المؤلفون: Pascart T; Service de Rhumatologie, Hôpital Saint-Philibert, Lille, France. Electronic address: pascart.tristan@ghicl.net., Wasik KA; Variant Bio, Seattle, WA, USA., Preda C; Department of Methodology and Biostatistics, Hôpital Saint-Philibert, Lille, France., Chune V; Department of Biology, Centre Hospitalier de Polynésie Française, Pape'ete, Tahiti, French Polynesia., Torterat J; Institut de la Statistique de Polynésie Française, Papeete, Tahiti, French Polynesia., Prud'homme N; Institut de la Statistique de Polynésie Française, Papeete, Tahiti, French Polynesia., Nassih M; Lille Catholic University and Research Department, Hôpital Saint-Philibert, Lille, France., Martin A; Lille Catholic University and Research Department, Hôpital Saint-Philibert, Lille, France., Le Masson J; Lille Catholic University and Research Department, Hôpital Saint-Philibert, Lille, France., Rodière V; Lille Catholic University and Research Department, Hôpital Saint-Philibert, Lille, France; Direction de la Santé de Polynésie Française, Papeete, Tahiti, French Polynesia., Frogier S; Lille Catholic University and Research Department, Hôpital Saint-Philibert, Lille, France; Direction de la Santé de Polynésie Française, Papeete, Tahiti, French Polynesia., Canova G; Lille Catholic University and Research Department, Hôpital Saint-Philibert, Lille, France; Direction de la Santé de Polynésie Française, Papeete, Tahiti, French Polynesia., Pescheux JP; Lille Catholic University and Research Department, Hôpital Saint-Philibert, Lille, France; Direction de la Santé de Polynésie Française, Papeete, Tahiti, French Polynesia., Shan Sei Fan C; Rheumatology Private Practice, Papeete, Tahiti, French Polynesia., Jauffret C; Service de Rhumatologie, Hôpital Saint-Philibert, Lille, France., Claeys P; Department of Biology, Centre Hospitalier de Polynésie Française, Pape'ete, Tahiti, French Polynesia., von Baeyer SL; Variant Bio, Seattle, WA, USA., Castel SE; Variant Bio, Seattle, WA, USA., Emde AK; Variant Bio, Seattle, WA, USA., Yerges-Armstrong L; Variant Bio, Seattle, WA, USA., Fox K; Global Health Program, Department of Anthropology and Indigenous Futures Institute, Division of Design and Innovation, University of California San Diego, San Diego, CA, USA; Native BioData Consortium, Eagle Butte, SD, USA., Leask M; Division of Clinical Rheumatology and Immunology, University of Alabama, Birmingham, AL, USA; Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand., Vitagliano JJ; Lille Catholic University and Research Department, Hôpital Saint-Philibert, Lille, France., Graf S; Department of Methodology and Biostatistics, Hôpital Saint-Philibert, Lille, France., Norberciak L; Department of Methodology and Biostatistics, Hôpital Saint-Philibert, Lille, France., Raynal J; Ministère de la Santé de Polynésie Française, Papeete, Tahiti, French Polynesia., Dalbeth N; Department of Medicine, University of Auckland, Auckland, New Zealand., Merriman T; Division of Clinical Rheumatology and Immunology, University of Alabama, Birmingham, AL, USA; Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand., Bardin T; National Institute of Health and Medical Research U1132, Université Paris-Cité, Hôpital Lariboisière, Paris, France., Oehler E; Department of Internal Medicine and Infectious Diseases, Centre Hospitalier de Polynésie Française, Pape'ete, Tahiti, French Polynesia.

