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1
المؤلفون: Elizabeth Ann Gleason, L. Nathan Tumey, Steven M. Murphy, George Mbella Ekema, Bruce Sherf, Robert W. Mays, Joel Danzig, Jianping Song, John J. Harrington, Marc Palmer, Doug Hanniford, Gary Pawlowski, Michael J. Robarge, Chris Doucette, Margaret Loftus, Karen Hunady, Youssef L. Bennani, Alain Stricker-Krongrad, Kurt R. Brunden
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:3287-3290
مصطلحات موضوعية: Indoles, Receptors, Prostaglandin, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Chemical synthesis, Thromboxane A2, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Receptors, Immunologic, Molecular Biology, Prostaglandin D2 receptor, Indole test, Sulfonamides, Esterification, Chemistry, Organic Chemistry, Antagonist, In vitro, Molecular Medicine, Prostaglandin D2, Ramatroban, medicine.drug
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2
المؤلفون: John J. Harrington, Chris Doucette, Karen Hunady, Doug Hanniford, Margaret Loftus, Varga Norbert, L. Nathan Tumey, Daniel P. Silver, Elizabeth Ann Gleason, David C. Bom, Jianping Song, Joel Danzig, Marc Palmer, Steven M. Murphy, Michael J. Robarge, Gary Pawlowski, Youssef L. Bennani, George Mbella Ekema, Bruce Sherf, Robert W. Mays, Alain Stricker-Krongrad, Kurt R. Brunden
المصدر: Bioorganic & Medicinal Chemistry Letters. 15:1749-1753
مصطلحات موضوعية: Isostere, Receptors, Prostaglandin, Clinical Biochemistry, Carbazoles, Molecular Conformation, Pharmaceutical Science, Prostaglandin, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Isomerism, Drug Discovery, medicine, Anti-Asthmatic Agents, Receptors, Immunologic, Receptor, Molecular Biology, Sulfonamides, Molecular Structure, Organic Chemistry, Antagonist, Chemotaxis, Eosinophil, medicine.anatomical_structure, Models, Chemical, chemistry, Molecular Medicine, Ramatroban, Prostaglandin D2, medicine.drug
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3
المؤلفون: Elizabeth Ann Gleason, Lars Karlsson, Hui Cai, Damara Gebauer, James P. Edwards, Yin Gu, Siquan Sun, Michael K. Ameriks, Jian Zhu, Robin L. Thurmond, Steven Nguyen
المصدر: Bioorganicmedicinal chemistry letters. 19(21)
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Pyrazole, Biochemistry, Cell Line, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Piperidines, Morpholine, Drug Discovery, Potency, Animals, Humans, Protease Inhibitors, Molecular Biology, IC50, Cathepsin S, chemistry.chemical_classification, Bicyclic molecule, Organic Chemistry, Cathepsins, Enzyme, chemistry, Drug Design, Molecular Medicine, Pyrazoles, Pharmacophore
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4
المؤلفون: Steven M. Murphy, Bruce Sherf, Tom Dent, Daniel P. Silver, Andrew Bailey, L. Nathan Tumey, Jianmin Wang, Youssef L. Bennani, Elizabeth Ann Gleason, David C. Bom, Bayard Huck, Christina Leventhal, Sherry Boozer, John J. Harrington, Stephen Rundlett, Kurt R. Brunden
المصدر: Bioorganicmedicinal chemistry letters. 15(2)
مصطلحات موضوعية: Xeroderma pigmentosum, DNA repair, DNA damage, Flap Endonucleases, Clinical Biochemistry, Flap structure-specific endonuclease 1, Pharmaceutical Science, Biochemistry, Endonuclease, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Temozolomide, Humans, Urea, Enzyme Inhibitors, Molecular Biology, Xeroderma Pigmentosum, biology, Organic Chemistry, Base excision repair, medicine.disease, Methyl Methanesulfonate, Methyl methanesulfonate, Dacarbazine, chemistry, Urinary Bladder Neoplasms, biology.protein, Molecular Medicine, Nucleotide excision repair, DNA Damage
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5
المؤلفون: Jianmin Wang, John J. Harrington, Daniel P. Silver, Bayard Huck, Kurt R. Brunden, Christina Leventhal, Bruce Sherf, L. Nathan Tumey, Tom Dent, Steven M. Murphy, Elizabeth Ann Gleason, Andrew Bailey, Sherry Boozer, Stephen Rundlett, Youssef L. Bennani
المصدر: Bioorganicmedicinal chemistry letters. 14(19)
مصطلحات موضوعية: chemistry.chemical_classification, biology, DNA damage, DNA repair, Flap Endonucleases, Organic Chemistry, Clinical Biochemistry, Flap structure-specific endonuclease 1, Pharmaceutical Science, Base excision repair, Biochemistry, Endonuclease, chemistry.chemical_compound, Butyrates, Structure-Activity Relationship, Enzyme, chemistry, Drug Discovery, biology.protein, Molecular Medicine, Flap endonuclease, Enzyme Inhibitors, Molecular Biology, DNA