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1دورية أكاديمية
المؤلفون: Abdulkarim Najjar, Jochen Kühnl, Daniela Lange, Camille Géniès, Carine Jacques, Eric Fabian, Anne Zifle, Nicola J. Hewitt, Andreas Schepky
المصدر: Frontiers in Pharmacology, Vol 15 (2024)
مصطلحات موضوعية: daidzein, genistein, PBPK, safety assessment, read-across, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المصدر: Biochemical and Biophysical Research Communications. 651:114-120
مصطلحات موضوعية: Biophysics, Cell Biology, Molecular Biology, Biochemistry
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المؤلفون: Ans Punt, Jochem Louisse, Nicole Pinckaers, Eric Fabian, Bennard van Ravenzwaay
المصدر: Toxicological sciences : an official journal of the Society of Toxicology, 186(1), 18-28
Toxicological sciences : an official journal of the Society of Toxicology 186 (2022) 1مصطلحات موضوعية: PBPK, Team Toxicology, Toxicology, Models, Biological, Rats, C max, Kinetics, Plasma, Liver, PBK, Animals, rat, Toxicologie, VLAG, QIVIVE
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe56a13ffa9a2b9c8bc79caf0c0ef1c6
https://doi.org/10.1093/toxsci/kfab150 -
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المصدر: Chemical research in toxicology. 35(11)
مصطلحات موضوعية: Mice, Cell Culture Techniques, Animals, Hydrophobic and Hydrophilic Interactions, Acetaminophen, Protein Binding
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المصدر: Archives of Toxicology 95 (2021)
Archives of Toxicology, 95, 91-102
Archives of Toxicologyمصطلحات موضوعية: 0301 basic medicine, Primary rat hepatocytes, Health, Toxicology and Mutagenesis, Pharmacology toxicology, Pharmacology, Toxicology, Models, Biological, Proof of Concept Study, 030226 pharmacology & pharmacy, Physiologically based kinetic modelling, Rats, Sprague-Dawley, Excretion, Biliary excretion, 03 medical and health sciences, 0302 clinical medicine, In vivo, Animals, Bile, Estradiol 17β, Scaling factor, Toxicologie, VLAG, Estradiol, Chemistry, General Medicine, In vitro, Hepatobiliary Elimination, 030104 developmental biology, Hepatocytes, Administration, Intravenous, Glucuronide, Toxicokinetics and Metabolism
وصف الملف: application/pdf
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المؤلفون: Peifeng Ren, Felix F. Schmidt, Annika Heckmanns, Mao Wang, Franz Oesch, Anita Samuga, Brandy Riffle, Eric Fabian, Helen Hammer, Robert Landsiedel, Bennard van Ravenzwaay, Oliver Pötz
المصدر: Archives of Toxicology. 94:2663-2682
مصطلحات موضوعية: Male, 0301 basic medicine, Health, Toxicology and Mutagenesis, Quantitative proteomics, 010501 environmental sciences, Toxicology, Proof of Concept Study, 01 natural sciences, Substrate Specificity, Workflow, Xenobiotics, 03 medical and health sciences, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Gene expression, Animals, Humans, Nanotechnology, Inducer, Rats, Wistar, Enzyme inducer, Biotransformation, 0105 earth and related environmental sciences, Cytochrome P-450 Enzyme Inducers, Immunoassay, chemistry.chemical_classification, Pregnane X receptor, biology, Chemistry, Gene Expression Profiling, High-Throughput Nucleotide Sequencing, Reproducibility of Results, General Medicine, Enzyme assay, Toxicokinetics, 030104 developmental biology, Enzyme, Liver, Biochemistry, Enzyme Induction, biology.protein, Female, Transcriptome, Xenobiotic
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المؤلفون: Franz Oesch, Eric Fabian, Daniela Fruth, Jan G. Hengstler, Franz Ingo Berger, Robert Landsiedel
المصدر: Archives of toxicology, 95(12):3717–3744
Archives of Toxicologyمصطلحات موضوعية: Male, Carcinogenicity Tests, Health, Toxicology and Mutagenesis, 610 Medizin, Pharmacology, Toxicology, medicine.disease_cause, Molecular Toxicology, immune system diseases, 610 Medical sciences, Non-genotoxic carcinogen, medicine, Bioassay, Animals, Rats, Wistar, Carcinogen, Carcinogenicity, Micronucleus Tests, Dose-Response Relationship, Drug, Chemistry, Mutagenicity Tests, Liver Neoplasms, virus diseases, General Medicine, genotoxicity, N-vinylpyrrolidone, Comet assay, non-genotoxic carcinogen, carcinogenicity, micronucleus, Pyrrolidinones, Rats, Oxidative Stress, Micronucleus, Micronucleus test, Carcinogens, Female, Comet Assay, Genotoxicity, Ex vivo, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dba1ca17777a99a3a16d07bef8fea76
https://repository.publisso.de/resource/frl:6432213 -
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المصدر: Toxicology letters. 330
مصطلحات موضوعية: 0301 basic medicine, Chromatography, integumentary system, Chemistry, Oecd guideline, Low dose, Human skin, General Medicine, Absorption (skin), Penetration (firestop), Toxicology, In vitro, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Dermal penetration, Dose group, 030217 neurology & neurosurgery
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المؤلفون: Eric Fabian, Markus Frericks, Ivana Fegert, Brandy Riffle, Anne E. Loccisano, James S. Bus, B. Bhaskar Gollapudi
المصدر: Regulatory toxicology and pharmacology : RTP. 113
مصطلحات موضوعية: Biological Stress, Cmax, Developmental toxicity, Molecular Conformation, Administration, Oral, 010501 environmental sciences, Pharmacology, Toxicology, 030226 pharmacology & pharmacy, 01 natural sciences, Heterocyclic Compounds, 4 or More Rings, Risk Assessment, 03 medical and health sciences, Lactones, 0302 clinical medicine, Pharmacokinetics, Pregnancy, Toxicity Tests, Medicine, Toxicokinetics, Animals, 0105 earth and related environmental sciences, Fetus, Dose-Response Relationship, Drug, business.industry, General Medicine, Maximum dose, Toxicity, Female, Rabbits, business
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المؤلفون: Eric Fabian, M. Aggarwal, Richard C. Peffer, Kristie Sullivan, Jon R. Heylings, C. Wiemann, Prakashchandra P V Shah, Jonathan M Akins, Hans Raabe
المصدر: Regulatory Toxicology and Pharmacology. 90:197-205
مصطلحات موضوعية: 0301 basic medicine, Skin Absorption, Best practice, Harmonization, In Vitro Techniques, 010501 environmental sciences, Administration, Cutaneous, Toxicology, Risk Assessment, 01 natural sciences, 03 medical and health sciences, Government Agencies, Environmental health, Toxicity Tests, Animals, Humans, Medicine, Pesticides, Data reporting, Skin, 0105 earth and related environmental sciences, Health risk assessment, business.industry, Reproducibility of Results, Environmental Exposure, General Medicine, Guideline, Pesticide risk assessment, Rats, 030104 developmental biology, Research Design, Models, Animal, North America, Practice Guidelines as Topic, business
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