المصدر: The Lancet. Global health [Lancet Glob Health] 2024 Apr; Vol. 12 (4), pp. e685-e696.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101613665 Publication Model: Print Cited Medium: Internet ISSN: 2214-109X (Electronic) Linking ISSN: 2214109X NLM ISO Abbreviation: Lancet Glob Health Subsets: MEDLINE

مواضيع طبية MeSH: Hyperuricemia*/epidemiology , Hyperuricemia*/genetics , Diabetes Mellitus, Type 2* , Gout*/epidemiology , Gout*/genetics, Adult ; Humans ; Male ; Female ; Uric Acid ; Cross-Sectional Studies ; Prospective Studies ; Polynesia/epidemiology ; HLA-B Antigens

المؤلفون: Paulson TG; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA. tpaulson@fredhutch.org., Galipeau PC; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA., Oman KM; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA., Sanchez CA; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA., Kuhner MK; Department of Genome Sciences, University of Washington, Seattle, WA, 98195-5065, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, 98195-5065, USA., Smith LP; Department of Genome Sciences, University of Washington, Seattle, WA, 98195-5065, USA., Hadi K; New York Genome Center (NYGC), New York, NY, 10013, USA., Shah M; New York Genome Center (NYGC), New York, NY, 10013, USA., Arora K; New York Genome Center (NYGC), New York, NY, 10013, USA., Shelton J; New York Genome Center (NYGC), New York, NY, 10013, USA., Johnson M; New York Genome Center (NYGC), New York, NY, 10013, USA., Corvelo A; New York Genome Center (NYGC), New York, NY, 10013, USA., Maley CC; Arizona Cancer Evolution Center, Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, AZ, 85281, USA., Yao X; New York Genome Center (NYGC), New York, NY, 10013, USA., Sanghvi R; New York Genome Center (NYGC), New York, NY, 10013, USA., Venturini E; New York Genome Center (NYGC), New York, NY, 10013, USA., Emde AK; Variant Bio, Brooklyn, NY, 11205, USA., Hubert B; New York Genome Center (NYGC), New York, NY, 10013, USA., Imielinski M; New York Genome Center (NYGC), New York, NY, 10013, USA.; Department of Pathology and Laboratory Medicine, Englander Institute for Precision Medicine, Institute for Computational Biomedicine and Meyer Cancer Center, Weill Cornell Medical College, New York, NY, 10065, USA., Robine N; New York Genome Center (NYGC), New York, NY, 10013, USA., Reid BJ; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, 98195-5065, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, 98195-5065, USA.; Department of Medicine, University of Washington, Seattle, WA, 98195, USA., Li X; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA. xili@fredhutch.org.

المصدر: Nature communications [Nat Commun] 2022 Apr 28; Vol. 13 (1), pp. 2300. Date of Electronic Publication: 2022 Apr 28.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma*/pathology , Barrett Esophagus*/genetics , Barrett Esophagus*/pathology , Esophageal Neoplasms*/pathology, Disease Progression ; Humans

SCR Disease Name: Adenocarcinoma Of Esophagus

المؤلفون: Symer DE; Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Akagi K; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Geiger HM; New York Genome Center, New York, New York 10013, USA., Song Y; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Li G; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Emde AK; New York Genome Center, New York, New York 10013, USA., Xiao W; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Jiang B; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Corvelo A; New York Genome Center, New York, New York 10013, USA., Toussaint NC; New York Genome Center, New York, New York 10013, USA., Li J; Division of Medical Oncology, Department of Internal Medicine, Ohio State University, Columbus, Ohio 43210, USA., Agrawal A; Department of Otolaryngology - Head and Neck Surgery, Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA., Ozer E; Department of Otolaryngology - Head and Neck Surgery, Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA., El-Naggar AK; Division of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Du Z; Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Shewale JB; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Stache-Crain B; Complete Genomics, San Jose, California 95134, USA., Zucker M; Department of Biomedical Informatics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA., Robine N; New York Genome Center, New York, New York 10013, USA., Coombes KR; Department of Biomedical Informatics, Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA., Gillison ML; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

المصدر: Genome research [Genome Res] 2022 Jan; Vol. 32 (1), pp. 55-70. Date of Electronic Publication: 2021 Dec 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9518021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-5469 (Electronic) Linking ISSN: 10889051 NLM ISO Abbreviation: Genome Res Subsets: MEDLINE

مواضيع طبية MeSH: Alphapapillomavirus*/metabolism , Oncogene Proteins, Viral*/genetics , Oropharyngeal Neoplasms*/genetics, Carcinogenesis ; Humans ; Papillomaviridae/genetics ; Papillomaviridae/metabolism ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism ; Virus Integration/genetics

