نتائج البحث - "Exercise Tolerance drug effects"

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رسالة جامعية

Mitochondrial efficiency : focus on dietary nitrate, hypoxia and exercise

مصطلحات موضوعية: Mitochondria -- drug effects, Mitochondria -- physiology, Nitrates -- administration & dosage, Nitrates -- metabolism, Nitrates -- pharmacology, Dietary Supplements, Basal Metabolism, Muscle, Skeletal -- drug effects, Muscle, Skeletal -- physiology, Anoxia, Calcium -- physiology, Exercise Tolerance -- drug effects, Electron Transport Complex IV -- metabolism

Degree: Diss. (sammanfattning) Stockholm : Karolinska Institutet, 2014

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Evaluation of Macitentan in Patients With Eisenmenger Syndrome Results From the Randomized, Controlled MAESTRO Study

المؤلفون: Gatzoulis, Michael A, Landzberg, Michael, Beghetti, Maurice, Berger, Rolf M, Efficace, Michela, Gesang, Sophie, He, Jian'guo, Papadakis, Kelly, Pulido, Tomás, Galiè, Nazzareno, MAESTRO Study Investigators

المساهمون: Cardiovascular Centre (CVC), Gatzoulis M.A., Landzberg M., Beghetti M., Berger R.M., Efficace M., Gesang S., He J., Papadakis K., Pulido T., Galie N.

المصدر: Circulation, 139(1), 51-63. LIPPINCOTT WILLIAMS & WILKINS
Circulation, Vol. 139, No 1 (2019) pp. 51-63

مصطلحات موضوعية: Male, macitentan, Time Factors, Down syndrome, 030204 cardiovascular system & hematology, EXERCISE CAPACITY, PULMONARY-ARTERIAL-HYPERTENSION, BOSENTAN THERAPY, chemistry.chemical_compound, DOUBLE-BLIND, 0302 clinical medicine, Peptide Fragment, Antihypertensive Agents/adverse effects/therapeutic use, pulmonary arterial hypertension, Natriuretic Peptide, Brain, Pulmonary Artery/drug effects/physiopathology, 030212 general & internal medicine, Child, Aged, 80 and over, Exercise Tolerance/drug effects, Exercise Tolerance, ddc:618, Down Syndrome/complications, Middle Aged, congenital heart disease, Shunting, CONGENITAL HEART-DISEASE, SILDENAFIL, Antihypertensive Agent, Treatment Outcome, Cardiology, SURVIVAL, Female, Sulfonamides/adverse effects/therapeutic use, Endothelin Receptor Antagonists/adverse effects/therapeutic use, Cardiology and Cardiovascular Medicine, Human, Eisenmenger Complex/complications/diagnostic imaging/physiopathology, medicine.drug, Adult, medicine.medical_specialty, Time Factor, Adolescent, Sildenafil, Hypertension, Pulmonary, TREPROSTINIL, Walk Test, Pulmonary Artery, Sulfonamide, Pyrimidines/adverse effects/therapeutic use, endothelin receptor antagonist, Young Adult, 03 medical and health sciences, Double-Blind Method, Physiology (medical), Internal medicine, INHALED ILOPROST, medicine, Humans, Hemodynamic, Aged, Macitentan, Endothelin receptor antagonist, business.industry, Eisenmenger syndrome, Biomarker, Recovery of Function, Eisenmenger Complex, medicine.disease, EFFICACY, Hypertension, Pulmonary/diagnostic imaging/drug therapy/etiology/physiopathology, Pulmonary hypertension, Hemodynamics/drug effects, Pyrimidine, chemistry, Natriuretic Peptide, Brain/blood, Peptide Fragments/blood, business, Biomarkers/blood, Treprostinil

وصف الملف: application/pdf; STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed441d34aa3a8f7a94367cf4a62011fb
https://doi.org/10.1161/circulationaha.118.033575

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Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in patients with mitochondrial myopathy

المؤلفون: Klaas Nicolay, Jeanine J. Prompers, Irenaeus F.M. de Coo, Carlijn M. P. le Clercq, Natal A. W. van Riel, Luc J. C. van Loon, Hubert J.M. Smeets, Joep P. J. Schmitz, Miranda Nabben, Stephan F. E. Praet, Harm R. Haak, Jolita Ciapaite

المساهمون: ACS - Microcirculation, Amsterdam Gastroenterology Endocrinology Metabolism, Experimental Vascular Medicine, Neurology, Rehabilitation Medicine, Moleculaire Genetica, RS: CARIM - R2.06 - Intermediate cardiac metabolism, RS: CAPHRI - R1 - Ageing and Long-Term Care, Interne Geneeskunde, RS: FHML MaCSBio, RS: GROW - R4 - Reproductive and Perinatal Medicine, RS: CARIM - R2.10 - Mitochondrial disease, Klinische Genetica, Bewegingswetenschappen, RS: NUTRIM - R3 - Respiratory & Age-related Health, RS: NUTRIM - HB/BW section A, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting, Computational Biology

