المؤلفون: Hong CKY; The Edison Family Center for Genome Sciences and Systems Biology, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA.; Department of Genetics, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA., Wu Y; The Edison Family Center for Genome Sciences and Systems Biology, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA.; Department of Genetics, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA., Erickson AA; The Edison Family Center for Genome Sciences and Systems Biology, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA.; Department of Genetics, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA., Li J; The Edison Family Center for Genome Sciences and Systems Biology, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA.; Department of Genetics, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA., Federico AJ; The Edison Family Center for Genome Sciences and Systems Biology, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA.; Department of Genetics, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA., Cohen BA; The Edison Family Center for Genome Sciences and Systems Biology, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA. cohen@wustl.edu.; Department of Genetics, School of Medicine, Washington University in St. Louis, Saint Louis, MO, 63110, USA. cohen@wustl.edu.

المصدر: Nature communications [Nat Commun] 2024 Sep 27; Vol. 15 (1), pp. 8350. Date of Electronic Publication: 2024 Sep 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Insulator Elements*/genetics , Enhancer Elements, Genetic*/genetics, Animals ; Genome/genetics ; Heterochromatin/genetics ; Heterochromatin/metabolism ; Genomics/methods ; Mice ; High-Throughput Nucleotide Sequencing/methods

المؤلفون: Lee AS; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. arthur.lee@childrens.harvard.edu.; Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA. arthur.lee@childrens.harvard.edu.; Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA, USA. arthur.lee@childrens.harvard.edu.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. arthur.lee@childrens.harvard.edu., Ayers LJ; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Kosicki M; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Chan WM; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Fozo LN; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Pratt BM; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Collins TE; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Zhao B; Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Rose MF; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.; Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Medical Genetics Training Program, Harvard Medical School, Boston, MA, USA., Sanchis-Juan A; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Fu JM; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Wong I; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Zhao X; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Tenney AP; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.; Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lee C; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard College, Cambridge, MA, USA., Laricchia KM; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Barry BJ; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Bradford VR; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Jurgens JA; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.; Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., England EM; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lek M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., MacArthur DG; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Centre for Population Genomics, Garvan Institute of Medical Research and UNSW Sydney, Sydney, NSW, Australia.; Centre for Population Genomics, Murdoch Children's Research Institute, Melbourne, VIC, Australia., Lee EA; Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Talkowski ME; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Brand H; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, MA, USA., Pennacchio LA; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Engle EC; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.; Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.; Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. elizabeth.engle@childrens.harvard.edu.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. elizabeth.engle@childrens.harvard.edu.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.; Medical Genetics Training Program, Harvard Medical School, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.; Department of Ophthalmology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. elizabeth.engle@childrens.harvard.edu.

المصدر: Nature communications [Nat Commun] 2024 Sep 27; Vol. 15 (1), pp. 8268. Date of Electronic Publication: 2024 Sep 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Enhancer Elements, Genetic*/genetics, Animals ; Mice ; Humans ; Motor Neurons/metabolism ; Chromatin/metabolism ; Chromatin/genetics ; Male ; Single-Cell Analysis ; Epigenomics/methods ; Female ; Pedigree

المؤلفون: Griffith EC; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., West AE; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA. Electronic address: west@neuro.duke.edu., Greenberg ME; Department of Neurobiology, Harvard Medical School, Boston, MA, USA. Electronic address: michael_greenberg@hms.harvard.edu.

المصدر: Neuron [Neuron] 2024 Sep 25; Vol. 112 (18), pp. 3043-3057. Date of Electronic Publication: 2024 Aug 28.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Neuronal Plasticity*/physiology , Neurons*/physiology , Enhancer Elements, Genetic*/genetics, Animals ; Humans ; Gene Expression Regulation ; Brain/physiology ; Nerve Net/physiology

المؤلفون: Wan M; Epigenetics and Stem Cell Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA., Liu Y; Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA., Li D; Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA., Snyder RJ; Epigenetics and Stem Cell Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA., Elkin LB; Epigenetics and Stem Cell Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA., Day CR; Epigenetics and Stem Cell Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA., Rodriguez J; Epigenetics and Stem Cell Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA., Grunseich C; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Mahley RW; Gladstone Institute of Neurological Disease, San Francisco, CA, USA.; Department of Pathology and Medicine, University of California, San Francisco, CA, USA., Watts JA; Epigenetics and Stem Cell Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA., Cheung VG; Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA.

