المؤلفون: Bruce HA; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Singer AU; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Blazer LL; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Luu K; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Ploder L; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Pavlenco A; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Kurinov I; NE-CAT, Cornell University, Argonne, Illinois, USA., Adams JJ; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Sidhu SS; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada.

المصدر: Protein science : a publication of the Protein Society [Protein Sci] 2024 Jul; Vol. 33 (7), pp. e5081.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Fab Fragments*/chemistry , Immunoglobulin Fab Fragments*/metabolism, Crystallography, X-Ray ; Crystallization ; Models, Molecular ; Protein Conformation ; Humans ; Amino Acid Substitution

المؤلفون: Lin HH; Institute of Chemistry, Academia Sinica, Taipei, Taiwan.; Institute of Statistical Science, Academia Sinica, Taipei, Taiwan., Wang CH; Institute of Chemistry, Academia Sinica, Taipei, Taiwan.; Academia Sinica Cryo-EM Facility, Academia Sinica, Taipei, Taiwan., Huang SH; Institute of Chemistry, Academia Sinica, Taipei, Taiwan.; Institute of Preventive Medicine, National Defense Medical Center, New Taipei City, Taiwan., Lin SY; Institute of Chemistry, Academia Sinica, Taipei, Taiwan., Kato T; Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka, Japan.; Institute of Protein Research, Osaka University, Suita, Osaka, Japan., Namba K; Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka, Japan., Hosogi N; JEOL Ltd., 1-2 Musashino 3-chome, Akishima, Tokyo, Japan., Song C; Exploratory Research Center on Life and Living Systems (ExCELLS) and National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences, 38 Nishigonaka Myodaiji, Okazaki, Aichi, Japan., Murata K; Exploratory Research Center on Life and Living Systems (ExCELLS) and National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences, 38 Nishigonaka Myodaiji, Okazaki, Aichi, Japan., Yen CH; Genomic Research Center, Academia Sinica, Taipei, Taiwan., Hsu TL; Genomic Research Center, Academia Sinica, Taipei, Taiwan., Wong CH; Genomic Research Center, Academia Sinica, Taipei, Taiwan., Wu YM; Institute of Chemistry, Academia Sinica, Taipei, Taiwan.; Cryo-EM Facility, College of Medicine, National Taiwan University, Taipei, Taiwan., Tu IP; Institute of Statistical Science, Academia Sinica, Taipei, Taiwan., Chang WH; Institute of Chemistry, Academia Sinica, Taipei, Taiwan. weihau40@gmail.com.; Genomic Research Center, Academia Sinica, Taipei, Taiwan. weihau40@gmail.com.; Institute of Physics, Academia Sinica, Taipei, Taiwan. weihau40@gmail.com.

المصدر: Scientific reports [Sci Rep] 2024 Jun 18; Vol. 14 (1), pp. 14079. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cryoelectron Microscopy*/methods , Immunoglobulin Fab Fragments*/chemistry , Immunoglobulin Fab Fragments*/ultrastructure , Immunoglobulin G*/chemistry , Protein Conformation*, Rituximab/chemistry ; Humans ; Models, Molecular

المؤلفون: Kolossov VL; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Holonyak Micro and Nanotechnology Laboratory, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States., Kanakaraju K; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States., Sarkar S; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Holonyak Micro and Nanotechnology Laboratory, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Department of Chemistry, Indian Institute of Technology Jodhpur, Rajasthan 342037, India., Arogundade OH; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Holonyak Micro and Nanotechnology Laboratory, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States., Kuo CW; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Holonyak Micro and Nanotechnology Laboratory, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States., Mara NR; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States., Smith AM; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Holonyak Micro and Nanotechnology Laboratory, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Department of Materials Science and Engineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.; Carle Illinois College of Medicine, Urbana, Illinois 61801, United States.

المصدر: ACS nano [ACS Nano] 2024 Jun 11; Vol. 18 (23), pp. 15084-15095. Date of Electronic Publication: 2024 May 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

مواضيع طبية MeSH: Quantum Dots*/chemistry , Immunoglobulin Fab Fragments*/chemistry , Immunoglobulin Fab Fragments*/immunology , Microtubules*/chemistry , Microtubules*/metabolism, Humans ; Animals ; Mice ; Fluorescent Dyes/chemistry

