المؤلفون: Sternberg, C, Gruber, W, Eberl, M, Tesanovic, S, Stadler, M, Elmer, DP, Schlederer, M, Grund, S, Roos, S, Wolff, F, Kaur, S, Mangelberger, D, Lehrach, H, Hache, H, Wierling, C, Laimer, J, Lackner, P, Wiederstein, M, Kasper, M, Risch, A, Petzelbauer, P, Moriggl, R, Kenner, L, Aberger, F

المصدر: International journal of cancer. 143(11):2943-2954

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:139662194

المؤلفون: Luciano M; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Cancer Cluster Salzburg, Salzburg, 5020, Austria., Sieberer H; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Krenn PW; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Dang HH; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Vetter J; Bioinformatics Research Group, University of Applied Sciences Upper Austria, Hagenberg Campus, Hagenberg, 4232, Austria., Neuper T; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Amend D; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Blöchl C; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria., Weichenberger CX; Institute for Biomedicine, Eurac Research, Bolzano, 39100, Italy., Eglseer A; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Unger MS; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Andosch A; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria., Steiner P; Institute of Pharmacology, Medical Faculty, Johannes Kepler University Linz, Linz, 4020, Austria., Neureiter D; Cancer Cluster Salzburg, Salzburg, 5020, Austria.; Institute of Pathology, Paracelsus Medical University (PMU), University Hospital Salzburg (SALK), Salzburg, 5020, Austria., Bauer R; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria., Hummer L; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria., Tesanovic S; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Cancer Cluster Salzburg, Salzburg, 5020, Austria., Binder S; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria., Elmer DP; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria., Strandt H; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria., Schaller S; Bioinformatics Research Group, University of Applied Sciences Upper Austria, Hagenberg Campus, Hagenberg, 4232, Austria., Strunk D; Cancer Cluster Salzburg, Salzburg, 5020, Austria.; Cell Therapy Institute, Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University (PMU), Salzburg, 5020, Austria., Pleyer L; Cancer Cluster Salzburg, Salzburg, 5020, Austria.; Salzburg Cancer Research Institute (SCRI)-LIMCR, Salzburg, 5020, Austria.; 3rd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Oncologic Center, Paracelsus Medical University (PMU), University Hospital Salzburg (SALK), Salzburg, 5020, Austria., Greil R; Cancer Cluster Salzburg, Salzburg, 5020, Austria.; Salzburg Cancer Research Institute (SCRI)-LIMCR, Salzburg, 5020, Austria.; 3rd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Oncologic Center, Paracelsus Medical University (PMU), University Hospital Salzburg (SALK), Salzburg, 5020, Austria., Winkler S; Bioinformatics Research Group, University of Applied Sciences Upper Austria, Hagenberg Campus, Hagenberg, 4232, Austria., Hartmann TN; Department of Medicine I, Medical Center, Faculty of Medicine, University of Freiburg, 79106, Freiburg, Germany., Schmidt-Arras D; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Huber CG; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Cancer Cluster Salzburg, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Aberger F; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria.; Cancer Cluster Salzburg, Salzburg, 5020, Austria.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria., Horejs-Hoeck J; Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Hellbrunner Strasse 34, Salzburg, 5020, Austria. jutta.horejs-hoeck@plus.ac.at.; Cancer Cluster Salzburg, Salzburg, 5020, Austria. jutta.horejs-hoeck@plus.ac.at.; Center for Tumor Biology and Immunology, Paris-Lodron University Salzburg, Salzburg, 5020, Austria. jutta.horejs-hoeck@plus.ac.at.

