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المؤلفون: Ravindra Kumar, Asya Grinberg, R. Scott Pearsall, Kathryn W. Underwood, Robert G. Matthews, Nicolas Solban, Eric D. Werner, Aaron W. Mulivor, Roselyne Castonguay, Sako Dianne S, Jasbir Seehra, Eleonora Presman
المصدر: Journal of Biological Chemistry. 286:30034-30046
مصطلحات موضوعية: Angiogenesis, GDF2, Angiogenesis Inhibitors, Receptors, Cell Surface, Plasma protein binding, Biology, Bone Morphogenetic Protein Receptors, Type II, Bone morphogenetic protein, Biochemistry, Cell Line, Mice, Antigens, CD, Neoplasms, hemic and lymphatic diseases, Growth Differentiation Factor 2, otorhinolaryngologic diseases, Animals, Humans, Bone morphogenetic protein receptor, Molecular Biology, Binding Sites, Neovascularization, Pathologic, Endoglin, Intracellular Signaling Peptides and Proteins, Growth differentiation factor, Cell Biology, Molecular biology, Transmembrane protein, Protein Structure, Tertiary, Growth Differentiation Factors, Protein Structure and Folding, Bone Morphogenetic Proteins, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d9a63d859a831ed8d8663b1a9eb20b
https://doi.org/10.1074/jbc.m111.260133 -
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المؤلفون: Steven E. Shoelson, Byung-Chul Oh, J. Daniel Frantz, Sirano Dhe-Paganon, Masahiro Nishi, Jongsoon Lee, Lone Hansen, Eric D. Werner
المصدر: Molecular and Cellular Biology. 25:2607-2621
مصطلحات موضوعية: Models, Molecular, animal structures, Molecular Sequence Data, Plasma protein binding, SH2 domain, DNA-binding protein, Cell Line, Mice, Transactivation, Enzyme activator, Growth factor receptor, hemic and lymphatic diseases, Proto-Oncogene Proteins, Two-Hybrid System Techniques, STAT5 Transcription Factor, Animals, Humans, Protein Isoforms, Amino Acid Sequence, Cloning, Molecular, Phosphorylation, Phosphotyrosine, Protein Structure, Quaternary, Molecular Biology, Adaptor Proteins, Signal Transducing, Janus kinase 2, biology, Kinase, Cell Biology, Janus Kinase 2, Protein-Tyrosine Kinases, Milk Proteins, Cell biology, DNA-Binding Proteins, Enzyme Activation, Phosphotransferases (Alcohol Group Acceptor), Trans-Activators, biology.protein, Carrier Proteins, Dimerization, Protein Kinases, Protein Binding, Signal Transduction
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المؤلفون: Eric D. Werner, Lone Hansen, Jongsoon Lee, Minsheng Yuan, Steven E. Shoelson
المصدر: Journal of Biological Chemistry. 279:35298-35305
مصطلحات موضوعية: Insulin Receptor Substrate Proteins, Proto-Oncogene Proteins c-jun, medicine.medical_treatment, Mice, Obese, Saccharomyces cerevisiae, Biology, environment and public health, Biochemistry, Mice, Hyperinsulinism, Two-Hybrid System Techniques, Insulin receptor substrate, Serine, medicine, Animals, Obesity, Phosphorylation, Molecular Biology, Kinase, Insulin, Cell Biology, Phosphoproteins, Molecular biology, Receptor, Insulin, IRS2, IRS1, enzymes and coenzymes (carbohydrates), Insulin receptor, biology.protein, Insulin Resistance
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c1b9a30d810c2d7a66d292ccd71a05
https://doi.org/10.1074/jbc.m405203200 -
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المؤلفون: Morris F. White, Vincent Aguirre, Yong Hee Lee, Steve E. Shoelson, Jodel Giraud, Eric D. Werner
المصدر: Journal of Biological Chemistry. 277:1531-1537
مصطلحات موضوعية: Insulin Receptor Substrate Proteins, Recombinant Fusion Proteins, macromolecular substances, environment and public health, Biochemistry, Cell Line, Phosphatidylinositol 3-Kinases, Two-Hybrid System Techniques, Insulin receptor substrate, Animals, Humans, Insulin, Mitogen-Activated Protein Kinase 8, Phosphorylation, Molecular Biology, biology, Tumor Necrosis Factor-alpha, GRB10, Cell Biology, Phosphoproteins, Receptor, Insulin, IRS2, Anti-Bacterial Agents, Rats, Cell biology, IRS1, enzymes and coenzymes (carbohydrates), Insulin receptor, biology.protein, Mitogen-Activated Protein Kinases, Phosphotyrosine-binding domain, Anisomycin, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88cef8b450d9aaf2b775cf24ed900a09
https://doi.org/10.1074/jbc.m101521200 -
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المؤلفون: Eric D. Werner, Marguerite J. Powell, Ardythe A. McCracken, Kristina B. Kruse, Jeffrey L. Brodsky
المصدر: Yeast. 16:49-55
مصطلحات موضوعية: Protease, Endoplasmic reticulum, medicine.medical_treatment, Mutant, Bioengineering, STIM1, macromolecular substances, Endoplasmic-reticulum-associated protein degradation, Biology, Protein degradation, Applied Microbiology and Biotechnology, Biochemistry, Yeast, Invertase, Genetics, medicine, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::59a18114bb2b9d69fab0c177f6d4a5a3
