المؤلفون: Gulay, KCM, Zhang, XL, Pantazopoulou, V, Patel, J, Esparza, E, Babu, DSP, Ogawa, S, Weitz, J, Ng, I, Mose, ES, Pu, MY, Engle, DD, Lowy, AM, Tiriac, H

المصدر: Cancer research. 83(18):3001-3012

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:153971547

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Tremblay JR; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA.; The Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA., Ortiz JA; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA.; The Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA., Quijano JC; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Zook HN; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA.; The Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA., Erdem N; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA.; The Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA., LeBon JM; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Li W; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Jou K; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Tsark W; Center for Comparative Medicine, Beckman Research Institute, City of Hope, Duarte, CA, USA., Mann JR; Center for Comparative Medicine, Beckman Research Institute, City of Hope, Duarte, CA, USA., Kozlowski MT; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA., Tirrell DA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA., Esni F; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Engle DD; Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA., Riggs AD; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Ku HT; Department of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA.; The Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA.

المصدر: Stem cells (Dayton, Ohio) [Stem Cells] 2024 Apr 15; Vol. 42 (4), pp. 385-401.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE

مواضيع طبية MeSH: Acinar Cells* , Pancreatic Ducts*, Mice ; Animals ; Pancreas ; Stem Cells ; Cell Differentiation

المؤلفون: Lumibao JC; Salk Institute for Biological Studies, La Jolla, California, USA., Okhovat SR; Salk Institute for Biological Studies, La Jolla, California, USA., Peck KL; Salk Institute for Biological Studies, La Jolla, California, USA., Lin X; Salk Institute for Biological Studies, La Jolla, California, USA., Lande K; Salk Institute for Biological Studies, La Jolla, California, USA., Yomtoubian S; Salk Institute for Biological Studies, La Jolla, California, USA., Ng I; Department of Surgery, Division of Surgical Oncology, Moores Cancer Center, and., Tiriac H; Department of Surgery, Division of Surgical Oncology, Moores Cancer Center, and., Lowy AM; Department of Surgery, Division of Surgical Oncology, Moores Cancer Center, and., Zou J; Division of Biostatistics and Bioinformatics, Herbert Wertheim School of Public Health and Human Longevity Science, UCSD, San Diego, California, USA., Engle DD; Salk Institute for Biological Studies, La Jolla, California, USA.

المصدر: JCI insight [JCI Insight] 2024 Jan 09; Vol. 9 (1). Date of Electronic Publication: 2024 Jan 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/metabolism , Carcinoma, Pancreatic Ductal*/drug therapy , Carcinoma, Pancreatic Ductal*/genetics , Carcinoma, Pancreatic Ductal*/metabolism, Humans ; Animals ; Mice ; Precision Medicine ; Extracellular Matrix ; Organoids/metabolism

المؤلفون: Liang G; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Oh TG; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.; Department of Oncology Science, OU Health Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73117, USA., Hah N; Next Generation Sequencing Core, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Tiriac H; Department of Surgery, University of California San Diego, La Jolla, CA, 92093, USA., Shi Y; Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.; Bristol Myer Squibb, 10300 Campus Point Drive, Suite 100, San Diego, CA, 92121, USA., Truitt ML; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Antal CE; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.; Department of Pharmacology, University of California San Diego, La Jolla, CA, 92093, USA., Atkins AR; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Li Y; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Fraser C; HonorHealth Scottsdale Osborn Medical Center and Shea Medical Center, Scottsdale, AZ, 85260, USA., Ng S; Molecular Medicine Division, The Translational Genomic Research Institute, Phoenix, AZ, 85004, USA., Pinto AFM; Mass Spectrometry Core, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Nelson DC; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Estepa G; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Bashi S; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Banayo E; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Dai Y; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Liddle C; Storr Liver Centre, Westmead Institute for Medical Research and Sydney Medical School, University of Sydney, Westmead Hospital, Westmead, NSW, 2145, Australia., Yu RT; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Hunter T; Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Engle DD; Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Han H; Molecular Medicine Division, The Translational Genomic Research Institute, Phoenix, AZ, 85004, USA., Von Hoff DD; HonorHealth Scottsdale Osborn Medical Center and Shea Medical Center, Scottsdale, AZ, 85260, USA.; Molecular Medicine Division, The Translational Genomic Research Institute, Phoenix, AZ, 85004, USA., Downes M; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA. downes@salk.edu., Evans RM; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA. evans@salk.edu.

