المؤلفون: Koshkina, Nadya^Aff8, Yang, Yuanzheng^Aff8, Kleinerman, Eugenie S.^Aff8

المساهمون: Crusio, Wim E., Series Editor^Aff1, Dong, Haidong, Series Editor^Aff2, Lambris, John D., Series Editor^Aff3, Radeke, Heinfried H., Series Editor^Aff4, Rezaei, Nima, Series Editor^Aff5, Kleinerman, Eugenie S., editor^Aff6, Gorlick, Richard, editor^Aff7

المصدر: Current Advances in the Science of Osteosarcoma : Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models. 1258:177-187

المؤلفون: Antônio Rafael Quadros Gomes, Ana Laura Gadelha Castro, Kelly Cristina Oliveira de Albuquerque, Sandro Percário, Valdicley Vieira Vale, Heliton Patrick Cordovil Brígido, Rommel Rodríguez Burbano, Liliane Almeida Carneiro, Marcelo de Oliveira Bahia, Natasha Costa da Rocha Galucio, Fábio Alberto de Molfeta, Everton Luiz Pompeu Varela, Maria Fâni Dolabela

المصدر: Toxicology Reports, Vol 8, Iss, Pp 1480-1487 (2021)
Toxicology Reports

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, BFS, bovine fetal serum, AST, aspartate aminotransferase, DMSO, dimethyl sulfoxide, Pharmacology, Toxicology, medicine.disease_cause, EDTA, ethylenediaminetetraacetic, OECD, Organization for Economic Co-Operation and Development, RA1190-1270, Eleutherin, FDMEp, dichloromethane fraction of Eleutherine plicata, BCRJ, Cell bank of Rio de Janeiro, MTT, ([3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide]), Cytotoxicity, RPMI, Roswell Park Memorial Institute medium, DPPH, 2,2-diphenyl-1-picrylhydrazyl, Eleutherine, biology, Chemistry, Regular Article, TLC, tin layer chromatography, EEEp, ethanol extract of Eleutherine plicata, MD, molecular dynamics, TNFR, tumour necrosis fator receptor, HPLC, high performance liquid chromatography, Toxicity, DNA fragmentation, GOLD, Genetic Optimization for Ligand Docking, medicine.symptom, Caspase-8, IC50, 50 % cytotoxic concentration, DARP, dopamine releasing protein, Isoeleutherin, rpm, rotations per minute, DMEM, Dulbecco's Modified Eagle's Medium, ROS, reactive oxygen species, PDB, Protein Data Bank, ALT, alanine aminotransferase, FrAE, ethyl acetate fraction of Elutherine plicata, medicine, NMR, nuclear magnetic resonance, ComputingMethodologies_COMPUTERGRAPHICS, Eleutherine plicata, FADD, Fas associated death domain, GA, Genetic Algorithm, biology.organism_classification, RSMD, root mean square deviation, In vitro, NMU, N-methyl-N-nitrosurea, Eleutherol, Comet assay, Mechanism of action, Toxicology. Poisons, Genotoxicity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203384ee56884c6277fc2f84190f3cdf
https://doi.org/10.1016/j.toxrep.2021.07.015

المؤلفون: Yun Ju Lee, Minju Hyun, Kwang Chul Chung, Sungyeon Jung, Su Hyoun Lee

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: PEI, polyethylenimine, Male, HEK293, human embryonic kidney 293, Cell Cycle Proteins, ECL, enhanced chemiluminescence, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, Mice, caspase 8, DISC, death-inducing signaling complex, FADD, FAS-associated death domain, Mitophagy, FADD, Caspase, Neurons, 6-OHDA, 6-hydroxydopamine, biology, Chemistry, MPP+, 1-methyl-4-phenylpyridium ion, FOXO4, HRP, horseradish peroxidase, FOXO Family, Forkhead Transcription Factors, Parkinson Disease, Cell biology, Ubiquitin ligase, Death-inducing signaling complex, MCF-7 Cells, AD, Alzheimer's disease, Ubl, ubiquitin-like, Research Article, 6-OHDA, X-IAP, X-linked IAP, Caspase 8, PRR, proline-rich region, ROS, reactive oxygen species, FBS, fetal bovine serum, UPS, ubiquitin-proteasome system, Animals, Humans, FBXO7, Molecular Biology, PD, Parkinson’s disease, SCF, SKP1-Cullin1-F-box, NDDs, neurodegenerative diseases, TRAIL, TNF-related apoptosis-inducing ligand, neuronal cell death, F-Box Proteins, FBXO7, F-box only protein 7, Cell Biology, HEK293 Cells, Proteasome, Proteolysis, Parkinson’s disease, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069a47280d03b89b5c0f58a2dcb15dca
https://doi.org/10.1016/j.jbc.2021.101426

