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المؤلفون: Gundula Streubel, Ariane Waston, Darrell Andrews, Gerard Cagney, Emilia Jerman, John Crean, Gerard L. Brien, Nayla Munawar, Adrian P. Bracken, Kieran Wynne, Giorgio Oliviero, Benjamin Doyle
المصدر: Oliviero, G, Brien, G L, Waston, A, Streubel, G, Jerman, E, Andrews, D, Doyle, B, Munawar, N, Wynne, K, Crean, J, Bracken, A P & Cagney, G 2016, ' Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells ', Molecular & Cellular Proteomics (MCP), vol. 15, no. 11, pp. 3450-3460 . https://doi.org/10.1074/mcp.M116.062240
مصطلحات موضوعية: Pluripotent Stem Cells, Proteomics, 0301 basic medicine, Embryonal Carcinoma Stem Cells, Cellular differentiation, Embryonal Carcinoma Stem Cells/cytology, Histones/metabolism, macromolecular substances, Cell fate determination, Biochemistry, Interactome, Epigenesis, Genetic, Analytical Chemistry, Protein–protein interaction, Histones, 03 medical and health sciences, Histone H3, Cell Line, Tumor, SUZ12, Humans, Enhancer of Zeste Homolog 2 Protein, Protein Interaction Maps, Molecular Biology, Enhancer of Zeste Homolog 2 Protein/metabolism, biology, Chemistry, Research, Polycomb Repressive Complex 2, Cell Differentiation, Pluripotent Stem Cells/cytology, Polycomb Repressive Complex 2/metabolism, Embryonic stem cell, Neoplasm Proteins, Cell biology, 030104 developmental biology, biology.protein, Proteomics/methods, PRC2, Transcription Factors
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0f7f7099eeeafcad6d3e019e30ce0f
https://doi.org/10.1074/mcp.m116.062240 -
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المؤلفون: Kieran Wynne, Giorgio Olivero, Gundula Streubel, Emilia Jerman, Gerard Cagney, Adrian P. Bracken, Nayla Munawar, Benjamin Doyle
المصدر: PROTEOMICS. 15:3603-3612
مصطلحات موضوعية: Proteomics, Protein subunit, Immunoblotting, Biology, Biochemistry, Molecular biology, Chromatin, Native Polyacrylamide Gel Electrophoresis, Electrophoresis, HEK293 Cells, FLAG-tag, Affinity chromatography, Cytoplasm, Multiprotein Complexes, Protein purification, biology.protein, Humans, PRC2, Molecular Biology
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المؤلفون: Evan Healy, Raphaël Margueron, Aoife McLysaght, Haruhiko Koseki, Luciano Di Croce, Darren J. Fitzpatrick, Emilia Jerman, Orla Deevy, Manabu Nakayama, Kieran Wynne, Giorgio Oliviero, Gundula Streubel, Karsten Hokamp, Adrian P. Bracken, Claudio Ciferri, Ariane Watson, Indigo Pratt-Kelly, Christine S. Huang, Paul Chammas, Marlena Mucha, Tomoyuki Ishikura, Eleanor Glancy, Gerard Cagney, Eric Conway, Shinsuke Ito, Alan M. Rice, Daniel Holoch, Yoko Koseki
المصدر: Molecular cell. 70(3)
مصطلحات موضوعية: 0301 basic medicine, Gene isoform, macromolecular substances, Biology, Methylation, Cell Line, Histones, 03 medical and health sciences, Histone H3, Mice, Neoplasms, SUZ12, Animals, Humans, RBBP4, Amino Acid Sequence, Molecular Biology, Gene, Genetics, EZH2, Polycomb Repressive Complex 2, Cell Differentiation, Cell Biology, Methyltransferases, Repressor Proteins, 030104 developmental biology, HEK293 Cells, Vertebrates, biology.protein, LCOR, PRC2, Sequence Alignment
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المؤلفون: Chris M. Egan, Eiseart J. Dunne, Maike C. Jürgens, Lianhua Piao, Gerard Cagney, Siobhán A. Turner, Neil M. Ferguson, Xiaobing Shi, Kieran Wynne, Gerard L. Brien, Amanda J. Lohan, Adrian P. Bracken, Guillermo Gambero, Krishna M. Sinha, Brendan J. Loftus, Emilia Jerman, David J. O'Connell
المصدر: Nature Structural & Molecular Biology. 19:1273-1281
مصطلحات موضوعية: Genetics, Tudor domain, biology, Cellular differentiation, macromolecular substances, Chromatin, Histone H3, Structural Biology, Demethylase activity, biology.protein, Polycomb-group proteins, Demethylase, PRC2, Molecular Biology