المصدر: Nature communications [Nat Commun] 2023 Dec 06; Vol. 14 (1), pp. 7791. Date of Electronic Publication: 2023 Dec 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/metabolism , Carcinoma, Pancreatic Ductal*/drug therapy , Carcinoma, Pancreatic Ductal*/genetics , Carcinoma, Pancreatic Ductal*/metabolism, Animals ; Mice ; Cell Line, Tumor ; Pancreas/metabolism ; Fibroblasts/metabolism ; Carcinogenesis/pathology ; Tumor Microenvironment

المؤلفون: Antal CE; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.; Department of Pharmacology, University of California San Diego, La Jolla, CA, 92093, USA., Oh TG; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.; Department of Oncology Science, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73117, USA., Aigner S; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Luo EC; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Yee BA; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Campos T; The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK., Tiriac H; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.; Department of Surgery, Division of Surgical Oncology, University of California San Diego, La Jolla, CA, 92037, USA., Rothamel KL; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Cheng Z; Center for Epigenomics, University of California San Diego, La Jolla, CA, 92037, USA., Jiao H; Center for Epigenomics, University of California San Diego, La Jolla, CA, 92037, USA., Wang A; Center for Epigenomics, University of California San Diego, La Jolla, CA, 92037, USA., Hah N; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Lenkiewicz E; Mayo Clinic in Arizona, Scottsdale, AZ, 85259, USA., Lumibao JC; Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Truitt ML; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Estepa G; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Banayo E; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Bashi S; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Esparza E; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.; Department of Surgery, Division of Surgical Oncology, University of California San Diego, La Jolla, CA, 92037, USA., Munoz RM; Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Diedrich JK; Mass Spectrometry Core for Proteomics and Metabolomics, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Sodir NM; The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Genentech, Department of Translational Oncology, 1 DNA Way, South San Francisco, CA, 94080, USA., Mueller JR; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA., Fraser CR; HonorHealth Research Institute, Scottsdale, AZ, 85258, USA.; Scottsdale Pathology Associates, Scottsdale, AZ, 85260, USA., Borazanci E; Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA.; HonorHealth Research Institute, Scottsdale, AZ, 85258, USA., Propper D; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, USA., Von Hoff DD; Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA.; HonorHealth Research Institute, Scottsdale, AZ, 85258, USA., Liddle C; Storr Liver Centre, Westmead Institute for Medical Research and Sydney Medical School, University of Sydney, Westmead Hospital, Westmead, NSW, 2145, Australia., Yu RT; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Atkins AR; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Han H; Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Lowy AM; The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.; Department of Surgery, Division of Surgical Oncology, University of California San Diego, La Jolla, CA, 92037, USA., Barrett MT; Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA., Engle DD; Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Evan GI; The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK., Yeo GW; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA.; Sanford Stem Cell Institute, University of California San Diego, La Jolla, CA, 92037, USA., Downes M; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA. downes@salk.edu., Evans RM; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA. evans@salk.edu.

المصدر: Nature communications [Nat Commun] 2023 Sep 06; Vol. 14 (1), pp. 5195. Date of Electronic Publication: 2023 Sep 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatic Neoplasms*/genetics , Carcinoma, Pancreatic Ductal*/genetics, Male ; Animals ; Mice ; RNA ; Epigenesis, Genetic ; Regulatory Sequences, Nucleic Acid ; Methyltransferases ; RNA-Binding Proteins/genetics

المؤلفون: Lumibao JC, Okhovat SR, Peck KL, Lin X, Lande K, Zou J, Engle DD

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 09. Date of Electronic Publication: 2023 May 09.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Lumibao JC; Salk Institute for Biological Studies, La Jolla, CA., Tremblay JR; Salk Institute for Biological Studies, La Jolla, CA., Hsu J; Salk Institute for Biological Studies, La Jolla, CA., Engle DD; Salk Institute for Biological Studies, La Jolla, CA.

