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المؤلفون: Alexandre Wohlkonig, Florence Leroux, Nicolas Willand, Ngoc Chau Tran, Xue Li, Arnaud Machelart, Marion Flipo, Catherine Piveteau, Ruxandra Gref, René Wintjens, Martin Moune, Priscille Brodin, Baptiste Villemagne, Benoit Deprez, Alain R. Baulard
المساهمون: Department of Bio-engineering Sciences, Structural Biology Brussels, Institut des Sciences Moléculaires d'Orsay (ISMO), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)
المصدر: ACS Infectious Diseases
ACS Infectious Diseases, American Chemical Society, 2020, 6 (3), pp.366-378. ⟨10.1021/acsinfecdis.9b00277⟩
ACS infectious diseases, 6 (3مصطلحات موضوعية: 0301 basic medicine, Drug, Ethionamide booster, in vivo POC, Tuberculosis, mice, media_common.quotation_subject, 030106 microbiology, Pharmacology, Biology, Crystallography, X-Ray, Mycobacterium tuberculosis, 03 medical and health sciences, In vivo, Drug Discovery, medicine, [CHIM]Chemical Sciences, Animals, Ethionamide/chemistry, ComputingMilieux_MISCELLANEOUS, media_common, Tuberculosis/drug therapy, Mice, Inbred BALB C, Mycobacterium tuberculosis/drug effects, Oxadiazoles/chemistry, Sciences bio-médicales et agricoles, biology.organism_classification, medicine.disease, Structure-activity relationship, In vitro, 3. Good health, 030104 developmental biology, Infectious Diseases, Repressor Proteins/antagonists & inhibitors, Antitubercular Agents/chemistry, Drug Design, Ethionamide, Female, Fragment-based drug design, Infectious agent, medicine.drug
وصف الملف: 1 full-text file(s): application/pdf
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المؤلفون: Pierre Rousselot-Pailley, Jean-Michel Wieruszeski, Isabelle Landrieu, Xavier Hanoulle, Guy Lippens, Alain R. Baulard, Camille Locht
المساهمون: Synthèse, structure et fonction des biomolécules (SSFB), Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Mécanismes moléculaires de la pathogenèse bactérienne, Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by INSERM, CNRS, Région Nord-Pas de Calais, and Institut Pasteur de Lille (IFR142). X. H. and P. R.-P. were funded by a doctoral fellowship of the Ministry of Research and Technology (MRT, France).
المصدر: Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2006, 58 (4), pp.768. ⟨10.1093/jac/dkl332⟩مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Metabolite, MESH: Ethionamide/metabolism, Antimycobacterial, MESH: Mycobacterium smegmatis/growth & development, chemistry.chemical_compound, Pharmacology (medical), Prodrugs, Ethionamide, Biotransformation, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, Antibacterial agent, 0303 health sciences, Isoniazid, MESH: Prodrugs/chemistry, Prodrug, MESH: Ethionamide/chemistry, 3. Good health, MESH: Oxygenases/metabolism, Infectious Diseases, Biochemistry, tuberculosis, Oxygenases, MESH: Magnetic Resonance Spectroscopy/methods, MESH: Bacterial Proteins/metabolism, medicine.drug, Microbiology (medical), medicine.drug_class, Mycobacterium smegmatis, Context (language use), MESH: Magnetic Resonance Spectroscopy/instrumentation, Biology, Microbiology, 03 medical and health sciences, Bacterial Proteins, medicine, HRMAS-NMR, Humans, 030304 developmental biology, Pharmacology, MESH: Biotransformation, MESH: Humans, 030306 microbiology, MESH: Mycobacterium smegmatis/metabolism, thioamide, biology.organism_classification, Culture Media, chemistry, MESH: Prodrugs/metabolism, MESH: Culture Media, Mycobacterium
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506b4b30b250858c6d5424348ca579c9
https://hal.archives-ouvertes.fr/hal-00103724 -
3مورد إلكتروني
المؤلفون: Flipo, Marion, Frita, Rosangela, Bourotte, Marilyne, Martínez-Martínez, María S, Boesche, Markus, Boyle, Gary W, Derimanov, Geo, Drewes, Gerard, Gamallo, Pablo, Ghidelli-Disse, Sonja, Gresham, Stephanie, Jiménez, Elena, de Mercado, Jaime, Pérez-Herrán, Esther, Porras-De Francisco, Esther, Rullas, Joaquín, Casado, Patricia, Leroux, Florence, Piveteau, Catherine, Kiass, Mehdi, Mathys, Vanessa, Soetaert, Karine, Megalizzi, Véronique, Tanina, ABDALKARIM, Wintjens, René, Antoine, Rudy, Brodin, Priscille, Delorme, Vincent, Moune, Martin, Djaout, Kamel, Slupek, Stéphanie, Kemmer, Christian, Gitzinger, Marc, Ballell, Lluis, Mendoza-Losana, Alfonso, Lociuro, Sergio, Déprez, Benoit, Barros-Aguirre, David, Remuiñán, Modesto MJ, Willand, Nicolas, Baulard, Alain R
المصدر: Science Translational Medicine, 14 (643
مصطلحات الفهرس: Sciences bio-médicales et agricoles, Animals, Antitubercular Agents -- pharmacology -- therapeutic use, Ethionamide -- chemistry -- pharmacology -- therapeutic use, Mice, Mycobacterium tuberculosis, Prodrugs -- pharmacology -- therapeutic use, Tuberculosis -- drug therapy, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article
URL:
https://dipot.ulb.ac.be/dspace/bitstream/2013/349752/3/aaz6280_STM_Main_EditionV7.pdf http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/349752 http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
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