المؤلفون: Fiala J; Biomolecular Mass Spectrometry & Proteomics, Bijvoet Center for Biomolecular Research & Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., Schuster D; Biomolecular Mass Spectrometry & Proteomics, Bijvoet Center for Biomolecular Research & Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., Ollivier S; Biomolecular Mass Spectrometry & Proteomics, Bijvoet Center for Biomolecular Research & Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., Pengelley S; Bruker Daltonics GmbH & Co. KG, Fahrenheitstrasse 4, 28359 Bremen, Germany., Lubeck M; Bruker Daltonics GmbH & Co. KG, Fahrenheitstrasse 4, 28359 Bremen, Germany., Busch F; Bruker Switzerland AG, 8117 Fällanden, Zurich Switzerland., Jankevics A; Biomolecular Mass Spectrometry & Proteomics, Bijvoet Center for Biomolecular Research & Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., Raether O; Bruker Daltonics GmbH & Co. KG, Fahrenheitstrasse 4, 28359 Bremen, Germany., Greisch JF; Bruker Switzerland AG, 8117 Fällanden, Zurich Switzerland., Heck AJR; Biomolecular Mass Spectrometry & Proteomics, Bijvoet Center for Biomolecular Research & Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands.

المصدر: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2024 Jun 05; Vol. 35 (6), pp. 1292-1300. Date of Electronic Publication: 2024 Apr 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 9010412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1123 (Electronic) Linking ISSN: 10440305 NLM ISO Abbreviation: J Am Soc Mass Spectrom Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Fab Fragments*/chemistry , Immunoglobulin Fab Fragments*/analysis , Immunoglobulin Fab Fragments*/blood , Proteomics*/methods , Mass Spectrometry*/methods, Humans ; Chromatography, Liquid/methods ; Immunoglobulin G/blood ; Immunoglobulin G/chemistry ; Immunoglobulin G/analysis ; Precision Medicine/methods ; Liquid Chromatography-Mass Spectrometry

المؤلفون: Stern D; Biological Toxins (ZBS 3), Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin 13353, Germany., Dettmann P; Biological Toxins (ZBS 3), Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin 13353, Germany., Dorner BG; Biological Toxins (ZBS 3), Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin 13353, Germany., Mages HW; Biological Toxins (ZBS 3), Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin 13353, Germany. Electronic address: magesh@rki.de.

المصدر: Journal of immunological methods [J Immunol Methods] 2024 Jun; Vol. 529, pp. 113669. Date of Electronic Publication: 2024 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1305440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7905 (Electronic) Linking ISSN: 00221759 NLM ISO Abbreviation: J Immunol Methods Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Fab Fragments*/isolation & purification , Immunoglobulin Fab Fragments*/immunology , Immunoglobulin Fab Fragments*/chemistry , Chromatography, Affinity*/methods, Humans ; Animals ; Mice ; HEK293 Cells ; Bacterial Proteins/isolation & purification ; Bacterial Proteins/immunology ; Bacterial Proteins/chemistry

المؤلفون: Waibel S; Department of Urology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Graf N; Department of Urology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Storz J; Institute for Organic Chemistry, University of Freiburg, Freiburg, Germany., Schultze-Seemann S; Department of Urology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lauw S; Core Facility Signalling Factory & Robotics, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany., Gratzke C; Department of Urology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Brückner R; Institute for Organic Chemistry, University of Freiburg, Freiburg, Germany., Wolf P; Department of Urology, Medical Center - University of Freiburg, Freiburg, Germany; philipp.wolf@uniklinik-freiburg.de.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Wolf I; Department of Urology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.

المصدر: Anticancer research [Anticancer Res] 2024 Jun; Vol. 44 (6), pp. 2343-2348.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Internet ISSN: 1791-7530 (Electronic) Linking ISSN: 02507005 NLM ISO Abbreviation: Anticancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Fab Fragments*/immunology , Immunoglobulin Fab Fragments*/chemistry , Immunoglobulin Fab Fragments*/pharmacology , Prostatic Neoplasms*/therapy , Prostatic Neoplasms*/radiotherapy , Prostatic Neoplasms*/pathology , Immunotherapy*/methods , Antigens, Surface*/immunology , Antigens, Surface*/metabolism, Humans ; Male ; Cell Line, Tumor ; Glutamate Carboxypeptidase II/immunology ; Glutamate Carboxypeptidase II/metabolism ; Photosensitizing Agents/pharmacology ; Photosensitizing Agents/therapeutic use ; Phototherapy/methods ; Antibodies, Monoclonal, Humanized/pharmacology ; Antibodies, Monoclonal, Humanized/therapeutic use

المؤلفون: Clarke JD; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Douangamath A; Macromolecular Crystallography, Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom., Mikolajek H; Macromolecular Crystallography, Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom., Bonnet-Di Placido M; Immunogenetics, The Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, United Kingdom., Ren J; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Fry EE; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Stuart DI; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Hammond JA; Immunogenetics, The Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, United Kingdom., Owens RJ; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom.