المؤلفون: Emde AK; Variant Bio Inc., Seattle, WA, USA., Phipps-Green A; Department of Biochemistry, University of Otago, Dunedin, New Zealand., Cadzow M; Department of Biochemistry, University of Otago, Dunedin, New Zealand., Gallagher CS; Variant Bio Inc., Seattle, WA, USA., Major TJ; Department of Biochemistry, University of Otago, Dunedin, New Zealand., Merriman ME; Department of Biochemistry, University of Otago, Dunedin, New Zealand., Topless RK; Department of Biochemistry, University of Otago, Dunedin, New Zealand., Takei R; Department of Biochemistry, University of Otago, Dunedin, New Zealand.; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA., Dalbeth N; Department of Medicine, University of Auckland, Auckland, New Zealand., Murphy R; Department of Medicine, University of Auckland, Auckland, New Zealand., Stamp LK; University of Otago Christchurch, Christchurch, New Zealand., de Zoysa J; Department of Medicine, University of Auckland, Auckland, New Zealand., Wilcox PL; Department of Mathematics and Statistics, University of Otago, Dunedin, New Zealand., Fox K; Departments of Anthropology and Global Health, University of California, San Diego, CA, USA., Wasik KA; Variant Bio Inc., Seattle, WA, USA. kaja@variantbio.com., Merriman TR; Department of Biochemistry, University of Otago, Dunedin, New Zealand. tony.merriman@otago.ac.nz.; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA. tony.merriman@otago.ac.nz., Castel SE; Variant Bio Inc., Seattle, WA, USA. stephane@variantbio.com.

المصدر: BMC genomics [BMC Genomics] 2021 Nov 01; Vol. 22 (1), pp. 666. Date of Electronic Publication: 2021 Nov 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study* , Polymorphism, Single Nucleotide*, Genome ; Genome, Human ; Genomics ; Genotype ; Humans ; Whole Genome Sequencing