المصدر: Nucleic acids research [Nucleic Acids Res] 2024 Sep 23; Vol. 52 (17), pp. 10235-10254.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Astrocytes*/metabolism , Microglia*/metabolism , Apolipoproteins E*/genetics , Apolipoproteins E*/metabolism , Enhancer Elements, Genetic*, Humans ; Animals ; Gene Expression Regulation ; Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; RNA, Untranslated/genetics ; RNA, Untranslated/metabolism ; Mice ; Transcription Factor AP-1/metabolism ; Transcription Factor AP-1/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Ataxia Telangiectasia Mutated Proteins/genetics ; Cells, Cultured ; Phosphorylation ; Enhancer RNAs

المؤلفون: Tsang FH; Chinese Academy of Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Oxford OX3 7BN, UK.; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Stolper RJ; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Hanifi M; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Cornell LJ; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Francis HS; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Davies B; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Oxford OX3 7BN, UK., Higgs DR; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.; Chinese Academy of Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Oxford OX3 7BN, UK., Kassouf MT; MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.

المصدر: Nucleic acids research [Nucleic Acids Res] 2024 Sep 23; Vol. 52 (17), pp. 10180-10193.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: CCCTC-Binding Factor*/metabolism , CCCTC-Binding Factor*/genetics , Enhancer Elements, Genetic* , Promoter Regions, Genetic*, Binding Sites/genetics ; Humans ; Animals ; Mice ; Repressor Proteins/metabolism ; Repressor Proteins/genetics ; Insulator Elements/genetics ; Protein Binding ; Nucleotide Motifs ; Cell Line ; Gene Expression Regulation ; Cell Differentiation/genetics

المؤلفون: Foran G; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada., Hallam RD; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada., Megaly M; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada., Turgambayeva A; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada., Antfolk D; Department of Immunology, Moffitt Cancer Centre, Tampa, FL, USA., Li Y; Department of Computer Science, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada., Luca VC; Department of Immunology, Moffitt Cancer Centre, Tampa, FL, USA., Necakov A; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada. anecakov@brocku.ca.

المصدر: Scientific reports [Sci Rep] 2024 Sep 19; Vol. 14 (1), pp. 21912. Date of Electronic Publication: 2024 Sep 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Receptor, Notch1*/metabolism , Receptor, Notch1*/genetics , Enhancer Elements, Genetic*, Humans ; Gene Expression Regulation ; Cell Nucleus/metabolism ; Phase Separation

المؤلفون: Chardon FM; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Seattle Hub for Synthetic Biology, Seattle, WA, USA., McDiarmid TA; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Seattle Hub for Synthetic Biology, Seattle, WA, USA., Page NF; Department of Psychiatry and Behavioral Sciences, Kavli Institute for Fundamental Neuroscience, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA., Daza RM; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Seattle Hub for Synthetic Biology, Seattle, WA, USA., Martin BK; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Seattle Hub for Synthetic Biology, Seattle, WA, USA., Domcke S; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Regalado SG; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Lalanne JB; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Calderon D; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Li X; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Seattle Hub for Synthetic Biology, Seattle, WA, USA., Starita LM; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA., Sanders SJ; Department of Psychiatry and Behavioral Sciences, Kavli Institute for Fundamental Neuroscience, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, OX3 7TY, UK., Ahituv N; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA. Nadav.Ahituv@ucsf.edu.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA. Nadav.Ahituv@ucsf.edu., Shendure J; Department of Genome Sciences, University of Washington, Seattle, WA, USA. shendure@uw.edu.; Seattle Hub for Synthetic Biology, Seattle, WA, USA. shendure@uw.edu.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA. shendure@uw.edu.; Howard Hughes Medical Institute, Seattle, WA, USA. shendure@uw.edu.; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA. shendure@uw.edu.

