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1
المؤلفون: Barun Bhhatarai, Stephan C. Schürer, Hugh Rosen, Edward Roberts, Emanuela Repetto, Euijung Jo, Yasushi Kohno, Sean Riley, Steven J. Brown, Miguel Guerrero
المصدر: ACS Chemical Biology. 7:1975-1983
مصطلحات موضوعية: Models, Molecular, Allosteric regulation, CHO Cells, Ligands, Biochemistry, Article, Radioligand Assay, chemistry.chemical_compound, Cricetulus, Cricetinae, Animals, natural sciences, Phosphorylation, Receptor, biology, Sphingosine, Extramural, Chinese hamster ovary cell, General Medicine, biology.organism_classification, Receptors, Lysosphingolipid, Allosteric enzyme, chemistry, biology.protein, Molecular Medicine, lipids (amino acids, peptides, and proteins), Allosteric Site
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2
المؤلفون: Greg Reinhart, Gye Won Han, Hans Desale, M. Germana Sanna, Mark T. Griffith, Peter Kuhn, Bryan Clemons, Hugh Rosen, Stephan C. Schuerer, Raymond C. Stevens, Fiona Scott, Euijung Jo, Michael A. Hanson, Stuart M. Cahalan, Christopher B. Roth
المصدر: Science. 335:851-855
مصطلحات موضوعية: Models, Molecular, Binding Sites, Multidisciplinary, Sphingosine, Protein Conformation, Recombinant Fusion Proteins, Organophosphonates, Biology, Crystallography, X-Ray, Sphingolipid, Article, Cell biology, Receptors, Lysosphingolipid, chemistry.chemical_compound, Protein structure, Biochemistry, chemistry, Mutagenesis, Extracellular, Anilides, Muramidase, Binding site, Receptor, S1PR1, G protein-coupled receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2b1bc96c574ee723d56f8ca41c0e0a
https://doi.org/10.1126/science.1215904 -
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المؤلفون: Timothy P. Spicer, Peter Hodder, Pedro J. Gonzalez-Cabrera, Steven J. Brown, Peter Chase, Jacqueline Chapman, Hugh Rosen, Marie Therese Schaeffer, Euijung Jo, Stephan C. Schürer
المصدر: ACS Chemical Biology. 3:486-498
مصطلحات موضوعية: Models, Molecular, Agonist, Protein Conformation, medicine.drug_class, Sphingosine-1-phosphate receptor, Biosensing Techniques, CHO Cells, Biology, Ligands, Biochemistry, Article, Structure-Activity Relationship, chemistry.chemical_compound, Cricetulus, Cricetinae, medicine, Animals, Cluster Analysis, Sphingosine-1-phosphate, Phosphorylation, Binding site, Receptor, Oxadiazoles, Binding Sites, General Medicine, Ligand (biochemistry), Receptors, Lysosphingolipid, chemistry, Docking (molecular), Molecular Probes, Biophysics, Molecular Medicine, Calcium, 5-HT1 receptor, Protein Binding
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المؤلفون: Pedro J. Gonzalez-Cabrera, Hugh Rosen, Ian Parker, Michael D. Cahalan, Chi-Huey Wong, M. Germana Sanna, Sindy H. Wei, Euijung Jo, David Marsolais, Sheng-Kai Wang, Wei-Chieh Cheng, Melanie P. Matheu, Anthony S. Don
المصدر: Nature Chemical Biology. 2:434-441
مصطلحات موضوعية: Lymphocyte, Organophosphonates, Pulmonary Edema, CHO Cells, Biology, Models, Biological, Capillary Permeability, Mice, Paracrine signalling, chemistry.chemical_compound, Sphingosine, In vivo, Cricetinae, medicine, Animals, Humans, Anilides, Lymphocytes, Autocrine signalling, Receptor, Molecular Biology, Cells, Cultured, Antagonist, Stereoisomerism, Cell Biology, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, Receptors, Lysosphingolipid, Phenotype, medicine.anatomical_structure, chemistry, Immunology, Lymph Nodes, Lysophospholipids, Signal transduction, Evans Blue
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5
المؤلفون: Hugh Rosen, M. Germana Sanna, Ian Parker, Sheng-Kai Wang, Melanie P. Matheu, Sindy H. Wei, Chi-Huey Wong, Euijung Jo, Michael D. Cahalan
المصدر: Nature Immunology. 6:1228-1235
مصطلحات موضوعية: Agonist, medicine.medical_specialty, medicine.drug_class, Lymphocyte, T cell, Immunology, Thiophenes, Biology, Mice, Cell Movement, Sphingosine, T-Lymphocyte Subsets, Internal medicine, medicine, Lymph node stromal cell, Animals, Immunology and Allergy, Receptor, Cells, Cultured, Lymphatic Vessels, Mice, Inbred BALB C, Oxadiazoles, Cell Migration Inhibition, Cell biology, Endothelial stem cell, Receptors, Lysosphingolipid, Endocrinology, Lymphatic system, medicine.anatomical_structure, lipids (amino acids, peptides, and proteins), Lymph Nodes, Lysophospholipids
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6
