-
1
المؤلفون: Olov Wallner, Armando Cázares‐Körner, Emma Rose Scaletti, Geoffrey Masuyer, Tove Bekkhus, Torkild Visnes, Kirill Mamonov, Florian Ortis, Thomas Lundbäck, Maria Volkova, Tobias Koolmeister, Elisée Wiita, Olga Loseva, Monica Pandey, Evert Homan, Carlos Benítez‐Buelga, Jonathan Davies, Martin Scobie, Ulrika Warpman Berglund, Christina Kalderén, Pål Stenmark, Thomas Helleday, Maurice Michel
المصدر: ChemMedChem. 18
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry
-
2
المؤلفون: Daniel Rehling, Emma Rose Scaletti, Inna Rozman Grinberg, Daniel Lundin, Margareta Sahlin, Anders Hofer, Britt-Marie Sjöberg, Pål Stenmark
المصدر: Biochemistry. 61:92-106
مصطلحات موضوعية: Biochemistry and Molecular Biology, Biochemistry, Biokemi och molekylärbiologi
وصف الملف: application/pdf
-
3
المؤلفون: Olov Wallner, Armando Cázares‐Körner, Emma Rose Scaletti, Geoffrey Masuyer, Tove Bekkhus, Torkild Visnes, Kirill Mamonov, Florian Ortis, Thomas Lundbäck, Maria Volkova, Tobias Koolmeister, Elisée Wiita, Olga Loseva, Monica Pandey, Evert Homan, Carlos Benítez‐Buelga, Jonathan Davies, Martin Scobie, Ulrika Warpman Berglund, Christina Kalderén, Pål Stenmark, Thomas Helleday, Maurice Michel
المصدر: ChemMedChem
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry
وصف الملف: application/pdf
-
4
المؤلفون: Daniel, Rehling, Emma Rose, Scaletti, Inna, Rozman Grinberg, Daniel, Lundin, Margareta, Sahlin, Anders, Hofer, Britt-Marie, Sjöberg, Pål, Stenmark
المصدر: Biochemistry
مصطلحات موضوعية: Aquifex, Models, Molecular, Protein Subunits, Allosteric Regulation, Bacterial Proteins, Protein Conformation, Ribonucleotide Reductases, Protein Multimerization, Crystallography, X-Ray, Article
-
5
المؤلفون: Thomas Helleday, Evert Homan, Ann-Sofie Jemth, Maurice Michel, Emma Rose Scaletti, Pål Stenmark
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Biochemistry, Kinase, Ribavirin, RNA, Enzyme kinetics, Prodrug, Nudix hydrolase, Active metabolite, DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8afed35df562cee990fda28c09b874ca
https://doi.org/10.1101/2021.11.16.468802 -
6
المؤلفون: Chi Kong Li, Smita Bhatia, Yung-Li Yang, Wentao Yang, Pål Stenmark, Emma Rose Scaletti, James R Goodhand, Minu Singh, C. H. Li, Keito Hoshitsuki, Motohiro Kato, Takaya Moriyama, Jun J. Yang, Gareth J. Walker, Mary V. Relling, Colton Smith, Tariq Ahmad, Hiroki Hori, Wenjian Yang, Allen Eng Juh Yeoh, Prateek Bhatia, Nicholas A. Kennedy, Deepa Bhojwani, Kenneth A. Matreyek, Douglas M. Fowler, Rina Nishii, Federico Antillon Klussmann, Lie Li, Amita Trehan, Chase C. Suiter, Chris Parish, Liz Y P Yuen
المصدر: Proceedings of the National Academy of Sciences. 117:5394-5401
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Multidisciplinary, Thiopurine methyltransferase, Computational biology, Biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Toxicity, medicine, biology.protein, Medical genetics, Missense mutation, Allele, Gene, Massively parallel, Pharmacogenetics
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6f46bae116226cd42ca77248453b307c
https://doi.org/10.1073/pnas.1915680117 -
7
المؤلفون: Chase C, Suiter, Takaya, Moriyama, Kenneth A, Matreyek, Wentao, Yang, Emma Rose, Scaletti, Rina, Nishii, Wenjian, Yang, Keito, Hoshitsuki, Minu, Singh, Amita, Trehan, Chris, Parish, Colton, Smith, Lie, Li, Deepa, Bhojwani, Liz Y P, Yuen, Chi-Kong, Li, Chak-Ho, Li, Yung-Li, Yang, Gareth J, Walker, James R, Goodhand, Nicholas A, Kennedy, Federico Antillon, Klussmann, Smita, Bhatia, Mary V, Relling, Motohiro, Kato, Hiroki, Hori, Prateek, Bhatia, Tariq, Ahmad, Allen E J, Yeoh, Pål, Stenmark, Douglas M, Fowler, Jun J, Yang
المصدر: Proc Natl Acad Sci U S A
مصطلحات موضوعية: Protein Conformation, alpha-Helical, Risk, Dose-Response Relationship, Drug, Pharmacogenomic Variants, Antimetabolites, Endpoint Determination, Mercaptopurine, Mutation, Missense, Biological Sciences, HEK293 Cells, Amino Acid Substitution, Enzyme Stability, Humans, Precision Medicine, Pyrophosphatases, Alleles
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::199ea65152309dc33cccd30a4e34b1d5
https://pubmed.ncbi.nlm.nih.gov/32094176 -
8
المؤلفون: Emma Rose, Scaletti, Karl S, Vallin, Lars, Bräutigam, Antonio, Sarno, Ulrika, Warpman Berglund, Thomas, Helleday, Pål, Stenmark, Ann-Sofie, Jemth
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: crystal structure, Embryo, Nonmammalian, Nudix hydrolase 1 (NUDT1), substrate specificity, Deoxyribonucleotides, enzyme catalysis, Evolution, Molecular, Deoxyadenine Nucleotides, Catalytic Domain, enzyme kinetics, Animals, Humans, heterocyclic compounds, Editors' Picks, Pyrophosphatases, Zebrafish, X-ray crystallography, nucleotide hydrolysis, epigenetics, Hydrolysis, Phosphoric Monoester Hydrolases, Kinetics, DNA Repair Enzymes, N6-methyl-dATP, nucleoside/nucleotide metabolism, MutT homologue 1 (MTH1), methylation, hydrolase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::538019f703ff3f6c4263fec1337e83d3
https://pubmed.ncbi.nlm.nih.gov/32144205 -
9
المصدر: Journal of Biological Chemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::00204ce3bf111ab64bbfa0206c93b496
-
10
المصدر: Journal of molecular biology. 432(4)
مصطلحات موضوعية: Epigenomics, DNA damage, Molecular Sequence Data, Substrate analog, Protein Structure, Secondary, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Structural Biology, Animals, Humans, Nucleotide, DCTP pyrophosphatase 1, Epigenetics, Amino Acid Sequence, Pyrophosphatases, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, DNA replication, Cytidine, Phosphoric Monoester Hydrolases, Kinetics, Biochemistry, chemistry, Deoxycytosine Nucleotides, biology.protein, 030217 neurology & neurosurgery, DNA, DNA Damage, Protein Binding