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1CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation
المؤلفون: Andrew S. Lyon, Michael J. MacCoss, Eric G D Muller, Alex Zelter, Shruthi Viswanath, Axel F. Brilot, Trisha N. Davis, David A. Agard, Andrej Sali, Alison M Maxwell
المصدر: eLife, Vol 10 (2021)
eLifeمصطلحات موضوعية: Saccharomyces cerevisiae Proteins, QH301-705.5, Structural Biology and Molecular Biophysics, microtubule nucleation, Science, Saccharomyces cerevisiae, S. cerevisiae, Crystallography, X-Ray, Microtubules, General Biochemistry, Genetics and Molecular Biology, Mass Spectrometry, 03 medical and health sciences, 0302 clinical medicine, Microtubule, Tubulin, Humans, Binding site, Biology (General), Cytoskeleton, 030304 developmental biology, Microtubule nucleation, 0303 health sciences, Binding Sites, General Immunology and Microbiology, biology, electron microscopy, Chemistry, General Neuroscience, Cryoelectron Microscopy, Antigens, Nuclear, cytoskeleton, General Medicine, Cell Biology, biology.organism_classification, Cytoskeletal Proteins, Structural biology, Helix, Biophysics, biology.protein, Medicine, Calmodulin-Binding Proteins, 030217 neurology & neurosurgery, Microtubule-Organizing Center, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bdb76111604271b162ae2cec9ef0f6d
https://elifesciences.org/articles/65168 -
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المؤلفون: Axel F. Brilot, Michael J. MacCoss, David A. Agard, Andrej Sali, Andrew S. Lyon, Trisha N. Davis, Shruthi Viswanath, Alex Zelter, Eric G D Muller, Alison M Maxwell
مصطلحات موضوعية: Tubulin, biology, Chemistry, Biophysics, biology.protein, Yeast, Microtubule nucleation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eaa3efd620e3497d9fd2618a633ee619
https://doi.org/10.7554/elife.65168.sa2 -
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المؤلفون: Trisha N. Davis, Mark Winey, Tamira Vojnar, Brianna R King, Janet B. Meehl, Eric G D Muller
المساهمون: Lacefield, S
المصدر: Genetics
Genetics, vol 218, iss 2مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Microtubule-associated protein, microtubule nucleation, 1.1 Normal biological development and functioning, Protein subunit, Saccharomyces cerevisiae, Nucleation, Mitosis, Spindle Apparatus, macromolecular substances, motors, Microtubules, 03 medical and health sciences, 0302 clinical medicine, Underpinning research, Microtubule, Genetics, 030304 developmental biology, Microtubule nucleation, Cell Nucleus, Investigation, 0303 health sciences, microtubule associated, biology, microtubule organization, Molecular Motor Proteins, biology.organism_classification, proteins, Cell biology, Spindle apparatus, Microtubule minus-end, Mutation, Microtubule-Associated Proteins, 030217 neurology & neurosurgery, Developmental Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef18de6f7a3fb3531a808784a745d44b
https://doi.org/10.1093/genetics/iyab050 -
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المؤلفون: Amy S. Fabritius, Eileen T. O'Toole, Eric G D Muller, Sue L. Jaspersen, Michele H. Jones, Janet B. Meehl, Mark Winey
المساهمون: Bloom, Kerry S
المصدر: Molecular biology of the cell, vol 29, iss 19
Molecular Biology of the Cellمصطلحات موضوعية: 0301 basic medicine, Saccharomyces cerevisiae Proteins, 1.1 Normal biological development and functioning, Saccharomyces cerevisiae, macromolecular substances, Biology, Models, Biological, Medical and Health Sciences, Spindle elongation, Spindle pole body, 03 medical and health sciences, Models, Underpinning research, Genetics, Centrosome duplication, Phosphorylation, Molecular Biology, Mitosis, Alleles, Anaphase, Centrosome, Cyclin-dependent kinase 1, Cell Cycle, Articles, Cell Biology, Biological Sciences, Phosphoproteins, Biological, Cell biology, Cytoskeletal Proteins, 030104 developmental biology, Spindle Pole Bodies, Mutation, Generic health relevance, Microtubule-Associated Proteins, Developmental Biology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7395b7e2be86c3988142b7a5ce40bfbd
https://doi.org/10.1091/mbc.e18-05-0296 -
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المؤلفون: Trisha N. Davis, Tamira Vojnar, Janet B. Meehl, Eric G D Muller, Mark Winey, Brianna R King
مصطلحات موضوعية: Microtubule minus-end, biology, Microtubule, Chemistry, Microtubule-associated protein, Protein subunit, Saccharomyces cerevisiae, Nucleation, biology.organism_classification, Spindle apparatus, Cell biology, Microtubule nucleation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e0a80e943c79a42165cfcfee9f52092d
https://doi.org/10.1101/2021.01.12.426450 -
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المؤلفون: Shruthi Viswanath, Ivan Rayment, Keenan C. Taylor, Mark Winey, King C. Yabut, Daniel Russel, Neil T. Umbreit, Seung Joong Kim, Eric G D Muller, Trisha N. Davis, Heather A. Van Epps, Massimiliano Bonomi, Javier Velázquez-Muriel, Vadim A. Klenchin, Janet B. Meehl, Michele H. Jones, Andrej Sali
المساهمون: University of California [San Francisco] (UCSF), University of California, University of Washington [Seattle]
