المؤلفون: Pavel FBA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN, USA., Palmer GE; Department of Clinical Pharmacy and Translational Sciences, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, TN, USA., Hevener KE; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN, USA. Electronic address: khevener@uthsc.edu.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Apr 23; Vol. 705, pp. 149740. Date of Electronic Publication: 2024 Feb 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)*/genetics , Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)*/metabolism , Clostridioides difficile*/metabolism, Base Composition ; Phylogeny ; RNA, Ribosomal, 16S ; Sequence Analysis, DNA ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry

المؤلفون: Biswas S; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT-DU), Bhubaneswar, 751024, India., Patra A; Transcription Regulation Group, International Centre of Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, 110067, India., Paul P; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT-DU), Bhubaneswar, 751024, India.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Misra N; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT-DU), Bhubaneswar, 751024, India.; KIIT-Technology Business Incubator, Kalinga Institute of Industrial Technology (KIIT-DU), Bhubaneswar, 751024, India., Kushwaha GS; Transcription Regulation Group, International Centre of Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, 110067, India. gajrajsk@gmail.com.; KIIT-Technology Business Incubator, Kalinga Institute of Industrial Technology (KIIT-DU), Bhubaneswar, 751024, India. gajrajsk@gmail.com., Suar M; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT-DU), Bhubaneswar, 751024, India. msuar@kiitbiotech.ac.in.; KIIT-Technology Business Incubator, Kalinga Institute of Industrial Technology (KIIT-DU), Bhubaneswar, 751024, India. msuar@kiitbiotech.ac.in.

المصدر: The protein journal [Protein J] 2024 Feb; Vol. 43 (1), pp. 84-95. Date of Electronic Publication: 2023 Dec 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 101212092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8355 (Electronic) Linking ISSN: 15723887 NLM ISO Abbreviation: Protein J Subsets: MEDLINE

مواضيع طبية MeSH: Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)*/chemistry , Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)*/metabolism , Klebsiella pneumoniae*, NAD/metabolism ; Binding Sites ; Anti-Bacterial Agents

المؤلفون: Junior DBC; Programa de pós-graduação em Biotecnologia, Universidade Estadual de Feira de Santana, Brazil., Lacerda PS; Laboratório de Bioinformática e Modelagem Molecular, Universidade Federal da Bahia, Brazil., de Pilla Varotti F; Programa de pós-graduação em Biotecnologia, Universidade Federal de São João Del-Rei, Brazil., Leite FHA; Programa de pós-graduação em Biotecnologia, Universidade Estadual de Feira de Santana, Brazil; Programa de pós-graduação em Ciências Farmacêuticas, Universidade Estadual de Feira de Santana, Brazil; Laboratório de Modelagem Molecular, Universidade Estadual de Feira de Santana, Brazil. Electronic address: fhenrique@uefs.br.

المصدر: Computational biology and chemistry [Comput Biol Chem] 2024 Aug; Vol. 111, pp. 108093. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials*/pharmacology , Antimalarials*/chemistry , Plasmodium falciparum*/drug effects , Plasmodium falciparum*/enzymology , Molecular Dynamics Simulation*, Parasitic Sensitivity Tests ; Molecular Structure ; Humans ; Drug Development ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/antagonists & inhibitors ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/metabolism ; Nitrofurantoin/chemistry ; Nitrofurantoin/pharmacology ; Structure-Activity Relationship

المؤلفون: Li F; Hubei Key Laboratory of Quality Control of Characteristic Fruits and Vegetables/College of Life Science and Technology, Hubei Engineering University, Xiaogan 432000, China., Deng J; Hubei Key Laboratory of Quality Control of Characteristic Fruits and Vegetables/College of Life Science and Technology, Hubei Engineering University, Xiaogan 432000, China., Zhang Z; Hubei Key Laboratory of Quality Control of Characteristic Fruits and Vegetables/College of Life Science and Technology, Hubei Engineering University, Xiaogan 432000, China., Wang C; Hubei Key Laboratory of Quality Control of Characteristic Fruits and Vegetables/College of Life Science and Technology, Hubei Engineering University, Xiaogan 432000, China., Mao Y; Hubei Key Laboratory of Quality Control of Characteristic Fruits and Vegetables/College of Life Science and Technology, Hubei Engineering University, Xiaogan 432000, China.