المؤلفون: Taliun D; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Harris DN; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Kessler MD; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Carlson J; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Szpiech ZA; Department of Biology, Pennsylvania State University, University Park, PA, USA.; Institute for Computational and Data Sciences, Pennsylvania State University, University Park, PA, USA., Torres R; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA., Taliun SAG; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Corvelo A; New York Genome Center, New York, NY, USA., Gogarten SM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Kang HM; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Pitsillides AN; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., LeFaive J; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Lee SB; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Tian X; Department of Biostatistics, University of Washington, Seattle, WA, USA., Browning BL; Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA, USA., Das S; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Emde AK; New York Genome Center, New York, NY, USA., Clarke WE; New York Genome Center, New York, NY, USA., Loesch DP; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Shetty AC; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Blackwell TW; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Smith AV; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Wong Q; Department of Biostatistics, University of Washington, Seattle, WA, USA., Liu X; USF Genomics, College of Public Health, University of South Florida, Tampa, FL, USA., Conomos MP; Department of Biostatistics, University of Washington, Seattle, WA, USA., Bobo DM; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Aguet F; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Albert C; Massachusetts General Hospital, Boston, MA, USA., Alonso A; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Ardlie KG; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Arking DE; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Aslibekyan S; University of Alabama, Birmingham, AL, USA., Auer PL; Zilber School of Public Health, University of Wisconsin Milwaukee, Milwaukee, WI, USA., Barnard J; Cleveland Clinic, Cleveland, OH, USA., Barr RG; Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Department of Epidemiology, Columbia University Medical Center, New York, NY, USA., Barwick L; The Emmes Corporation, Rockville, MD, USA., Becker LC; Johns Hopkins University, Baltimore, MD, USA., Beer RL; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Benjamin EJ; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.; Framingham Heart Study, Framingham, MA, USA., Bielak LF; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA., Blangero J; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Boehnke M; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Brody JA; Department of Medicine, University of Washington, Seattle, WA, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Burchard EG; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Cade BE; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Casella JF; Department of Pediatrics, Johns Hopkins University, Baltimore, MD, USA.; Division of Pediatric Hematology, Johns Hopkins University, Baltimore, MD, USA., Chalazan B; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA., Cho MH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Choi SH; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chung MK; Department of Cardiovascular Medicine, Heart & Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA., Clish CB; Metabolomics Platform, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Population Health Science, University of Mississippi Medical Center, Jackson, MS, USA., Curran JE; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Custer B; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA., Darbar D; Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Daya M; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., de Andrade M; Mayo Clinic, Rochester, MN, USA., DeMeo DL; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Dutcher SK; McDonnell Genome Institute, Washington University, St Louis, MO, USA.; Department of Genetics, Washington University, St Louis, MO, USA., Ellinor PT; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Emery LS; Department of Biostatistics, University of Washington, Seattle, WA, USA., Eng C; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Fatkin D; Molecular Cardiology Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.; Faculty of Medicine, University of New South Wales, Kensington, New South Wales, Australia.; Cardiology Department, St Vincent's Hospital, Darlinghurst, New South Wales, Australia., Fingerlin T; National Jewish Health, Center for Genes, Environment and Health, Denver, CO, USA., Forer L; Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Franceschini N; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Fuchsberger C; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria.; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Fullerton SM; Department of Bioethics & Humanities, University of Washington School of Medicine, Seattle, WA, USA., Germer S; New York Genome Center, New York, NY, USA., Gladwin MT; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.; Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Gottlieb DJ; VA Boston Healthcare System, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA., Hall ME; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., He J; Department of Epidemiology, Tulane University, New Orleans, LA, USA.; Tulane University Translational Science Institute, Tulane University, New Orleans, LA, USA., Heard-Costa NL; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Heckbert SR; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Johnsen JM; Department of Medicine, University of Washington, Seattle, WA, USA.; Bloodworks Northwest Research Institute, Seattle, WA, USA., Johnson AD; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Framingham, MA, USA., Kaplan R; Albert Einstein College of Medicine, New York, NY, USA., Kardia SLR; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA., Kelly T; Department of Epidemiology, Tulane University, New Orleans, LA, USA., Kelly S; Department of Epidemiology, Vitalant Research Institute, San Francisco, CA, USA.; Department of Pediatrics, UCSF Benioff Children's Hospital, Oakland, CA, USA.; Division of Pediatric Hematology, UCSF Benioff Children's Hospital, Oakland, CA, USA., Kenny EE; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kiel DP; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Klemmer R; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Konkle BA; Department of Medicine, University of Washington, Seattle, WA, USA.; Bloodworks Northwest Research Institute, Seattle, WA, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Köttgen A; Department of Epidemiology, Johns Hopkins University, Baltimore, MD, USA.; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany., Lange LA; Department of Medicine, University of Colorado at Denver, Aurora, CO, USA., Lasky-Su J; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Brigham and Women's Hospital, Boston, MA, USA., Levy D; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Framingham, MA, USA., Lin X; Biostatistics and Statistics, Harvard