المصدر: American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 312(5), R689-R701. American Physiological Society
American Journal of Physiology-Regulatory Integrative and Comparative Physi, 312(5), R689-R701. American Physiological Society
American Journal of Physiology-regulatory Integrative and Comparative Physiology, 312(5), R689-R701. American Physiological Society
American Journal of Physiology : Regulatory Integrative and Comparative Physiology, 312(5), R689-R701. American Physiological Society

مصطلحات موضوعية: 0301 basic medicine, Male, P-magnetic resonance spectroscopy, Mitochondrial Myopathies/drug therapy, Physiology, Administration, Oral, Muscle Strength/drug effects, Nitrate, Oxygen, SUPPLEMENTATION, Oxygen Consumption/drug effects, chemistry.chemical_compound, 0302 clinical medicine, Mitochondrial myopathy, Exercise Tolerance/drug effects, Exercise Tolerance, Permeabilized muscle fibers, Mitochondrial Myopathies, HUMAN SKELETAL-MUSCLE, Middle Aged, Nitrates/administration & dosage, Mitochondria, Treatment Outcome, RESPIRATION, Administration, INORGANIC NITRATE, Female, medicine.symptom, P-31-magnetic resonance spectroscopy, Oral, Adult, medicine.medical_specialty, EFFICIENCY, VO, chemistry.chemical_element, Exercise intolerance, Biology, V̇o2peak, Nitric oxide, 03 medical and health sciences, Young Adult, Oxygen Consumption, Physiology (medical), Internal medicine, 31P-magnetic resonance spectroscopy, Dietary Nitrate, Respiration, medicine, Humans, In patient, O-2 COST, Muscle/drug effects, Muscle Strength, Exercise, Aged, Nitrates, NITRIC-OXIDE, Muscle weakness, (V) over dot(O2peak), CONSUMPTION, medicine.disease, Mitochondria, Muscle, Mitochondria, Muscle/drug effects, 030104 developmental biology, Endocrinology, chemistry, TIME-TRIAL PERFORMANCE, Physical therapy, Psychomotor Performance/drug effects, Psychomotor Performance, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7a78142a4ad26aad57c0b95bb7ad73
https://doi.org/10.1152/ajpregu.00264.2016

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Evaluation of Macitentan in Patients With Eisenmenger Syndrome

المؤلفون: Gatzoulis, M.A., Landzberg, M., Beghetti, M., Berger, R.M., Efficace, M., Gesang, S., He, J., Papadakis, K., Pulido, T., Galiè, N.

المساهمون: MAESTRO Study Investigators

المصدر: Circulation, vol. 139, no. 1, pp. 51-63

مصطلحات موضوعية: Adolescent, Adult, Aged, Aged, 80 and over, Antihypertensive Agents/adverse effects, Antihypertensive Agents/therapeutic use, Biomarkers/blood, Child, Double-Blind Method, Down Syndrome/complications, Eisenmenger Complex/complications, Eisenmenger Complex/diagnostic imaging, Eisenmenger Complex/physiopathology, Endothelin Receptor Antagonists/adverse effects, Endothelin Receptor Antagonists/therapeutic use, Exercise Tolerance/drug effects, Female, Hemodynamics/drug effects, Humans, Hypertension, Pulmonary/diagnostic imaging, Hypertension, Pulmonary/drug therapy, Hypertension, Pulmonary/etiology, Hypertension, Pulmonary/physiopathology, Male, Middle Aged, Natriuretic Peptide, Brain/blood, Peptide Fragments/blood, Pulmonary Artery/drug effects, Pulmonary Artery/physiopathology, Pyrimidines/adverse effects, Pyrimidines/therapeutic use, Recovery of Function, Sulfonamides/adverse effects, Sulfonamides/therapeutic use, Time Factors, Treatment Outcome, Walk Test, Young Adult, Down syndrome, Eisenmenger syndrome, congenital heart disease, endothelin receptor antagonist, macitentan, pulmonary arterial hypertension

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1900::bfe35a2b36e413c7337ccb8cf1df5ac1
https://serval.unil.ch/notice/serval:BIB_2B3253EE0026

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Effect of 6 wk of high-intensity one-legged cycling on functional sympatholysis and ATP signaling in patients with heart failure

المؤلفون: Ulrik Winning Iepsen, Gregers Winding Munch, Jaya B. Rosenmeier, Bente Klarlund Pedersen, Camilla Koch Ryrsø, Stefan P. Mortensen

