المؤلفون: Zhen C; Department of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.1239 Siping Road, Shanghai, 200092, China., Wang L; Department of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.1239 Siping Road, Shanghai, 200092, China., Feng Y; Department of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.1239 Siping Road, Shanghai, 200092, China., Whiteway M; Department of Biology, Concordia University, Montreal, QC, H4B 1R6, Canada., Hang S; Department of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.1239 Siping Road, Shanghai, 200092, China., Yu J; Department of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.1239 Siping Road, Shanghai, 200092, China., Lu H; Department of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.1239 Siping Road, Shanghai, 200092, China., Jiang Y; Department of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.1239 Siping Road, Shanghai, 200092, China.

المصدر: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Sep; Vol. 11 (35), pp. e2406473. Date of Electronic Publication: 2024 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

مواضيع طبية MeSH: Antifungal Agents*/pharmacology , Ergosterol*/metabolism , Ergosterol*/pharmacology , Autophagy*/drug effects , Candida albicans*/drug effects , Cell Membrane*/drug effects , Cell Membrane*/metabolism, Humans ; Quaternary Ammonium Compounds/pharmacology ; Candidiasis/drug therapy ; Microbial Sensitivity Tests ; Animals

المؤلفون: Navarro-Mendoza MI; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Pérez-Arques C; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Parker J; Molecular Biosciences Division, School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom., Xu Z; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Kelly S; Institute of Life Science, Swansea University Medical School, Swansea, Wales, United Kingdom., Heitman J; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.

المصدر: MBio [mBio] 2024 Aug 14; Vol. 15 (8), pp. e0166124. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: Ergosterol*/biosynthesis , Ergosterol*/metabolism , Antifungal Agents*/pharmacology , Drug Resistance, Fungal*/genetics , Biosynthetic Pathways*/genetics , Mucor*/genetics , Mucor*/drug effects , Mucor*/metabolism, Humans ; Mucormycosis/microbiology ; Mucormycosis/drug therapy ; Microbial Sensitivity Tests ; Triazoles/pharmacology ; Fungal Proteins/genetics ; Fungal Proteins/metabolism ; Gene Deletion ; Nitriles/pharmacology ; Pyridines/pharmacology ; Oxidoreductases

SCR Organism: Mucor circinelloides

المؤلفون: Bu M; Postdoctoral Research Station, Qiqihar Institute of Medical and Pharmaceutical Sciences Qiqihar 161006, China Postdoctoral Research Station, Heilongjiang University of Chinese Medicine Harbin 150040, China School of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Ren WK; School of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Wang L; School of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Sun CX; School of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Luo R; School of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Guo XS; School of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Lin Y; School of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Ge PL; Postdoctoral Research Station, Heilongjiang University of Chinese Medicine Harbin 150040, China., Liu JC; Postdoctoral Research Station, Qiqihar Institute of Medical and Pharmaceutical Sciences Qiqihar 161006, China.

المصدر: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2024 Aug; Vol. 49 (15), pp. 4139-4147.

نوع المنشور: English Abstract; Journal Article

بيانات الدورية: Publisher: Zhongguo yao xue hui : Zhongguo Zhong yi yan jiu yuan Zhong yao yan jiu suo Country of Publication: China NLM ID: 8913656 Publication Model: Print Cited Medium: Print ISSN: 1001-5302 (Print) Linking ISSN: 10015302 NLM ISO Abbreviation: Zhongguo Zhong Yao Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/drug therapy , Breast Neoplasms*/metabolism , Mitochondria*/drug effects , Mitochondria*/metabolism , Apoptosis*/drug effects , Reactive Oxygen Species*/metabolism , Ergosterol*/analogs & derivatives , Ergosterol*/pharmacology, Humans ; Female ; Animals ; Mice ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Membrane Potential, Mitochondrial/drug effects ; Mice, Inbred BALB C ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Mice, Nude ; Cell Cycle/drug effects