المصدر: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 02; Vol. 22 (1), pp. 424. Date of Electronic Publication: 2024 Sep 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/pathology , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/genetics , Apoptosis*/genetics , Eukaryotic Initiation Factor-2*/metabolism , Eukaryotic Initiation Factor-2*/genetics , eIF-2 Kinase*/metabolism , eIF-2 Kinase*/genetics, Humans ; Animals ; Mice ; Signal Transduction ; Cell Line, Tumor ; Disease Progression ; Inflammasomes/metabolism

المؤلفون: Peer E; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria., Aichberger SK; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria., Vilotic F; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria., Gruber W; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria., Parigger T; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria.; Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Salzburg Cancer Research Institute, Cancer Cluster Salzburg, IIIrd Medical Department, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria., Grund-Gröschke S; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria., Elmer DP; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria., Rathje F; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria., Ramspacher A; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria.; Research Program for Receptor Biochemistry and Tumor Metabolism, Department of Pediatrics, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria., Zaja M; 4SC AG, Planegg-Martinsried, 82152 Planegg, Germany., Michel S; 4SC AG, Planegg-Martinsried, 82152 Planegg, Germany., Hamm S; 4SC AG, Planegg-Martinsried, 82152 Planegg, Germany., Aberger F; Department of Bioscience, Cancer Cluster Salzburg, Paris-Lodron University Salzburg, 5020 Salzburg, Austria.

المصدر: Cancers [Cancers (Basel)] 2021 Aug 23; Vol. 13 (16). Date of Electronic Publication: 2021 Aug 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Bauer J; Department of Human Genetics, University Medical Center Goettingen, Goettingen, Germany., Cuvelier N; Department of Human Genetics, University Medical Center Goettingen, Goettingen, Germany., Ragab N; Department of Human Genetics, University Medical Center Goettingen, Goettingen, Germany., Simon-Keller K; Institute of Pathology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany., Nitzki F; Department of Human Genetics, University Medical Center Goettingen, Goettingen, Germany., Geyer N; Department of Human Genetics, University Medical Center Goettingen, Goettingen, Germany., Botermann DS; Department of Human Genetics, University Medical Center Goettingen, Goettingen, Germany., Elmer DP; Department of Biosciences, Paris-Lodron University of Salzburg, Cancer Cluster Salzburg, Salzburg, Austria., Rosenberger A; Department of Genetic Epidemiology, University Medical Center Goettingen, Goettingen, Germany., Rando TA; Paul F. Glenn Center for the Biology of Aging and Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA., Biressi S; Paul F. Glenn Center for the Biology of Aging and Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.; Neurology Service, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.; Department of Cellular, Computational and Integrative Biology (CIBIO) and Dulbecco Telethon Institute, University of Trento, Povo-Trento, Italy., Fagin JA; Memorial Sloan Kettering Cancer Center, New York, NY, USA., Saur D; Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar der TUM, Muenchen, Germany., Dullin C; Institute for Diagnostic and Interventional Radiology, University Medical Center Goettingen, Goettingen, Germany., Schildhaus HU; Institute of Pathology, University Medical Center Essen, Essen, Germany., Schulz-Schaeffer W; Department of Neuropathology, Saarland University Medical Center, Homburg, Germany., Aberger F; Department of Biosciences, Paris-Lodron University of Salzburg, Cancer Cluster Salzburg, Salzburg, Austria., Uhmann A; Department of Human Genetics, University Medical Center Goettingen, Goettingen, Germany., Hahn H; Department of Human Genetics, University Medical Center Goettingen, Goettingen, Germany. hhahn@gwdg.de.

المصدر: Oncogene [Oncogene] 2021 Aug; Vol. 40 (31), pp. 4955-4966. Date of Electronic Publication: 2021 Jun 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Disease Susceptibility* , Genes, ras*, Neoplasms/*etiology , Neoplasms/*metabolism , Protein Isoforms/*genetics, Age Factors ; Animals ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Disease Models, Animal ; Disease Progression ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; MAP Kinase Signaling System ; Mice ; Mice, Knockout ; Mutation ; Neoplasms/pathology ; Neoplastic Stem Cells ; Oncogenes ; Patched-1 Receptor/genetics ; Zinc Finger Protein GLI1/genetics ; Zinc Finger Protein GLI1/metabolism

المؤلفون: Tripolt S; Institute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, Vienna, Austria., Neubauer HA; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria., Knab VM; Institute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, Vienna, Austria., Elmer DP; Department of Biosciences, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, Austria., Aberger F; Department of Biosciences, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, Austria., Moriggl R; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria., Fux DA; Institute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, Vienna, Austria. Electronic address: sabrina_tripolt@gmx.net.

