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1دورية أكاديمية
المؤلفون: Alan C. Cheng, Elizabeth M. Doherty, Sheree Johnstone, Erin F. DiMauro, Jennifer Dao, Abhinav Luthra, Jay Ye, Jie Tang, Thomas Nixey, Xiaoshan Min, Philip Tagari, Les P. Miranda, Zhulun Wang
المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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المؤلفون: Jane Aldrich, Shelley Allen, Erika Araujo, Joanne Bronson, Amanda Bryant-Friedrich, Shana K. Cyr, Erin F. DiMauro, Carolyn Dzierba, Amanda L. Garner, Gunda I. Georg, Nicole C. Goodwin, Krupanandan Haranahalli, Rong Huang, Katerina Leftheris, Tricia L. May-Dracka, Margaret E. Olson, Maria-Jesus Blanco
المصدر: Journal of Medicinal Chemistry. 66:3651-3655
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Molecular Medicine, Biochemistry
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المؤلفون: David A. Candito, Vladimir Simov, Anmol Gulati, Solomon Kattar, Ryan W. Chau, Blair T. Lapointe, Joey L. Methot, Duane E. DeMong, Thomas H. Graham, Ravi Kurukulasuriya, Mitchell H. Keylor, Ling Tong, Gregori J. Morriello, John J. Acton, Barbara Pio, Weiguo Liu, Jack D. Scott, Michael J. Ardolino, Theodore A. Martinot, Matthew L. Maddess, Xin Yan, Hakan Gunaydin, Rachel L. Palte, Spencer E. McMinn, Lisa Nogle, Hongshi Yu, Ellen C. Minnihan, Charles A. Lesburg, Ping Liu, Jing Su, Laxminarayan G. Hegde, Lily Y. Moy, Janice D. Woodhouse, Robert Faltus, Tina Xiong, Paul Ciaccio, Jennifer A. Piesvaux, Karin M. Otte, Matthew E. Kennedy, David Jonathan Bennett, Erin F. DiMauro, Matthew J. Fell, Santhosh Neelamkavil, Harold B. Wood, Peter H. Fuller, J. Michael Ellis
المصدر: Journal of Medicinal Chemistry. 65:16801-16817
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Joey L. Methot, David A Candito, Sheila Ranganath, Zangwei Xu, Xavier Fradera, Abdelghani Achab, Erin F. DiMauro, Haiyan Xu, Samuel M. Levi, Brandon A. Vara, Brian M. Lacey, Mark Bittinger, Jennifer Piesvaux, Dustin M Smith, Alexander Pasternak, Jongwon Lim, David Jonathan Bennett, J. Richard Miller, Charles A. Lesburg, Shuhei Kawamura
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: 010405 organic chemistry, Chemistry, medicine.drug_class, Kinase, medicine.medical_treatment, T cell, Organic Chemistry, T-cell receptor, Carboxamide, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Cytokine, medicine.anatomical_structure, Diaminopyrimidine, Drug Discovery, Cancer research, medicine, Kinome, B cell
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المؤلفون: Mitchell H. Keylor, Anmol Gulati, Solomon D. Kattar, Rebecca E. Johnson, Ryan W. Chau, Kaila A. Margrey, Michael J. Ardolino, Cayetana Zarate, Kelsey E. Poremba, Vladimir Simov, Gregori J. Morriello, John J. Acton, Barbara Pio, Xin Yan, Rachel L. Palte, Spencer E. McMinn, Lisa Nogle, Charles A. Lesburg, Donovon Adpressa, Shishi Lin, Santhosh Neelamkavil, Ping Liu, Jing Su, Laxminarayan G. Hegde, Janice D. Woodhouse, Robert Faltus, Tina Xiong, Paul J. Ciaccio, Jennifer Piesvaux, Karin M. Otte, Harold B. Wood, Matthew E. Kennedy, David Jonathan Bennett, Erin F. DiMauro, Matthew J. Fell, Peter H. Fuller
المصدر: Journal of medicinal chemistry. 65(1)
مصطلحات موضوعية: Antiparkinson Agents, Models, Molecular, Structure-Activity Relationship, Drug Design, Drug Discovery, Quinazolines, Molecular Medicine, Biological Availability, Brain, Humans, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Protein Kinase Inhibitors
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6دورية أكاديمية
المؤلفون: David J Matson, Darryl T Hamamoto, Howard Bregman, Melanie Cooke, Erin F DiMauro, Liyue Huang, Danielle Johnson, Xingwen Li, Jeff McDermott, Carrie Morgan, Ben Wilenkin, Annika B Malmberg, Stefan I McDonough, Donald A Simone
المصدر: PLoS ONE, Vol 10, Iss 9, p e0138140 (2015)
