المؤلفون: Emily A. Dickie, Federica Giordani, Matthew K. Gould, Pascal Mäser, Christian Burri, Jeremy C. Mottram, Srinivasa P. S. Rao, Michael P. Barrett

المصدر: Tropical Medicine and Infectious Disease, Vol 5, Iss 1, p 29 (2020)

مصطلحات موضوعية: human african trypanosomiasis, sleeping sickness, elimination, chemotherapy, fexinidazole, pafuramidine, acoziborole, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2414-6366/5/1/29; https://doaj.org/toc/2414-6366

URL الوصول: https://doaj.org/article/fcec70764b7842eda3b0f5326af38879

المؤلفون: Edubiel A Alpizar-Sosa, Nur Raihana Binti Ithnin, Wenbin Wei, Andrew W Pountain, Stefan K Weidt, Anne M Donachie, Ryan Ritchie, Emily A Dickie, Richard J S Burchmore, Paul W Denny, Michael P Barrett

المصدر: PLoS Neglected Tropical Diseases, Vol 16, Iss 9, p e0010779 (2022)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/d236c07b263b428594e99eab4248e1b2

المؤلفون: Peter E Cockram, Emily A Dickie, Michael P Barrett, Terry K Smith

المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008928 (2020)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/76a35d2415834a44aacc59927986199e

المؤلفون: Edubiel A. Alpizar-Sosa, Nur Raihana Binti Ithnin, Wenbin Wei, Andrew W. Pountain, Stefan K. Weidt, Anne M. Donachie, Ryan Ritchie, Emily A. Dickie, Richard J. S. Burchmore, Paul W. Denny, Michael P. Barrett

المصدر: PLOS Neglected Tropical Diseases, 2022, Vol.16(9), pp.e0010779 [Peer Reviewed Journal]

مصطلحات موضوعية: Fatty Acid Desaturases, Nystatin, Leishmania mexicana, Public Health, Environmental and Occupational Health, Antiprotozoal Agents, Serum Albumin, Bovine, Polyenes, Mice, Sterols, Oxidative Stress, Infectious Diseases, Glucose, Transferases, Amphotericin B, Animals

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211f168830cff69dc45cb173585a9956
http://dro.dur.ac.uk/37233/

المؤلفون: Edubiel A. Alpizar-Sosa, Nur Raihana Binti Ithnin, Wenbin Wei, Andrew W. Pountain, Stefan K. Weidt, Anne M. Donachie, Ryan Ritchie, Emily A. Dickie, Richard J. S. Burchmore, Paul W. Denny, Michael P. Barrett

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::33a4174b5f5c9a2005e18edfe3074226
https://doi.org/10.1101/2021.12.08.471712

المؤلفون: Siddharth Jayaraman, Edith Paxton, Harry P. de Koning, Kathryn Crouch, Omar A. Alfituri, Pieter C. Steketee, Catarina Gadelha, Ryan Ritchie, Emily A. Dickie, Michael P. Barrett, Achim Schnaufer, Bill Wickstead, T.G Rowan, Liam J. Morrison, Georgina Awuah-Mensah, James Iremonger

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 7, p e1009734 (2021)
Steketee, P, Dickie, E A, Iremonger, J, Crouch, K, Paxton, E, Jayaraman, S, Alfituri, O, Awuah-Mensah, G, Ritchie, R, Schnaufer, A, Rowan, T, De Koning, H P, Gadelha, C, Wickstead, B, Barrett, M P & Morrison, L 2021, ' Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition ', PLoS Pathogens, vol. 17, no. 7, e1009734 . https://doi.org/10.1371/journal.ppat.1009734

مصطلحات موضوعية: Trypanosoma congolense, Mitochondrial pyruvate dehydrogenase complex, Biochemistry, chemistry.chemical_compound, Mice, Glucose Metabolism, Metabolites, Glycolysis, African trypanosomiasis, Biology (General), Protozoans, 0303 health sciences, biology, Organic Compounds, Monosaccharides, Fatty Acids, Eukaryota, Genomics, Ketones, Lipids, 3. Good health, Chemistry, Saturated fatty acid, Physical Sciences, Carbohydrate Metabolism, Metabolic Labeling, Transcriptome Analysis, Research Article, Pyruvate, Trypanosoma, QH301-705.5, Immunology, Trypanosoma brucei brucei, Carbohydrates, Trypanosoma brucei, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Virology, parasitic diseases, medicine, Trypanosoma Brucei, Genetics, Animals, Molecular Biology Techniques, Molecular Biology, Fatty acid synthesis, 030304 developmental biology, Lipid Regulating Agents, 030306 microbiology, Organic Chemistry, Organisms, Chemical Compounds, Biology and Life Sciences, Computational Biology, Metabolism, RC581-607, biology.organism_classification, medicine.disease, Genome Analysis, Parasitic Protozoans, Glucose, Trypanosomiasis, African, chemistry, Cell Labeling, Parasitology, Immunologic diseases. Allergy, Acids, Trypanosoma Brucei Gambiense

