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1
المؤلفون: Walter G. Smith, Suzanne H Kim, Doreen Villani-Price, Matthew W Mahoney, Nayereh S Ghoreishi-Haack, Helen Y. Chen, Thomas D. Penning, Stella Siu-Tzyy Yu, James W. Malecha, Leslie J Askonas, Chi-Dean Liang, Elizabeth I Harding, E.Yvonne Pyla, Maureen K Highkin, James K. Gierse, Julie M Miyashiro, Mark A Russell, James F Kachur, Chen Barbara B
المصدر: Journal of Medicinal Chemistry. 45:3482-3490
مصطلحات موضوعية: Epoxide Hydrolases, chemistry.chemical_classification, biology, Stereochemistry, Administration, Oral, Leukotriene A4, Chemical synthesis, Proinflammatory cytokine, Leukotriene-A4 hydrolase, Mice, Structure-Activity Relationship, Enzyme, chemistry, Enzyme inhibitor, In vivo, Drug Discovery, Hydrolase, beta-Alanine, biology.protein, Animals, Humans, Molecular Medicine, Structure–activity relationship, Enzyme Inhibitors
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2
المؤلفون: Thomas D. Penning, Nizal S. Chandrakumar, Barbara B. Chen, Helen Y. Chen, Bipin N. Desai, Stevan W. Djuric, Stephen H. Docter, Alan F. Gasiecki, Richard A. Haack, Julie M. Miyashiro, Mark A. Russell, Stella S. Yu, David G. Corley, Richard C. Durley, Brian F. Kilpatrick, Barry L. Parnas, Leslie J. Askonas, James K. Gierse, Elizabeth I. Harding, Maureen K. Highkin, James F. Kachur, Suzanne H. Kim, Gwen G. Krivi, Doreen Villani-Price, E. Yvonne Pyla, Walter G. Smith, Nayereh S. Ghoreishi-Haack
المصدر: Journal of Medicinal Chemistry. 43:721-735
مصطلحات موضوعية: Male, Pyrrolidines, Tertiary amine, Administration, Oral, In Vitro Techniques, Pharmacology, Leukotriene B4, Leukotriene-A4 hydrolase, Mice, Structure-Activity Relationship, Drug Discovery, Hydrolase, Animals, Humans, Structure–activity relationship, Enzyme Inhibitors, Epoxide Hydrolases, chemistry.chemical_classification, biology, In vitro, Enzyme, Biochemistry, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Ex vivo
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3
المؤلفون: Doreen Villani-Price, Suzanne H Kim, Walter G. Smith, Leslie J Askonas, Elizabeth I Harding, Maureen K Highkin, Thomas D. Penning, Alan F. Gasiecki, Nayereh S Ghoreishi-Haack, Nizal S Chandrakumar, E.Yvonne Pyla, Bipin N Desai, James F Kachur, Mark A Russell, Stevan W Djuric, James W. Malecha, James K. Gierse, Julie M Miyashiro
المصدر: Bioorganic & Medicinal Chemistry Letters. 13:1137-1139
مصطلحات موضوعية: Imidazopyridine, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Purine analogue, In Vitro Techniques, Biochemistry, Chemical synthesis, Leukotriene-A4 hydrolase, Mice, Structure-Activity Relationship, Heterocyclic Compounds, Drug Discovery, Animals, Humans, Structure–activity relationship, Enzyme Inhibitors, Purine metabolism, Molecular Biology, Epoxide Hydrolases, biology, Chemistry, Organic Chemistry, Recombinant Proteins, stomatognathic diseases, Purines, Enzyme inhibitor, biology.protein, Molecular Medicine, Indicators and Reagents, Ex vivo
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4
المؤلفون: Maureen K Highkin, Leslie J Askonas, Doreen Villani-Price, Chi-Dean Liang, Bipin N Desai, Thomas D. Penning, James F Kachur, Elizabeth I Harding, Nayereh S Ghoreishi-Haack, Mark A Russell, Julie M Miyashiro, Walter G. Smith, E.Yvonne Pyla, Nizal S Chandrakumar, Stevan W Djuric, Suzanne H Kim, James K. Gierse, Alan F. Gasiecki
المصدر: Bioorganicmedicinal chemistry letters. 12(23)
مصطلحات موضوعية: Pyrrolidines, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, Biochemistry, Chemical synthesis, Pyrrolidine, Leukotriene-A4 hydrolase, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Piperidines, In vivo, Drug Discovery, Hydrolase, Structure–activity relationship, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Epoxide Hydrolases, biology, Chemistry, Organic Chemistry, stomatognathic diseases, Enzyme inhibitor, biology.protein, beta-Alanine, Molecular Medicine, Ex vivo
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5
المؤلفون: Ernest G. Jaworski, Elizabeth I. Harding, Judith Arlene Diaz-Collier, David C. Tiemeier, Roger C. Wiegand, Court Saunders, Dilip M. Shah, Thomas J. Mozer
المصدر: Plant Molecular Biology. 7:235-243
مصطلحات موضوعية: Messenger RNA, Expression vector, biology, Oligonucleotide, Plant Science, General Medicine, Molecular biology, Primer extension, chemistry.chemical_compound, Glutathione S-transferase, chemistry, Transcription (biology), Complementary DNA, Genetics, biology.protein, Agronomy and Crop Science, DNA
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6
المؤلفون: Dilip M. Shah, Gwen G. Krivi, Elizabeth I. Harding, Roger C. Wiegand, Cathy M. Hironaka, David C. Tiemeier
المصدر: Plant molecular biology. 6(4)
مصطلحات موضوعية: Genetics, Untranslated region, Nucleic acid sequence, Plant Science, General Medicine, Biology, Molecular biology, Exon, Glutathione S-transferase, Complementary DNA, biology.protein, Coding region, Agronomy and Crop Science, Peptide sequence, Gene