نتائج البحث - "Enzyme Inhibitors -- pharmacology"

1

دورية أكاديمية

Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism.

المؤلفون: Sander, Kerstin, Gendron, Thibault, Cybulska, Klaudia A, Sirindil, Fatih, Zhou, Junhua, Kalber, Tammy L, Lythgoe, Mark F, Kurzawinski, Tom R, Brown, Morris J, Williams, Bryan, Årstad, Erik

المصدر: Journal of Medicinal Chemistry, 64 (13), 9321 - 9329 (2021-07-08)

مصطلحات موضوعية: Fluorine Radioisotopes, Fluorine-18, Cytochrome P-450 CYP11B2/analysis, Cytochrome P-450 CYP11B2/antagonists & inhibitors, Cytochrome P-450 CYP11B2/metabolism, Cytochrome P-450 Enzyme Inhibitors/chemical synthesis, Cytochrome P-450 Enzyme Inhibitors/chemistry, Cytochrome P-450 Enzyme Inhibitors/pharmacology, Hyperaldosteronism/diagnostic imaging, Hyperaldosteronism/drug therapy, Hyperaldosteronism/metabolism, Structure-Activity Relationship, Drug Development, Positron-Emission Tomography, Hyperaldosteronism, Molecular Medicine, Drug Discovery, Radiochemistry, Physical, chemical, mathematical & earth Sciences, Chemistry, Human health sciences, Endocrinology, metabolism & nutrition, Radiology, nuclear medicine & imaging, Physique, chimie, mathématiques & sciences de la terre, Chimie, Sciences de la santé humaine, Endocrinologie, métabolisme & nutrition, Radiologie, médecine & imagerie nucléaire

Relation: info:eu-repo/grantAgreement/EC/FP7/602102; https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00539; urn:issn:0022-2623; urn:issn:1520-4804

URL الوصول: https://orbi.uliege.be/handle/2268/296923

2

دورية أكاديمية

ATP-induced CA2+-signaling enhances rat gastric microvascular endothelial cell migration.

المؤلفون: Ehring, G R, Szabó, I L, Jones, M K, Sarfeh, I J, Tarnawski, A S

المصدر: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 51(4)

مصطلحات موضوعية: Adenosine Triphosphate: pharmacology, Animals, Calcium: metabolism, Calcium Signaling: drug effects, physiology, Cell Movement: drug effects, physiology, Cells, Cultured, Endothelium, Vascular: cytology, injuries, physiology, Enzyme Inhibitors: pharmacology, Intracellular Membranes: metabolism, Microcirculation, Purinergic Antagonists, Rats, Stomach: blood supply, Suramin: pharmacology, Thapsigargin: pharmacology, Wound Healing: physiology, Wounds and Injuries: physiopathology, gastric endothelial cells, ATP, calcium signaling, suramin wound repair, angiogenesisfibroblast growth-factor, mast-cells, angiogenesis, adenosine, suramin, receptors, expression, proliferation, purinoceptors, heterogeneity, Adenosine Triphosphate: pharmacology, Animals, Calcium: metabolism, Calcium Signaling: drug effects, physiology, Cell Movement: drug effects, physiology, Cells, Cultured, Endothelium, Vascular: cytology, injuries, physiology, Enzyme Inhibitors: pharmacology, Intracellular Membranes: metabolism, Microcirculation, Purinergic Antagonists, Rats, Stomach: blood supply, Suramin: pharmacology, Thapsigargin: pharmacology, Wound Healing: physiology, Wounds and Injuries: physiopathology, gastric endothelial cells, ATP, calcium signaling, suramin wound repair, angiogenesisfibroblast growth-factor, mast-cells, angiogenesis, adenosine, suramin, receptors, expression, proliferation, purinoceptors, heterogeneity

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/06f795ks

3

دورية أكاديمية

nAChR-mediated calcium responses and plasticity in Drosophila Kenyon cells.

المؤلفون: Campusano, Jorge M, Su, Hailing, Jiang, Shaojuan A, Sicaeros, Beatriz, O'Dowd, Diane K

المصدر: Developmental neurobiology. 67(11)

مصطلحات موضوعية: Animals, Bungarotoxins: pharmacology, Calcium: metabolism, Calcium Channels: drug effects, metabolism, Calcium Signaling: drug effects, physiology, Cells, Cultured, Drosophila: metabolism, Enzyme Inhibitors: pharmacology, Female, Male, Mushroom Bodies: cytology, drug effects, metabolism, Neural Pathways: drug effects, metabolism, Neuronal Plasticity: drug effects, physiology, Neurons: drug effects, metabolism, Nicotinic Agonists: pharmacology, Receptors, Nicotinic: drug effects, metabolism, Synaptic Transmission: drug effects, physiology, Thapsigargin: pharmacology, Calcium imaging, Kenyon cells, Mushroom bodies, nAChR, Nicotinealpha bungarotoxin, calcium, cyclic AMP, green fluorescent protein, nicotine, nicotinic receptor, thapsigargin, voltage gated calcium channel, animal cell, animal tissue, article, calcium cell level, calcium transport, cell population, controlled study, Drosophila, evoked response, female, male, mushroom body, nerve cell plasticity, nonhuman, priority journal, protein expression, protein synthesis, receptor upregulation, signal transduction, synaptic transmission, Animals, Bungarotoxins, Calcium, Calcium Channels, Calcium Signaling, Cells, Cultured, Drosophila, Enzyme Inhibitors, Female, Male, Mushroom Bodies, Neural Pathways, Neuronal Plasticity, Neurons, Nicotinic Agonists, Receptors, Nicotinic, Synaptic Transmission, Thapsigargin

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0ff2033q

4

تسجيل فيديو

Enzymology in drug discovery: part 2 of 2
Enzymology in drug discovery part, part 2 of 2

المؤلفون: Copeland, Robert Allen.

