المؤلفون: Saskia Carstensen, Christina Gress, Veit J. Erpenbeck, Shamsah D. Kazani, Jens M. Hohlfeld, David A. Sandham, Meike Müller

المصدر: Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Eosinophil shape change, Type 2 innate lymphocyte cells, Asthma, PGD2, DP2, CRTH2, Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1465-993X

URL الوصول: https://doaj.org/article/9ef12645bb7e4800853ed9a7b72fc9b0

المؤلفون: Carstensen, Saskia, Gress, Christina, Erpenbeck, Veit J., Kazani, Shamsah D., Hohlfeld, Jens M.^{Aff1, Aff4, Aff5}, Sandham, David A., Müller, Meike^Aff1

المصدر: Respiratory Research. 22(1)

المؤلفون: Jens M. Hohlfeld, Christina Gress, Saskia Carstensen, Shamsah Kazani, David Andrew Sandham, Veit J. Erpenbeck, Meike Müller

المصدر: Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Adult, Male, CRTH2, Adolescent, Prostaglandin Antagonists, Pyridines, medicine.medical_treatment, Receptors, Prostaglandin, Fevipiprant, Eosinophil shape change, Pharmacology, Diseases of the respiratory system, Young Adult, chemistry.chemical_compound, Type 2 innate lymphocyte cells, Cell Movement, 13,14-Dihydro-15-keto-PGD2, Eosinophil activation, medicine, PGD2 metabolites, Humans, PGD2, DP2, Lymphocytes, Receptors, Immunologic, Cell Shape, Cells, Cultured, Aged, Prostaglandin D2 receptor, Interleukin-13, RC705-779, Indoleacetic Acids, Prostaglandin D2, Research, Innate lymphoid cell, Middle Aged, Eosinophil, Asthma, Eosinophils, Cytokine, medicine.anatomical_structure, chemistry, lipids (amino acids, peptides, and proteins), Female, Cytokine secretion, Interleukin-5, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410ce53ce5849a40cfb9871315b76c80
https://doi.org/10.1186/s12931-021-01852-3

المؤلفون: Ruediger Koenen, Philipp Badorrek, Meike Mueller, Anna Pivovarova, Jens M. Hohlfeld, Norbert Krug, Abhya Gupta, Chester C. Wood, James Hilbert, Kristiane Wetzel

المساهمون: Publica

مصطلحات موضوعية: Male, AUC, CRTH2, environmental challenge chamber, medicine.medical_treatment, Receptors, Prostaglandin, adverse event, FSC, Chemoattractant receptor homologous molecule on T(H)2 cells, medicine.disease_cause, Gastroenterology, Leukocyte Count, Allergen, Anti-Allergic Agents, hay fever, Immunology and Allergy, Receptors, Immunologic, forward scatter, Cross-Over Studies, Area under the curve, Middle Aged, medicine.anatomical_structure, Treatment Outcome, Benzamides, Cytokines, Pollen, PGD(2), Female, medicine.drug, SAR, Adult, medicine.medical_specialty, area under the curve, Immunology, Seasonal allergic rhinitis, ESC, mixed-model repeated measure, Total nasal symptom score, Placebo, Poaceae, Fluticasone propionate, MMRM, Double-Blind Method, prostaglandin D(2), Internal medicine, FP, medicine, Humans, ECC, TNSS, Montelukast, eosinophil shape change, BI 671800, business.industry, fluticasone propionate, Antagonist, Rhinitis, Allergic, Seasonal, AE, Eosinophil, Allergens, Eosinophils, Nasal Mucosa, Pyrimidines, Nasal spray, inflammation, business, AR

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc85b764ea0c17fe50576730942a7aa
https://publica.fraunhofer.de/handle/publica/235385

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المؤلفون: Krug N; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany. Electronic address: norbert.krug@item.fraunhofer.de., Gupta A; Boehringer Ingelheim, Biberach, Germany., Badorrek P; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany., Koenen R; Boehringer Ingelheim, Biberach, Germany., Mueller M; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany., Pivovarova A; Boehringer Ingelheim, Biberach, Germany., Hilbert J; Boehringer Ingelheim Pharmaceuticals, Ridgefield, Conn., Wetzel K; Boehringer Ingelheim, Biberach, Germany., Hohlfeld JM; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany., Wood C; Boehringer Ingelheim Pharmaceuticals, Ridgefield, Conn.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2014 Feb; Vol. 133 (2), pp. 414-9. Date of Electronic Publication: 2013 Dec 09.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Allergic Agents/*therapeutic use , Benzamides/*therapeutic use , Pyrimidines/*therapeutic use , Receptors, Immunologic/*antagonists & inhibitors , Receptors, Prostaglandin/*antagonists & inhibitors , Rhinitis, Allergic, Seasonal/*drug therapy, Adult ; Allergens/immunology ; Anti-Allergic Agents/pharmacology ; Benzamides/pharmacology ; Cross-Over Studies ; Cytokines/immunology ; Double-Blind Method ; Eosinophils/cytology ; Female ; Humans ; Leukocyte Count ; Male ; Middle Aged ; Nasal Mucosa/cytology ; Nasal Mucosa/immunology ; Poaceae/immunology ; Pollen/immunology ; Pyrimidines/pharmacology ; Receptors, Immunologic/immunology ; Receptors, Prostaglandin/immunology ; Rhinitis, Allergic, Seasonal/immunology ; Treatment Outcome