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1
المؤلفون: Emma E. Scott, Martyn C. Coldwell, Izzy Boyfield, Christopher N. Johnson, Rachel Stacey, Graham J. Riley, Michael S. Hadley, Kevin M. Thewlis, Geoffrey Stemp
المصدر: Bioorganic & Medicinal Chemistry Letters. 7:1995-1998
مصطلحات موضوعية: Chemistry, medicine.drug_class, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, In vitro, Dopamine receptor D3, Drug Discovery, medicine, Molecular Medicine, Selectivity, Molecular Biology
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2
المؤلفون: Emma E. Scott, Geoffrey Stemp, Izzy Boyfield, Christopher N. Johnson, M. A. M. Healy, Stephen A. Smith, David John Nash, Michael S. Hadley, Graham J. Riley, Martyn C. Coldwell
المصدر: Bioorganic & Medicinal Chemistry Letters. 7:327-330
مصطلحات موضوعية: Tertiary amine, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Ligand (biochemistry), Biochemistry, Chemical synthesis, In vitro, Sulfone, chemistry.chemical_compound, Dopamine receptor D3, Drug Discovery, Benzyl group, Molecular Medicine, Selectivity, Molecular Biology
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3
المؤلفون: Geoffrey Stemp, Harry John Wadsworth, Eric Alfred Watts, Roger Edward Markwell, Stephen A. Smith, David Bolton, Martyn C. Coldwell, Izzy Boyfield, Christopher N. Johnson, Amanda Johns, Graham J. Riley, Michael S. Hadley, David John Nash, Emma E. Scott
المصدر: Bioorganic & Medicinal Chemistry Letters. 7:485-488
مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Substituent, Pharmaceutical Science, Biochemistry, Chemical synthesis, Affinities, Sulfonamide, chemistry.chemical_compound, Sulfonate, chemistry, Dopamine receptor D3, Drug Discovery, Molecular Medicine, Selectivity, Molecular Biology, Pyrrole
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4
المؤلفون: Emma E. Scott, Graham J. Riley, Izzy Boyfield, Christopher N. Johnson, Michael S. Hadley, David John Nash, Geoffrey Stemp, Martyn C. Coldwell, Stephen A. Smith, M. A. M. Healy
المصدر: ChemInform. 28
مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Dopamine receptor D3, Stereochemistry, Benzyl group, General Medicine, Selectivity, Pyrrole derivatives
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5
المؤلفون: Martyn C. Coldwell, Emma E. Scott, Christopher Norbert Johnson, Izzy Boyfield, R. Stacey, Michael Stewart Beecham Pharmaceuticals Hadley, Riley Gj, Geoffrey Stemp, Kevin M. Thewlis
المصدر: ChemInform. 28
مصطلحات موضوعية: Dopamine receptor D3, Stereochemistry, Chemistry, General Medicine, Selectivity
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6
المؤلفون: Geoffrey Stemp, Emma E. Scott, Izzy Boyfield, David John Nash, Graham J. Riley, Martyn C. Coldwell, Philip M. Jeffrey, Maureen A.M. Healy, Christopher N. Johnson, Rachel Stacey, Kim Y. Avenell, Kevin M. Thewlis, Stephen A. Smith, Michael S. Hadley
المصدر: Bioorganicmedicinal chemistry letters. 8(20)
مصطلحات موضوعية: Tetrahydronaphthalenes, medicine.drug_class, Stereochemistry, Chemistry, Metabolic Clearance Rate, Organic Chemistry, Clinical Biochemistry, Receptors, Dopamine D3, Pharmaceutical Science, Carboxamide, Ligand (biochemistry), Biochemistry, Chemical synthesis, Rats, Dopamine D2 Receptor Antagonists, In vivo, Dopamine receptor D3, Drug Discovery, medicine, Functional selectivity, Molecular Medicine, Animals, Selectivity, Chirality (chemistry), Molecular Biology
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7
المؤلفون: Stephen A. Smith, Geoffrey Stemp, Derek N. Middlemiss, Graham J. Riley, Izzy Boyfield, Maureen A.M. Healy, David G. Cooper, Ron J. King, Amanda Johns, Martyn C. Coldwell, Thomas Henry Brown, David John Nash, Jim J. Hagan, Emma E. Scott, Michael S. Hadley
المصدر: Journal of medicinal chemistry. 39(10)
مصطلحات موضوعية: Bicyclic molecule, Stereochemistry, Chemistry, Receptors, Dopamine D4, Antagonist, Esters, Naphthalenes, Chemical synthesis, Radioligand Assay, In vitro, Dopamine D2 Receptor Antagonists, Dopamine receptor, Dopamine, Drug Design, Drug Discovery, medicine, Molecular Medicine, Dopamine Antagonists, Humans, medicine.drug
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8دورية أكاديمية
المؤلفون: Miller MA; Warwick Medical School, University of Warwick, Coventry, UK michelle.miller@warwick.ac.uk., Yu LM; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Ali A; Respiratory and Sleep Sciences, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK., Apenteng P; Primary Care Clinical Sciences, University of Birmingham, Birmingham, UK., Auguste P; Warwick Medical School, University of Warwick, Coventry, UK., Dale J; Warwick Medical School, University of Warwick, Coventry, UK., Hope K; Hope2Sleep, East Yorkshire, UK., Shanyinde M; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Grabey J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Scott E; Warwick Medical School, University of Warwick, Coventry, UK., Smith A; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Cappuccio FP; Warwick Medical School, University of Warwick, Coventry, UK.; University Hospitals Coventry and Warwickshire (UHCW), Coventry, UK.