المصدر: Phytopathology [Phytopathology] 2024 Apr; Vol. 114 (4), pp. 780-791. Date of Electronic Publication: 2024 Apr 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Phytopathological Society] Country of Publication: United States NLM ID: 9427222 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0031-949X (Print) Linking ISSN: 0031949X NLM ISO Abbreviation: Phytopathology Subsets: MEDLINE

مواضيع طبية MeSH: Xanthomonas*/genetics , Xanthomonas*/drug effects , Triclosan*/pharmacology , Plant Diseases*/microbiology , Juglans*/microbiology , Bacterial Proteins*/genetics , Bacterial Proteins*/metabolism, Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/genetics ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/metabolism ; Fatty Acids/metabolism ; Drug Resistance, Bacterial/genetics ; Escherichia coli/genetics

المؤلفون: Joaquim AR; Pharmaceutical Synthesis Group (PHARSG), Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil; Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil; Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Santa Maria, RS 97105-900, Brazil. Electronic address: angelica.joaquim@ufsm.br., Lopes MS; Pharmaceutical Synthesis Group (PHARSG), Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil; Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil., Fortes IS; Pharmaceutical Synthesis Group (PHARSG), Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil; Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil., de Bem Gentz C; Pharmaceutical Synthesis Group (PHARSG), Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil; Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil; Programa de Pós-graduação em Microbiologia Agrícola e do Ambiente, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90035-003, Brazil., de Matos Czeczot A; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil., Perelló MA; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil., Roth CD; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil., Vainstein MH; Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 91501-970, Brazil., Basso LA; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil., Bizarro CV; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil., Machado P; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS 90619-900, Brazil. Electronic address: pablo.machado@pucrs.br., de Andrade SF; Pharmaceutical Synthesis Group (PHARSG), Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil; Programa de Pós-graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil; Programa de Pós-graduação em Microbiologia Agrícola e do Ambiente, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90035-003, Brazil. Electronic address: saulo.fernandes@ufrgs.br.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Oct; Vol. 151, pp. 107705. Date of Electronic Publication: 2024 Aug 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Mycobacterium tuberculosis*/drug effects , Mycobacterium tuberculosis*/enzymology , Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemistry , Antitubercular Agents*/chemical synthesis , Microbial Sensitivity Tests* , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/chemical synthesis , Oxyquinoline*/chemistry , Oxyquinoline*/pharmacology, Structure-Activity Relationship ; Molecular Structure ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/antagonists & inhibitors ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/metabolism ; Dose-Response Relationship, Drug

المؤلفون: Zhang L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Yang J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Xu X; Editorial Office of Chinese Journal of Medical Genetics, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, China., Zhang J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Qiu Z; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Ju Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Luo B; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Liu Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Gou X; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Sui J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Chen B; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China., Wang Y; Institute of traditional Chinese medicine, Sichuan College of Traditional Chinese Medicine, The Second Hospital of Traditional Chinese Medicine in Sichuan Province, Chengdu 610041, China., Tao T; Institute of traditional Chinese medicine, Sichuan College of Traditional Chinese Medicine, The Second Hospital of Traditional Chinese Medicine in Sichuan Province, Chengdu 610041, China., He L; Institute of traditional Chinese medicine, Sichuan College of Traditional Chinese Medicine, The Second Hospital of Traditional Chinese Medicine in Sichuan Province, Chengdu 610041, China., Yang T; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.; Laboratory of Human Diseases and Immunotherapies, West China Hospital, Sichuan University, Chengdu 610041, China.; Institute of Immunology and Inflammation, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China., Luo Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Jun 27; Vol. 67 (12), pp. 10096-10134. Date of Electronic Publication: 2024 Jun 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Methicillin-Resistant Staphylococcus aureus*/drug effects , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/therapeutic use , Anti-Bacterial Agents*/chemical synthesis , Microbial Sensitivity Tests* , Staphylococcal Infections*/drug therapy , Staphylococcal Infections*/microbiology , Drug Discovery*, Animals ; Humans ; Structure-Activity Relationship ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/antagonists & inhibitors ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/metabolism ; Mice ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/therapeutic use ; Enzyme Inhibitors/chemical synthesis

المؤلفون: Mahnashi MH; Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, Najran, Saudi Arabia., Avunoori S; Department of Pharmaceutical Chemistry, Novel Drug Design and Discovery Laboratory, SET's College of Pharmacy, Sangolli Rayanna Nagar, Dharwad, Karnataka, India., Gopi S; Department of Pharmaceutical Chemistry, Novel Drug Design and Discovery Laboratory, SET's College of Pharmacy, Sangolli Rayanna Nagar, Dharwad, Karnataka, India., Shaikh IA; Department of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia., Saif A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia., Bantun F; Faculty of Medicine, Department of Microbiology, Umm Al-Qura University, Makkah, Saudi Arabia., Faidah HS; Faculty of Medicine, Department of Microbiology, Umm Al-Qura University, Holy Makkah, Kingdom of Saudi Arabia., Alhadi AA; Faculty of Medicine, Department of Microbiology, Umm Al-Qura University, Holy Makkah, Kingdom of Saudi Arabia., Alshehri JH; Microbiology Section Pathology and Laboratory Medicine, Armed Forces Hospital Southern Region, Khamis Mushait, Kingdom of Saudi Arabia., Alharbi AA; Microbiology Section Pathology and Laboratory Medicine, Armed Forces Hospital Southern Region, Khamis Mushait, Kingdom of Saudi Arabia., S R PK; Department of Pharmaceutical Chemistry, MVM College of Pharmacy, Yelahanka, Bengaluru, Karnataka, India., Joshi SD; Department of Pharmaceutical Chemistry, Novel Drug Design and Discovery Laboratory, SET's College of Pharmacy, Sangolli Rayanna Nagar, Dharwad, Karnataka, India.

