المؤلفون: Kverneland AH; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; National Center of Cancer Immune Therapy, Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark., Østergaard O; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Emdal KB; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Svane IM; National Center of Cancer Immune Therapy, Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark., Olsen JV; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

المصدر: Proteomics [Proteomics] 2023 Apr; Vol. 23 (7-8), pp. e2200039. Date of Electronic Publication: 2022 Nov 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101092707 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-9861 (Electronic) Linking ISSN: 16159853 NLM ISO Abbreviation: Proteomics Subsets: MEDLINE

مواضيع طبية MeSH: Proteome*/analysis , Extracellular Vesicles*/metabolism, Humans ; Proteomics/methods ; Mass Spectrometry/methods ; Ultracentrifugation

المؤلفون: Emdal KB; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Palacio-Escat N; Heidelberg University, Faculty of Medicine and Heidelberg University Hospital, Institute for Computational Biomedicine, BioQuant-Zentrum, Heidelberg, Germany; Heidelberg University, Faculty of Biosciences, Heidelberg, Germany; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine, Aachen, Germany., Wigerup C; Acrivon Therapeutics Inc., Watertown, MA, USA., Eguchi A; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nilsson H; Acrivon Therapeutics Inc., Watertown, MA, USA., Bekker-Jensen DB; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rönnstrand L; Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, Lund, Sweden., Kazi JU; Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, Lund, Sweden., Puissant A; INSERM UMR 944, IRSL, St Louis Hospital, Paris, France., Itzykson R; INSERM UMR 944, IRSL, St Louis Hospital, Paris, France., Saez-Rodriguez J; Heidelberg University, Faculty of Medicine and Heidelberg University Hospital, Institute for Computational Biomedicine, BioQuant-Zentrum, Heidelberg, Germany; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine, Aachen, Germany. Electronic address: pub.saez@uni-heidelberg.de., Masson K; Acrivon Therapeutics Inc., Watertown, MA, USA. Electronic address: kmasson@acrivon.com., Blume-Jensen P; Acrivon Therapeutics Inc., Watertown, MA, USA. Electronic address: pblumejensen@acrivon.com., Olsen JV; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: jesper.olsen@cpr.ku.dk.

المصدر: Cell reports [Cell Rep] 2022 Aug 09; Vol. 40 (6), pp. 111177.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/metabolism , Tumor Suppressor Protein p53*/metabolism, Apoptosis ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Humans ; Hydrazines ; Proteome/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Triazoles

المؤلفون: Dugourd A; Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg University, Heidelberg, Germany.; Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), RWTH Aachen University, Aachen, Germany.; Faculty of Medicine, Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.; Division of Nephrology and Clinical Immunology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany., Kuppe C; Faculty of Medicine, Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.; Division of Nephrology and Clinical Immunology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, The Netherlands., Sciacovelli M; MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, UK., Gjerga E; Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg University, Heidelberg, Germany.; Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), RWTH Aachen University, Aachen, Germany., Gabor A; Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg University, Heidelberg, Germany., Emdal KB; Faculty of Health and Medical Sciences, Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Vieira V; Centre of Biological Engineering, University of Minho - Campus de Gualtar, Braga, Portugal., Bekker-Jensen DB; Faculty of Health and Medical Sciences, Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Kranz J; Faculty of Medicine, Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.; Department of Urology and Pediatric Urology, St. Antonius Hospital Eschweiler, Academic Teaching Hospital of RWTH Aachen, Eschweiler, Germany.; Department of Urology and Kidney Transplantation, Martin Luther University, Halle (Saale), Germany., Bindels EMJ; Department of Hematology, Erasmus MC, Rotterdam, The Netherlands., Costa ASH; MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, UK., Sousa A; Institute for Research and Innovation in Health (i3s), Porto, Portugal.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Beltrao P; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Rocha M; Centre of Biological Engineering, University of Minho - Campus de Gualtar, Braga, Portugal., Olsen JV; Faculty of Health and Medical Sciences, Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Frezza C; MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, UK., Kramann R; Faculty of Medicine, Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.; Division of Nephrology and Clinical Immunology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, The Netherlands., Saez-Rodriguez J; Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg University, Heidelberg, Germany.; Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), RWTH Aachen University, Aachen, Germany.; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory, Heidelberg University, Heidelberg, Germany.

