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المؤلفون: K Kollmann, W Warsch, C Gonzalez-Arias, F L Nice, E Avezov, J Milburn, J Li, D Dimitropoulou, S Biddie, M Wang, E Poynton, M Colzani, M R Tijssen, S Anand, U McDermott, B Huntly, T Green
المساهمون: Avezov, Edward [0000-0002-2894-0585], Huntly, Brian [0000-0003-0312-161X], Green, Tony [0000-0002-9795-0218], Apollo - University of Cambridge Repository
المصدر: Kollmann, K, Warsch, W, Gonzalez-Arias, C, Nice, F L, Avezov, E, Milburn, J, Li, J, Dimitropoulou, D, Biddie, S, Wang, M, Poynton, E, Colzani, M, Tijssen, M R, Anand, S, McDermott, U, Huntly, B & Green, T 2017, ' A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation ', Leukemia, vol. 31, no. 4, pp. 934-944 . https://doi.org/10.1038/leu.2016.280
Leukemiaمصطلحات موضوعية: Protein Stability, Thrombopoiesis/genetics, ras Proteins/genetics, Cell Differentiation, Megakaryocytes/cytology, Cell Line, Proteasome Endopeptidase Complex/metabolism, Fetal Blood/cytology, Janus Kinase 2/antagonists & inhibitors, Protein Kinase Inhibitors/pharmacology, Signal Transduction/drug effects, StemCellInstitute, Calreticulin/antagonists & inhibitors, Drug Discovery, Mutation, Proto-Oncogene Proteins B-raf/genetics, Humans, Ectopic Gene Expression/drug effects, Mitogen-Activated Protein Kinases/metabolism, Antigens, CD34/metabolism
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::64fc6363344fd1a5c016cf0ddbaeb804
https://www.repository.cam.ac.uk/handle/1810/261276 -
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المؤلفون: K, Kollmann, W, Warsch, C, Gonzalez-Arias, F L, Nice, E, Avezov, J, Milburn, J, Li, D, Dimitropoulou, S, Biddie, M, Wang, E, Poynton, M, Colzani, M R, Tijssen, S, Anand, U, McDermott, B, Huntly, T, Green
المصدر: Leukemia
مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Proteasome Endopeptidase Complex, Protein Stability, Antigens, CD34, Cell Differentiation, Janus Kinase 2, Fetal Blood, Cell Line, Ectopic Gene Expression, Thrombopoiesis, Drug Discovery, Mutation, ras Proteins, Humans, Original Article, Mitogen-Activated Protein Kinases, Calreticulin, Megakaryocytes, Protein Kinase Inhibitors, Signal Transduction
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