المؤلفون: Jeremy Ortillon, Jean-Christophe Le Bail, Elise Villard, Bertrand Léger, Bruno Poirier, Christine Girardot, Sandra Beeske, Laetitia Ledein, Véronique Blanchard, Patrice Brieu, Souâd Naimi, Philip Janiak, Etienne Guillot, Marco Meloni

المصدر: Frontiers in Physiology, Vol 12 (2021)

مصطلحات موضوعية: YAP/TAZ, diabetes, inflammation, endothelial cells, vascular complications, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.665994/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/3a95d3ec179f4dad879a949878c90db4

المؤلفون: Elise F. Villard, PhD, Aurélie Thedrez, PhD, Jorg Blankenstein, PhD, Mikaël Croyal, BSc, Thi-Thu-Trang Tran, PhD, Bruno Poirier, PhD, Jean-Christophe Le Bail, PhD, Stéphane Illiano, PhD, Estelle Nobécourt, MD, PhD, Michel Krempf, MD, PhD, Dirk J. Blom, MD, PhD, A. David Marais, MD, Philip Janiak, PhD, Anthony J. Muslin, MD, PhD, Etienne Guillot, PhD, Gilles Lambert, PhD

المصدر: JACC: Basic to Translational Science, Vol 1, Iss 6, Pp 419-427 (2016)

مصطلحات موضوعية: familial hypercholesterolemia, LDL receptor, lipoprotein(a), PCSK9, primary human hepatocytes, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452302X16300675; https://doaj.org/toc/2452-302X

URL الوصول: https://doaj.org/article/a2e8609f65714b7b9f3d883bea5a8386

المؤلفون: Christophe Philippo, Jean-Christophe Le Bail, Bruno Cornet, Pascale Briand, Pascal Paul, Philip Janiak, Etienne Guillot, Valerie Fourgous, Michel Partiseti

المصدر: Journal of Pharmacology and Experimental Therapeutics. 374:283-294

مصطلحات موضوعية: 0301 basic medicine, Agonist, Protein Conformation, medicine.drug_class, CHO Cells, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, 0302 clinical medicine, Ethanolamine, Drug Discovery, Lysophosphatidic acid, Adipocytes, medicine, Animals, Humans, Receptors, Lysophosphatidic Acid, Benzofuran, Receptor, Benzofurans, Cell growth, Antagonist, Brain, Cell Differentiation, Muscle, Smooth, beta-Arrestin 2, Rats, Molecular Docking Simulation, 030104 developmental biology, chemistry, Guanosine 5'-O-(3-Thiotriphosphate), Molecular Medicine, Rabbits, medicine.symptom, 030217 neurology & neurosurgery, Muscle Contraction, Muscle contraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8979ed336011fbc08acf3bf4d7ea0d9e
https://doi.org/10.1124/jpet.120.265454

المؤلفون: Bruno Poirier, Christine Girardot, Elise F. Villard, Bertrand Léger, Jeremy Ortillon, Etienne Guillot, Laetitia Ledein, Sandra Beeské, Jean-Christophe Le Bail, Philip Janiak, Véronique Blanchard, Patrice Brieu, Souâd Naimi, Marco Meloni

المصدر: Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)

مصطلحات موضوعية: 0301 basic medicine, vascular complications, Physiology, Regulator, Inflammation, Endothelial activation, 03 medical and health sciences, 0302 clinical medicine, In vivo, Diabetes mellitus, Physiology (medical), medicine, QP1-981, YAP/TAZ, Original Research, diabetes, Vascular inflammation, Chemistry, Monocyte, medicine.disease, In vitro, endothelial cells, Cell biology, 030104 developmental biology, medicine.anatomical_structure, inflammation, 030220 oncology & carcinogenesis, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c2abba4d2779b6434f359577b80960

المؤلفون: Brahim El Mathari, Véronique Briand, Etienne Guillot, Philip Janiak, Alain Corbier, Marie-Pierre Harnist, Pascale Briand, Frédérique Guilbert, Bruno Poirier, Alice Raffenne-Devillers