المصدر: Molecular systems biology [Mol Syst Biol] 2021 Jan; Vol. 17 (1), pp. e9730.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: EMBO Press Country of Publication: England NLM ID: 101235389 Publication Model: Print Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Regulatory Networks*, Carcinoma, Renal Cell/*genetics , Computational Biology/*methods , Kidney Neoplasms/*genetics, Carcinoma, Renal Cell/metabolism ; Case-Control Studies ; Gene Expression Profiling ; Humans ; Kidney Neoplasms/metabolism ; Metabolomics ; Phosphoproteins

المؤلفون: Emdal KB; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lundby A; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

المصدر: Molecular & cellular oncology [Mol Cell Oncol] 2019 Dec 06; Vol. 7 (1), pp. 1692643. Date of Electronic Publication: 2019 Dec 06 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101642411 Publication Model: eCollection Cited Medium: Print ISSN: 2372-3556 (Print) Linking ISSN: 23723556 NLM ISO Abbreviation: Mol Cell Oncol Subsets: PubMed not MEDLINE

المؤلفون: Hamilton WB; The Novo Nordisk Foundation Center for Stem Cell Biology, Copenhagen, Denmark., Mosesson Y; Weizmann Institute of Science, Rehovot, Israel., Monteiro RS; The Novo Nordisk Foundation Center for Stem Cell Biology, Copenhagen, Denmark., Emdal KB; The Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark., Knudsen TE; The Novo Nordisk Foundation Center for Stem Cell Biology, Copenhagen, Denmark., Francavilla C; The Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark.; Division of Molecular and Cellular Function, School of Biological Sciences, FBMH, The University of Manchester, Manchester, UK., Barkai N; Weizmann Institute of Science, Rehovot, Israel., Olsen JV; The Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark., Brickman JM; The Novo Nordisk Foundation Center for Stem Cell Biology, Copenhagen, Denmark. joshua.brickman@sund.ku.dk.

المصدر: Nature [Nature] 2019 Nov; Vol. 575 (7782), pp. 355-360. Date of Electronic Publication: 2019 Nov 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Cell Lineage*, Extracellular Signal-Regulated MAP Kinases/*metabolism , Mouse Embryonic Stem Cells/*cytology , Mouse Embryonic Stem Cells/*metabolism, Animals ; Extracellular Signal-Regulated MAP Kinases/genetics ; Mediator Complex/deficiency ; Mediator Complex/metabolism ; Mice ; Protein Binding ; Transcription, Genetic

المؤلفون: Lundby A; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: alicia.lundby@sund.ku.dk., Franciosa G; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Emdal KB; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Refsgaard JC; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Gnosa SP; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Bekker-Jensen DB; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Secher A; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark; Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark., Maurya SR; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Paul I; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Mendez BL; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Kelstrup CD; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Francavilla C; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Kveiborg M; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Montoya G; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Jensen LJ; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark., Olsen JV; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Faculty of Health and Medical Sciences, Blegdamsvej 3b, DK-2200 Copenhagen, Denmark. Electronic address: jesper.olsen@cpr.ku.dk.