المصدر: Munch, G W, Iepsen, U W, Ryrsø, C K, Rosenmeier, J B, Pedersen, B K & Mortensen, S P 2018, ' Effect of 6 wk of high-intensity one-legged cycling on functional sympatholysis and ATP signaling in patients with heart failure ', American Journal of Physiology: Heart and Circulatory Physiology, vol. 314, no. 3, pp. H616-H626 . https://doi.org/10.1152/ajpheart.00379.2017

مصطلحات موضوعية: Male, Adenosine Triphosphate/administration & dosage, Sympathetic Nervous System, Time Factors, Physiology, Denmark, Vasodilator Agents, Vasodilation, 030204 cardiovascular system & hematology, Ventricular Function, Left, chemistry.chemical_compound, 0302 clinical medicine, Adenosine Triphosphate, Heart Failure/blood, Sympathomimetics, Exercise Tolerance/drug effects, Exercise Tolerance, High intensity, Stroke volume, Tyramine, Middle Aged, Exercise Therapy, Treatment Outcome, Lower Extremity, Sympathomimetics/administration & dosage, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, Cycling, Muscle contraction, Muscle Contraction, medicine.medical_specialty, Hyperemia, 03 medical and health sciences, Physiology (medical), Internal medicine, medicine, Training, Humans, In patient, Muscle, Skeletal, Aged, Heart Failure, Sympathetic Nervous System/drug effects, business.industry, Vasodilation/drug effects, Hyperemia/physiopathology, Stroke Volume, Vascular function, medicine.disease, Exercise Therapy/methods, Bicycling, Endocrinology, chemistry, Regional Blood Flow, Vasodilator Agents/administration & dosage, Heart failure, Muscle, Skeletal/blood supply, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a39823ce472b81f931c389e608a185c
https://pubmed.ncbi.nlm.nih.gov/29167117

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STARTS-2

المؤلفون: Irina Konourina, Robyn J. Barst, D. Dunbar Ivy, Tomás Pulido, Maurice Beghetti, Min Zhang, Gary Layton

المصدر: Circulation, Vol. 129, No 19 (2014) pp. 1914-23

مصطلحات موضوعية: Male, Pediatrics, Time Factors, Exercise Tolerance/drug effects/physiology, Hemodynamics/drug effects/physiology, Vasodilator Agents, Administration, Oral, Hemodynamics, Kaplan-Meier Estimate, Piperazines, chemistry.chemical_compound, Medicine, Familial Primary Pulmonary Hypertension, Sulfones, Child, ddc:618, Exercise Tolerance, Hazard ratio, Survival Rate, Treatment Outcome, Child, Preschool, Anesthesia, cardiovascular system, Regression Analysis, Female, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Adolescent, Sildenafil, Hypertension, Pulmonary, Placebo, Sildenafil Citrate, Double-Blind Method, Physiology (medical), Hypertension, Pulmonary/drug therapy/mortality/physiopathology, Humans, Purines/administration & dosage, Survival rate, Dose-Response Relationship, Drug, business.industry, Infant, Piperazines/administration & dosage, medicine.disease, Pulmonary hypertension, Confidence interval, respiratory tract diseases, Clinical trial, chemistry, Purines, Vasodilator Agents/administration & dosage, business, Sulfones/administration & dosage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afb5d82676502848b724d3c2d915cd1
https://doi.org/10.1161/circulationaha.113.005698

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SLC25A32 Mutations and Riboflavin-Responsive Exercise Intolerance

المؤلفون: Pierre Rustin, Alexander Tzagoloff, Norma B. Romero, Chen-Hsien Su, Malgorzata Rak, Christine Vianey-Saban, Hélène Smedts-Walters, Audrey Boutron, Odile Rigal, Hélène Ogier de Baulny, Manuel Schiff, Cécile Acquaviva-Bourdain, Alice Veauville-Merllié

المساهمون: Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA)

المصدر: New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2016, 374 (8), pp.795-7. ⟨10.1056/NEJMc1513610⟩

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Heterozygote, Adolescent, [SDV]Life Sciences [q-bio], Riboflavin, Exercise intolerance, medicine.disease_cause, Article, Skeletal/*pathology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Riboflavin/*therapeutic use, Internal medicine, medicine, Humans, heterocyclic compounds, ComputingMilieux_MISCELLANEOUS, Exercise Tolerance/drug effects/*genetics, Flavin adenine dinucleotide, Mutation, biology, Membrane Transport Proteins/deficiency/*genetics, business.industry, Membrane transport protein, Heterozygote advantage, Transporter, General Medicine, 3. Good health, 030104 developmental biology, Endocrinology, Biochemistry, chemistry, Mitochondrial Diseases/drug therapy/*genetics, biology.protein, Muscle, Female, medicine.symptom, business, Haploinsufficiency, 030217 neurology & neurosurgery