المصدر: Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (23), pp.3298-3314. ⟨10.1091/mbc.E17-06-0397⟩مصطلحات موضوعية: 0301 basic medicine, fluorescence resonance energy transfer, PT, Crystallography, X-Ray, Microtubules, Spindle pole body, V.A.K, S.J.K, X-Ray Diffraction, J.M, MC, Monte Carlo, Cytoskeleton, Cell Cycle, IMP, Nuclear Proteins, Articles, SAXS, Cell biology, and E.G.M. analyzed the data. S.V, M.H.J, MTOC, CP, PCM, CBD, well-tempered ensemble, spindle pole body, Saccharomyces cerevisiae Proteins, M.B, fluorescent proteins, Mitosis, cryo-electron microscopy, macromolecular substances, Saccharomyces cerevisiae, Spindle Apparatus, K.C.T, Biology, and E.G.M. wrote the paper γ-TuSC, and E.G.M. designed the research. S.V. and M.B. performed the modeling. S.J.K, Structure-Activity Relationship, 03 medical and health sciences, small-angle x-ray scattering, J.AV-M, Computer Simulation, I.R, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, N.T.U, Molecular Biology, Microtubule nucleation, Centrosome, A.S, H.A.V.E, S.V, FPs, and E.G.M. designed the experiments. S.V, pericentriolar material, Bayes Theorem, Microtubule organizing center, Cell Biology, γ-tubulin small complex, metallothionein, parallel tempering, Spindle apparatus, microtubule-organizing center, 030104 developmental biology, Förster resonance energy transfer, Spindle Pole Bodies, M.W, Gamma-tubulin complex, and E.G.M. conducted the experiments. . V.A.K, central plaque, K.C.Y, T.N.D, FRET, cryo-EM, Integrative Modeling Platform, SPB, WTE, MTH, calmodulin-binding domain, D.R
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d80d8100f9d6de48e5db97b9e82a40
https://doi.org/10.1091/mbc.e17-06-0397 -
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المؤلفون: Daniel Jaschob, Riccardo Pellarin, Andrej Sali, Eric G D Muller, Bryan A. Sundin, Massimiliano Bonomi, Seung Joong Kim, Daniel Russel, Trisha N. Davis, Michael Riffle, Richard Ramsden
المصدر: Molecular & Cellular Proteomics. 13:2812-2823
مصطلحات موضوعية: Special Issue Articles, Saccharomyces cerevisiae Proteins, Bayesian probability, Posterior probability, Monte Carlo method, Analytical chemistry, Saccharomyces cerevisiae, Bayesian inference, Biochemistry, Analytical Chemistry, Quantitative Biology::Subcellular Processes, Bayes' theorem, Bacterial Proteins, Protein Interaction Mapping, Fluorescence Resonance Energy Transfer, Computer Simulation, Protein Structure, Quaternary, Molecular Biology, Quantitative Biology::Biomolecules, Molecular Structure, Chemistry, Bayes Theorem, Photobleaching, Luminescent Proteins, Förster resonance energy transfer, Metric (mathematics), Biological system, Monte Carlo Method, Algorithms
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a52657aae706364cb71992b20bb0d2a
https://doi.org/10.1074/mcp.m114.040824 -
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المصدر: Cell Cycle. 9:3619-3628
مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Cell cycle checkpoint, Biorientation, BUB1, Kinesins, Mitosis, Antineoplastic Agents, Cell Cycle Proteins, Saccharomyces cerevisiae, Protein Serine-Threonine Kinases, Biology, Microtubules, chemistry.chemical_compound, Aurora Kinases, Report, Kinetochores, Molecular Biology, Metaphase, Cohesin, Kinetochore, Nocodazole, Intracellular Signaling Peptides and Proteins, Mitotic spindle organization, Cell Biology, Cell biology, Spindle checkpoint, Microscopy, Fluorescence, chemistry, Mutation, Microtubule-Associated Proteins, Developmental Biology
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المؤلفون: Frank Uhlmann, Brian E. Snydsman, John Mc Intyre, Trisha N. Davis, Stefan Weitzer, Eric G D Muller
المصدر: The EMBO Journal
مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Cohesin complex, Chromosomal Proteins, Non-Histone, Recombinant Fusion Proteins, Saccharomyces cerevisiae, chromosome segregation, cohesin, S. cerevisiae, Cell Cycle Proteins, Article, General Biochemistry, Genetics and Molecular Biology, Chromosome segregation, 03 medical and health sciences, 0302 clinical medicine, Fluorescence Resonance Energy Transfer, Sister chromatids, Molecular Biology, 030304 developmental biology, Genetics, 0303 health sciences, General Immunology and Microbiology, biology, Cohesin, Kinetochore, General Neuroscience, SMC protein, Nuclear Proteins, biology.organism_classification, Protein Structure, Tertiary, Protein Subunits, Förster resonance energy transfer, Smc proteins, FRET, Biophysics, biological phenomena, cell phenomena, and immunity, 030217 neurology & neurosurgery
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المؤلفون: John R. Yates, Brian E. Snydsman, Joshua A. Rosenberg, Gregory C. Tomlin, Eric G D Muller, W. Hayes McDonald, Kathleen L. Gould
المصدر: Molecular Biology of the Cell. 17:3793-3805
مصطلحات موضوعية: Fission, Gene Expression, Nuclear Proteins, Articles, Spindle Apparatus, macromolecular substances, Cell Biology, Biology, Septation initiation network, Spindle pole body, Yeast, Cell biology, Protein Transport, Microtubule, Centrosome, Schizosaccharomyces, Fluorescence Resonance Energy Transfer, Schizosaccharomyces pombe Proteins, Central function, Microtubule-Associated Proteins, Molecular Biology, Gene Deletion, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cd2525e78b803a52ad1694189b0489
https://doi.org/10.1091/mbc.e06-01-0039