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1
المؤلفون: James Atherton, Shaila Kulkarni, Janean Hanson, Abdul E. Mutlib, Seva E. Kostrubsky, Bo Feng, Amit S. Kalgutkar, Ellen Urda, Raylene Kubik, Rouchelle J. Mireles, Stephen C. Strom
المصدر: Toxicological Sciences. 90:451-459
مصطلحات موضوعية: medicine.medical_specialty, medicine.drug_class, Pharmacology, Toxicology, Piperazines, Buspirone, Bile Acids and Salts, Rats, Sprague-Dawley, chemistry.chemical_compound, Internal medicine, medicine, Animals, Humans, Cells, Cultured, Bile acid, Bile Canaliculi, Trazodone, Biological Transport, Glutathione, Triazoles, Rats, medicine.anatomical_structure, Endocrinology, chemistry, Hepatocyte, Toxicity, Hepatocytes, Microsomes, Liver, Microsome, Antidepressive Agents, Second-Generation, Nefazodone, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc898e6352cacf42fe3e0ef989425f0
https://doi.org/10.1093/toxsci/kfj095 -
2
المؤلفون: Hongbo Cai, Jacqueline F. Sinclair, Stephen C. Strom, Vsevolod E. Kostrubsky, James Burliegh, Janean Hanson, Jasminder Sahi, Ellen Urda, Kelly Rose, Philip Zocharski
المصدر: Toxicological Sciences. 76:220-228
مصطلحات موضوعية: Taurocholic Acid, medicine.medical_specialty, Time Factors, medicine.drug_class, Drug Evaluation, Preclinical, Thiazines, Biology, Toxicology, digestive system, Bile Acids and Salts, Rats, Sprague-Dawley, chemistry.chemical_compound, Cholestasis, In vivo, Internal medicine, Cyclosporin a, Glyburide, medicine, Animals, Humans, Troleandomycin, Cells, Cultured, Bile acid, Biological Transport, Drug Synergism, medicine.disease, Taurocholic acid, Culture Media, Rats, Endocrinology, medicine.anatomical_structure, Liver, chemistry, Hepatocyte, Injections, Intravenous, Hepatocytes, Macrolides, Efflux, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f28a4be05a1923e4f7819d91bb2beaa
https://doi.org/10.1093/toxsci/kfg217 -
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المؤلفون: Devin Franklin Welty, Ellen Urda, Brian R. Krause, Donald G. Robertson, Michael J. Graziano, Gary D. Pilcher, Grushenka H. I. Wolfgang
المصدر: Biochemical Pharmacology. 49:799-808
مصطلحات موضوعية: Male, medicine.medical_specialty, Very low-density lipoprotein, Metabolite, Guinea Pigs, Sterol O-acyltransferase, Cmax, Biochemistry, chemistry.chemical_compound, Dogs, Cytochrome P-450 Enzyme System, Species Specificity, Pharmacokinetics, Internal medicine, medicine, Animals, Hypolipidemic Agents, Pharmacology, biology, Chemistry, Cytochrome P450, Rats, Macaca fascicularis, Cholesterol, Endocrinology, Enzyme inhibitor, Enzyme Induction, Microsomes, Liver, biology.protein, Microsome, Female, Carbamates, Sterol O-Acyltransferase
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المصدر: Toxicological Sciences. 28:51-58
مصطلحات موضوعية: Male, medicine.medical_specialty, Guanine, Cmax, Purine nucleoside phosphorylase, Motor Activity, Urinalysis, Biology, Weight Gain, Toxicology, Blood Urea Nitrogen, Excretion, Glycogen phosphorylase, chemistry.chemical_compound, Adjuvants, Immunologic, Oral administration, Internal medicine, medicine, Animals, Lymphocyte Count, Enzyme Inhibitors, Rats, Wistar, Sex Characteristics, Creatinine, Dehydration, Organ Size, Rats, Kidney Tubules, Endocrinology, Purine-Nucleoside Phosphorylase, chemistry, Toxicity, Urea, Female
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a46dfe208dca7c141f3034268cfd78
https://doi.org/10.1093/toxsci/28.1.51 -
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المؤلفون: Donna B. Stolz, Ellen Urda, Sheryl G. Wood, Yuan H. Wen, Jacqueline F. Sinclair, Shaila Kulkarni, Seva E. Kostrubsky, Abdul E. Mutlib, Stephen C. Strom
المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 87(1)
