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1دورية أكاديمية
المؤلفون: Qiu Ying Lau, Yoke Yan Fion Tan, Vanessa Chai Yin Goh, David Jing Qin Lee, Fui Mee Ng, Esther H. Q. Ong, Jeffrey Hill, Cheng San Brian Chia
المصدر: Antibiotics, Vol 4, Iss 4, Pp 424-434 (2015)
مصطلحات موضوعية: drug library screen, drug repurposing, drug repositioning, MRSA, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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2
المصدر: BMC genomics. 23(Suppl 1)
مصطلحات موضوعية: Binding Sites, Deep Learning, Transforming Growth Factor beta, Smad2 Protein, Smad3 Protein, Cell Line, Signal Transduction
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3Designing an ultra-short antibacterial peptide with potent activity against Mupirocin-resistant MRSA
المؤلفون: Siew Mei Samantha Ng, Jeffrey Hill, Qiu Ying Lau, Esther H. Q. Ong, Chu Yang Fann Ong, Giovinna Arfan, Cheng San Brian Chia, Fui Mee Ng
المصدر: Chemical Biology & Drug Design. 93:4-11
مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, Drug, Cell Survival, media_common.quotation_subject, Antimicrobial peptides, Mupirocin, Microbial Sensitivity Tests, Skin infection, medicine.disease_cause, 01 natural sciences, Biochemistry, Cell Line, Microbiology, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Amino Acid Sequence, Mode of action, Pathogen, media_common, Pharmacology, 010405 organic chemistry, business.industry, Organic Chemistry, medicine.disease, Antibacterial peptide, Anti-Bacterial Agents, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Staphylococcus aureus, Drug Design, Molecular Medicine, Peptides, business
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4
المؤلفون: Qi An Ang, Giovinna Arfan, Cheng San Brian Chia, Esther H. Q. Ong, Fui Mee Ng, Chu Yang Fann Ong
المصدر: Chemical biologydrug designREFERENCES. 97(6)
مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, medicine.drug_class, Cell Survival, Antibiotics, Human skin, Mupirocin, Microbial Sensitivity Tests, Skin infection, medicine.disease_cause, 01 natural sciences, Biochemistry, Microbiology, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, medicine, Structure–activity relationship, Humans, Amino Acid Sequence, Mode of action, Pharmacology, 010405 organic chemistry, business.industry, Organic Chemistry, Fibroblasts, medicine.disease, 0104 chemical sciences, Anti-Bacterial Agents, Nanostructures, 010404 medicinal & biomolecular chemistry, chemistry, Staphylococcus aureus, Drug Design, Molecular Medicine, Leucine, business, Peptides
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5
المؤلفون: Roland Jureen, GuiFang Xu, Esther H. Q. Ong, Hui Si Vivian Ching, Qiu Ying Lau, C. S. Brian Chia, Siew Mei Samantha Ng, Jeffrey Hill, Fui Mee Ng
المصدر: International Journal of Peptide Research and Therapeutics. 23:481-491
مصطلحات موضوعية: 0301 basic medicine, Drug, media_common.quotation_subject, 030106 microbiology, Antimicrobial peptides, Bioengineering, Mupirocin, Peptide, Skin infection, medicine.disease_cause, Biochemistry, Analytical Chemistry, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, medicine, Mode of action, Cytotoxicity, media_common, chemistry.chemical_classification, business.industry, medicine.disease, chemistry, Staphylococcus aureus, Molecular Medicine, lipids (amino acids, peptides, and proteins), business
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6
المؤلفون: Jeffrey Hill, Joma Joy, Grace Lin, Nurul Dinie, Justina Fulwood, Sin Yin Chew, Xiaoying Koh-Stenta, Sugunavathi Sepramaniam, Xin Hui Chew, Rong Li, Melgious Jin Yan Ang, May Ann Lee, Alex Matter, Weixuan Yu, Zhiyuan Ke, Anna Ngo, Hwa Hwa Chung, Susmitha Vuddagiri, Kanda Sangthongpitag, Klement Foo, Vithya Manoharan, C. S. Brian Chia, Sravanthy Manesh, Esther H. Q. Ong, Nithya Baburajendran, Chuhui Huang, Zekui Perlyn Kwek, John Liang Kuan Wee, Yun Shan Chew, Priya Retna, Thomas H. Keller, Anders Poulsen, Si Si Liew, Choon Bing Low, Vishal Pendharkar
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: chemistry.chemical_classification, Methyltransferase, Chemistry, Organic Chemistry, Biochemistry, Cell biology, 3D cell culture, Enzyme, Mechanism of action, Covalent bond, Histone methyltransferase, Drug Discovery, medicine, Epigenetics, medicine.symptom, Transferase inhibitor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a957218bb54c41c184fbdaf7cb115a0