المصدر: Cell [Cell] 2019 Oct 03; Vol. 179 (2), pp. 543-560.e26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Carcinogenesis/*genetics , ErbB Receptors/*genetics , Lung Neoplasms/*genetics , Lung Neoplasms/*metabolism , Phosphotyrosine/*metabolism, A549 Cells ; Animals ; Humans ; Mass Spectrometry/methods ; Mutation ; Phosphoproteins/metabolism ; Phosphorylation ; Proteomics ; Rats ; Rats, Sprague-Dawley ; Zebrafish

المؤلفون: Randall EC; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Emdal KB; Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main St, Cambridge, MA, 02142, USA., Laramy JK; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, 55455, USA., Kim M; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, 55455, USA., Roos A; Department of Cancer Biology, Mayo Clinic, 13400 E. Shea Blvd.MCCRB 03-055, Scottsdale, AZ, 85259, USA., Calligaris D; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Regan MS; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Gupta SK; Department of Radiation Oncology, Mayo Clinic, 200 First St SW, Rochester, MN, 55902, USA., Mladek AC; Department of Radiation Oncology, Mayo Clinic, 200 First St SW, Rochester, MN, 55902, USA., Carlson BL; Department of Radiation Oncology, Mayo Clinic, 200 First St SW, Rochester, MN, 55902, USA., Johnson AJ; Department of Immunology, Mayo Clinic, 200 First St SW, Rochester, MN, 55902, USA., Lu FK; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, 02138, USA.; Department of Biomedical Engineering, Binghamton University, State University of New York, Binghamton, NY, 13902, USA., Xie XS; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, 02138, USA., Joughin BA; Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main St, Cambridge, MA, 02142, USA., Reddy RJ; Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main St, Cambridge, MA, 02142, USA., Peng S; Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Abdelmoula WM; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Jackson PR; Mathematical NeuroOncology Lab, Department of Neurosurgery, Mayo Clinic, 5777 E. Mayo Blvd, Phoenix, AZ, 85054, USA., Kolluri A; Mathematical NeuroOncology Lab, Department of Neurosurgery, Mayo Clinic, 5777 E. Mayo Blvd, Phoenix, AZ, 85054, USA., Kellersberger KA; Bruker Daltonics, Billerica, MA, 01821, USA., Agar JN; Department of Chemistry and Chemical Biology, Northeastern University, 412 TF (140 The Fenway), Boston, MA, 02111, USA., Lauffenburger DA; Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main St, Cambridge, MA, 02142, USA., Swanson KR; Mathematical NeuroOncology Lab, Department of Neurosurgery, Mayo Clinic, 5777 E. Mayo Blvd, Phoenix, AZ, 85054, USA., Tran NL; Department of Cancer Biology, Mayo Clinic, 13400 E. Shea Blvd.MCCRB 03-055, Scottsdale, AZ, 85259, USA., Elmquist WF; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, 55455, USA., White FM; Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main St, Cambridge, MA, 02142, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, 200 First St SW, Rochester, MN, 55902, USA., Agar NYR; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. Nathalie_Agar@dfci.harvard.edu.; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. Nathalie_Agar@dfci.harvard.edu.; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02115, USA. Nathalie_Agar@dfci.harvard.edu.

المصدر: Nature communications [Nat Commun] 2018 Nov 21; Vol. 9 (1), pp. 4904. Date of Electronic Publication: 2018 Nov 21.

نوع المنشور: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacokinetics , Erlotinib Hydrochloride/*pharmacokinetics , Glioblastoma/*drug therapy, Animals ; Antineoplastic Agents/administration & dosage ; ErbB Receptors/antagonists & inhibitors ; Erlotinib Hydrochloride/administration & dosage ; Female ; Magnetic Resonance Imaging ; Mice, Nude ; Neoplasm Transplantation ; Protein-Tyrosine Kinases/metabolism ; Sequence Analysis, RNA ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

المؤلفون: Emdal KB; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.; Department of Biological Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA., Pedersen AK; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark., Bekker-Jensen DB; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark., Lundby A; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark., Claeys S; Center for Medical Genetics Ghent, Cancer Research Institute Ghent, De Pintelaan 185, 9000 Ghent, Belgium., De Preter K; Center for Medical Genetics Ghent, Cancer Research Institute Ghent, De Pintelaan 185, 9000 Ghent, Belgium., Speleman F; Center for Medical Genetics Ghent, Cancer Research Institute Ghent, De Pintelaan 185, 9000 Ghent, Belgium., Francavilla C; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark. chiara.francavilla@manchester.ac.uk jesper.olsen@cpr.ku.dk.; Division of Molecular and Cellular Functions, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK., Olsen JV; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark. chiara.francavilla@manchester.ac.uk jesper.olsen@cpr.ku.dk.