المؤلفون: Chung Yong Kim, Yoon Jun Kim, Jung Hwan Yoon, Su Jong Yu, Jeong Hoon Lee, Minjong Lee, Yuri Cho, Jeong-Ju Yoo, Dong Hyeon Lee, Eun Ju Cho

المصدر: Acta Pharmaceutica Sinica B, Vol 5, Iss 6, Pp 544-553 (2015)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: MAPK/ERK pathway, Hepatocellular carcinoma, NDRG, N-myc downstream-regulated gene, chemistry.chemical_compound, DNA, deoxyribonucleic acid, PCR, polymerase chain reaction, DISC, death-inducing signaling complex, VMP, vacuole membrane protein, Invasion, FADD, MTS, 3,4-(5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium salt, General Pharmacology, Toxicology and Pharmaceutics, Hypoxia, DMEM, Dulbecco׳s modified Eagle׳s medium, WME, William's medium E, biology, Fucoidan, SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, NDRG-1/CAP43, ELISA, enzyme-linked immunosorbent assay, Hepatoprotective, medicine.anatomical_structure, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, BA, bile acid, Original Article, VMP-1, IHC, immunohistochemistry, Cultured hepatocyte, Spleen, cDNA, complementary DNA, FBS, fetal bovine serum, CXCL, chemokine ligand, In vivo, medicine, JNK, c-Jun NH2-terminal kinase, Death domain, FADD, Fas associated death domain, GP, glypican, lcsh:RM1-950, Molecular biology, In vitro, lcsh:Therapeutics. Pharmacology, chemistry, siRNA, small interfering RNA, Apoptosis, RNA, ribonucleic acid, Cancer research, biology.protein, FCS, fetal calf serum, HCC, hepatocellular carcinoma, SD, standard deviation, MAPK, mitogen-activated protein kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1b87af69d8fa9246f89bc5aef0e562
http://www.sciencedirect.com/science/article/pii/S2211383515001367

المؤلفون: Kazuhiro Sakamaki, Chisa Shukunami, Kentaro Tomii, Naoto Ueno, Hiroaki Iwata, Kumiko Chiba, Chiyo Takagi, Kenichiro Imai, Naoyuki Iwabe

المصدر: Biochemistry and Biophysics Reports

مصطلحات موضوعية: Subfamily, RT-PCR, reverse transcription-polymerase chain reaction, Evolution, Mutant, Biophysics, Xenopus, Apoptosis, Biochemistry, NF-κB, CFLAR, CASc, Caspase, interleukin-1 β converting enzyme homologs, tubα6, tubulin α6, Protein structure, PCR, polymerase chain reaction, CHX, cycloheximide, biology.animal, CARD, caspase-recruitment domain, DED, death effector domain, MO, morpholino oligonucleotide, Zebrafish, TRAF2, tumor necrosis factor receptor-associated factor 2, Pseudocatalytic triad, Genetics, Protein subfamily, biology, Vertebrate, NF-κB, Nuclear factor-kappa B, biology.organism_classification, FADD, Fas-associated death domain protein, c-FLIP, cellular FLICE-like inhibitory protein, EGFP, enhanced green fluorescent protein, ODC, ornithine decarboxylase, Embryogenesis, Caspase-8, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1affca1a95815da2e31ef14cbfe098c1
http://hdl.handle.net/2433/199933

المؤلفون: Graeme Nixon, Fiona H. Greig

المصدر: Pharmacology & Therapeutics

مصطلحات موضوعية: TRAIL, tumour necrosis factor-related apoptosis-inducing ligand, Protein Conformation, Proliferation, MAP, mitogen-activated protein, Apoptosis, Bioinformatics, PDGF, platelet-derived growth factor, CaMKII, calcium/calmodulin-dependent protein kinase II, Neoplasms, PEA-15, phosphoprotein enriched in astrocytes-15, RSK, ribosomal s6 kinase, Medicine, Pharmacology (medical), FADD, DED, death effector domain, Cancer, Brain Diseases, ERK1/2, extracellular signal-regulated kinases 1/2, ERK1/2, biology, Kinase, Intracellular Signaling Peptides and Proteins, food and beverages, Type 2 diabetes, PEA-15, GLUT, glucose transporter, Cell biology, Cardiovascular Diseases, TGF-β1, transforming growth factor-β1, Phosphorylation, Death effector domain, Associate editor: S. Kennedy, HNF-4α, hepatocyte nuclear factor 4alpha, Endocrine System Diseases, NSCLC, non-small cell lung cancer, Ca2+/calmodulin-dependent protein kinase, PKC, protein kinase C, Animals, Humans, PLD1, phospholipase D1, Protein kinase C, Death domain, Pharmacology, DISC, death initiation signalling complex, business.industry, Phosphoproteins, FADD, Fas-associated death domain protein, IL, interleukin, Phosphoprotein, VSM, vascular smooth muscle, biology.protein, Apoptosis Regulatory Proteins, PCOS, polycystic ovary syndrome, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd51792c95b568dbc8829ce0ba4c22fd
https://doi.org/10.1016/j.pharmthera.2014.03.006

