نتائج البحث - "Emily M, Cheney"

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دورية أكاديمية

Combination therapy targeting both innate and adaptive immunity improves survival in a pre-clinical model of ovarian cancer

المؤلفون: Christina A. Hartl, Adrian Bertschi, Regina Bou Puerto, Carolin Andresen, Emily M. Cheney, Elizabeth A. Mittendorf, Jennifer L. Guerriero, Michael S. Goldberg

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)

مصطلحات موضوعية: Ovarian cancer, Cancer immunotherapy, Combination therapy, CD4+ T cells, Innate immunity, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-019-0654-5; https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/bd971baaf2314dd4906974aae84403c4

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Combination therapy targeting both innate and adaptive immunity improves survival in a pre-clinical model of ovarian cancer

المؤلفون: Adrian Bertschi, Carolin Andresen, Emily M. Cheney, Elizabeth A. Mittendorf, Christina A. Hartl, Jennifer L. Guerriero, Michael S. Goldberg, Regina Bou Puerto

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, Cancer Research, Myeloid, medicine.medical_treatment, Cancer immunotherapy, Adaptive Immunity, B7-H1 Antigen, Carboplatin, Mice, Antineoplastic Agents, Immunological, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Tumor Microenvironment, Immunology and Allergy, Cytotoxic T cell, Molecular Targeted Therapy, Ovarian Neoplasms, Innate immunity, Acquired immune system, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Combined Modality Therapy, Interleukin-10, Gene Expression Regulation, Neoplastic, Treatment Outcome, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Female, Nucleotides, Cyclic, Research Article, Paclitaxel, Immunology, lcsh:RC254-282, 03 medical and health sciences, Immune system, Ovarian cancer, medicine, Animals, Humans, Combination therapy, Pharmacology, Tumor microenvironment, business.industry, Gene Expression Profiling, Immunotherapy, medicine.disease, Survival Analysis, Xenograft Model Antitumor Assays, Immunity, Innate, CD4+ T cells, 030104 developmental biology, Cancer research, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8c8985bc2f3964a34605af7328bf3a
http://link.springer.com/article/10.1186/s40425-019-0654-5

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3

PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer

المؤلفون: Aditi Kothari, Jos Jonkers, Sven Rottenberg, Jennifer L. Guerriero, Tanvi Visal, Jessica A. Castrillon, Jocelin Pinto, Gerburg M. Wulf, Anita K. Mehta, Constantia Pantelidou, Michelle K. Li, Geoffrey I. Shapiro, Olmo Sonzogni, Dan Wang, Mateus De Oliveria Taveira, Emily M. Cheney, Peter Bouwman

المصدر: Cancer Discovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01134756315e2d20348a7260882edd14
https://doi.org/10.1158/2159-8290.cd-18-1218

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860 Targeting immunosuppressive macrophages overcomes PARP-inhibitor resistance in BRCA1-associated triple-negative breast cancer

المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366006b16db55dab263610298931c15d
https://doi.org/10.1136/jitc-2020-sitc2020.0860

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Use of Murine Models to Identify Tumor Immune Components that Correlate with Response to Immunotherapy in Breast Cancer

المؤلفون: Jennifer L. Guerriero, Emily M. Cheney, Anthony Letai, Eric M. Miller, Alaba Sotayo, Anita K. Mehta, Jessica A. Castrillon, Elizabeth A. Mittendorf

مصطلحات موضوعية: Breast cancer, Immune system, business.industry, medicine.medical_treatment, medicine, Cancer research, Immunotherapy, medicine.disease, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::72b5dc1ec17a100305f2460496033b3b
https://doi.org/10.21203/rs.3.rs-57679/v1

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Comparing syngeneic and autochthonous models of breast cancer to identify tumor immune components that correlate with response to immunotherapy in breast cancer

المؤلفون: Emily M. Cheney, Jessica Castrillon Lal, Alaba Sotayo, Elizabeth A. Mittendorf, Anthony Letai, Madeline G Townsend, Madisson Oliwa, Jennifer L. Guerriero, Eric M. Miller, Anita K. Mehta

