology, Hematology, Molecular biology, Protein Structure, Tertiary, Cell Transformation, Neoplastic, HEK293 Cells, Pyrimidines, Drug Resistance, Neoplasm, STAT protein, Pyrazoles, Signal transduction, Janus kinase, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7b0933515f13970bafa823c05f4edf
https://hdl.handle.net/2078.1/155937