يعرض 1 - 10 نتائج من 96 نتيجة بحث عن '"Ely Benaim"', وقت الاستعلام: 1.16s تنقيح النتائج
  1. 1
    دورية أكاديمية
    RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer

    المؤلفون: John J. Tentler, Julie Lang, Anna Capasso, Deog Joong Kim, Ely Benaim, Young B. Lee, Andrew Eisen, Stacey M. Bagby, Sarah J. Hartman, Betelehem W. Yacob, Brian Gittleman, Todd M. Pitts, Roberta Pelanda, S. Gail Eckhardt, Jennifer R. Diamond

    المصدر: BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)

    مصطلحات موضوعية: RX-5902, Triple-negative breast cancer, p68, β-Catenin, PD-1 inhibitor, Immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

    وصف الملف: electronic resource

    Relation: http://link.springer.com/article/10.1186/s12885-020-07500-1; https://doaj.org/toc/1471-2407

    URL الوصول: https://doaj.org/article/1dcda43bbcb945d6ae883320daa5d648

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  2. 2
    Data from First-in-Class Phosphorylated-p68 Inhibitor RX-5902 Inhibits β-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer

    المؤلفون: Jennifer R. Diamond, John J. Tentler, S. Gail Eckhardt, Todd M. Pitts, Jihye Kim, Aik Choon Tan, Sarah J. Hartman, Brian Gittleman, Ely Benaim, Young B. Lee, Christina George, Deog Joong Kim, Julie G. Frank, Anastasia Ionkina, Betelehem W. Yacob, Naomi Currimjee, Kyrie L. Dailey, Stacey M. Bagby, Anna Capasso

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3570a4b7073fb17fadee2a9d11204b79
    https://doi.org/10.1158/1535-7163.c.6538611.v1

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  3. 3
    Supplementary Figure S1 from First-in-Class Phosphorylated-p68 Inhibitor RX-5902 Inhibits β-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer

    المؤلفون: Jennifer R. Diamond, John J. Tentler, S. Gail Eckhardt, Todd M. Pitts, Jihye Kim, Aik Choon Tan, Sarah J. Hartman, Brian Gittleman, Ely Benaim, Young B. Lee, Christina George, Deog Joong Kim, Julie G. Frank, Anastasia Ionkina, Betelehem W. Yacob, Naomi Currimjee, Kyrie L. Dailey, Stacey M. Bagby, Anna Capasso

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5d27faa7abc00285d7541d06c04edd
    https://doi.org/10.1158/1535-7163.22507179.v1

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  4. 4
    A multicenter phase 1/2 study investigating the safety, pharmacokinetics, pharmacodynamics and efficacy of a small molecule antimetabolite, RX-3117, plus nab-paclitaxel in pancreatic adenocarcinoma

    المؤلفون: Nafisa Burhani, Hani M. Babiker, Emad Elquza, Andrea J. Bullock, Ely Benaim, Allyson J. Ocean, Lee G. Hicks, Peter J. Schlegel, Christine B. Peterson, Daruka Mahadevan, Mitesh J. Borad, Callie Heaton

    المصدر: Investigational New Drugs. 40:81-90

    مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, business.industry, Nausea, medicine.drug_class, medicine.disease, Gastroenterology, Antimetabolite, Gemcitabine, Oncology, Tolerability, Pharmacokinetics, Pancreatic cancer, Pharmacodynamics, Internal medicine, Medicine, Pharmacology (medical), medicine.symptom, Adverse effect, business, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8841b5475e5beb9575ab758350b71ace
    https://doi.org/10.1007/s10637-021-01164-9

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  5. 5
    A multicenter phase 1/2 study investigating the safety, pharmacokinetics, pharmacodynamics and efficacy of a small molecule antimetabolite, RX-3117, plus nab-paclitaxel in pancreatic adenocarcinoma

    المؤلفون: Hani, Babiker, Peter J, Schlegel, Lee G, Hicks, Andrea J, Bullock, Nafisa, Burhani, Daruka, Mahadevan, Emad, Elquza, Mitesh J, Borad, Ely, Benaim, Christine, Peterson, Callie, Heaton, Allyson J, Ocean

    المصدر: Investigational new drugs. 40(1)

    مصطلحات موضوعية: Aged, 80 and over, Male, Dose-Response Relationship, Drug, Maximum Tolerated Dose, Paclitaxel, Metabolic Clearance Rate, Cytidine, Adenocarcinoma, Middle Aged, Drug Administration Schedule, Pancreatic Neoplasms, Albumins, Area Under Curve, Antineoplastic Combined Chemotherapy Protocols, Humans, Female, Aged, Half-Life

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::651202fed5992602007b5c919335cd35
    https://pubmed.ncbi.nlm.nih.gov/34417914

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  6. 6
    RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment

    المؤلفون: Richard J. Honeywell, Young Bok Lee, Godefridus J. Peters, Christine B. Peterson, Julie Poore, Dzjemma Sarkisjan, Callie Heaton, Ely Benaim, Elisa Giovannetti, Btissame El Hassouni, Beatrice Balboni, Deog Joong Kim