المصدر: Science signaling [Sci Signal] 2018 Nov 20; Vol. 11 (557). Date of Electronic Publication: 2018 Nov 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Anaplastic Lymphoma Kinase/*metabolism , Brain Neoplasms/*metabolism , Insulin Receptor Substrate Proteins/*metabolism , Neuroblastoma/*metabolism , Proteomics/*methods, Cell Line, Tumor ; Cell Survival ; Computational Biology ; Forkhead Box Protein O3/metabolism ; Humans ; Mass Spectrometry ; Peptides/chemistry ; Phosphorylation ; Proteome ; RNA Interference ; RNA, Small Interfering/metabolism ; Signal Transduction ; Transfection

المؤلفون: Liu H; Department of Pathology, and Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts., Murphy CJ; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York.; Meyer Cancer Center, Weill Cornell Medicine, New York, New York., Karreth FA; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Emdal KB; Department of Biological Engineering, Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts., White FM; Department of Biological Engineering, Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts., Elemento O; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York., Toker A; Department of Pathology, and Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.; Department of Pathology, and Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, and Ludwig Center at Harvard, Boston, Massachusetts., Wulf GM; Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts., Cantley LC; Meyer Cancer Center, Weill Cornell Medicine, New York, New York. lcantley@med.cornell.edu.

المصدر: Cancer discovery [Cancer Discov] 2018 Mar; Vol. 8 (3), pp. 354-369. Date of Electronic Publication: 2017 Dec 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Mammary Neoplasms, Experimental/*genetics , Triple Negative Breast Neoplasms/*genetics, Animals ; BRCA1 Protein ; Female ; Gene Fusion ; Humans ; MAP Kinase Signaling System/genetics ; Mammary Neoplasms, Experimental/drug therapy ; Mice, Mutant Strains ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-raf/genetics ; Proto-Oncogene Proteins c-raf/metabolism ; Receptor, Fibroblast Growth Factor, Type 2/genetics ; Receptor, Fibroblast Growth Factor, Type 2/metabolism ; Sequence Analysis, RNA ; Triple Negative Breast Neoplasms/drug therapy ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Proteins/genetics ; Exome Sequencing

المؤلفون: Emdal KB; Department of Biological Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts., Dittmann A; Department of Biological Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts., Reddy RJ; Department of Biological Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts., Lescarbeau RS; Department of Biological Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts., Moores SL; Oncology, Janssen Research and Development, LLC, Spring House, Pennsylvania., Laquerre S; Oncology, Janssen Research and Development, LLC, Spring House, Pennsylvania., White FM; Department of Biological Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts. fwhite@mit.edu.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2017 Nov; Vol. 16 (11), pp. 2572-2585. Date of Electronic Publication: 2017 Aug 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung/*drug therapy , ErbB Receptors/*genetics , Piperazines/*administration & dosage , Protein Kinase Inhibitors/*administration & dosage , Proto-Oncogene Proteins c-met/*genetics, Acrylamides ; Adaptor Proteins, Signal Transducing/genetics ; Aniline Compounds ; Animals ; Antibodies, Bispecific/administration & dosage ; Antibodies, Bispecific/adverse effects ; Benzodioxoles/administration & dosage ; Benzodioxoles/adverse effects ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm/genetics ; ErbB Receptors/antagonists & inhibitors ; Humans ; Mice ; Mutation ; Protein Kinase Inhibitors/immunology ; Proto-Oncogene Proteins c-met/antagonists & inhibitors ; Quinazolines/administration & dosage ; Quinazolines/adverse effects ; Src Homology 2 Domain-Containing, Transforming Protein 1/genetics ; Xenograft Model Antitumor Assays ; src-Family Kinases/genetics