المصدر: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2024 Jul 01; Vol. 80 (Pt 7), pp. 154-163. Date of Electronic Publication: 2024 Jul 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Inc Country of Publication: United States NLM ID: 101620319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2053-230X (Electronic) Linking ISSN: 2053230X NLM ISO Abbreviation: Acta Crystallogr F Struct Biol Commun Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Heavy Chains*/chemistry , Immunoglobulin Light Chains*/chemistry , Immunoglobulin Light Chains*/genetics , Complementarity Determining Regions*/chemistry , Immunoglobulin Fab Fragments*/chemistry , Models, Molecular*, Animals ; Cattle ; Crystallography, X-Ray ; Amino Acid Sequence ; Protein Conformation

المؤلفون: Rathore Y; From the Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh., Lakhanpal T; From the Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh., Chakraborty S, Chakravarty R, Mittal BR; From the Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh., Irrinki RNS; Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Laroiya I; Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Kaur K; From the Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh., Shukla J; From the Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh.

المصدر: Clinical nuclear medicine [Clin Nucl Med] 2024 Jun 01; Vol. 49 (6), pp. e258-e265. Date of Electronic Publication: 2024 Apr 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Country of Publication: United States NLM ID: 7611109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-0229 (Electronic) Linking ISSN: 03639762 NLM ISO Abbreviation: Clin Nucl Med Subsets: MEDLINE

مواضيع طبية MeSH: Trastuzumab*/pharmacology , Trastuzumab*/pharmacokinetics , Trastuzumab*/chemistry , Breast Neoplasms*/diagnostic imaging , Breast Neoplasms*/drug therapy , Lutetium* , Isotope Labeling* , Immunoglobulin Fab Fragments* , Radioisotopes*, Humans ; Female

المؤلفون: Giraud A; Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), 71, Avenue des Martyrs, 38044, Grenoble, France.; Sanofi Research & Development, 94403, Vitry-sur-Seine, France.; NMR-Bio, 5 place Robert Schuman, 38025, Grenoble, France., Imbert L; Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), 71, Avenue des Martyrs, 38044, Grenoble, France., Favier A; Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), 71, Avenue des Martyrs, 38044, Grenoble, France., Henot F; Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), 71, Avenue des Martyrs, 38044, Grenoble, France.; Sanofi Research & Development, 94403, Vitry-sur-Seine, France., Duffieux F; Sanofi Research & Development, 94403, Vitry-sur-Seine, France., Samson C; Sanofi Research & Development, 94403, Vitry-sur-Seine, France., Frances O; Sanofi Research & Development, 94403, Vitry-sur-Seine, France. Oriane.Frances@sanofi.com., Crublet E; NMR-Bio, 5 place Robert Schuman, 38025, Grenoble, France. crublet@nmr-bio.com., Boisbouvier J; Univ. Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale (IBS), 71, Avenue des Martyrs, 38044, Grenoble, France. jerome.boisbouvier@ibs.fr.

المصدر: Journal of biomolecular NMR [J Biomol NMR] 2024 Jun; Vol. 78 (2), pp. 73-86. Date of Electronic Publication: 2024 Mar 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 9110829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-5001 (Electronic) Linking ISSN: 09252738 NLM ISO Abbreviation: J Biomol NMR Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Fab Fragments*/chemistry , Nuclear Magnetic Resonance, Biomolecular*/methods , Isotope Labeling*/methods, Humans ; Cell-Free System ; Nitrogen Isotopes ; Antibodies, Monoclonal/chemistry

المؤلفون: Petersen BM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Kirby MB; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Chrispens KM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Irvin OM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Strawn IK; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Haas CM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Walker AM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Baumer ZT; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Ulmer SA; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Ayala E; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Rhodes ER; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Guthmiller JJ; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Steiner PJ; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA., Whitehead TA; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, USA. timothy.whitehead@colorado.edu.

المصدر: Nature communications [Nat Commun] 2024 May 10; Vol. 15 (1), pp. 3974. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Fab Fragments*/genetics , Immunoglobulin Fab Fragments*/chemistry , Immunoglobulin Fab Fragments*/immunology , Mutation* , High-Throughput Nucleotide Sequencing*/methods, Humans ; Protein Engineering/methods ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/chemistry ; Antibodies, Neutralizing/genetics ; Complementarity Determining Regions/genetics ; Complementarity Determining Regions/chemistry ; Antibody Affinity ; Antigens/immunology ; Antigens/genetics