    المساهمون: VU University medical center, Medical oncology laboratory, Medical oncology, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer biology and immunology

    المصدر: Expert Opinion on Investigational Drugs, 28(4), 311-322. Taylor and Francis Ltd.
    Balboni, B, el Hassouni, B, Honeywell, R J, Sarkisjan, D, Giovannetti, E, Poore, J, Heaton, C, Peterson, C, Benaim, E, Lee, Y B, Kim, D J & Peters, G J 2019, ' RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment ', Expert Opinion on Investigational Drugs, vol. 28, no. 4, pp. 311-322 . https://doi.org/10.1080/13543784.2019.1583742

    مصطلحات موضوعية: 0301 basic medicine, Antimetabolites, Antineoplastic, medicine.drug_class, Administration, Oral, Biological Availability, Cytidine, Deoxycytidine, Antimetabolite, DNA methyltransferase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Neoplasms, medicine, Humans, Pharmacology (medical), Pharmacology, Nucleoside analogue, Chemistry, Patient Selection, General Medicine, Gemcitabine, Small molecule, Cancer treatment, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Cytosine, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de49d19ad4125048d6f79e1a3e85708a
    https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063098464&origin=inward

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  7. 7
    RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer

    المؤلفون: Young Bok Lee, John J. Tentler, Ely Benaim, Brian Gittleman, Julie E. Lang, Stacey M. Bagby, S. Gail Eckhardt, Jennifer R. Diamond, Anna Capasso, Betelehem W. Yacob, Deog Joong Kim, Sarah J. Hartman, Todd M. Pitts, Andrew Eisen, Roberta Pelanda

    المصدر: BMC Cancer
    BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)

    مصطلحات موضوعية: 0301 basic medicine, Granzyme B production, Cancer Research, Myeloid, medicine.medical_treatment, Apoptosis, Triple Negative Breast Neoplasms, Piperazines, Mice, 0302 clinical medicine, Tumor Cells, Cultured, Tumor Microenvironment, Immune Checkpoint Inhibitors, beta Catenin, Mice, Inbred BALB C, RX-5902, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, p68, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Drug Therapy, Combination, Female, Immunotherapy, Humanized mouse models, Nivolumab, Research Article, β-Catenin, Mice, Nude, lcsh:RC254-282, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, Immune system, Triple-negative breast cancer, Quinoxalines, Genetics, medicine, Animals, Humans, Cell Proliferation, Tumor microenvironment, business.industry, Tumor-infiltrating lymphocytes, Xenograft Model Antitumor Assays, Immune checkpoint, PD-1 inhibitor, 030104 developmental biology, Cancer research, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60907b1468b02ce996f4be0c49304637
    https://doi.org/10.1186/s12885-020-07500-1

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  8. 8
    A phase I safety study of topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia

    المؤلفون: Brian Berman, Mario E. Lacouture, Shobha Ravipaty, Eric M. Grund, Ely Benaim, Shari Goldfarb, Rangaprasad Sarangarajan, Khampaseuth Thapa, Nikunj Tanna, Niven R. Narain, Hedy Dion, Joaquin J. Jimenez, Elder Granger, Nathaniel DiTommaso, Shen Luan

    المصدر: Breast Cancer Res Treat

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_specialty, Nausea, medicine.medical_treatment, Antineoplastic Agents, Breast Neoplasms, Article, 03 medical and health sciences, 0302 clinical medicine, Calcitriol, Internal medicine, Medicine, Topical Calcitriol, Humans, Adverse effect, Chemotherapy, Taxane, business.industry, Alopecia, Regimen, 030104 developmental biology, Oncology, Tolerability, 030220 oncology & carcinogenesis, Vomiting, Quality of Life, Female, medicine.symptom, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ead4c9c23a9b7bdee8a46605bf9e2e
    https://pubmed.ncbi.nlm.nih.gov/33206291

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  9. 9
    Additional file 2 of RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer

    المؤلفون: Tentler, John J., Lang, Julie, Capasso, Anna, Deog Joong Kim, Ely Benaim, Lee, Young B., Eisen, Andrew, Bagby, Stacey M., Hartman, Sarah J., Betelehem W. Yacob, Gittleman, Brian, Pitts, Todd M., Pelanda, Roberta, S. Gail Eckhardt, Diamond, Jennifer R.

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0057354a40dfe4c934f273d345e8eb44

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  10. 10
    Additional file 1 of RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer

    المؤلفون: Tentler, John J., Lang, Julie, Capasso, Anna, Deog Joong Kim, Ely Benaim, Lee, Young B., Eisen, Andrew, Bagby, Stacey M., Hartman, Sarah J., Betelehem W. Yacob, Gittleman, Brian, Pitts, Todd M., Pelanda, Roberta, S. Gail Eckhardt, Diamond, Jennifer R.

    مصطلحات موضوعية: hemic and immune systems, chemical and pharmacologic phenomena

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba569170111e9c07b4229822382a133

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