وصف الملف: electronic resource
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7Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors
المؤلفون: Blair T. Lapointe, Jack D. Scott, Xin Cindy Yan, Haiqun Tang, Janice D Woodhouse, Kaleen Konrad Childers, Robert Faltus, Erin F. DiMauro, Solomon Kattar, Charles S. Yeung, Ravi Kurukulasuriya, Vladimir Simov, Hakan Gunaydin, Anmol Gulati, Joey L. Methot, Rachel L. Palte, Ellen C. Minnihan, Greg Morriello, J. Michael Ellis, Harold B. Wood, Santhosh Neelamkavil, Karin M. Otte, Michael J. Ardolino, Barbara Pio, Ping Liu, Laxminarayan G Hegde, Matthew J. Fell, Vanessa L. Rada, Peter Fuller, Paul J Ciaccio
المصدر: RSC Med Chem
مصطلحات موضوعية: Pharmacology, 0303 health sciences, Trifluoromethyl, Chemistry, Metabolite, Organic Chemistry, Pharmaceutical Science, Pyrazole, Leucine-rich repeat, Biochemistry, LRRK2, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, 030220 oncology & carcinogenesis, Drug Discovery, Molecular Medicine, Kinome, Penetrant (biochemical), Linker, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8d45ea7dd7adda70471298a4476afa
https://europepmc.org/articles/PMC8292993/ -
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المؤلفون: Abbas Walji, Sonia DelRizzo, Elisabetta Bianchi, Jonathan D. Mortison, Vladimir Simov, Yingzi Yue, Thomas J. Tucker, Peter Goldenblatt, Alexander Stoeck, Raffaele Ingenito, Edward DiNunzio, Christopher Sondey, Hui Wan, Erin F. DiMauro, Venkat Sriraman, Victor Serebrov, My Sam Mansueto, Scott A. Johnson, Todd Mayhood, Guo Feng, Michael D. Altman
المصدر: European journal of medicinal chemistry. 224
مصطلحات موضوعية: MafG Transcription Factor, NF-E2-Related Factor 2, Peptide, Electrophoretic Mobility Shift Assay, Pembrolizumab, chemistry.chemical_compound, Structure-Activity Relationship, Drug Stability, Transcription (biology), Neoplasms, Drug Discovery, medicine, Humans, Homology modeling, Ternary complex, Transcription factor, Pharmacology, chemistry.chemical_classification, Chemistry, Organic Chemistry, Cancer, General Medicine, DNA, respiratory system, medicine.disease, Antioxidant Response Elements, Drug Design, Cancer research, Peptides, Half-Life, HeLa Cells
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المؤلفون: Emily A. Peterson, Stephanie D. Geuns-Meyer, Matthew Weiss, Hongbing Huang, Katrina W. Copeland, Violeta Yu, Erin F. DiMauro, Hua Gao, Alessandro Boezio, Russell Graceffa, Daniel S. La, Hakan Gunaydin, Robert T. Fremeau, Christiane Boezio, Margaret Chu-Moyer, Joseph Ligutti, Bryan D. Moyer, Kristin L. Andrews, Robert S. Foti
المصدر: Bioorganic & Medicinal Chemistry Letters. 28:2103-2108
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Gene isoform, Aryl, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Context (language use), Biochemistry, Combinatorial chemistry, Sulfonamide, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Drug Discovery, NAV1, Molecular Medicine, Bioisostere, Pharmacophore, Selectivity, Molecular Biology
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المؤلفون: Loren Berry, Hakan Gunaydin, Nagasree Chakka, Jeffrey R. Simard, Angel Guzman-Perez, Matthew H. Plant, Erin F. DiMauro, Kristin L. Andrews, Liyue Huang, Jacinthe Gingras, Howard Bregman
المصدر: European Journal of Medicinal Chemistry. 137:63-75
مصطلحات موضوعية: 0301 basic medicine, Azetidine, Drug Evaluation, Preclinical, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Receptors, Glycine, Aminothiazole, Drug Discovery, Humans, Glycine receptor, ADME, Pharmacology, Sulfonamides, Virtual screening, Dose-Response Relationship, Drug, Molecular Structure, Drug discovery, Chemistry, Organic Chemistry, General Medicine, Potentiator, Combinatorial chemistry, Molecular Docking Simulation, 030104 developmental biology, Pharmacophore