المؤلفون: Ewelina Testoni, Natalie L Stephenson, Pedro Torres‐Ayuso, Anna A Marusiak, Eleanor W Trotter, Andrew Hudson, Cassandra L Hodgkinson, Christopher J Morrow, Caroline Dive, John Brognard

المصدر: EMBO Molecular Medicine, Vol 8, Iss 2, Pp 105-116 (2016)

مصطلحات موضوعية: ABL1 mutations, dasatinib, imatinib, non‐small cell lung cancer, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/09b706bec30d4b42952219ab90a03b7c

المؤلفون: John Brognard, Owen J. Sansom, Tony Hunter, Crispin J. Miller, Ewelina Testoni, Matthew Collier, Ross Overman, Isabelle Green, Chris Phillips, Hannah K. Pollard, Claire Brassington, Jon A. Read, Lorena A. Puto, Phil Chapman, Susan Mason, Karen Blyth, Yaoyong Li, Eleanor W. Trotter, Hayeon Baik, Natalie L. Stephenson, Anna A. Marusiak

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0722c76c95b7bbc4901db1e2b3ae68
https://doi.org/10.1158/0008-5472.22409912

المؤلفون: Ewelina Testoni, John Brognard, Cassandra L Hodgkinson, Anna A. Marusiak, Eleanor W. Trotter, Natalie L. Stephenson, Andrew M Hudson, Pedro Torres-Ayuso, Caroline Dive, Christopher J. Morrow

المصدر: Testoni, E, Stephenson, N L, Torres-Ayuso, P, Marusiak, A A, Trotter, E W, Hudson, A, Hodgkinson, C L, Morrow, C J, Dive, C & Brognard, J 2016, ' Somatically mutated ABL1 is an actionable and essential NSCLC survival gene ', EMBO Molecular Medicine, vol. 8, no. 2, pp. 105-16 . https://doi.org/10.15252/emmm.201505456
EMBO Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Respiratory System, ABL1 mutations, Bioinformatics, medicine.disease_cause, Mice, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, hemic and lymphatic diseases, dasatinib, Proto-Oncogene Proteins c-abl, Cancer, Mutation, ABL, Manchester Cancer Research Centre, Kinase, Research Support, Non-U.S. Gov't, Dasatinib, Treatment Outcome, 030220 oncology & carcinogenesis, Imatinib Mesylate, Heterografts, Molecular Medicine, medicine.drug, non‐small cell lung cancer, Cell Survival, Antineoplastic Agents, 03 medical and health sciences, Report, Cell Line, Tumor, Journal Article, medicine, Animals, Humans, Lung cancer, neoplasms, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, Imatinib, medicine.disease, respiratory tract diseases, Disease Models, Animal, 030104 developmental biology, Imatinib mesylate, imatinib, Cancer research, Mutant Proteins, business, Reports

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588373a0dd762246419e79d9a650f3e0
https://doi.org/10.15252/emmm.201505456

المؤلفون: Ewelina Testoni, Matthew Collier, Isabelle Green, Christopher R. Phillips, Claire Brassington, Yaoyong Li, Phil Chapman, Ross Overman, Crispin J. Miller, Hannah Pollard, Karen Blyth, Lorena A. Puto, Eleanor W. Trotter, Susan M. Mason, Anna A. Marusiak, Tony Hunter, Owen J. Sansom, John Brognard, Hayeon Baik, Jon Read, Natalie L. Stephenson

المصدر: Cancer research. 76(3)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Carcinogenesis, MAP Kinase Signaling System, p38 mitogen-activated protein kinases, Mice, Nude, Biology, medicine.disease_cause, Article, MAP2K7, 03 medical and health sciences, Mice, CDKN2B, medicine, Animals, Humans, Mutation, Mice, Inbred BALB C, MAP kinase kinase kinase, Kinase, MAP Kinase Kinase Kinases, Molecular biology, Xenograft Model Antitumor Assays, 030104 developmental biology, Oncology, Colonic Neoplasms, Cancer research, Female, Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b269b8d8e2babc7c88b71cafcfdf84be
https://pubmed.ncbi.nlm.nih.gov/26637668