المصدر: Peptides. 142

مصطلحات موضوعية: Cardiac function curve, Cardiomyopathy, Dilated, medicine.medical_specialty, Cardiac output, Physiology, Cardiomyopathy, 030209 endocrinology & metabolism, Blood Pressure, Mice, Transgenic, Biochemistry, Contractility, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, 0302 clinical medicine, Endocrinology, Heart Rate, Internal medicine, Medicine, Animals, Humans, Peripheral Vascular Diseases, Ejection fraction, business.industry, Stroke Volume, medicine.disease, Apelin, Vasodilation, Disease Models, Animal, medicine.anatomical_structure, Heart failure, Cardiology, Vascular resistance, Vascular Resistance, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f6428487c518a090906e664162d68a
https://pubmed.ncbi.nlm.nih.gov/33965442

المؤلفون: Jean-Christophe Le Bail, BS Valentin Blanchard, Sophie Ho-Van-Guimbal, Sandra Beeské, Gihad Dargazanli, Thi Thu Trang Tran, Marie-Pierre Pruniaux, Mikaël Croyal, Olivier Bergis, Etienne Guillot, Denis Boulay, Gilles Lambert, BS Kévin Chemello, Philip Janiak, Elise F. Villard, Bruno Poirier

المساهمون: Lallemant, Pascal, CHOPIN - - CHOPIN2016 - ANR-16-RHUS-0007 - RHUS - VALID, Diabète athérothrombose et thérapies Réunion Océan Indien (DéTROI), Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Sanofi Aventis R&D [Chilly-Mazarin], ANR-16-RHUS-0007,CHOPIN,CHOPIN(2016), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de La Réunion (UR)

المصدر: JACC : Basic to Translational Science
JACC : Basic to Translational Science, 2020, 5 (6), pp.549-557. ⟨10.1016/j.jacbts.2020.03.008⟩
JACC : Basic to Translational Science, Elsevier on behalf of the American College of Cardiology Foundation, 2020, 5 (6), pp.549-557. ⟨10.1016/j.jacbts.2020.03.008⟩

مصطلحات موضوعية: 0301 basic medicine, biology, Chemistry, PCSK9, liver-humanized mice, [SDV]Life Sciences [q-bio], Endogeny, Lipoprotein(a), 030204 cardiovascular system & hematology, Pharmacology, 3. Good health, [SDV] Life Sciences [q-bio], 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, low-density lipoprotein receptor, proprotein convertase subtilisin/kexin type 9, In vivo, lipoprotein(a), LDL receptor, biology.protein, Cardiology and Cardiovascular Medicine, Ex vivo, Alirocumab, Lipoprotein

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca66067ab1872febfbf590ab39aa80c
http://hdl.handle.net/20.500.12278/36814

المؤلفون: Daniele Catalucci, Marie-Pierre Pruniaux, B Biton, P Cervello, Pascale Briand, J.C. Le Bail, F Guilbert, Philip Janiak, Bruno Poirier, A Corbier, M Barandalla-Sobrados, B El-Mathari, V Letang, Etienne Guillot, S Le-Claire

المصدر: European Heart Journal. 40

مصطلحات موضوعية: Senescence, Contractility, medicine.medical_specialty, business.industry, Internal medicine, Heart failure, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ecef4da85fce1760d7e226a98d9197a3
https://doi.org/10.1093/eurheartj/ehz745.0027

المؤلفون: Ilya Khantalin, Stéphane Ramin-Mangata, Brice Nativel, Stéphanie Billon-Crossouard, Mikaël Croyal, Rose Hélène Blanchard, Etienne Guillot, Kévin Chemello, Michel Krempf, Valentin Blanchard, Gilles Lambert, Audrey Aguesse, Bruno Poirier, Philip Janiak, Elise F. Villard, Christophe Boixel, Jean-Christophe Le Bail, Aurélie Thedrez, Thi-Thu-Trang Tran

