المؤلفون: Amber L. Southwell, Sonia Franciosi, Erika B. Villanueva, Yuanyun Xie, Laurie A. Winter, Janaki Veeraraghavan, Alan Jonason, Boguslaw Felczak, Weining Zhang, Vlad Kovalik, Sabine Waltl, George Hall, Mahmoud A. Pouladi, Ernest S. Smith, William J. Bowers, Maurice Zauderer, Michael R. Hayden

المصدر: Neurobiology of Disease, Vol 76, Iss , Pp 46-56 (2015)

مصطلحات موضوعية: Semaphorin, Immunotherapy, Passive immunization, Huntington disease, Preclinical, Transgenic mice, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996115000145; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/99a93dc1282c4cf6b5dc56f2438c4a79

المؤلفون: Emilie Tresse, Joao N. Duarte, Gisela Jimenez-Duran, Shohreh Issazadeh-Navikas, Oliver Kretz, Desiree Loreth, Tobias Goldmann, Yawei Liu, Erika B Villanueva, Marco Prinz, Patrick Ejlerskov

المصدر: Villanueva, E B, Tresse, E, Liu, Y, Duarte, J N, Jimenez-Duran, G, Ejlerskov, P, Kretz, O, Loreth, D, Goldmann, T, Prinz, M & Issazadeh-Navikas, S 2021, ' Neuronal TNFα, not α-syn, underlies PDD-like disease progression in IFNβ-KO mice ', Annals of Neurology, vol. 90, no. 5, pp. 789-807 . https://doi.org/10.1002/ana.26209

مصطلحات موضوعية: Faculty of Health and Medical Sciences, Lewy Body Disease, Amyloid beta, alpha-synuclein, Plaque, Amyloid, Neuropathology, phosphorylated tau, Parkinson's disease dementia, Inclusion bodies, neuroinflammation, Pathogenesis, chemistry.chemical_compound, Medicine, Animals, interferon-beta, Neuroinflammation, Alpha-synuclein, Mice, Knockout, Neurons, tumor necrosis factor alpha, Lewy body, biology, business.industry, Tumor Necrosis Factor-alpha, Neurodegeneration, Parkinson Disease, medicine.disease, amyloid-beta, nervous system diseases, nervous system, Neurology, chemistry, Neuroinflammatory Diseases, Cancer research, biology.protein, Disease Progression, Lewy Bodies, Neurology (clinical), business, Neuroglia

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b55ccc20235ff8195895b406f982c2
https://pubmed.ncbi.nlm.nih.gov/34476836

المؤلفون: Sabine Waltl, Dagmar E. Ehrnhoefer, Boguslaw Felczak, Lorenzo Casal, Amber L. Southwell, Meenalochani Sivasubramanian, Lisa M. Anderson, Anita Fazeli, Xiaofan Qiu, Erika B. Villanueva, Yuanyun Xie, Michelle Tsang, Michael R. Hayden

المصدر: Human Molecular Genetics. 27:239-253

مصطلحات موضوعية: 0301 basic medicine, HECT domain, Huntingtin, NF-E2-Related Factor 2, Ubiquitin-Protein Ligases, Nerve Tissue Proteins, Context (language use), Biology, Mitochondrion, medicine.disease_cause, Mice, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, Animals, Molecular Biology, Genetics (clinical), Tumor Suppressor Proteins, Articles, General Medicine, medicine.disease, Corpus Striatum, Mitochondria, 3. Good health, Astrogliosis, Ubiquitin ligase, Cell biology, Neostriatum, Disease Models, Animal, Oxidative Stress, Huntington Disease, 030104 developmental biology, medicine.anatomical_structure, Astrocytes, biology.protein, 030217 neurology & neurosurgery, Oxidative stress, Astrocyte

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8162b1e4d2606c1c8c03bb5479382b0d
https://doi.org/10.1093/hmg/ddx394

المؤلفون: Amber L. Southwell, Hailey Findlay-Black, Yuanyun Xie, Bethany Fitsimmons, Michael E. Østergaard, C. Frank Bennett, Niels H. Skotte, Louisa Dal Cengio, Punit P. Seth, Crystal N. Doty, Michael R. Hayden, Erika B. Villanueva, Douglas R. Langbehn, Lynn A. Raymond, Lisa M. Anderson, Holly B. Kordasiewicz, Eric E. Swayze, Matthew P. Parsons, Nicholas S. Caron

المصدر: Science Translational Medicine. 10

مصطلحات موضوعية: Male, Primates, 0301 basic medicine, Dopamine and cAMP-Regulated Phosphoprotein 32, congenital, hereditary, and neonatal diseases and abnormalities, Huntingtin, Mutant, Single-nucleotide polymorphism, Disease, Anxiety, Biology, medicine.disease_cause, 03 medical and health sciences, Cognition, 0302 clinical medicine, Limbic system, Huntington's disease, mental disorders, Limbic System, medicine, Animals, Humans, Huntingtin Protein, Mutation, Behavior, Animal, Brain, General Medicine, Oligonucleotides, Antisense, medicine.disease, nervous system diseases, 3. Good health, Cortex (botany), Disease Models, Animal, Huntington Disease, 030104 developmental biology, medicine.anatomical_structure, nervous system, Female, Mutant Proteins, Atrophy, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7234a2400b48305341d35ff493f065e4
https://doi.org/10.1126/scitranslmed.aar3959

المؤلفون: Alberto Siddu, Abid Oueslati, Halyna Pankevych, Yuanyun Xie, Oskar W. Smrzka, Francesca Cicchetti, Amber L. Southwell, Louisa Dal Cengio, Michael R. Hayden, Michela Parth, Markus Burkert, Seungyun Ko, Nina Salhat, Linda Suzanne David, Erika B. Villanueva, Stefan Bartl

المصدر: Experimental therapeutics – preclinical.

