المؤلفون: Rubén López-Aladid, Luis Izquierdo, Francisco Carmona-Torre, Gemma Moncunill, Ruth Aguilar, Antoni Torres, Carlo Carolis, Natalia Rodrigo Melero, Matija Popovic, Alberto L. García-Basteiro, Alfredo Mayor, Jordi Chi, Laia Fernández-Barat, Marta Vidal, Carlota Dobaño, Alfons Jiménez, Marta Tortajada, Gabriel Reina, Rebeca Santano

المصدر: Translational Research

مصطلحات موضوعية: Male, 0301 basic medicine, MFI, median fluorescence intensity, Rhinovirus, viruses, LOESS, locally estimated scatterplot smoothing, Antibodies, Viral, medicine.disease_cause, 0302 clinical medicine, Seroepidemiologic Studies, FL, full-length, skin and connective tissue diseases, COVID-19, coronavirus disease 2019, biology, Immunogenicity, RBD, receptor-binding domain, virus diseases, Common cold, General Medicine, CT, C-terminus, 030220 oncology & carcinogenesis, ADE, antibody-dependent disease enhancement, Female, Antibody, S, spike, Alpha (ethology), Cross Reactions, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Article, rRT-PCR, real-time reverse-transcriptase polymerase chain reaction, NT, N-terminus, 03 medical and health sciences, Immunity, Physiology (medical), medicine, Coronavirus Nucleocapsid Proteins, Humans, Seroprevalence, Biochemistry, medical, SARS-CoV-2, M, month, fungi, Biochemistry (medical), Public Health, Environmental and Occupational Health, COVID-19, HCoV, common cold human coronavirus, medicine.disease, Virology, body regions, 030104 developmental biology, Immunoglobulin G, biology.protein, N, nucleocapsid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45628ce6fe9565dc99d05d6b5cfa0232
https://doi.org/10.1016/j.trsl.2021.02.006

المؤلفون: Chun Guo, Christopher Rood, Jian Li, Jinsong Zhang

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: IP4, inositol tetraphosphate, Conformational change, deacetylase-activation domain, HDAC, histone deacetylase, Biochemistry, Histone Deacetylases, conformational change, Protein Domains, Transcription (biology), FL, full-length, SANT, SWI3, ADA2, N-CoR or SMRT, and TFIIIB homology domain, Neoplasms, medicine, TSA, trichostatin A, Humans, SMRT, silencing mediator of retinoic acid and thyroid hormone receptor, Molecular Biology, Chemistry, C-terminus, HDAC3, Cell Biology, C terminus, DAD, deacetylase-activation domain, Cell biology, Neoplasm Proteins, Enzyme Activation, HDLP, a histone deacetylase–like protein, Trichostatin A, HEK293 Cells, Nuclear receptor, NCoR, nuclear receptor corepressor, Histone deacetylase, Signal transduction, Co-Repressor Proteins, medicine.drug, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c2fa0a0fef5e2df0798785326bc631
http://europepmc.org/articles/PMC8502911

المؤلفون: Robert N. Cole, Simion Kreimer, Santosh Renuse, Anil K. Madugundu, Robert N. O'Meally, Raiha Tahir, Natasha E. Zachara, Akhilesh Pandey, Raja Sekhar Nirujogi, Peter S. Natov, Marissa Martinez