University, Boston, MA, USA., Lin KH; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Liu C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Garman L; Department of Genes and Human Disease, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Gerszten R; Beth Israel Deaconess Medical Center, Boston, MA, USA., Lubitz SA; Massachusetts General Hospital, Boston, MA, USA., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Mak ACY; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.; Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA., Manning AK; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA.; Metabolism Program, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mathias RA; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., McManus DD; Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA, USA., McGarvey ST; International Health Institute, Brown University, Providence, RI, USA.; Department of Epidemiology, Brown University, Providence, RI, USA.; Department of Anthropology, Brown University, Providence, RI, USA., Meigs JB; Division of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School, The Broad Institute of MIT and Harvard, Boston, MA, USA., Meyers DA; University of Arizona, Tucson, AZ, USA., Mikulla JL; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Minear MA; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Mitchell BD; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA., Mohanty S; Texas Cardiac Arrhythmia Institute, St David's Medical Center, Austin, TX, USA.; Department of Internal Medicine, Dell Medical School, Austin, TX, USA., Montasser ME; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Montgomery C; Department of Genes and Human Disease, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Murabito JM; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Natale A; Texas Cardiac Arrhythmia Institute, St David's Medical Center, Austin, TX, USA., Natarajan P; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Nelson SC; Department of Biostatistics, University of Washington, Seattle, WA, USA., North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., O'Connell JR; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Peyser PA; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA., Pleiness J; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Post WS; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Psaty BM; Department of Medicine, University of Washington, Seattle, WA, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Rao DC; Division of Biostatistics, Washington University in St Louis, St Louis, MO, USA., Redline S; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Roden D; Vanderbilt University Medical Center, Nashville, TN, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA., Ruczinski I; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Sarnowski C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Schoenherr S; Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Schwartz DA; University of Colorado at Denver, Denver, CO, USA., Seo JS; Precision Medicine Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.; Macrogen Inc, Seoul, Republic of Korea.; Gong Wu Genomic Medicine Institute, Seoul National University Bundang Hospital, Seongnam, Republic of Korea., Seshadri S; Framingham Heart Study, Framingham, MA, USA.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center at San Antonio, San Antonio, TX, USA., Sheehan VA; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, USA., Sheu WH; Taichung Veterans General Hospital Taiwan, Taichung City, Taiwan., Shoemaker MB; Vanderbilt University Medical Center, Nashville, TN, USA., Smith NL; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, WA, USA., Smith JA; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Sotoodehnia N; Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Stilp AM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Tang W; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA., Telen M; Duke University, Durham, NC, USA., Thornton TA; Department of Biostatistics, University of Washington, Seattle, WA, USA., Tracy RP; Department of Pathology & Laboratory Medicine, University of Vermont Larner College of Medicine, Burlington, VT, USA., Van Den Berg DJ; Center for Genetic Epidemiology, Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Vasan RS; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; Framingham Heart Study, Framingham, MA, USA., Viaud-Martinez KA; Illumina Laboratory Services, Illumina Inc, San Diego, CA, USA., Vrieze S; Department of Psychology, University of Minnesota, Minneapolis, MN, USA., Weeks DE; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Weir BS; Department of Biostatistics, University of Washington, Seattle, WA, USA., Weiss ST; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Brigham and Women's Hospital, Boston, MA, USA., Weng LC; Massachusetts General Hospital, Boston, MA, USA., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine-Cardiology, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Zhang Y; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.; Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Zhao X; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Arnett DK; Department of Epidemiology, University of Kentucky, Lexington, KY, USA., Ashley-Koch AE; Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA., Barnes KC; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Boerwinkle E; University of Texas Health Science Center at Houston, Houston, TX, USA.; Baylor College of Medicine Human Genome Sequencing Center, Houston, TX, USA., Gabriel S; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gibbs R; Baylor College of Medicine Human Genome Sequencing Center, Houston, TX, USA., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.; Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA., Silverman EK; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Qasba P; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Gan W; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Papanicolaou GJ; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Nickerson DA; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Northwest Genomics Center, Seattle, WA, USA.; Brotman Baty Institute, Seattle, WA, USA., Browning SR; Department of Biostatistics, University of Washington, Seattle, WA, USA., Zody MC; New York Genome Center, New York, NY, USA., Zöllner S; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA. adrienne@bu.edu.; Framingham Heart Study, Framingham, MA, USA. adrienne@bu.edu., Laurie CC; Department of Biostatistics, University of Washington, Seattle, WA, USA. cclaurie@uw.edu., Jaquish CE; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. jaquishc@nhlbi.nih.gov., Hernandez RD; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA. ryan.hernandez@mcgill.ca.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada. ryan.hernandez@mcgill.ca.; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA, USA. ryan.hernandez@mcgill.ca.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA. ryan.hernandez@mcgill.ca.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA. ryan.hernandez@mcgill.ca., O'Connor TD; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. timothydoconnor@gmail.com.; Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. timothydoconnor@gmail.com.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. timothydoconnor@gmail.com., Abecasis GR; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA. goncalo@umich.edu.