المؤلفون: Sathiyamoorthy J; Actinomycetes Bioprospecting Lab, Centre for Research in Infectious Diseases (CRID), School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, Tamil Nadu, India., Rathore SS; CSIR - Central Institute of Mining and Fuel Research, Dhanbad, Jharkhand, India., Mohan S; Computational Biology Lab, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, Tamil Nadu, India., Uma Maheshwari C; Organic Synthesis Lab, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, Tamil Nadu, India., Ramakrishnan J; Actinomycetes Bioprospecting Lab, Centre for Research in Infectious Diseases (CRID), School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, Tamil Nadu, India.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Aug; Vol. 42 (12), pp. 6013-6026. Date of Electronic Publication: 2023 Jul 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Cryptococcus neoformans*/drug effects , Cryptococcus neoformans*/metabolism , Ergosterol*/biosynthesis , Ergosterol*/metabolism , Ergosterol*/chemistry , Molecular Docking Simulation* , Antifungal Agents*/pharmacology , Antifungal Agents*/chemistry , Molecular Dynamics Simulation*, Furans/pharmacology ; Furans/chemistry ; Ligands ; Protein Binding ; Biosynthetic Pathways/drug effects ; Structure-Activity Relationship ; Humans

المؤلفون: Luo R; College of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Deng SQ; College of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Zhao YX; College of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Wang L; College of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Ren WK; College of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Zou Y; College of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Lin Y; College of Pharmacy, Qiqihar Medical University Qiqihar 161006, China., Bu M; College of Pharmacy, Qiqihar Medical University Qiqihar 161006, China.

المصدر: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2024 Jul; Vol. 49 (13), pp. 3627-3635.

نوع المنشور: English Abstract; Journal Article

بيانات الدورية: Publisher: Zhongguo yao xue hui : Zhongguo Zhong yi yan jiu yuan Zhong yao yan jiu suo Country of Publication: China NLM ID: 8913656 Publication Model: Print Cited Medium: Print ISSN: 1001-5302 (Print) Linking ISSN: 10015302 NLM ISO Abbreviation: Zhongguo Zhong Yao Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/drug therapy , Breast Neoplasms*/genetics , Breast Neoplasms*/metabolism , Apoptosis*/drug effects , Cell Proliferation*/drug effects , Ergosterol*/analogs & derivatives , Ergosterol*/pharmacology , Network Pharmacology*, Humans ; MCF-7 Cells ; Female ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Membrane Potential, Mitochondrial/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Cytochromes c/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics

المؤلفون: Guo H; Liaoning Key Laboratory of Development and Utilization for Natural Products Active Molecules, School of Chemistry and Life Science, Anshan Normal University, Anshan 114005, China. Electronic address: guohua19731210@163.com., Diao QP; Liaoning Key Laboratory of Development and Utilization for Natural Products Active Molecules, School of Chemistry and Life Science, Anshan Normal University, Anshan 114005, China., Han Q; Liaoning Key Laboratory of Development and Utilization for Natural Products Active Molecules, School of Chemistry and Life Science, Anshan Normal University, Anshan 114005, China., He J; Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China., Pan ZH; Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China. Electronic address: pan7260@126.com., Feng T; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China. Electronic address: tfeng@mail.scuec.edu.cn.

المصدر: Fitoterapia [Fitoterapia] 2024 Sep; Vol. 177, pp. 106084. Date of Electronic Publication: 2024 Jun 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

مواضيع طبية MeSH: Ergosterol*/isolation & purification , Ergosterol*/pharmacology , Ergosterol*/analogs & derivatives , Ergosterol*/chemistry , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/isolation & purification , Anti-Inflammatory Agents*/chemistry , Immunosuppressive Agents*/pharmacology , Immunosuppressive Agents*/chemistry , Immunosuppressive Agents*/isolation & purification, Molecular Structure ; Mice ; Animals ; RAW 264.7 Cells ; Nitric Oxide ; B-Lymphocytes/drug effects ; China ; Cell Proliferation/drug effects

المؤلفون: Fattouh N; Department of Natural Sciences, Lebanese American University, Byblos, Lebanon; Department of Biology, Saint George University of Beirut, Beirut, Lebanon., Hdayed D; Department of Natural Sciences, Lebanese American University, Byblos, Lebanon., Hijazi A; Department of Natural Sciences, Lebanese American University, Byblos, Lebanon., Tokajian S; Department of Natural Sciences, Lebanese American University, Byblos, Lebanon., Khalaf RA; Department of Natural Sciences, Lebanese American University, Byblos, Lebanon. Electronic address: roy.khalaf@lau.edu.lb.

