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1دورية أكاديمية
المؤلفون: Yuanyuan Qiao, Jesse W Wotring, Charles J Zhang, Xia Jiang, Lanbo Xiao, Andy Watt, Danielle Gattis, Eli Scandalis, Susan Freier, Yang Zheng, Carla D Pretto, Stephanie J Ellison, Eric E Swayze, Shuling Guo, Jonathan Z Sexton, Arul M Chinnaiyan
المصدر: PLoS ONE, Vol 18, Iss 2, p e0281281 (2023)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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2دورية أكاديمية
المؤلفون: Rosie Z Yu, Mark J Graham, Noah Post, Stan Riney, Thomas Zanardi, Shannon Hall, Jennifer Burkey, Colby S Shemesh, Thazha P Prakash, Punit P Seth, Eric E Swayze, Richard S Geary, Yanfeng Wang, Scott Henry
المصدر: Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
مصطلحات موضوعية: antisense oligonucleotide, disposition, mice, pharmacokinetics, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Colby S Shemesh, Rosie Z Yu, Hans J Gaus, Sarah Greenlee, Noah Post, Karsten Schmidt, Michael T Migawa, Punit P Seth, Thomas A Zanardi, Thazha P Prakash, Eric E Swayze, Scott P Henry, Yanfeng Wang
المصدر: Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
مصطلحات موضوعية: antisense oligonucleotide, biotransformation, metabolism, N-acetyl galactosamine, targeted drug delivery, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Niels H Skotte, Amber L Southwell, Michael E Østergaard, Jeffrey B Carroll, Simon C Warby, Crystal N Doty, Eugenia Petoukhov, Kuljeet Vaid, Holly Kordasiewicz, Andrew T Watt, Susan M Freier, Gene Hung, Punit P Seth, C Frank Bennett, Eric E Swayze, Michael R Hayden
المصدر: PLoS ONE, Vol 9, Iss 9, p e107434 (2014)
وصف الملف: electronic resource
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5دورية أكاديمية
المؤلفون: Punit P Seth, Ali Jazayeri, Jeff Yu, Charles R Allerson, Balkrishen Bhat, Eric E Swayze
المصدر: Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
مصطلحات موضوعية: gapmer, hepatotoxicity, immune stimulation, oligonucleotides, α-L-LNA, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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6
المؤلفون: Catherine J. Mummery, Anne Börjesson-Hanson, Daniel J. Blackburn, Everard G. B. Vijverberg, Peter Paul De Deyn, Simon Ducharme, Michael Jonsson, Anja Schneider, Juha O. Rinne, Albert C. Ludolph, Ralf Bodenschatz, Holly Kordasiewicz, Eric E. Swayze, Bethany Fitzsimmons, Laurence Mignon, Katrina M. Moore, Chris Yun, Tiffany Baumann, Dan Li, Daniel A. Norris, Rebecca Crean, Danielle L. Graham, Ellen Huang, Elena Ratti, C. Frank Bennett, Candice Junge, Roger M. Lane
المساهمون: Neurology, Amsterdam Neuroscience - Neurodegeneration, Molecular Neuroscience and Ageing Research (MOLAR)
المصدر: Nature medicine 29(6), 1437-1447 (2023). doi:10.1038/s41591-023-02326-3
Mummery, C J, Börjesson-Hanson, A, Blackburn, D J, Vijverberg, E G B, de Deyn, P P, Ducharme, S, Jonsson, M, Schneider, A, Rinne, J O, Ludolph, A C, Bodenschatz, R, Kordasiewicz, H, Swayze, E E, Fitzsimmons, B, Mignon, L, Moore, K M, Yun, C, Baumann, T, Li, D, Norris, D A, Crean, R, Graham, D L, Huang, E, Ratti, E, Bennett, C F, Junge, C & Lane, R M 2023, ' Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease : a phase 1b, randomized, placebo-controlled trial ', Nature Medicine, vol. 29, no. 6, pp. 1437-1447 . https://doi.org/10.1038/s41591-023-02326-3
Nature Medicine. Nature Publishing Group
Nature Medicine, 29, 1437-1447. Nature Publishing Groupمصطلحات موضوعية: General Medicine, ddc:610, General Biochemistry, Genetics and Molecular Biology
وصف الملف: application/pdf
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7
المؤلفون: Tamilselvan Rajasekaran, Graeme C. Freestone, Rodrigo Galindo-Murillo, Barbara Lugato, Hans Gaus, Michael T. Migawa, Eric. E. Swayze, Thomas E. Cheatham, Punit P. Seth, Stephen Hanessian
المصدر: The Journal of Organic Chemistry. 88:3599-3614
مصطلحات موضوعية: Organic Chemistry
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8
المؤلفون: W. Brad Wan, Audrey Low, Eric E. Swayze, Michael T. Migawa, Guillermo Vasquez, Michael Tanowitz, Punit P. Seth
المصدر: Nucleic Acid Therapeutics. 32:40-50
مصطلحات موضوعية: Stereochemistry, Phosphorothioate Oligonucleotides, Endosomes, Biochemistry, Mice, chemistry.chemical_compound, Therapeutic index, Drug Discovery, Genetics, Animals, Nucleotide, Molecular Biology, chemistry.chemical_classification, Nuclease, biology, Oligonucleotide, Phosphorus, Oligonucleotides, Antisense, Phosphonate, Therapeutic Index, chemistry, biology.protein, Molecular Medicine, Chemical stability, Isopropyl, DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a3100ea938ad4987b8358f461c08ec
https://doi.org/10.1089/nat.2021.0064 -
9
المؤلفون: Tamilselvan Rajasekaran, Graeme C. Freestone, Rodrigo Galindo-Murillo, Barbara Lugato, Lorena Rico, Juan C. Salinas, Hans Gaus, Michael T. Migawa, Eric E. Swayze, Thomas E. Cheatham, Stephen Hanessian, Punit P. Seth
المصدر: J Am Chem Soc
Journal of the American Chemical Society, vol 144, iss 4مصطلحات موضوعية: Oligonucleotides, Organophosphonates, Nucleic Acid Hybridization, General Chemistry, Molecular Dynamics Simulation, Biochemistry, Article, Hydrocarbons, Catalysis, Kinetics, Colloid and Surface Chemistry, Chemical Sciences, Nucleic Acid Conformation, RNA
وصف الملف: application/pdf
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10
المؤلفون: Xue-hai Liang, Cheryl L De Hoyos, Punit P. Seth, Stanley T. Crooke, Graeme C Freestone, Michael E Ǿstergaard, Audrey Low, Guillermo Vasquez, Jinghua Yu, Eric E. Swayze, Michael T. Migawa, W. Brad Wan, Thazha P. Prakash
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Male, AcademicSubjects/SCI00010, Ribonuclease H, Biology, 010402 general chemistry, 01 natural sciences, Mice, 03 medical and health sciences, chemistry.chemical_compound, Organophosphorus Compounds, Therapeutic index, Chemical Biology and Nucleic Acid Chemistry, Genetics, Animals, Humans, 030304 developmental biology, Mice, Inbred BALB C, 0303 health sciences, Nuclease, DNA, Oligonucleotides, Antisense, 0104 chemical sciences, Glucose, Liver, chemistry, NIH 3T3 Cells, Biophysics, biology.protein, Nucleic acid, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4975e50676c63a8c248fb49e9635c5
https://doi.org/10.1093/nar/gkab047