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09479fd9ae271c20c8eba737e0d0d06b
http://europepmc.org/articles/PMC8384185

المؤلفون: Anabela Cordeiro-da-Silva, Louise L. Major, Mónica Sá, Paola Ciapetti, Jane MacDougall, Terry K. Smith, Fabrice Ciesielski, Joana Tavares, Nuno Santarém, Nathalie Trouche, Emily A. Dickie, Iain K. Pemberton, Céline Ronin

المساهمون: European Commission, University of St Andrews. Arctic Research Centre, University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex

المصدر: Antimicrob Agents Chemother

مصطلحات موضوعية: RM, Inhibitor, European community, Anti parasitic, Protein crystal structure, 030231 tropical medicine, Drug target, NDAS, 03 medical and health sciences, Ribose 5-phosphate isomerase, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Political science, parasitic diseases, Humans, Pharmacology (medical), QD, Amino Acid Sequence, Leishmania infantum, Mechanisms of Action: Physiological Effects, Leishmaniasis, Neglected tropical diseases, 030304 developmental biology, Pharmacology, 0303 health sciences, biology, QR Microbiology, biology.organism_classification, QD Chemistry, Virology, Anti-parasitic, RM Therapeutics. Pharmacology, QR, Infectious Diseases, Ribose-5-phosphate isomerase, Pharmaceutical Preparations, Screening, Ribosemonophosphates, Thermal shift

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03593d13f339e842adf9b91dc2d37197
https://hdl.handle.net/10023/24164

المؤلفون: John G. Mina, Emily A. Dickie, Edubiel A. Alpizar-Sosa, Paul W. Denny, Chris Brown, Maria Paula Gonçalves Borsodi, Cláudia P. Figueiredo, Wenbin Wei, Robson Coutinho-Silva, Douglas O. Escrivani, Emanuelle V. de Lima, Bartira Rossi-Bergmann, Andy Merritt, Amjed Qays Al-Qaisi, Patrick G. Steel, Michael P. Barrett, Rebecca L Charlton, Terry K. Smith

المساهمون: Medical Research Council, University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex

المصدر: ACS infectious diseases, 2021, Vol.7(1), pp.47-63 [Peer Reviewed Journal]

مصطلحات موضوعية: 0301 basic medicine, Drug, media_common.quotation_subject, 030106 microbiology, Pharmacology, Ceramide, 03 medical and health sciences, SDG 3 - Good Health and Well-being, In vivo, IPCS, RA0421, RA0421 Public health. Hygiene. Preventive Medicine, Clemastine Fumarate, Leishmania major, QD, Amastigote, media_common, Leishmania, Sphingolipids, biology, Chemistry, Clemastine fumarate, DAS, biology.organism_classification, QD Chemistry, Sphingolipid, 3. Good health, Drug repositioning, 030104 developmental biology, Infectious Diseases, Repurposing

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68269bc68eb5c08c88f7c95185bf53a9
https://hdl.handle.net/10023/21321

المؤلفون: H. P. de Koning, Siddharth Jayaraman, Emily A. Dickie, Kathryn Crouch, Liam J. Morrison, J. Iremonger, Bill Wickstead, Edith Paxton, Pieter C. Steketee, Ryan Ritchie, Michael P. Barrett, Achim Schnaufer, Omar A. Alfituri, Catarina Gadelha, Georgina Awuah-Mensah

مصطلحات موضوعية: chemistry.chemical_compound, biology, Fatty acid metabolism, chemistry, Biochemistry, Trypanosoma, Glycolysis, Mitochondrial pyruvate dehydrogenase complex, Oxidative phosphorylation, Metabolism, Trypanosoma brucei, biology.organism_classification, Fatty acid synthesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::08e7f434206035909eba3ce416f25d49
https://doi.org/10.1101/2021.01.05.425368

المؤلفون: John G M, Mina, Rebecca L, Charlton, Edubiel, Alpizar-Sosa, Douglas O, Escrivani, Christopher, Brown, Amjed, Alqaisi, Maria Paula G, Borsodi, Claudia P, Figueiredo, Emanuelle V, de Lima, Emily A, Dickie, Wenbin, Wei, Robson, Coutinho-Silva, Andy, Merritt, Terry K, Smith, Michael P, Barrett, Bartira, Rossi-Bergmann, Paul W, Denny, Patrick G, Steel

المصدر: ACS Infectious Diseases

مصطلحات موضوعية: Leishmania, sphingolipids, Antiprotozoal Agents, repurposing, Article, Mice, clemastine fumarate, Pharmaceutical Preparations, IPCS, Animals, Clemastine, ceramide, Leishmaniasis, Inositol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::32b04de81c5c385197e8530b2453b645
https://pubmed.ncbi.nlm.nih.gov/33291887