المصدر: Neoplasia (New York, N.Y.) [Neoplasia] 2021 Feb; Vol. 23 (2), pp. 270-279. Date of Electronic Publication: 2021 Jan 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5586 (Electronic) Linking ISSN: 14765586 NLM ISO Abbreviation: Neoplasia Subsets: MEDLINE

مواضيع طبية MeSH: Analgesics, Opioid/*pharmacology , Breast Neoplasms/*metabolism , Breast Neoplasms/*pathology , Receptors, Opioid, delta/*metabolism , STAT3 Transcription Factor/*metabolism, Animals ; Biomarkers ; Breast Neoplasms/etiology ; Cell Line, Tumor ; Disease Models, Animal ; Disease Susceptibility ; Female ; Gene Expression ; Humans ; Immunohistochemistry ; Mice ; Mice, Transgenic ; Neoplasm Metastasis ; Oncogene Proteins/metabolism ; Receptors, Opioid, delta/agonists ; Receptors, Opioid, delta/genetics

المؤلفون: Gruber W; Department of Molecular Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria., Peer E; Department of Molecular Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria., Elmer DP; Department of Molecular Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria., Sternberg C; Department of Molecular Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria., Tesanovic S; Department of Molecular Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria., Del Burgo P; Department of Molecular Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria., Coni S; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy., Canettieri G; Department of Molecular Medicine, Sapienza University of Rome, Rome, 00161, Italy., Neureiter D; Institute of Pathology, Cancer Cluster Salzburg, Paracelsus Medical University, Salzburger Landeskliniken (SALK), Salzburg, 5020, Austria., Bartz R; 4SC AG, Planegg-Martinsried, 82152, Germany., Kohlhof H; 4SC AG, Planegg-Martinsried, 82152, Germany.; Immunic AG, Planegg-Martinsried, 82152, Germany., Vitt D; 4SC AG, Planegg-Martinsried, 82152, Germany.; Immunic AG, Planegg-Martinsried, 82152, Germany., Aberger F; Department of Molecular Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria.

المصدر: International journal of cancer [Int J Cancer] 2018 Mar 01; Vol. 142 (5), pp. 968-975. Date of Electronic Publication: 2017 Nov 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm*, Benzamides/*pharmacology , Carcinoma, Basal Cell/*drug therapy , Hedgehog Proteins/*antagonists & inhibitors , Histone Deacetylases/*chemistry , Smoothened Receptor/*antagonists & inhibitors , Zinc Finger Protein GLI1/*antagonists & inhibitors, Animals ; Apoptosis ; Carcinogenesis/drug effects ; Carcinogenesis/metabolism ; Carcinogenesis/pathology ; Carcinoma, Basal Cell/metabolism ; Carcinoma, Basal Cell/pathology ; Cell Proliferation ; Hedgehog Proteins/metabolism ; Histone Deacetylases/metabolism ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Signal Transduction ; Smoothened Receptor/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays ; Zinc Finger Protein GLI1/metabolism

المؤلفون: Wessler S; Division of Microbiology, Cancer Cluster Salzburg, Department of Molecular Biology, Paris-Lodron University of Salzburg, Billroth Strasse 11, A-5020, Salzburg, Austria. Silja.Wessler@sbg.ac.at., Krisch LM; Division of Microbiology, Cancer Cluster Salzburg, Department of Molecular Biology, Paris-Lodron University of Salzburg, Billroth Strasse 11, A-5020, Salzburg, Austria., Elmer DP; Division of Molecular Tumor Biology, Cancer Cluster Salzburg, Department of Molecular Biology, Paris-Lodron University of Salzburg, Hellbrunner Strasse 34, A-5020, Salzburg, Austria., Aberger F; Division of Molecular Tumor Biology, Cancer Cluster Salzburg, Department of Molecular Biology, Paris-Lodron University of Salzburg, Hellbrunner Strasse 34, A-5020, Salzburg, Austria. Fritz.Aberger@sbg.ac.at.