مصطلحات موضوعية: Drugs -- Design., Enzyme inhibitors -- Structure-activity relationships., Enzyme inhibitors -- Therapeutic use., Enzymes., Enzymology., Pharmaceutical chemistry., Drug Design., Drug Discovery., Enzyme Inhibitors -- chemistry., Enzyme Inhibitors -- metabolism., Enzyme Inhibitors -- pharmacology., Enzyme Inhibitors -- therapeutic use.

5

تسجيل فيديو

Enzymology in drug discovery: part 1 of 2
Enzymology in drug discovery, part 1 of 2

المؤلفون: Copeland, Robert Allen.

مصطلحات موضوعية: Drugs -- Design., Enzyme inhibitors -- Structure-activity relationships., Enzyme inhibitors -- Therapeutic use., Enzymes., Enzymology., Pharmaceutical chemistry., Drug Design., Drug Discovery., Enzyme Inhibitors -- chemistry., Enzyme Inhibitors -- metabolism., Enzyme Inhibitors -- pharmacology., Enzyme Inhibitors -- therapeutic use., Enzymes -- metabolism.

6

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with Covid-19. A randomized clinical trial

المؤلفون: Lawler, P.R., Derde, L.P.G., Veerdonk, F.L. van de, McVerry, B.J., Huang, D.T., Berry, L.R., Lorenzi, E., Kimmenade, R.R.J. van, Gommans, F., Vaduganathan, M., Leaf, D.E., Baron, R.M., Kim, E.Y., Frankfurter, C., Epelman, S., Kwan, Y., Grieve, R., O'Neill, S., Sadique, Z., Puskarich, M., Marshall, J.C., Higgins, A.M., Mouncey, P.R., Rowan, K.M., Al-Beidh, F., Annane, D., Arabi, Y.M., Au, C., Beane, A., Bentum-Puijk, W. van, Bonten, M.J.M., Bradbury, C.A., Brunkhorst, F.M., Burrell, A., Buzgau, A., Buxton, M., Cecconi, M., Cheng, A.C., Cove, M., Detry, M.A., Estcourt, L.J., Ezekowitz, J., Fitzgerald, M., Gattas, D., Godoy, L.C., Goossens, H., Haniffa, R., Harrison, D.A., Hills, T., Horvat, C.M., Ichihara, N., Lamontagne, F., Linstrum, K.M., McAuley, D.F., McGlothlin, A., McGuinness, S.P., McQuilten, Z., Murthy, S., Nichol, A.D., Owen, D.R.J., Parke, R.L., Parker, J.C., Pollock, K.M., Reyes, L.F., Saito, H., Santos, M.S., Saunders, C.T., Seymour, C.W., Shankar-Hari, M., Singh, V., Turgeon, A.F., Turner, A.M., Zarychanski, R., Green, C., Lewis, R.J., Angus, D.C., Berry, S., Gordon, A.C., McArthur, C.J., Webb, S.A.

المصدر: Lawler, P R, Derde, L P G, Van De Veerdonk, F L, McVerry, B J, Huang, D T, Berry, L R, Lorenzi, E, Van Kimmenade, R, Gommans, F, Vaduganathan, M, Leaf, D E, Baron, R M, Kim, E Y, Frankfurter, C, Epelmaņ, S, Kwan, Y, Grieve, R, O'Neill, S, Sadique, Z, Puskarich, M, Marshall, J C, Higgins, A M, Mouncey, P R, Rowan, K M, Al-Beidh, F, Annane, D, Arabi, Y M, Au, C, Beane, A, Van Bentum-Puijk, W, Bonten, M J M, Bradbury, C A, Brunkhorst, F M, Burrell, A, Buzgau, A, Buxton, M, Cecconi, M, Cheng, A C, Cove, M, Detry, M A, Estcourt, L J, Ezekowitz, J, Fitzgerald, M, Gattas, D, Godoy, L C, Goossens, H, Haniffa, R, Harrison, D A, Hills, T, Horvat, C M, Ichihara, N, Lamontagne, F, Linstrum, K M, McAuley, D F, McGlothlin, A, McGuinness, S P, McQuilten, Z, Murthy, S, Nichol, A D, Owen, D R J, Parke, R L, Parker, J C, Pollock, K M, Reyes, L F, Saito, H, Santos, M S, Saunders, C T, Seymour, C W, Shankar-Hari, M, Singh, V, Turgeon, A F, Turner, A M, Zarychanski, R, Green, C, Lewis, R J, Angus, D C, Berry, S, Gordon, A C, McArthur, C J & Webb, S A 2023, ' Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with Covid-19. A randomized clinical trial ', JAMA, vol. 329, no. 14, pp. 1183-1196 . https://doi.org/10.1001/jama.2023.4480
Jama : Journal of the American Medical Association, 329, 14, pp. 1183-1196
Jama : Journal of the American Medical Association, 329, 1183-1196

مصطلحات موضوعية: Male, Medicine(all), Critical Illness, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Angiotensin Receptor Antagonists/pharmacology, Angiotensin-Converting Enzyme Inhibitors/pharmacology, Bayes Theorem, COVID-19 Drug Treatment/methods, Middle Aged, Receptors, Chemokine/antagonists & inhibitors, Hospitalization, All institutes and research themes of the Radboud University Medical Center, Renin-Angiotensin System/drug effects, Humans, Female, COVID-19/therapy