مصطلحات موضوعية: UGT1A6, Phenytoin, Glucuronidation, Pharmacology, Toxicology, Glucuronides, medicine, Humans, Drug Interactions, Glucuronosyltransferase, Cells, Cultured, Acetaminophen, Chemistry, digestive, oral, and skin physiology, Glutathione, medicine.anatomical_structure, Liver, Hepatocyte, Phenobarbital, Toxicity, Microsome, Hepatocytes, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e0679083120eb296a53daf3e6f061f
https://pubmed.ncbi.nlm.nih.gov/15933229 -
6Effects of bergamottin on human and monkey drug-metabolizing enzymes in primary cultured hepatocytes
المؤلفون: Stephen C. Strom, Vsevolod E. Kostrubsky, Yuan Hua Wen, Ellen Urda, Hongbo Cai, Xianxian Zheng, Shaila Kulkarni, Kelly Rose, Jacqueline F. Sinclair, Jasminder Sahi
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 30(9)
مصطلحات موضوعية: CYP2B6, CYP3A, Glucuronidation, Pharmaceutical Science, Pharmacology, Biology, chemistry.chemical_compound, Furanocoumarin, Cytochrome P-450 Enzyme System, Cytochrome P-450 CYP1A2, Furocoumarins, medicine, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP3A, Humans, Glucuronosyltransferase, Cells, Cultured, Dose-Response Relationship, Drug, CYP1A2, Cytochrome P450, Oxidoreductases, N-Demethylating, Bergamottin, Cytochrome P-450 CYP2B6, medicine.anatomical_structure, chemistry, Biochemistry, Hepatocyte, biology.protein, Hepatocytes, Aryl Hydrocarbon Hydroxylases, Citrus paradisi
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606d93d3f0c50607e6b1b2598ed509d3
https://pubmed.ncbi.nlm.nih.gov/12167562 -
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المصدر: Archives of toxicology. 72(6)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Aging, Cellular respiration, Health, Toxicology and Mutagenesis, Mitochondria, Liver, Biology, Mitochondrion, Toxicology, DNA, Mitochondrial, Dogs, Species Specificity, In vivo, Internal medicine, Respiration, medicine, Animals, Humans, Respiratory system, Rats, Wistar, Aged, Endoplasmic reticulum, General Medicine, Haplorhini, Middle Aged, Rats, Endocrinology, Liver, Tacrine, Toxicity, Female, medicine.drug
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المصدر: Current eye research. 16(12)
مصطلحات موضوعية: Male, medicine.medical_specialty, Interim Sacrifice, Time Factors, Atorvastatin, Coenzyme A, Reductase, Pharmacology, Beagle, Cataract, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Dogs, Cataracts, Internal medicine, Lens, Crystalline, medicine, Animals, Pyrroles, Dosing, biology, business.industry, Anticholesteremic Agents, medicine.disease, Sensory Systems, Ophthalmology, Endocrinology, Cholesterol, chemistry, Heptanoic Acids, HMG-CoA reductase, biology.protein, lipids (amino acids, peptides, and proteins), Female, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, medicine.drug
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المصدر: Purine and Pyrimidine Metabolism in Man VIII ISBN: 9781461361053
مصطلحات موضوعية: Deoxyguanosine triphosphate, biology, Purine nucleoside phosphorylase, Molecular biology, In vitro, chemistry.chemical_compound, Orally active, Adenosine deaminase, chemistry, Biochemistry, Repeated doses, biology.protein, Purine metabolism, Intracellular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cda0e4867be442bd4be4f4b666f78283
https://doi.org/10.1007/978-1-4615-2584-4_38 -
10
المؤلفون: Brian R. Krause, R. F. Bousley, R. L. Stanfield, Donald G. Robertson, K.A. Kieft, Roger S. Newton, Ellen Urda
المصدر: Pharmacological research. 29(4)
مصطلحات موضوعية: Male, medicine.medical_specialty, Butanols, Lipoproteins, Guinea Pigs, Rats, Sprague-Dawley, chemistry.chemical_compound, In vivo, Internal medicine, polycyclic compounds, medicine, Hydroxybenzoates, Gemfibrozil, Animals, Lovastatin, Hypolipidemic Agents, Pharmacology, biology, Cholesterol, nutritional and metabolic diseases, Biological activity, Hydroxymethylglutaryl-CoA reductase, Lipids, Rats, Sterols, Endocrinology, chemistry, Enzyme inhibitor, HMG-CoA reductase, biology.protein, lipids (amino acids, peptides, and proteins), medicine.drug