المصدر: Cell communication and signaling : CCS [Cell Commun Signal] 2017 Apr 20; Vol. 15 (1), pp. 15. Date of Electronic Publication: 2017 Apr 20.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Hedgehog Proteins/*metabolism , Helicobacter pylori/*physiology , Stomach Neoplasms/*microbiology , Stomach Neoplasms/*pathology , Zinc Finger Protein GLI1/*metabolism, Animals ; Humans ; Inflammation/microbiology ; Inflammation/pathology

المؤلفون: Gruber W; Cancer Cluster Salzburg, Department of Molecular Biology, University of Salzburg, Salzburg, Austria., Hutzinger M; Cancer Cluster Salzburg, Department of Molecular Biology, University of Salzburg, Salzburg, Austria., Elmer DP; Cancer Cluster Salzburg, Department of Molecular Biology, University of Salzburg, Salzburg, Austria., Parigger T; Cancer Cluster Salzburg, Department of Molecular Biology, University of Salzburg, Salzburg, Austria., Sternberg C; Cancer Cluster Salzburg, Department of Molecular Biology, University of Salzburg, Salzburg, Austria., Cegielkowski L; Cancer Cluster Salzburg, Department of Molecular Biology, University of Salzburg, Salzburg, Austria., Zaja M; 4SC Discovery GmbH, Planegg-Martinsried, Germany., Leban J; Department of Pediatrics, Medical University of Vienna, Vienna, Austria., Michel S; 4SC Discovery GmbH, Planegg-Martinsried, Germany., Hamm S; 4SC Discovery GmbH, Planegg-Martinsried, Germany., Vitt D; 4SC Discovery GmbH, Planegg-Martinsried, Germany.; 4SC AG, Planegg-Martinsried, Germany., Aberger F; Cancer Cluster Salzburg, Department of Molecular Biology, University of Salzburg, Salzburg, Austria.

المصدر: Oncotarget [Oncotarget] 2016 Feb 09; Vol. 7 (6), pp. 7134-48.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm*, Carcinoma, Basal Cell/*pathology , Hedgehog Proteins/*metabolism , Pancreatic Neoplasms/*pathology , Protein Serine-Threonine Kinases/*metabolism , Protein-Tyrosine Kinases/*metabolism , Smoothened Receptor/*metabolism , Zinc Finger Protein GLI1/*metabolism, Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Blotting, Western ; Carcinoma, Basal Cell/drug therapy ; Carcinoma, Basal Cell/genetics ; Carcinoma, Basal Cell/metabolism ; Cell Proliferation/drug effects ; Cells, Cultured ; Forkhead Transcription Factors/physiology ; Hedgehog Proteins/antagonists & inhibitors ; Hedgehog Proteins/genetics ; Humans ; Mice ; Mice, Nude ; NIH 3T3 Cells ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/metabolism ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Protein Serine-Threonine Kinases/genetics ; Protein-Tyrosine Kinases/antagonists & inhibitors ; Protein-Tyrosine Kinases/genetics ; RNA, Messenger/genetics ; RNA, Small Interfering/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Skin Neoplasms/drug therapy ; Skin Neoplasms/genetics ; Skin Neoplasms/metabolism ; Skin Neoplasms/pathology ; Smoothened Receptor/antagonists & inhibitors ; Smoothened Receptor/genetics ; Xenograft Model Antitumor Assays ; Zinc Finger Protein GLI1/antagonists & inhibitors ; Zinc Finger Protein GLI1/genetics ; Dyrk Kinases

المؤلفون: Shinde DN; The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors., Elmer DP, Calabrese P, Boulanger J, Arnheim N, Tiemann-Boege I

المصدر: Human molecular genetics [Hum Mol Genet] 2013 Oct 15; Vol. 22 (20), pp. 4117-26. Date of Electronic Publication: 2013 Jun 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: Paternal Age* , Selection, Genetic*, Achondroplasia/*genetics , Receptor, Fibroblast Growth Factor, Type 3/*genetics, Aged, 80 and over ; Aging ; Computer Simulation ; Germ-Line Mutation ; Humans ; Male ; Models, Genetic ; Polymorphism, Single Nucleotide ; Spermatogonia/cytology ; Spermatogonia/metabolism ; Testis/metabolism ; Testis/pathology