مصطلحات موضوعية: medicine.anatomical_structure, biology, Mutant protein, Mutant, Cell, biology.protein, medicine, Huntingtin Protein, Extracellular, Antibody, Mode of action, Intracellular, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4e6c6a6144745fc65591b4cce441736e
https://doi.org/10.1136/jnnp-2018-ehdn.245

المؤلفون: Boguslaw Felczak, Sabine Waltl, George Hall, Erika B. Villanueva, Yuanyun Xie, Michael R. Hayden, Weining Zhang, Ernest S. Smith, Amber L. Southwell, Maurice Zauderer, Vlad Kovalik, Laurie A. Winter, Alan S. Jonason, Sonia Franciosi, William J. Bowers, Mahmoud A. Pouladi, Janaki Veeraraghavan

المصدر: Neurobiology of Disease, Vol 76, Iss, Pp 46-56 (2015)

مصطلحات موضوعية: SEMA4D, Mice, Transgenic, Semaphorins, Neuropathology, Motor Activity, Mouse behavior, lcsh:RC321-571, Mice, Atrophy, Semaphorin, Antigens, CD, medicine, Animals, Transgenic mice, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Neuroinflammation, Passive immunization, Neurodegeneration, Antibodies, Monoclonal, Brain, Huntington disease, medicine.disease, Preclinical, Oligodendrocyte, Disease Models, Animal, medicine.anatomical_structure, Neurology, Immunotherapy, Cognition Disorders, Psychology, Cell activation, Neuroscience, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4695d8f490b8ca0232dade08a084827b
https://doi.org/10.1016/j.nbd.2015.01.002

المؤلفون: Holly Kordasiewicz, Michael R. Hayden, Clarence Frank Bennett, Crystal N. Doty, Erika B. Villanueva, Punit P. Seth, Kuljeet Vaid, Susan M. Freier, Niels H. Skotte, Eugenia Petoukhov, Amber L. Southwell, Jeffrey B. Carroll, Michael E. Østergaard, Eric E. Swayze, Andrew T. Watt, Yuanyun Xie

المصدر: Molecular Therapy. 22:2093-2106

مصطلحات موضوعية: Huntingtin, Mutant, Nerve Tissue Proteins, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Injections, Rats, Sprague-Dawley, Mice, Drug Discovery, Genetics, Huntingtin Protein, Animals, Humans, Gene silencing, Gene Silencing, Molecular Targeted Therapy, Cognitive decline, Molecular Biology, Pharmacology, Oligonucleotide, Brain, Oligonucleotides, Antisense, Thionucleotides, Molecular biology, Rats, 3. Good health, Mice, Inbred C57BL, Disease Models, Animal, Huntington Disease, Humanized mouse, Cancer research, Molecular Medicine, Mutant Proteins, Original Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c5894b01f5d4fee6755f2bee232356
https://doi.org/10.1038/mt.2014.153

المؤلفون: Svetlana Simtchouk, Nichole E. Gill, Kirsten R. Wolthers, Erika B. Villanueva, Jonathan P. Little, Andis Klegeris, Douglas G. Walker, Stephanie M. Schindler

المصدر: Molecular and Cellular Neuroscience. 60:88-96

مصطلحات موضوعية: Cell signaling, MAP Kinase Signaling System, Biology, Monocytes, Mitochondrial Proteins, Interferon-gamma, Cellular and Molecular Neuroscience, Interferon, Cell Line, Tumor, medicine, Humans, Cytotoxic T cell, Molecular Biology, Cells, Cultured, Neuroinflammation, Inflammation, Microglia, Interleukins, Brain, Interleukin, Cell Biology, TFAM, Molecular biology, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, Tumor necrosis factor alpha, Extracellular Space, Transcription Factors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93d9451160733734c3e0b8227292b72
https://doi.org/10.1016/j.mcn.2014.04.003

المؤلفون: Michael R. Hayden, X. William Yang, Erika B. Villanueva, Niels H. Skotte, Crystal N. Doty, Amber L. Southwell, Jeffrey B. Carroll, Vlad Kovalik, Sonia Franciosi, Weining Zhang, Mahmoud A. Pouladi, Jennifer A. Collins, Simon C. Warby, Yuanyun Xie

المصدر: Human Molecular Genetics. 22:18-34

مصطلحات موضوعية: Genetically modified mouse, congenital, hereditary, and neonatal diseases and abnormalities, Transgene, Mice, Transgenic, Biology, medicine.disease_cause, Polymorphism, Single Nucleotide, Loss of heterozygosity, Mice, Huntington's disease, mental disorders, Genetics, medicine, Animals, Humans, Gene silencing, Gene Silencing, Allele, Promoter Regions, Genetic, Molecular Biology, Genetics (clinical), Mutation, Articles, General Medicine, medicine.disease, nervous system diseases, Disease Models, Animal, Huntington Disease, Rotarod Performance Test, Humanized mouse

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1b299ddb98f5fe7f29092cae6621d9
https://doi.org/10.1093/hmg/dds397

المؤلفون: Erika B. Villanueva, Jonathan P. Little, Andis Klegeris

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::389051abbfc2e2d675d0c4de8f4c6d08
https://doi.org/10.2174/9781681081717115020005