https://doi.org/10.1002/(sici)1097-0061(20000115)16:1<49::aid-yea506>3.0.co;2-i -
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المؤلفون: William E. Courchesne, Ardythe A. McCracken, Eric D. Werner, Igor V. Karpichev, Andrew Dillin, James E. Ernaga
المصدر: Genetics. 144:1355-1362
مصطلحات موضوعية: Genetics, Mutation, Saccharomyces cerevisiae Proteins, biology, Saccharomyces cerevisiae, Mutant, Fungal genetics, RNA, Fungal, Investigations, Protein degradation, Endoplasmic-reticulum-associated protein degradation, biology.organism_classification, medicine.disease_cause, Molecular biology, Yeast, Complementation, Biochemistry, alpha 1-Antitrypsin, alpha 1-Antitrypsin Deficiency, medicine, RNA, Messenger
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4735eb9d8dcb40f88fc5b631c8a5794d
https://doi.org/10.1093/genetics/144.4.1355 -
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المؤلفون: Ardythe A. McCracken, Eric D. Werner, Jeffrey L. Brodsky
المصدر: Proceedings of the National Academy of Sciences. 93:13797-13801
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Genes, Fungal, Lactacystin, Saccharomyces cerevisiae, macromolecular substances, Cysteine Proteinase Inhibitors, Endoplasmic-reticulum-associated protein degradation, Biology, Endoplasmic Reticulum, Substrate Specificity, Fungal Proteins, chemistry.chemical_compound, Adenosine Triphosphate, Cytosol, Coumarins, Multienzyme Complexes, Microsomes, Multidisciplinary, Endoplasmic reticulum, Proteasome complex, Biological Sciences, Acetylcysteine, Cell biology, Cysteine Endopeptidases, Kinetics, Isocoumarins, Proteasome, Biochemistry, chemistry, Cytoplasm, Microsome
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b6b676d56fab678e99e898ad1fe44e
https://doi.org/10.1073/pnas.93.24.13797 -
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المؤلفون: Karin Vanderkerken, Timothy R. Arnett, Debby Heath, Peter I. Croucher, Mary L. Bouxsein, Michelle L. Key, Les Coulton, Eric D. Werner, Scott Pearsall, Andrew D Chantry, Nicole Abdul, Aaron W. Mulivor, Holly Evans, Jasbir Seehra, Marc Baud’huin
المصدر: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 25(12)
مصطلحات موضوعية: medicine.medical_specialty, Osteolysis, Endocrinology, Diabetes and Metabolism, Recombinant Fusion Proteins, Bone Neoplasms, Bone resorption, Bone remodeling, Metastasis, Mice, Calcification, Physiologic, Osteogenesis, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Orthopedics and Sports Medicine, Bone Resorption, Multiple myeloma, Osteoblasts, business.industry, Bone metastasis, Cancer, Organ Size, medicine.disease, Survival Analysis, Resorption, Activins, Tumor Burden, Endocrinology, HEK293 Cells, business, Multiple Myeloma, Neoplasm Transplantation, Paraproteins, Signal Transduction
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المؤلفون: Ravindra Kumar, Brendan Haigis, Jasbir Seehra, Deanna Smith, Kathryn W. Underwood, Eric D. Werner, Eileen Pobre, R. Scott Pearsall, Lisa Stadmeyer, Jeffrey A. Ucran, Mary L. Bouxsein, Milton Cornwall-Brady, Ernesto Canalis, Vaida Glatt, Asya Grinberg
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 105(19)
مصطلحات موضوعية: medicine.medical_specialty, Activin Receptors, Type II, Ovariectomy, Recombinant Fusion Proteins, Osteoporosis, Bone resorption, Bone and Bones, Bone remodeling, Cell Line, Mice, Osteogenesis, Internal medicine, TGF beta signaling pathway, medicine, Animals, Humans, Bone Resorption, Receptor, Activin type 2 receptors, Multidisciplinary, Lumbar Vertebrae, Chemistry, Activin receptor, Organ Size, Biological Sciences, medicine.disease, Biomechanical Phenomena, Endocrinology, Solubility, Immunoglobulin G, Ovariectomized rat, Female
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4867ccbc6585bed916d270d96fda78d
https://pubmed.ncbi.nlm.nih.gov/18460605 -
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المؤلفون: Steven E. Shoelson, Young In Chi, Eric D. Werner, Sirano Dhe-Paganon, Masahiro Nishi, Lone Hansen
المصدر: Nature structuralmolecular biology. 11(10)
مصطلحات موضوعية: biology, Zipper, Kinase, Chemistry, Protein Conformation, Phenylalanine, Receptor tyrosine kinase, Insulin receptor, Adaptor Proteins, Vesicular Transport, Biochemistry, Structural Biology, biology.protein, Biophysics, Extracellular, Humans, Receptor, Molecular Biology, Tyrosine kinase, Dimerization, Adaptor Proteins, Signal Transducing