مؤلفون مشاركون: NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium

المصدر: Nature [Nature] 2021 Feb; Vol. 590 (7845), pp. 290-299. Date of Electronic Publication: 2021 Feb 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Genomics* , National Heart, Lung, and Blood Institute (U.S.)* , Precision Medicine*/standards, Genetic Variation/*genetics , Genome, Human/*genetics, Cytochrome P-450 CYP2D6/genetics ; Haplotypes/genetics ; Heterozygote ; Humans ; INDEL Mutation ; Loss of Function Mutation ; Mutagenesis ; Phenotype ; Polymorphism, Single Nucleotide ; Population Density ; Quality Control ; Sample Size ; United States ; Whole Genome Sequencing/standards

المؤلفون: Henssen AG; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Koche R; Cancer Biology & Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhuang J; Program in Bioinformatics and Integrative Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA., Jiang E; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Reed C; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Eisenberg A; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Still E; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., MacArthur IC; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rodríguez-Fos E; Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center (BSC-CNS), Barcelona, Spain., Gonzalez S; Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center (BSC-CNS), Barcelona, Spain., Puiggròs M; Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center (BSC-CNS), Barcelona, Spain., Blackford AN; The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK., Mason CE; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY, USA., de Stanchina E; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gönen M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Emde AK; New York Genome Center, New York, NY, USA., Shah M; New York Genome Center, New York, NY, USA., Arora K; New York Genome Center, New York, NY, USA., Reeves C; New York Genome Center, New York, NY, USA., Socci ND; Bioinformatics Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Perlman E; Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Antonescu CR; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Roberts CWM; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Steen H; Department of Pathology, Boston Children's Hospital, Boston, MA, USA., Mullen E; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Jackson SP; The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Biochemistry, University of Cambridge, Cambridge, UK.; The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Torrents D; Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center (BSC-CNS), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Weng Z; Program in Bioinformatics and Integrative Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA., Armstrong SA; Cancer Biology & Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medical College, Cornell University, New York, NY, USA.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kentsis A; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. kentsisresearchgroup@gmail.com.; Weill Cornell Medical College, Cornell University, New York, NY, USA. kentsisresearchgroup@gmail.com.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. kentsisresearchgroup@gmail.com.

المصدر: Nature genetics [Nat Genet] 2020 Nov; Vol. 52 (11), pp. 1265.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Hadi K; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA., Yao X; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Tri-institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Behr JM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Tri-institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Deshpande A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Tri-institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Xanthopoulakis C; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Tian H; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA., Kudman S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Rosiene J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA., Darmofal M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Tri-institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10021, USA., DeRose J; New York Genome Center, New York, NY 10013, USA., Mortensen R; New York Genome Center, New York, NY 10013, USA., Adney EM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA., Shaiber A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Gajic Z; New York Genome Center, New York, NY 10013, USA., Sigouros M; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Eng K; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Wala JA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Departments of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; School of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Wrzeszczyński KO; New York Genome Center, New York, NY 10013, USA., Arora K; New York Genome Center, New York, NY 10013, USA., Shah M; New York Genome Center, New York, NY 10013, USA., Emde AK; New York Genome Center, New York, NY 10013, USA., Felice V; New York Genome Center, New York, NY 10013, USA., Frank MO; New York Genome Center, New York, NY 10013, USA; Laboratory of Molecular Neuro-Oncology and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA., Darnell RB; New York Genome Center, New York, NY 10013, USA; Laboratory of Molecular Neuro-Oncology and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA., Ghandi M; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Huang F; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; School of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Dewhurst S; Laboratory of Cell Biology and Genetics, The Rockefeller University, New York, NY 10065, USA., Maciejowski J; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., de Lange T; Laboratory of Cell Biology and Genetics, The Rockefeller University, New York, NY 10065, USA., Setton J; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Riaz N; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Reis-Filho JS; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Powell S; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Knowles DA; New York Genome Center, New York, NY 10013, USA; Department of Computer Science, Columbia University, New York, NY 10027, USA., Reznik E; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Mishra B; Departments of Computer Science, Mathematics and Cell Biology, Courant Institute and NYU School of Medicine, New York University, New York, NY 10012, USA., Beroukhim R; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Departments of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Zody MC; New York Genome Center, New York, NY 10013, USA., Robine N; New York Genome Center, New York, NY 10013, USA., Oman KM; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Sanchez CA; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Kuhner MK; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA., Smith LP; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA., Galipeau PC; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Paulson TG; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Reid BJ; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA., Li X; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Wilkes D; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Sboner A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Mosquera JM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Elemento O; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Imielinski M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA. Electronic address: mski@mskilab.org.