المؤلفون: Joerg Stetefeld, Joanna Rzeszowska-Wolny, Mayur V. Jain, Artur Cieślar-Pobuda, Wiem Chaabane, Saeid Ghavami, Marek J. Łos, Mohamed El-Gazzah, Mehrdad Rafat

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 9, Pp 679-693 (2014)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Cytoplasm, Cancer Research, TMRM, Tetramethylrhodamine methyl ester perchlorate0, HGV-Apoptin, Human gyrovirus apoptin, Apoptosis, MOMP, Mitochondrial outer membrane permeabilization, Mitochondrial apoptosis-induced channel, AIF, Nur77, Annan medicinsk grundvetenskap, AIF, Apoptosis inducing factor, Nuclear Receptor Subfamily 4, Group A, Member 1, Gyrovirus, BCL-XL, B-cell lymphoma extra-large, DISC, Death-inducing signal complex, FADD, Other Basic Medicine, Membrane Potential, Mitochondrial, biology, Apoptosis Inducing Factor, Cytochromes c, virus diseases, Receptors, Death Domain, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, mitochondrial pathway, Mitochondria, Cell biology, Protein Transport, Proto-Oncogene Proteins c-bcl-2, Caspases, Apoptosis-inducing factor, Signal Transduction, CAV-Apoptin, Chicken anemia virus apoptin, Programmed cell death, cyt c, cytochrome c, caspase, Bcl-xL, Models, Biological, lcsh:RC254-282, Article, Cell Line, Viral Proteins, death receptors, Humans, 7AAD, 7-amino-actinomycin D, FADD, Fas-associated death domain, Death domain, Intrinsic apoptosis, MEF, Mouse embryonic fibroblast, cytc, digestive system diseases, Apoptin, biology.protein, Apoptosome

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff91e1764b6bc1727600d6c646b3f55
https://doi.org/10.1016/j.neo.2014.08.001

المؤلفون: Tadaaki Miyazaki, Takuya Shiozaki, Atsushi Iwai

المصدر: Biochemical and Biophysical Research Communications

مصطلحات موضوعية: Akt, v-akt murine thymoma viral oncogene homolog 1, Bcl-2, B-cell lymphoma 2, viruses, Apoptosis, Signal transduction, Virus Replication, medicine.disease_cause, Biochemistry, TRAIL, TNF-related apoptosis inducing ligand, DEAD-box RNA Helicases, Apaf-1, apoptotic protease activating factor 1, DAP3, death-associated protein 3, Influenza A virus, NS1, non-structural protein 1, Receptors, Immunologic, RIG-I, retinoic acid-inducible gene-I, Bax, Bcl-2-associated x protein, NP, nucleoprotein, TNF-α, tumor necrosis factor α, IPS-1, INF-β promoter stimulator protein 1, PI3K, phosphatidylinositol-3 kinase, XIAP, X-linked inhibitor of apoptosis protein, Caspase 3, RIG-I, Receptors, Death Domain, NA, neuraminidase, BH, Bcl-2 homology, XIAP, Cell biology, DEAD Box Protein 58, IRF3, IFN regulatory factor 3, Biophysics, NF-κB, nuclear factor-κB, TRADD, tumor necrosis factor receptor type 1-associated death domain protein, Biology, Article, Virus, DR5, death receptor 5, TNFαR1, TNF-α receptor 1, Caspases, cysteine–aspartic acid protease, IAV, influenza A virus, medicine, Humans, IFN, interferon, Molecular Biology, PI3K/AKT/mTOR pathway, FADD, Fas-associated death domain, DAP3, M, matrix protein, Cell Biology, JNK, c-Jun amino-terminal kinase, DR4, death receptor 4, ZAPS, zinc finger antiviral protein, short form

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f0da48e068b451f4a7e03370c91af3
https://doi.org/10.1016/j.bbrc.2013.10.100

المؤلفون: Hye Ryung Kim, Keon Hee Yoo, Hye Lim Jung, Dae Seong Kim, Soo Hyun Lee, Ki Woong Sung, Hee Won Chueh, Hong Hoe Koo, Ha Yeong Jo, Myoung Woo Lee