المصدر: Nature communications [Nat Commun] 2024 Sep 18; Vol. 15 (1), pp. 8209. Date of Electronic Publication: 2024 Sep 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Single-Cell Analysis*/methods , CRISPR-Cas Systems* , Enhancer Elements, Genetic*/genetics, Humans ; K562 Cells ; Promoter Regions, Genetic/genetics ; RNA, Guide, CRISPR-Cas Systems/genetics ; Autism Spectrum Disorder/genetics ; Neurons/metabolism ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/cytology ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics

المؤلفون: Martin CC; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Oeser JK; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Wangmo T; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Flemming BP; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Attie AD; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Department of Medicine, University of Wisconsin-Madison, Wisconsin, USA., Keller MP; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA., O'Brien RM; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

المصدر: Journal of molecular endocrinology [J Mol Endocrinol] 2024 Sep 18; Vol. 73 (3). Date of Electronic Publication: 2024 Sep 18 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioScientifica Country of Publication: England NLM ID: 8902617 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1479-6813 (Electronic) Linking ISSN: 09525041 NLM ISO Abbreviation: J Mol Endocrinol Subsets: MEDLINE

مواضيع طبية MeSH: Promoter Regions, Genetic*/genetics , Glucose-6-Phosphatase*/genetics , Glucose-6-Phosphatase*/metabolism , Glucagon-Secreting Cells*/metabolism , Enhancer Elements, Genetic*, Animals ; Humans ; Mice ; Insulin-Secreting Cells/metabolism ; Gene Expression Regulation ; Cell Line

المؤلفون: Perlman BS; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, USA.; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, USA.; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, USA., Burget N; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, USA.; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, USA.; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, USA., Zhou Y; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, USA.; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, USA.; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, USA., Schwartz GW; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Petrovic J; Department of Proteomic and Genomic Technologies, Genentech, South San Francisco, USA., Modrusan Z; Department of Proteomic and Genomic Technologies, Genentech, South San Francisco, USA., Faryabi RB; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, USA. faryabi@pennmedicine.upenn.edu.; Penn Epigenetics Institute, University of Pennsylvania, Philadelphia, USA. faryabi@pennmedicine.upenn.edu.; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, USA. faryabi@pennmedicine.upenn.edu.

المصدر: Nature communications [Nat Commun] 2024 Sep 14; Vol. 15 (1), pp. 8070. Date of Electronic Publication: 2024 Sep 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Promoter Regions, Genetic*/genetics , Enhancer Elements, Genetic*/genetics , Drug Resistance, Neoplasm*/genetics , Gene Regulatory Networks* , Carcinogenesis*/genetics , Gene Expression Regulation, Neoplastic*, Humans ; Female ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Oncogenes/genetics ; Cell Line, Tumor ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Leukemia/genetics ; Leukemia/metabolism ; Lymphoma/genetics ; Lymphoma/metabolism

المؤلفون: Jankowski J; Section of Genetics and Physiology, Laboratory of Cellular and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD, 20892, USA. jakub.jankowski@nih.gov.; 8 Center Drive, Room 107, 20892, Bethesda, MD, USA. jakub.jankowski@nih.gov., Lee HK; Section of Genetics and Physiology, Laboratory of Cellular and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD, 20892, USA., Liu C; Transgenic Core, National Heart, Lung, and Blood Institute, US National Institutes of Health, Bethesda, MD, 20892, USA., Wilflingseder J; Department of Physiology and Pathophysiology, University of Veterinary Medicine Vienna, 1210, Vienna, Austria., Hennighausen L; Section of Genetics and Physiology, Laboratory of Cellular and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD, 20892, USA.

المصدر: Communications biology [Commun Biol] 2024 Sep 14; Vol. 7 (1), pp. 1142. Date of Electronic Publication: 2024 Sep 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

مواضيع طبية MeSH: Klotho Proteins*/metabolism , Kidney*/metabolism , Glucuronidase*/genetics , Glucuronidase*/metabolism , Enhancer Elements, Genetic* , Sex Characteristics* , Hepatocyte Nuclear Factor 1-beta*/genetics , Hepatocyte Nuclear Factor 1-beta*/metabolism, Animals ; Mice ; Male ; Female ; Mice, Knockout ; Gene Expression Regulation ; Mice, Inbred C57BL