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المؤلفون: Jean-Michel Longpré, Fernand-Pierre Gendron, Philippe Sarret, Mélissa Girard, Guillaume Arguin, Steve Dagenais Bellefeuille, Morgane Placet, Rebecca L. Brouillette, Emilie Eiselt
المصدر: Journal of Cellular Physiology. 235:9676-9690
مصطلحات موضوعية: 0301 basic medicine, Physiology, Chemistry, Kinase, Clinical Biochemistry, Cell migration, Cell Biology, Cofilin, Actin cytoskeleton, Cell biology, Focal adhesion, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Signal transduction, Receptor, Filopodia
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المؤلفون: Alain Larocque, Louis Gendron, Anthony Regina, Valérie Otis, Emilie Eiselt, Gaoqiang Yang, Karine Belleville, Michel Demeule, Philippe Sarret
المصدر: Journal of Pharmacology and Experimental Therapeutics. 374:52-61
مصطلحات موضوعية: Male, Nociception, 0301 basic medicine, Metabolite, Analgesic, Pharmacology, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Animals, Medicine, Potency, Morphine Derivatives, business.industry, Biological Transport, Analgesics, Opioid, 030104 developmental biology, Transcytosis, chemistry, Opioid, Blood-Brain Barrier, Drug delivery, Morphine, Molecular Medicine, Administration, Intravenous, Gastrointestinal Motility, Peptides, business, 030217 neurology & neurosurgery, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02b8a1707d840bda30350d41af5fe49
https://doi.org/10.1124/jpet.119.263566 -
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المؤلفون: Simon Gonzalez, Dirk Tourwé, Philippe Sarret, Mariana Spetea, Florine Cavelier, Santo Previti, Charlotte Martin, Linda Kunze, Mélanie Vivancos, Stevany Louis, Louis Gendron, Elke Dewolf, Maria Dumitrascuta, Steven Ballet, Emilie Eiselt, Annalisa Blasiol
المساهمون: Chemistry, Faculty of Economic and Social Sciences and Solvay Business School, WE Academic Unit, Vriendenkring VUB, High Resolution NMR Centre, Organic Chemistry, Vrije Universiteit Brussel [Bruxelles] (VUB), University of Innsbruck, Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Université de Sherbrooke (UdeS)
المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (21), pp.12929-12941. ⟨10.1021/acs.jmedchem.0c01376⟩مصطلحات موضوعية: Agonist, Male, medicine.drug_class, Stereochemistry, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Receptors, Opioid, mu, Pain, Peptide, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, 01 natural sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Receptors, Opioid, delta, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Receptors, Neurotensin, Amino Acid Sequence, Receptor, Peptide sequence, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Tetrapeptide, Chemistry, 0104 chemical sciences, Amino acid, 010404 medicinal & biomolecular chemistry, Disease Models, Animal, Drug Design, Molecular Medicine, Peptides, Oligopeptides, Neurotensin, Protein Binding
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المؤلفون: Louis Gendron, Cecilia Betti, Magali Chartier, Simon Gonzalez, Steven Ballet, Jean-Michel Longpré, Florine Cavelier, Charlotte Martin, Dirk Tourwé, Emilie Eiselt, Philippe Sarret
المساهمون: Université de Cergy Pontoise (UCP), Université Paris-Seine, CHU Toulouse [Toulouse], Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Department of Organic Chemistry, Vrije Universiteit Brussel (VUB), Montreal Neurological Institute and Hospital, McGill University = Université McGill [Montréal, Canada], Department of Physiology and Biophysics, Université de Sherbrooke (UdeS), Chemistry, WE Academic Unit, Vriendenkring VUB, High Resolution NMR Centre, Organic Chemistry
المصدر: ACS Chemical Neuroscience
ACS Chemical Neuroscience, American Chemical Society (ACS), 2019, 10 (11), pp.4535-4544. ⟨10.1021/acschemneuro.9b00390⟩مصطلحات موضوعية: Male, Physiology, Cognitive Neuroscience, Analgesic, GPCR ligands, CHO Cells, Hypothermia, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Pharmacology, Biochemistry, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, 0302 clinical medicine, Cricetinae, medicine, Animals, Humans, Receptors, Neurotensin, Tyrosine, Receptor, Neurotensin, Receptor selectivity, ED50, ComputingMilieux_MISCELLANEOUS, Pain Measurement, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Dose-Response Relationship, Drug, Neurotensin peptides, analgesia, Biological activity, Cell Biology, General Medicine, Rats, 3. Good health, Amino acid, chemistry, NTS2, Hypotension, medicine.symptom, unnatural amino acids, 030217 neurology & neurosurgery, Protein Binding
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المؤلفون: Louis Gendron, Véronique Blais, Philippe Sarret, Jérôme Côté, Jean-Michel Longpré, Emilie Eiselt
المصدر: European journal of pharmacology. 848
مصطلحات موضوعية: 0301 basic medicine, Male, Analgesic, Receptors, Opioid, mu, Pharmacology, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Medicine, Animals, Receptors, Neurotensin, Neurotensin receptor, Adverse effect, Neurotensin, Pain Measurement, Dose-Response Relationship, Drug, Morphine, business.industry, Effective dose (pharmacology), Peptide Fragments, 3. Good health, Rats, Analgesics, Opioid, 030104 developmental biology, Nociception, chemistry, Opioid, Drug Therapy, Combination, business, Peptides, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Wim Bert Griet Schepens, Peter W. Schiller, Steven Ballet, Emilie Eiselt, Nga N. Chung, Tom Willemse, Louis Gendron, Jean-Michel Longpré, Philippe Sarret, Karlijn Hollanders, Véronique Blais, Bert U. W. Maes, Herman van Vlijmen, Brain Holleran
المصدر: Bioorganic and medicinal chemistry letters
مصطلحات موضوعية: Male, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Guinea Pigs, Receptors, Opioid, mu, Pharmaceutical Science, Phenylalanine, 010402 general chemistry, Ligands, 01 natural sciences, Biochemistry, Article, Rats, Sprague-Dawley, Mice, Opioid receptor, Receptors, Opioid, delta, Drug Discovery, Side chain, Structural isomer, medicine, Moiety, Animals, Humans, Opioid peptide, Biology, Molecular Biology, Oligopeptide, Molecular Structure, 010405 organic chemistry, Chemistry, Pharmacology. Therapy, Organic Chemistry, Affinities, 0104 chemical sciences, Analgesics, Opioid, HEK293 Cells, Molecular Medicine, Oligopeptides
وصف الملف: pdf
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المؤلفون: P. Sarret, Louis Gendron, Dirk Tourwé, Robin Van Den Hauwe, Steven Ballet, Emilie Eiselt, Olivier Van der Poorten
المصدر: Proceedings of the 35th European Peptide Symposium.