المصدر: Cell Biology International Reports

مصطلحات موضوعية: Programmed cell death, S1, Necrosis, PARP, poly(ADP-ribose) polymerase, AzaC, 5-aza-2′ deoxycytidine, IFNγ, interferon γ, TRAIL, inferferon γ, Caspase 8, S2, etoposide, TNF, tumour necrosis factor, caspase 8, FBS, fetal bovine serum, DR5, death receptor 5, medicine, Etoposide, Caspase, FADD, Fas-associated death domain, TRAIL, TNF-related apoptosis-inducing ligand, biology, Chemistry, DD, death domain, Cell Biology, BCA, bicinchoninic acid, Hedgehog signaling pathway, Apoptosis, Immunology, mitochondrial cascade, DcR, decoy receptor, Cancer research, biology.protein, death receptor, Tumor necrosis factor alpha, NF-κB, nuclear factor κB, medicine.symptom, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95b41cdb468401f5e9201be80af75f8
https://doi.org/10.1042/cbr20110008

المؤلفون: Hedger, M.P.

المصدر: Comprehensive Toxicology

مصطلحات موضوعية: lymphocytes, steroidogenesis, Tr1, T regulatory 1, NK, cell natural killer cell, LH, luteinizing hormone, MAP, mitogen-activated protein, Jak/Stat, Janus kinase/signal transducers and activators of transcription, 16:0a-LPC, 1-palmitoyl-sn-glycero-3-phosphocholine, TRADD, TNFR-associated death domain protein, MIF, macrophage migration inhibitory factor, Leydig cell, Aire, autoimmune regulator, TRAF, tumor necrosis factor receptor-associated factor, 18:1a-LPC, 1-oleoyl-sn-glycero-3-phosphocholine, GC, glucocorticoid, TGF, transforming growth factor, Crry, complement receptor-related protein, NLR, Nod-like receptor, P450scc, cholesterol side-chain cleavage complex, StAR, steroidogenic acute regulatory, TNF, tumor necrosis factor, TCR, T cell receptor, PGES, PGE synthase, Th cell, helper T cell, AID, acquired immune deviation, Sertoli cell, macrophages, LPC, lysoglycerophosphatidylcholine, EDS, ethane dimethane sulfonate, nNOS, neuronal NOS, iNOS, inducible nitric oxide synthase, TxAS, thromboxane A synthase, LPS, lipopolysaccharide, RIG, retinoic acid-inducible gene, hCG, human chorionic gonadotropin, TNFR, TNF receptor, PAMP, pathogen-associated molecular pattern, TLR, Toll-like receptor, Tx, thromboxane, immunoregulation, IFNAR, IFNα receptor, TIR, Toll/IL1R, PMN, polymorphonuclear phagocyte, Treg, regulatory T cell, IL1ra, IL1 receptor antagonist, sperm, Article, ROS, reactive oxygen species, nitric oxide, MyD88, myeloid differentiation primary response protein 88, AP1, activated protein 1, eNOS, endothelial NOS, Nod, nucleotide binding oligomerization domain, MHC, major histocompatibility complex, IFN, interferon, PG, prostaglandin, PAF, platelet-activating factor, prostanoids, HLA, human leukocyte antigen, EAO, experimental autoimmune orchitis, HMGB1, high mobility group box chromosomal protein 1, PLA2, phospholipase A2, PGI, prostacyclin, BMP, bone morphogenetic protein, CTL, cytotoxic T lymphocyte, FADD, Fas-associated death domain protein, immunity, cytokines, spermatogenesis, IL, interleukin, TRIF, TIR domain-containing adaptor protein inducing interferon β, COX, cyclooxygenase, PPARγ, peroxisome proliferator-activated receptor γ, 20:4a-LPC, 1-arachidonyl-sn-glycero-3-phosphocholine, FasL, Fas ligand, Jnk, Jun N-terminal kinase, toll-like receptors, APC, antigen-presenting cell, inflammation, RLH, RIG-like helicase, NFκB, nuclear factor kappa B, seminal plasma, P450c17, 17α-hydroxylase/C17-C20 lyase, FSH, follicle-stimulating hormone, BAMBI, BMP and activin membrane-bound inhibitor, 18:2a-LPC, 1-linoleoyl-sn-glycero-3-phosphocholine, ICE, IL1 converting enzyme, NKT cell, natural killer T cell, IL1R, interleukin 1 receptor, IRF, interferon regulatory factor, PC, phosphocholine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmc_________::680ec81c55542842993ec1979cf46ed0
http://europepmc.org/articles/PMC7099659