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المؤلفون: Fatima Aloraifi, Karsten Hokamp, Adrian P. Bracken, Louise Flanagan, Ashwini Maratha, Gerard L. Brien, Karin Jirström, Amanda J. Lohan, James Geraghty, Cecily Quinn, Brendan J. Loftus, Yue Fan, Emilia Jerman, William M. Gallagher, Marie Fridberg, Martha R. Stampfer, Stephen F. Madden, Eiseart J. Dunne, Fiona Lanigan, James C. Garbe
المصدر: The FEBS journal, vol 282, iss 18
Lanigan, F; Brien, GL; Fan, Y; Madden, SF; Jerman, E; Maratha, A; et al.(2015). Delineating transcriptional networks of prognostic gene signatures refines treatment recommendations for lymph node-negative breast cancer patients. FEBS Journal, 282(18), 3455-3473. doi: 10.1111/febs.13354. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/1pk9r3h7مصطلحات موضوعية: Oncology, medicine.medical_treatment, Messenger, p16, Medical Biochemistry and Metabolomics, Biochemistry, Cohort Studies, Mice, Risk Factors, Gene expression, Receptors, Transcriptional regulation, 80 and over, cellular senescence, Gene Regulatory Networks, RNA, Neoplasm, Promoter Regions, Genetic, Cells, Cultured, Cellular Senescence, Aged, 80 and over, Cultured, Middle Aged, Prognosis, Phenotype, Mammary Glands, Receptors, Estrogen, Cell Aging, Lymphatic Metastasis, Female, Lymph, Human, Senescence, Adult, medicine.medical_specialty, Biochemistry & Molecular Biology, Cells, proliferation, Breast Neoplasms, Promoter Regions, Medicinal and Biomolecular Chemistry, Breast cancer, breast cancer, Genetic, Internal medicine, medicine, Animals, Humans, RNA, Messenger, Mammary Glands, Human, Molecular Biology, Gene, Cell Proliferation, Aged, Chemotherapy, business.industry, Genes, p16, Cell Biology, medicine.disease, Estrogen, Genes, Tissue Array Analysis, Immunology, RNA, Neoplasm, OncoMasTR, Biochemistry and Cell Biology, business, Master Transcriptional Regulators
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97eeb0524d6e54ea9ce5b2a3b98144a2
https://escholarship.org/uc/item/1pk9r3h7 -
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المؤلفون: Elisa Fadda, Eric Conway, Aoife McLysaght, Adrian P. Bracken, Emilia Jerman, Scott A. Armstrong, Conor J. Kearney, Alan M. Rice, Andrei V. Krivtsov, David J. O'Connell, Simon S. McDade, Evan Healy, Gerard L. Brien, Darragh O'Donovan, Andrew Flaus, Seamus J. Martin
المصدر: Genesdevelopment. 29(21)
مصطلحات موضوعية: p53, senescence, Polycomb-Group Proteins, Plasma protein binding, self-renewal, Mice, 0302 clinical medicine, cellular senescence, transcriptional regulation, phd reader domain, Cells, Cultured, Genetics, complexes, 0303 health sciences, neofunctionalization, Protein Stability, ink4a-arf locus, Chromatin, Cell biology, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, group proteins, 030220 oncology & carcinogenesis, polycomb-like, PRC2, bmi-1, Protein Binding, Research Paper, macromolecular substances, Biology, embryonic stem-cells, DNA-binding protein, developmental regulators, 03 medical and health sciences, Polycomb-group proteins, Animals, Humans, Transcription factor, Cyclin-Dependent Kinase Inhibitor p16, cellular quiescence, 030304 developmental biology, Cell Proliferation, E2F Transcription Factors, Protein Structure, Tertiary, growth arrest, biology.protein, Ectopic expression, Tumor Suppressor Protein p53, Function (biology), Developmental Biology, Transcription Factors
وصف الملف: text
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee123bebcef13312e904991ed6a3ccc
https://pubmed.ncbi.nlm.nih.gov/26494712 -
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المؤلفون: Gerard L. Brien, Bracken P. Adrian, Emilia Jerman, Matthew Campbell
المصدر: Cancer Research. 73:A28-A28
مصطلحات موضوعية: Cancer Research, Tudor domain, biology, EZH2, Cancer, macromolecular substances, Bioinformatics, medicine.disease, Chromatin, Oncology, Cancer research, biology.protein, medicine, Ectopic expression, Epigenetics, PRC1, PRC2
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bb26fc1af1beabe8efb0f8f48b5b2ded
https://doi.org/10.1158/1538-7445.cec13-a28