المصدر: Cell [Cell] 2020 Oct 01; Vol. 183 (1), pp. 197-210.e32.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Genomic Structural Variation/*genetics , Genomics/*methods , Neoplasms/*genetics, Chromosome Inversion/genetics ; Chromothripsis ; DNA Copy Number Variations/genetics ; Gene Rearrangement/genetics ; Genome, Human/genetics ; Humans ; Mutation/genetics ; Whole Genome Sequencing/methods

المؤلفون: Frank MO; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA., Koyama T; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Rhrissorrakrai K; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Robine N; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Utro F; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Emde AK; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Chen BJ; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Google, 76 9th Avenue, New York, NY, 10011, USA., Arora K; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Shah M; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Geiger H; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Felice V; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Dikoglu E; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA., Rahman S; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Fang X; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Vacic V; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: 23&Me, 899 W Evelyn Ave, Mountain View, CA, 94041, USA., Bergmann EA; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Max Planck Institute of Immunobiology and Epigenetics, Stübeweg 51, D-79108, Freiburg, Germany., Moore Vogel JL; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.; Present address: The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA, 92037, USA., Reeves C; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Khaira D; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Calabro A; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: The Tisch Cancer Institute, 1470 Madison Avenue, New York, NY, 10029, USA., Kim D; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Lamendola-Essel MF; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Esteves C; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Harvard Medical School, 10 Shattuck Street, Boston, MA, 02115, USA., Agius P; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Stolte C; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Boockvar J; Northwell Health, Lenox Hill Hospital, 100 E. 77th Street, New York, NY, 10075, USA., Demopoulos A; Northwell Health, The Brain Tumor Center, 450 Lakeville Road, Lake Success, Lakeville, NY, 11042, USA., Placantonakis DG; New York University, School of Medicine, 550 First Avenue, New York, NY, 10016, USA., Golfinos JG; New York University, School of Medicine, 550 First Avenue, New York, NY, 10016, USA., Brennan C; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Bruce J; Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA., Lassman AB; Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA., Canoll P; Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA., Grommes C; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Daras M; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Diamond E; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Omuro A; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.; Present address: Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA., Pentsova E; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Orange DE; Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.; Hospital for Special Surgery, 535 E. 70th Street, New York, NY, 10021, USA., Harvey SJ; IBM Watson Health, NW Broken Sound Bkwy, Boca Raton, FL, 33487, USA., Posner JB; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Michelini VV; IBM Watson Health, NW Broken Sound Bkwy, Boca Raton, FL, 33487, USA., Jobanputra V; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA., Zody MC; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Kelly J; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Parida L; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Wrzeszczynski KO; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Royyuru AK; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Darnell RB; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA. darnelr@rockefeller.edu.; Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA. darnelr@rockefeller.edu.; Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA. darnelr@rockefeller.edu.

المصدر: BMC medical genomics [BMC Med Genomics] 2019 Aug 02; Vol. 12 (1), pp. 114. Date of Electronic Publication: 2019 Aug 02.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium: Internet ISSN: 1755-8794 (Electronic) Linking ISSN: 17558794 NLM ISO Abbreviation: BMC Med Genomics Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: McNeer NA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Philip J; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Geiger H; New York Genome Center, New York, NY, USA., Ries RE; Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Lavallée VP; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Walsh M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shah M; New York Genome Center, New York, NY, USA., Arora K; New York Genome Center, New York, NY, USA., Emde AK; New York Genome Center, New York, NY, USA., Robine N; New York Genome Center, New York, NY, USA., Alonzo TA; Department of Biostatistics, University of Southern California, Los Angeles, CA, USA., Kolb EA; Nemours Center for Cancer and Blood Disorders, Nemours/Alfred Dupont Hospital for Children, Wilmington, DE, USA., Gamis AS; University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA., Smith M; National Cancer Institute, Rockville, MD, USA., Gerhard DS; National Cancer Institute, Rockville, MD, USA., Guidry-Auvil J; National Cancer Institute, Rockville, MD, USA., Meshinchi S; Fred Hutchinson Cancer Research Center, Seattle, WA, USA. smeshinc@fhcrc.org., Kentsis A; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. kentsisresearchgroup@gmail.com.; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. kentsisresearchgroup@gmail.com.; Department of Pediatrics, Pharmacology, and Physiology & Biophysics, Weill Medical College of Cornell University, New York, NY, USA. kentsisresearchgroup@gmail.com.