المؤلفون: Pedro J. Gonzalez-Cabrera, Shobha Thangada, Daniel A. Osborne, Euijung Jo, Gabor Tigyi, M. Germana Sanna, Hugh Rosen, Abby L. Parrill, Timothy Hla
المصدر: Chemistry & Biology. 12:703-715
مصطلحات موضوعية: Models, Molecular, MAPK/ERK pathway, Clinical Biochemistry, Drug Evaluation, Preclinical, Ligands, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Sphingosine, Cricetinae, Drug Discovery, Phosphorylation, Internalization, Receptor, media_common, Mitogen-Activated Protein Kinase 1, Oxadiazoles, 0303 health sciences, Mitogen-Activated Protein Kinase 3, General Medicine, rac GTP-Binding Proteins, Cell biology, Receptors, Lysosphingolipid, 030220 oncology & carcinogenesis, Molecular Medicine, lipids (amino acids, peptides, and proteins), Signal transduction, Signal Transduction, Receptor recycling, Agonist, medicine.drug_class, media_common.quotation_subject, Thiophenes, Protein Serine-Threonine Kinases, Biology, Cell Line, 03 medical and health sciences, Proto-Oncogene Proteins, medicine, Animals, Humans, Molecular Biology, Protein kinase B, 030304 developmental biology, Pharmacology, Binding Sites, organic chemicals, Cell Membrane, Protein Structure, Tertiary, Enzyme Activation, chemistry, Molecular Probes, Mutation, Lysophospholipids, Proto-Oncogene Proteins c-akt
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المؤلفون: Peter St George-Hyslop, Euijung Jo, Paul E. Fraser, R. Peter Rand, Nola Fuller
المصدر: Journal of Molecular Biology. 315:799-807
مصطلحات موضوعية: Alpha-synuclein, Mutation, Parkinson's disease, Vesicle, Mutant, Plasma protein binding, medicine.disease_cause, medicine.disease, nervous system diseases, chemistry.chemical_compound, Protein structure, chemistry, Biochemistry, Structural Biology, medicine, Molecular Biology, POPC
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8
المصدر: Journal of Biological Chemistry. 275:34328-34334
مصطلحات موضوعية: Male, animal diseases, Membrane lipids, Lipid Bilayers, Mutation, Missense, Synucleins, Phospholipid, Nerve Tissue Proteins, Microscopy, Atomic Force, Biochemistry, Protein Structure, Secondary, chemistry.chemical_compound, Membrane fluidity, Humans, heterocyclic compounds, Amino Acid Sequence, Lipid bilayer, Molecular Biology, Lipid Transport, Aged, Aged, 80 and over, Alpha-synuclein, Phosphatidylethanolamine, Sequence Homology, Amino Acid, Circular Dichroism, Cell Membrane, Brain, Lipid metabolism, Cell Biology, Lipid Metabolism, nervous system diseases, Cell biology, nervous system, chemistry, alpha-Synuclein, Chromatography, Thin Layer
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff2112f73d38de0e03ded42a254a49e
https://doi.org/10.1074/jbc.m004345200 -
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المؤلفون: David Westaway, D. M. Xu, T. Kawakai, Agnes Supala, D. M. Zhang, Christopher Janus, Fusheng Chen, James R. Woodgett, Masaki Nishimura, Lars Lannfelt, Paul Milman, P. St. George-Hyslop, Ekaterina Rogaeva, Howard T.J. Mount, G. Levesque, Gang Yu, Paul E. Fraser, Euijung Jo, Richard Rozmahel, Erin Holmes, L. Ruel, Kari M. Mattila, Q. Bi, Monika Duthie, Lyne Levesque, Yan Liang
المصدر: Nature Medicine. 5:164-169
مصطلحات موضوعية: Beta-catenin, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Presenilin, Cell Line, symbols.namesake, Alzheimer Disease, Presenilin-2, mental disorders, Presenilin-1, medicine, Humans, beta Catenin, Cell Nucleus, Mutation, biology, Endoplasmic reticulum, NF-kappa B, Wnt signaling pathway, Membrane Proteins, Biological Transport, General Medicine, Golgi apparatus, nervous system diseases, Cell biology, Cytoskeletal Proteins, nervous system, Catenin, Trans-Activators, biology.protein, symbols, Signal transduction, Protein Binding, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1933b34c760cdf17006bafe35d485484
https://doi.org/10.1038/5526 -
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المؤلفون: Euijung Jo, Jack Blazyk, Joan M. Boggs
المصدر: Biochemistry. 37:13791-13799
مصطلحات موضوعية: Dose-Response Relationship, Drug, Chemistry, Circular Dichroism, Lipid Bilayers, Antimicrobial peptides, Magainin, Galactosylceramides, Phosphatidylglycerols, Photoaffinity Labels, Biochemistry, Protein Structure, Secondary, Kinetics, chemistry.chemical_compound, Anti-Infective Agents, Amide, Membrane fluidity, Biophysics, Animals, lipids (amino acids, peptides, and proteins), Lipid bilayer phase behavior, Peptides, Lipid bilayer, Antimicrobial Cationic Peptides