المؤلفون: Dor Russ, Fabian Glaser, Einat Shaer Tamar, Idan Yelin, Michael Baym, Eric D. Kelsic, Claudia Zampaloni, Andreas Haldimann, Roy Kishony

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/e3d8b35e0db44a9784cca19e12812b34

المؤلفون: Anna Z. Wec, Kathy S. Lin, Jamie C. Kwasnieski, Sam Sinai, Jeff Gerold, Eric D. Kelsic

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: gene therapy, protein engineering, immune evasion, machine learning, AAV capsid design, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.674021/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/9aefd269bf8349888a2ba68db80d1c41

المؤلفون: Eyal Bairey, Eric D. Kelsic, Roy Kishony

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/cea643fe8b934b33891f1d8621ff3dae

المؤلفون: Drew Bryant, Patrick Riley, Ali Bashir, Nina Jain, Sam Sinai, Eric D. Kelsic, George M. Church, Pierce Ogden, Lucy J. Colwell

المصدر: Nature Biotechnology. 39:691-696

مصطلحات موضوعية: Protein family, Computer science, viruses, Biomedical Engineering, Bioengineering, Machine learning, computer.software_genre, Applied Microbiology and Biotechnology, Viral vector, 03 medical and health sciences, 0302 clinical medicine, 030304 developmental biology, 0303 health sciences, Sequence, Protein therapeutics, Artificial neural network, business.industry, Deep learning, Capsid, Molecular Medicine, Sequence space (evolution), Artificial intelligence, business, computer, 030217 neurology & neurosurgery, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::250cd359ae2546fb02bd002a8c101b11
https://doi.org/10.1038/s41587-020-00793-4

المؤلفون: Michael H. Baym, Claudia Zampaloni, Roy Kishony, Andreas Haldimann, Fabian Glaser, Idan Yelin, Dor Russ, Eric D. Kelsic, Einat Shaer Tamar

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Avibactam, Science, 030106 microbiology, Mutant, General Physics and Astronomy, Drug resistance, Microbial Sensitivity Tests, medicine.disease_cause, beta-Lactams, Antimicrobial resistance, General Biochemistry, Genetics and Molecular Biology, beta-Lactamases, Article, Bacterial genetics, Evolution, Molecular, Bacterial evolution, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, Antibiotic resistance, Bacterial Proteins, Drug Resistance, Multiple, Bacterial, medicine, Escherichia coli, lcsh:Science, Genetics, Mutation, Multidisciplinary, Binding Sites, biology, Wild type, General Chemistry, Anti-Bacterial Agents, Molecular Docking Simulation, 030104 developmental biology, chemistry, Amino Acid Substitution, Experimental evolution, Enzyme inhibitor, biology.protein, lcsh:Q, Evolvability, beta-Lactamase Inhibitors, Azabicyclo Compounds

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0d9aff47b7d0289c60b3d57610c7c3
https://doaj.org/article/e3d8b35e0db44a9784cca19e12812b34

المؤلفون: George M. Church, Sam Sinai, Eric D. Kelsic, Nina Jain

مصطلحات موضوعية: High prevalence, Capsid, viruses, Sequence space (evolution), Computational biology, Gene delivery, Biology, Genome, Virus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cdcf0958a04de7c8abec5a7f1c39ae35
https://doi.org/10.1101/2021.04.16.440236

المؤلفون: George M. Church, Eric D. Kelsic

المصدر: Cell and Gene Therapy Insights. 5:523-536

مصطلحات موضوعية: Capsid, Genetic enhancement, Computational biology, Biology, General Economics, Econometrics and Finance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e483464e52a5341116c75a1069813655
https://doi.org/10.18609/cgti.2019.058

المؤلفون: Drew H, Bryant, Ali, Bashir, Sam, Sinai, Nina K, Jain, Pierce J, Ogden, Patrick F, Riley, George M, Church, Lucy J, Colwell, Eric D, Kelsic

المصدر: Nature biotechnology. 39(6)

مصطلحات موضوعية: Machine Learning, Genetic Vectors, Humans, Capsid Proteins, Dependovirus, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::90a5ca7068d4366f7c5c461c737f4f69
https://pubmed.ncbi.nlm.nih.gov/33574611

المؤلفون: Eric D. Kelsic, Pierce Ogden, George M. Church, Sam Sinai

المصدر: Science

مصطلحات موضوعية: Multidisciplinary, Genes, Viral, Fitness landscape, viruses, Mutant, HEK 293 cells, Mutagenesis (molecular biology technique), Computational biology, Protein engineering, Genetic Therapy, Biology, Dependovirus, Protein Engineering, Transfection, Genome, Article, Mutagenesis, Insertional, Capsid, HEK293 Cells, Humans, Capsid Proteins, Gene, Sequence Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b541b24fddf7411950fd9ad1de5f7da1
https://europepmc.org/articles/PMC7197022/

المؤلفون: Michael H. Baym, Eric D. Kelsic, Rotem Gross, Remy Chait, Idan Yelin, Tami D. Lieberman, Roy Kishony

المصدر: Science. 353:1147-1151

مصطلحات موضوعية: 0301 basic medicine, Genotype, 030106 microbiology, Mutant, Microbial Sensitivity Tests, Biology, Mega, Trimethoprim, Bacterial genetics, Evolution, Molecular, 03 medical and health sciences, Ciprofloxacin, Drug Resistance, Bacterial, Selection, Genetic, Evolutionary dynamics, Microbial Viability, Multidisciplinary, Bacteria, Ecology, Adaptation, Physiological, Anti-Bacterial Agents, Phenotype, 030104 developmental biology, Mutation, Mutation (genetic algorithm), Resistant mutants, Visual observation, Adaptation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1aad5e874bfcc12b6633702f68fcd2
https://doi.org/10.1126/science.aag0822