المصدر: Leukemia [Leukemia] 2019 Aug; Vol. 33 (8), pp. 1934-1943. Date of Electronic Publication: 2019 Feb 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Leukemia, Myeloid, Acute/*drug therapy, Child ; Drug Resistance, Neoplasm ; Genes, Wilms Tumor ; Genes, p53 ; Humans ; Leukemia, Myeloid, Acute/genetics

المؤلفون: Frank MO; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA., Koyama T; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Rhrissorrakrai K; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Robine N; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Utro F; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Emde AK; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Chen BJ; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Google, 76 9th Avenue, New York, NY, 10011, USA., Arora K; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Shah M; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Geiger H; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Felice V; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Dikoglu E; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA., Rahman S; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Fang A; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Vacic V; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: 23&Me, 899 W Evelyn Ave, Mountain View, CA, 94041, USA., Bergmann EA; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Max Planck Institute of Immunobiology and Epigenetics, Stübeweg 51 D-79108, Freiburg, Germany., Vogel JLM; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.; Present address: The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA, 92037, USA., Reeves C; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Khaira D; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Calabro A; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: The Tisch Cancer Institute, 1470 Madison Avenue, New York, NY, 10029, USA., Kim D; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Lamendola-Essel MF; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Esteves C; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Present address: Harvard Medical School, 10 Shattuck Street, Boston, MA, 02115, USA., Agius P; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Stolte C; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Boockvar J; Northwell Health, Lenox Hill Hospital, 100 E. 77th Street, New York, NY, 10075, USA., Demopoulos A; Northwell Health, The Brain Tumor Center, 450 Lakeville Road, Lake Success, Lakeville, NY, 11042, USA., Placantonakis DG; New York University, School of Medicine, 550 First Avenue, New York, NY, 10016, USA., Golfinos JG; New York University, School of Medicine, 550 First Avenue, New York, NY, 10016, USA., Brennan C; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Bruce J; Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA., Lassman AB; Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA., Canoll P; Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA., Grommes C; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Daras M; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Diamond E; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Omuro A; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.; Present address: Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA., Pentsova E; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Orange DE; Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.; Hospital for Special Surgery, 535 E. 70th Street, New York, NY, 10021, USA., Harvey SJ; IBM Watson Health, NW Broken Sound Bkwy, Boca Raton, FL, 33487, USA., Posner JB; Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA., Michelini VV; IBM Watson Health, NW Broken Sound Bkwy, Boca Raton, FL, 33487, USA., Jobanputra V; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA.; Columbia University Medical Center, 710 West 168th Street, New York, NY, 10032, USA., Zody MC; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Kelly J; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Parida L; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Wrzeszczynski KO; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA., Royyuru AK; IBM Thomas J. Watson Research Center, Yorktown Heights, NY, 10598, USA., Darnell RB; New York Genome Center, 101 Avenue of the Americas, New York, NY, 10013, USA. darnelr@rockefeller.edu.; Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA. darnelr@rockefeller.edu.; Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA. darnelr@rockefeller.edu.

المصدر: BMC medical genomics [BMC Med Genomics] 2019 Apr 25; Vol. 12 (1), pp. 56. Date of Electronic Publication: 2019 Apr 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium: Internet ISSN: 1755-8794 (Electronic) Linking ISSN: 17558794 NLM ISO Abbreviation: BMC Med Genomics Subsets: MEDLINE

مواضيع طبية MeSH: Whole Genome Sequencing*, Glioblastoma/*drug therapy , Glioblastoma/*genetics, Adult ; Aged ; Aged, 80 and over ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Molecular Targeted Therapy ; Ploidies ; Reproducibility of Results