المصدر: Journal of global antimicrobial resistance [J Glob Antimicrob Resist] 2024 Sep; Vol. 38, pp. 341-348. Date of Electronic Publication: 2024 Jul 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published by Elsevier Ltd. on behalf of International Society of Chemotherapy for Infection and Cancer Country of Publication: Netherlands NLM ID: 101622459 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-7173 (Electronic) Linking ISSN: 22137165 NLM ISO Abbreviation: J Glob Antimicrob Resist Subsets: MEDLINE

مواضيع طبية MeSH: Candida albicans*/genetics , Candida albicans*/drug effects , Candida albicans*/isolation & purification , Candida albicans*/pathogenicity , Azoles*/pharmacology , Drug Resistance, Fungal* , Antifungal Agents*/pharmacology , Fungal Proteins*/genetics , Fungal Proteins*/metabolism , Ergosterol* , Candidiasis*/microbiology , Mutation* , Microbial Sensitivity Tests*, Lebanon ; Humans ; Animals ; Virulence ; Mice ; Amino Acid Substitution ; Chitin/metabolism ; Female ; Cell Wall ; Disease Models, Animal

المؤلفون: Ghanegolmohammadi F; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwa-no-ha, Kashiwa City, Chiba, 277-8561, Japan., Liu W; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwa-no-ha, Kashiwa City, Chiba, 277-8561, Japan., Xu T; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwa-no-ha, Kashiwa City, Chiba, 277-8561, Japan., Li Y; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwa-no-ha, Kashiwa City, Chiba, 277-8561, Japan., Ohnuki S; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwa-no-ha, Kashiwa City, Chiba, 277-8561, Japan., Kojima T; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwa-no-ha, Kashiwa City, Chiba, 277-8561, Japan., Itto-Nakama K; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwa-no-ha, Kashiwa City, Chiba, 277-8561, Japan., Ohya Y; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwa-no-ha, Kashiwa City, Chiba, 277-8561, Japan. ohya@edu.k.u-tokyo.ac.jp.; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan. ohya@edu.k.u-tokyo.ac.jp.

المصدر: Scientific reports [Sci Rep] 2024 Aug 06; Vol. 14 (1), pp. 17093. Date of Electronic Publication: 2024 Aug 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Ergosterol*/metabolism , Ergosterol*/biosynthesis , Antifungal Agents*/pharmacology , Phenotype*, Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae/drug effects ; Saccharomyces cerevisiae/genetics ; Fluconazole/pharmacology ; Biosynthetic Pathways/drug effects ; Terbinafine/pharmacology

المؤلفون: Kaur B; Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India., Chaudhary GR; Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India., Kaur G; Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India.

المصدر: Molecular pharmaceutics [Mol Pharm] 2024 Jul 01; Vol. 21 (7), pp. 3643-3660. Date of Electronic Publication: 2024 Jun 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Ergosterol*/chemistry , Cobalt*/chemistry , Liposomes*/chemistry , Cholesterol*/chemistry , Lipid Bilayers*/chemistry, Microscopy, Atomic Force

المؤلفون: Milovanovic I; Innovation Center of the Faculty of Technology and Metallurgy, Belgrade, Serbia., Zengin G; Faculty of Science, Department of Biology, University of Selcuk, Konya, Turkey., Maksimovic S; Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia., Tadic V; Institute for Medicinal Plant research 'Dr Josif Pančić', Belgrade, Serbia.

المصدر: Natural product research [Nat Prod Res] 2024 Jul; Vol. 38 (14), pp. 2522-2528. Date of Electronic Publication: 2023 Feb 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE

مواضيع طبية MeSH: Antioxidants*/pharmacology , Antioxidants*/chemistry , Triterpenes*/chemistry , Triterpenes*/analysis , Triterpenes*/pharmacology , Ergosterol* , Reishi*/chemistry , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry, Lipase/metabolism ; Phenols/analysis ; Phenols/chemistry ; Phenols/pharmacology