المساهمون: Nutrition périnatale [Nantes] (Centres de Recherche en Nutrition Humaine - CRNH), Centre de Recherche en Nutrition Humaine - Ouest, Sanofi-Aventis R&D, SANOFI Recherche, Physiologie des Adaptations Nutritionnelles [UMR_A1280] (PhAN), Institut National de la Recherche Agronomique (INRA)-Université de Nantes (UN), Diabète athérothrombose et thérapies Réunion Océan Indien (DéTROI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de La Réunion (UR), Groupe d'Etude sur l'Inflammation Chronique et l'Obésité (GEICO), Université de La Réunion (UR), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), INRA: UMR1280 Physiologie des adaptations (UMR1280), Institut National de la Recherche Agronomique (INRA), Bureau d'Économie Théorique et Appliquée (BETA), Institut National de la Recherche Agronomique (INRA)-Université de Strasbourg (UNISTRA)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA)

المصدر: Clinical Science
Clinical Science, Portland Press, 2018, 132 (10), pp.1075-1083. ⟨10.1042/CS20180040⟩

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, plasma lipoproteins, Apolipoprotein B, [SDV]Life Sciences [q-bio], receptors, 030204 cardiovascular system & hematology, Antibodies, Monoclonal, Humanized, Apoprotein(a), PCSK9, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, low-density lipoproteins, medicine, Animals, Receptor, ComputingMilieux_MISCELLANEOUS, Alirocumab, Cross-Over Studies, biology, Chemistry, Catabolism, Anticholesteremic Agents, PCSK9 Inhibitors, Antibodies, Monoclonal, General Medicine, Lipoprotein(a), Lipids, Macaca fascicularis, Cholesterol, 030104 developmental biology, Endocrinology, biology.protein, Kexin, Female, lipids (amino acids, peptides, and proteins), Lipoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458694c8ac4928c889b310c06efa5781
https://doi.org/10.1042/cs20180040

المؤلفون: Philippe Péron, Marie-Aude Chabanaud, Gwladys Langot, Etienne Guillot, Florence Goumy, Patrick Mougenot, Cecile Pascal, Olivier Crespin, Fabrice Viviani, Majdi Ben-Hassine, Friedemann Schmidt, Eykmar Fett, Jean-Christophe Le Bail, Jean-Luc Ragot, Bénédicte Onofri, Rommel Dadji-Faïhun, Christophe Philippo, Thao Van-Pham, Catherine Monseau, Olivier Venier, Jerome Menegotto, Florence Chatelain-Egger, Marie-Pierre Pruniaux, François Pacquet, Philippe Chamiot-Clerc, Eric Nicolai, Claudie Namane

المصدر: Bioorganic & Medicinal Chemistry Letters. 26:25-32

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Clinical Biochemistry, Pharmaceutical Science, Oxadiazole, 01 natural sciences, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Diacylglycerol O-Acyltransferase, Thiadiazoles, Drug Discovery, Humans, Molecule, Structure–activity relationship, Enzyme Inhibitors, Solubility, Molecular Biology, Oxadiazoles, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, chemistry, Molecular Medicine, Diacylglycerol Acyltransferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccd83610869fd9f5432e155ed4fbc2f
https://doi.org/10.1016/j.bmcl.2015.11.046

المؤلفون: Elise F, Villard, Aurélie, Thedrez, Jorg, Blankenstein, Mikaël, Croyal, Thi-Thu-Trang, Tran, Bruno, Poirier, Jean-Christophe, Le Bail, Stéphane, Illiano, Estelle, Nobécourt, Michel, Krempf, Dirk J, Blom, A David, Marais, Philip, Janiak, Anthony J, Muslin, Etienne, Guillot, Gilles, Lambert

المصدر: JACC. Basic to translational science

مصطلحات موضوعية: PCSK9, primary human hepatocytes, familial hypercholesterolemia, lipoprotein(a), LDL receptor, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::bbd0e5960fab55c4d9bee120ad07c438
https://pubmed.ncbi.nlm.nih.gov/29308438