مصطلحات موضوعية: chemistry.chemical_compound, Dipeptide, Chemistry, Peptidomimetic, Combinatorial chemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23b7dbb5dd6162f1881c4a73a2364e7a
https://doi.org/10.17952/35eps.2018.178 -
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المؤلفون: Louis Gendron, Dirk Tourwé, Frédéric Bihel, Nga N. Chung, Peter W. Schiller, Olivier Van der Poorten, Cecilia Betti, Robin Van Den Hauwe, Karel Guillemyn, Emilie Eiselt, Steven Ballet, François Hallé, Philippe Sarret
المساهمون: Laboratoire d'Innovation Thérapeutique (LIT), Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Department of Organic Chemistry, Vrije Universiteit Brussel (VUB), Department of Physiology and Biophysics, Université de Sherbrooke (UdeS), Montreal Neurological Institute and Hospital, McGill University = Université McGill [Montréal, Canada], Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)
المصدر: ACS Medicinal Chemistry Letters
ACS Medicinal Chemistry Letters, American Chemical Society, 2017, 8 (11), pp.1177-1182. ⟨10.1021/acsmedchemlett.7b00347⟩مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Tetrapeptide, 010405 organic chemistry, Stereochemistry, Organic Chemistry, Peptide, Dermorphin, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, 01 natural sciences, Biochemistry, Combinatorial chemistry, ANT, 0104 chemical sciences, Amino acid, 03 medical and health sciences, chemistry.chemical_compound, Residue (chemistry), 030104 developmental biology, chemistry, Drug Discovery, Receptor, Selectivity, ComputingMilieux_MISCELLANEOUS
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المؤلفون: Roman G. Deschaumes, Céline Salsac, Cédric Raoul, Emilie Eiselt, Melissa Bowerman, Emmanuelle Coque, Alexandre Brodovitch, Frédérique Scamps, Linda C. Burkly
المصدر: Human Molecular Genetics. 24:3440-3456
مصطلحات موضوعية: Microgliosis, Receptors, Tumor Necrosis Factor, Mice, Superoxide Dismutase-1, Gliosis, Amyotrophic lateral sclerosis, Genetics (clinical), Cytokine TWEAK, Mice, Knockout, Motor Neurons, Cell Death, General Medicine, Anatomy, Up-Regulation, Astrogliosis, Muscular Atrophy, medicine.anatomical_structure, Spinal Cord, TWEAK Receptor, Tumor Necrosis Factors, Microglia, Signal Transduction, Astrocyte, SOD1, Antigens, Differentiation, Myelomonocytic, Mice, Transgenic, Receptors, Cell Surface, Biology, Motor Endplate, Life Expectancy, Atrophy, Antigens, CD, Genetics, medicine, Animals, Muscle, Skeletal, Molecular Biology, Cell Proliferation, Interleukin-6, Superoxide Dismutase, Amyotrophic Lateral Sclerosis, Skeletal muscle, medicine.disease, Disease Models, Animal, Gene Expression Regulation, nervous system, Astrocytes, Mutation, Neuroscience, Gene Deletion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5ec2ed46d7905352678525229dfa64
https://doi.org/10.1093/hmg/ddv094 -
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المؤلفون: Bert U. W. Maes, Emilie Eiselt, Tom Willemse, Jean-Michel Longpré, Wim Bert Griet Schepens, Philippe Sarret, Brian J. Holleran, Véronique Blais, Peter W. Schiller, Nga N. Chung, Karlijn Hollanders, Steven Ballet, Louis Gendron, Herman van Vlijmen
المصدر: Bioorganic & Medicinal Chemistry Letters. 28:3418
مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Agonism, Opioid peptide, Molecular Biology, Biochemistry, Chemical space
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