المصدر: The Journal of experimental medicine [J Exp Med] 2022 Jun 06; Vol. 219 (6). Date of Electronic Publication: 2022 May 06.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Pancreatic Ductal*/metabolism , Pancreatic Neoplasms*/pathology, Glycosylation ; Humans ; Polysaccharides/metabolism ; Tumor Microenvironment

المؤلفون: Dasgupta A; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE., Shukla SK; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Vernucci E; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., King RJ; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Abrego J; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Mulder SE; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE., Mullen NJ; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Graves G; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Buettner K; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Thakur R; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Murthy D; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Attri KS; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Wang D; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Chaika NV; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Pacheco CG; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Rai I; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Engle DD; Cancer Center at Cold Spring Harbor Laboratory, Cold Spring Harbor, NY., Grandgenett PM; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Punsoni M; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE., Reames BN; Department of Surgery, University of Nebraska Medical Center, Omaha, NE., Teoh-Fitzgerald M; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE., Oberley-Deegan R; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE., Yu F; Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE., Klute KA; Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE., Hollingsworth MA; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Zimmerman MC; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE., Mehla K; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE., Sadoshima J; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers University, Newark, NJ., Tuveson DA; Cancer Center at Cold Spring Harbor Laboratory, Cold Spring Harbor, NY., Singh PK; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE.; The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE.

المصدر: The Journal of experimental medicine [J Exp Med] 2020 Jul 06; Vol. 217 (7).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*/drug effects, Cachexia/*complications , Cachexia/*metabolism , NADPH Oxidase 4/*metabolism , Neoplasms/*complications , Neoplasms/*metabolism , Sirtuin 1/*metabolism, Adipose Tissue/pathology ; Animals ; Cell Line ; Cell Line, Tumor ; Disease Models, Animal ; Disease Progression ; Forkhead Transcription Factors/metabolism ; HEK293 Cells ; Humans ; Metabolome/drug effects ; Mice ; Muscle Fibers, Skeletal/drug effects ; Muscle Fibers, Skeletal/metabolism ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Muscular Atrophy/metabolism ; Muscular Atrophy/pathology ; NF-kappa B/metabolism ; Oxidation-Reduction ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Protein Stability/drug effects ; Reactive Oxygen Species/metabolism ; Resveratrol/pharmacology ; Wasting Syndrome/pathology

المؤلفون: Ponz-Sarvise M; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Corbo V; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Tiriac H; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Engle DD; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Frese KK; Cancer Research UK Manchester Institute, Manchester, United Kingdom., Oni TE; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.; Graduate Program in Molecular and Cellular Biology, Stony Brook University, Stony Brook, New York., Hwang CI; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Öhlund D; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Chio IIC; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Baker LA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Filippini D; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Wright K; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Bapiro TE; Department of Oncology, University of Cambridge, Cambridge, United Kingdom., Huang P; Merck & Co., Kenilworth, New Jersey., Smith P; IMED Biotech Unit, AstraZeneca, Cambridge, United Kingdom., Yu KH; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.; Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Medical College at Cornell University, New York, New York., Jodrell DI; Department of Oncology, University of Cambridge, Cambridge, United Kingdom.; Cancer Research UK Cambridge Institute, The University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom., Park Y; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. dtuveson@cshl.edu ypark@cshl.edu.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York., Tuveson DA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. dtuveson@cshl.edu ypark@cshl.edu.; Lustgarten Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2019 Nov 15; Vol. 25 (22), pp. 6742-6755. Date of Electronic Publication: 2019 Sep 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm* , Signal Transduction*, Antineoplastic Agents/*pharmacology , Organoids/*drug effects , Organoids/*pathology , Pancreatic Neoplasms/*metabolism , Pancreatic Neoplasms/*pathology, Animals ; Cell Line, Tumor ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Humans ; Mice ; Mice, Transgenic ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/etiology ; Phosphorylation ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/metabolism ; Tissue Culture Techniques