مؤلفون مشاركون: FOUND Trial study group
المصدر: BMJ open [BMJ Open] 2024 Jul 25; Vol. 14 (7), pp. e090000. Date of Electronic Publication: 2024 Jul 25.
نوع المنشور: Journal Article; Clinical Trial Protocol
بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
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9دورية أكاديمية
المؤلفون: Hodgson K; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Orozco-Moreno M; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Goode EA; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Fisher M; The Mellanby Centre for Musculoskeletal Research, Division of Clinical Medicine, The University of Sheffield, Sheffield, UK., Garnham R; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Beatson R; Centre for Inflammation and Tissue Repair, UCL Respiratory, Division of Medicine, University College London (UCL), Rayne 9 Building, London WC1E 6JF, UK., Turner H; Cellular Pathology, The Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK., Livermore K; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Zhou Y; The Mellanby Centre for Musculoskeletal Research, Division of Clinical Medicine, The University of Sheffield, Sheffield, UK., Wilson L; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Newcastle upon Tyne NE2 4HH, UK., Visser EA; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands., Pijnenborg JF; GlycoTherapeutics B.V., Nijmegen, the Netherlands., Eerden N; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands; GlycoTherapeutics B.V., Nijmegen, the Netherlands., Moons SJ; Synvenio B.V., Nijmegen, the Netherlands., Rossing E; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands., Hysenaj G; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Krishna R; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Peng Z; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Nangkana KP; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Schmidt EN; Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2E1, Canada., Duxfield A; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK; International Centre for Life, Biosciences Institute, Newcastle University, Newcastle Upon Tyne NE1 3BZ, UK., Dennis EP; International Centre for Life, Biosciences Institute, Newcastle University, Newcastle Upon Tyne NE1 3BZ, UK., Heer R; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Newcastle upon Tyne NE2 4HH, UK; Department of Urology, Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE7 7DN, UK., Lawson MA; The Mellanby Centre for Musculoskeletal Research, Division of Clinical Medicine, The University of Sheffield, Sheffield, UK., Macauley M; Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2E1, Canada., Elliott DJ; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Büll C; Biomolecular Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, the Netherlands., Scott E; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK., Boltje TJ; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands., Drake RR; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC, USA., Wang N; The Mellanby Centre for Musculoskeletal Research, Division of Clinical Medicine, The University of Sheffield, Sheffield, UK; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, LE2 7LX, UK. Electronic address: nw208@Leicester.ac.uk., Munkley J; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle upon Tyne NE1 3BZ, UK. Electronic address: Jennifer.munkley@ncl.ac.uk.
المصدر: EBioMedicine [EBioMedicine] 2024 Jun; Vol. 104, pp. 105163. Date of Electronic Publication: 2024 May 20.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
مواضيع طبية MeSH: Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/metabolism , Prostatic Neoplasms*/drug therapy , Sialyltransferases*/metabolism , Sialyltransferases*/genetics , Bone Neoplasms*/secondary , Bone Neoplasms*/metabolism , Bone Neoplasms*/drug therapy , N-Acetylneuraminic Acid*/metabolism, Male ; Humans ; Animals ; Mice ; Cell Line, Tumor ; Disease Models, Animal ; Antigens, CD/metabolism ; Polysaccharides/pharmacology ; Glycosylation ; beta-D-Galactoside alpha 2-6-Sialyltransferase
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10دورية أكاديمية
المؤلفون: Hutton E; Department of Chemistry, University of York, York, United Kingdom.; Hull York Medical School, University of York, York, United Kingdom., Scott E; Newcastle University, Centre for Cancer, Newcastle University Biosciences Institute, Newcastle, United Kingdom., Robson CN; Newcastle University, Centre for Cancer, Newcastle University Translational and Clinical Research Institute, Newcastle, United Kingdom., Signoret N; Hull York Medical School, University of York, York, United Kingdom., Fascione MA; Department of Chemistry, University of York, York, United Kingdom.
المصدر: Frontiers in molecular biosciences [Front Mol Biosci] 2024 Apr 26; Vol. 11, pp. 1390711. Date of Electronic Publication: 2024 Apr 26 (Print Publication: 2024).
نوع المنشور: Journal Article; Review
بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101653173 Publication Model: eCollection Cited Medium: Print ISSN: 2296-889X (Print) Linking ISSN: 2296889X NLM ISO Abbreviation: Front Mol Biosci Subsets: PubMed not MEDLINE