المصدر: PloS one [PLoS One] 2024 May 13; Vol. 19 (5), pp. e0303173. Date of Electronic Publication: 2024 May 13 (Print Publication: 2024).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemistry , Antitubercular Agents*/chemical synthesis , Pyrroles*/chemical synthesis , Pyrroles*/chemistry , Pyrroles*/pharmacology , Tetrahydrofolate Dehydrogenase*/metabolism , Tetrahydrofolate Dehydrogenase*/chemistry, Humans ; Catalytic Domain ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/antagonists & inhibitors ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/metabolism ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/chemistry ; Folic Acid Antagonists/pharmacology ; Folic Acid Antagonists/chemistry ; Folic Acid Antagonists/chemical synthesis ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/enzymology ; Structure-Activity Relationship

المؤلفون: Rutherford JT; Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Department of Translational Medical Sciences, Texas A&M Health Science Center, Houston, Texas 77030, United States., Avad K; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States., Dureja C; Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Department of Translational Medical Sciences, Texas A&M Health Science Center, Houston, Texas 77030, United States., Norseeda K; Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, Hawaii 96720, United States., Gc B; Department of Microbiology & Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas 77030, United States., Wu C; Department of Microbiology & Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas 77030, United States., Sun D; Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, Hawaii 96720, United States., Hevener KE; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States., Hurdle JG; Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Department of Translational Medical Sciences, Texas A&M Health Science Center, Houston, Texas 77030, United States.

المصدر: ACS infectious diseases [ACS Infect Dis] 2024 May 10; Vol. 10 (5), pp. 1612-1623. Date of Electronic Publication: 2024 Apr 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Fusobacterium nucleatum*/enzymology , Fusobacterium nucleatum*/drug effects , Fusobacterium nucleatum*/genetics , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry, Humans ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/genetics ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/antagonists & inhibitors ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/metabolism ; Microbial Sensitivity Tests ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Bacterial Proteins/antagonists & inhibitors ; Fatty Acids/chemistry ; Fusobacterium Infections/microbiology ; Fusobacterium Infections/drug therapy ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/chemistry

المؤلفون: Norseeda K; Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, HI 96720, United States., Bin Aziz Pavel F; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, United States., Rutherford JT; Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX 77030, United States., Meer HN; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, United States., Dureja C; Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX 77030, United States., Hurdle JG; Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX 77030, United States., Hevener KE; Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, United States. Electronic address: khevener@uthsc.edu., Sun D; Department of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, HI 96720, United States. Electronic address: dianqing@hawaii.edu.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Jun 06; Vol. 88-89, pp. 117330. Date of Electronic Publication: 2023 May 16.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)* , Urea*/pharmacology, Anti-Bacterial Agents/chemistry ; Structure-Activity Relationship

المؤلفون: Hasan S; College of Pharmacy, Al Ain University, Abu Dhabi 64141, United Arab Emirates., Kayed K; College of Pharmacy, Al Ain University, Abu Dhabi 64141, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi 64141, United Arab Emirates., Ghemrawi R; College of Pharmacy, Al Ain University, Abu Dhabi 64141, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi 64141, United Arab Emirates., Bataineh NA; College of Pharmacy, Al Ain University, Abu Dhabi 64141, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi 64141, United Arab Emirates., Mahgoub RE; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi 64141, United Arab Emirates., Audeh R; College of Pharmacy, Al Ain University, Abu Dhabi 64141, United Arab Emirates., Aldulaymi R; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi 64141, United Arab Emirates., Atatreh N; College of Pharmacy, Al Ain University, Abu Dhabi 64141, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi 64141, United Arab Emirates., Ghattas MA; College of Pharmacy, Al Ain University, Abu Dhabi 64141, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi 64141, United Arab Emirates.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2023 Mar 28; Vol. 28 (7). Date of Electronic Publication: 2023 Mar 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)*/metabolism, Gram-Negative Bacteria/metabolism ; Enzyme Inhibitors/pharmacology ; Gram-Positive Bacteria/metabolism ; Bacteria/metabolism ; Molecular Dynamics Simulation