المصدر: Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-24 (2021)

مصطلحات موضوعية: medicine.medical_treatment, CD3, T-Lymphocytes, Mice, Transgenic, Biology, Syngeneic tumor models, Mice, Immune system, Breast cancer, Lymphocytes, Tumor-Infiltrating, Surgical oncology, Cell Line, Tumor, medicine, Tumor Microenvironment, Animals, Myeloid Cells, Immune Checkpoint Inhibitors, RC254-282, Preclinical mouse models, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Mammary Neoplasms, Experimental, Immunotherapy, medicine.disease, Immune checkpoint, Blockade, Transplantation, Isogeneic, Drug Resistance, Neoplasm, biology.protein, Cancer research, Jessica Castrillon Lal and Madeline G. Townsend contributed equally to this work, Female, Transcriptome, CD8, Neoplasm Transplantation, Immune checkpoint blockade, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4ef6954fbba8c7c545a17d9d4ccf31
https://pubmed.ncbi.nlm.nih.gov/34353349

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PARP Inhibitor Efficacy Depends on CD8

المؤلفون: Constantia, Pantelidou, Olmo, Sonzogni, Mateus, De Oliveria Taveira, Anita K, Mehta, Aditi, Kothari, Dan, Wang, Tanvi, Visal, Michelle K, Li, Jocelin, Pinto, Jessica A, Castrillon, Emily M, Cheney, Peter, Bouwman, Jos, Jonkers, Sven, Rottenberg, Jennifer L, Guerriero, Gerburg M, Wulf, Geoffrey I, Shapiro

المصدر: Cancer Discov

مصطلحات موضوعية: BRCA2 Protein, BRCA1 Protein, Membrane Proteins, Triple Negative Breast Neoplasms, CD8-Positive T-Lymphocytes, Poly(ADP-ribose) Polymerase Inhibitors, Immunohistochemistry, Article, Lymphocytes, Tumor-Infiltrating, Tumor Microenvironment, Humans, Female, Biomarkers, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::43498aad90d39ccec8fbd85783088c53
https://pubmed.ncbi.nlm.nih.gov/31015319

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Abstract A105: PARP inhibition modulates the infiltration, phenotype, and function of tumor-associated macrophages (TAMs) in BRCA-associated breast cancer and can be augmented by harnessing the antitumor potential of TAMs

المصدر: Cancer Immunology Research. 8:A105-A105

مصطلحات موضوعية: Cancer Research, Immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e807e39215e6ed7d2c58840f9c8b11af
https://doi.org/10.1158/2326-6074.tumimm19-a105

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Abstract A81: Identifying cellular immune components that correlate with response to immunotherapy in breast cancer using murine models

المؤلفون: Jennifer L. Guerriero, Anita K. Mehta, Anthony Letai, Emily M. Cheney, Alaba Sotayo, Jessica A. Castrillion, Elizabeth A. Mittendorf

المصدر: Cancer Immunology Research. 8:A81-A81

مصطلحات موضوعية: Cancer Research, Breast cancer, Immune system, business.industry, medicine.medical_treatment, Immunology, Cancer research, medicine, Immunotherapy, medicine.disease, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a2ad131c0d874d1c9fc875462ff23a9d
https://doi.org/10.1158/2326-6074.tumimm19-a81

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Abstract P5-04-01: PARP inhibition modulates the infiltration, phenotype and function of tumor-associated macrophages (TAMs) in BRCA-associated breast cancer and can be augmented by harnessing the anti-tumor potential of TAMs

المصدر: Cancer Research. 80:P5-04

مصطلحات موضوعية: Cancer Research, Tumor microenvironment, CD40, medicine.medical_treatment, Antigen presentation, Biology, Cytokine, Immune system, Oncology, PARP inhibitor, Cancer research, medicine, biology.protein, CD80, Triple-negative breast cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::01651e0159cdd196b77fab366f8d29c9
https://doi.org/10.1158/1538-7445.sabcs19-p5-04-01

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