https://europepmc.org/articles/PMC6580565/ -
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المؤلفون: Vithya Manoharan, Yun Xuan Wong, Esther H. Q. Ong, Kassoum Nacro, John Liang Kuan Wee, Zekui Perlyn Kwek, Sharon Xiaodai Lim, Jeffrey Hill, Yun Shan Chew, Zhi Ying Poh, S. Tiong Ong, Thomas H. Keller, Li Jun Ding, Joma Joy, Vishal Pendharkar, Samantha Guo, Kanda Sangthongpitag, Anders Poulsen, Hai Yan Yang, May Ann Lee, Boping Liu, Meng Ling Choong, Duraiswamy Athisayamani Jeyaraj, Joseph Cherian, Melvyn Ho
المصدر: Journal of Medicinal Chemistry. 59:3063-3078
مصطلحات موضوعية: 0301 basic medicine, Myeloid, Fusion Proteins, bcr-abl, Administration, Oral, Biological Availability, Antineoplastic Agents, Chemistry Techniques, Synthetic, Mice, SCID, Protein Serine-Threonine Kinases, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, hemic and lymphatic diseases, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Molecular Targeted Therapy, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, biology, Chemistry, Kinase, EIF4E, Intracellular Signaling Peptides and Proteins, Myeloid leukemia, medicine.disease, Xenograft Model Antitumor Assays, Leukemia, Eukaryotic Initiation Factor-4E, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mitogen-activated protein kinase, Immunology, Cancer research, biology.protein, Molecular Medicine, Female, Stem cell
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المؤلفون: Yoke Yan Fion Tan, Jeffrey Hill, Qiu Ying Lau, Vanessa Chai Yin Goh, Fui Mee Ng, Esther H. Q. Ong, David Jing Qin Lee, Cheng San Brian Chia
المصدر: Antibiotics, Vol 4, Iss 4, Pp 424-434 (2015)
Antibiotics
Volume 4
Issue 4
Pages 424-434مصطلحات موضوعية: Microbiology (medical), Drug, medicine.drug_class, media_common.quotation_subject, Antibiotics, drug repositioning, MRSA, Skin infection, medicine.disease_cause, Biochemistry, Microbiology, Article, medicine, Pharmacology (medical), General Pharmacology, Toxicology and Pharmaceutics, Pathogen, Repurposing, media_common, drug repurposing, Drug discovery, business.industry, lcsh:RM1-950, medicine.disease, Drug repositioning, Infectious Diseases, lcsh:Therapeutics. Pharmacology, Staphylococcus aureus, business, drug library screen
وصف الملف: application/pdf
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9
المؤلفون: Kiat Whye Kong, Qiu Ying Lau, Mohammad Alfatah, Shawn Hoon, Prakash Arumugam, Fui Mee Ng, Timothy Barkham, Siew Mei Samantha Ng, Jeffrey Hill, Jeanette W. P. Teo, Cheng San Brian Chia, Esther H. Q. Ong, Jia Mao Yap
المصدر: European journal of medicinal chemistry. 150
مصطلحات موضوعية: 0301 basic medicine, Drug, Antifungal Agents, Cell Survival, media_common.quotation_subject, 030106 microbiology, Antimicrobial peptides, Antifungal drug, Microbial Sensitivity Tests, Microbiology, 03 medical and health sciences, Structure-Activity Relationship, Drug Resistance, Fungal, Drug Discovery, Candida albicans, medicine, Humans, Peptide library, Fluconazole, media_common, Pharmacology, biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, General Medicine, Fibroblasts, Antimicrobial, biology.organism_classification, Corpus albicans, 030104 developmental biology, Peptides, medicine.drug
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10
المؤلفون: Anders Poulsen, Jayantha Gunaratne, Stephen M. Cohen, Kanda Sangthongpitag, Jeffrey Hill, Vishal Pendharkar, Suat Peng Neo, Liu Boping, Wei Zhang, Esther H. Q. Ong
المصدر: Cellular Signalling. 27:436-442
مصطلحات موضوعية: PTEN, endocrine system, Vaults, Phosphatidylinositol 3-Kinases, eIF-2 Kinase, Cell Line, Tumor, Humans, PERK inhibitors, Protein kinase A, Protein Kinase Inhibitors, Protein kinase B, PI3K/AKT/mTOR pathway, Vault Ribonucleoprotein Particles, biology, Forkhead Box Protein O1, Kinase, Endoplasmic reticulum, PTEN Phosphohydrolase, Nuclear Proteins, Forkhead Transcription Factors, Hep G2 Cells, Cell Biology, Endoplasmic Reticulum Stress, Cell biology, HEK293 Cells, Amino Acid Substitution, Unfolded protein response, biology.protein, MVP, ER stress, Proto-Oncogene Proteins c-akt, HeLa Cells, Signal Transduction