المصدر: Molecular & Cellular Proteomics : MCP

مصطلحات موضوعية: Proteomics, Special Issue: Glycoproteomics, Glycosylation, TNKS1BP1, 182-kDa tankyrase-1–binding protein, GFAT, glutamine-fructose-6-phosphate transaminase, HSF1, heat shock factor protein 1, Network, Biochemistry, Interactome, Analytical Chemistry, Serine, chemistry.chemical_compound, eIF3b, eukaryotic translation initiation factor 3 subunit B, Mice, CARM1, coactivator-associated arginine methyltransferase 1, Stable isotope labeling by amino acids in cell culture, PRM, parallel reaction monitoring, 4MU, 4-methylumbelliferyl, O-GlcNAc, O-linked N-acetyl-β-D-glucosamine, Protein Interaction Maps, HSF1, Cells, Cultured, Host cell factor C1, 0303 health sciences, 030302 biochemistry & molecular biology, MEFs, mouse embryonic fibroblasts, Cell biology, HDAC1, histone deacetylase 1, H2O2, hydrogen peroxide, Bag6, large proline-rich protein BAG6, Null, OGT KO, TEABC, triethylammonium bicarbonate, CARM1, Quantitative proteomics, N-Acetylglucosaminyltransferases, HCF-1, host cell factor 1, FL, full length, 03 medical and health sciences, UAP1, UDP-N-acetylhexosamine pyrophosphorylase, Animals, SETD1A, histone-lysine N-methyltransferase SETD1A, TBST, Tris-buffered saline with Tween-20, Molecular Biology, 030304 developmental biology, TCL, total cell lysis, Research, SILAC, stable isotopic labeling of amino acids in cell culture, OGT, O-GlcNAc transferase, Fibroblasts, FOXO, daf-16, forkhead box protein O, TPR, tetratricopeptide repeats, Oxidative Stress, chemistry, Cytoprotection, OGA, O-GlcNAcase, CKII, casein kinase II

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b16ac4fff964cbea1b8e4cd43457fd
http://europepmc.org/articles/PMC8079276

المؤلفون: Samman Mansoor, Abdul-Rahman Khrbtli, Ozge Sensoy, Cameron Lee Shetler, Juliana C. Ferreira, Liaqat Ali, Wael M. Rabeh

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, CID, collision-induced dissociation, Linker Residues, cancer metabolism, Regulatory site, v, initial rate, Biochemistry, HK2, hexokinase-2, PME, particle mesh Ewald, Substrate Specificity, chemistry.chemical_compound, t1/2, half-life, DSC, differential scanning calorimetry, FL, full-length, Hexokinase, Enzyme Stability, G6P, glucose-6-phosphate, Enzyme Inhibitors, Tm, melting temperature, Promising Anticancer Target, biology, Chemistry, HKDC1, MD, molecular dynamics, CTD, C-terminal domain, enzyme inactivation, VDAC, voltage-dependent anion channel, HDX-MS, hydrogen/deuterium exchange mass spectrometry, Glycolysis, Research Article, Voltage-dependent anion channel, Antineoplastic Agents, DSF, differential scanning fluorimetry, Isozyme, Catalysis, 03 medical and health sciences, Protein Domains, Cell Line, Tumor, RMSF, root mean-square fluctuations, Humans, and anticancer therapeutics, KGlu, Michaelis constant for glucose, NTD, N-terminal domain, KATP, Michaelis constant for ATP, Molecular Biology, PCA, principal component analysis, 030102 biochemistry & molecular biology, ΔHcal, calorimetric enthalpy, HKDC1, hexokinase domain containing 1, Cell Biology, HK, hexokinase, Kinetics, 030104 developmental biology, Glucose 6-phosphate, Structural biology, biology.protein, Warburg effect, HIK, heat inactivation kinetics, Linker, cv, column volumes

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9776c595be3543717cc8dd8780d68291
https://pubmed.ncbi.nlm.nih.gov/33187984

المؤلفون: Bushra Rahman, Ehtesham Arif, Pei Wen, Zhe Han, Joshua H. Lipschutz, Avinash Singh, Sang Ho Kwon, Deepak Nihalani, Glenn P. Lobo, Pankaj Srivastava, Ashish K. Solanki, Wayne R. Fitzgibbon, Milos N. Budisavljevic, Christopher M. Furcht, Lawrence B. Holzman, Matthew J. Lazzara

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Kidney Glomerulus, Kidney, urologic and male genital diseases, Biochemistry, GST, glutathione S-transferase, Podocyte, Mice, HGF, PS, protamine sulfate, Phosphorylation, Receptor, MET, mesenchymal epithelial transition, biology, Hepatocyte Growth Factor, Podocytes, Chemistry, female genital diseases and pregnancy complications, Cell biology, phosphorylation–dephosphorylation, Intercellular Junctions, medicine.anatomical_structure, SHP-2, SH2 domain–containing protein tyrosine phosphatase-2, SHP-2, Slit diaphragm, Hepatocyte growth factor, Research Article, Glomerular Filtration Rate, Protein Binding, Signal Transduction, medicine.drug, Cell Line, FL, full length, Dephosphorylation, Nephrin, medicine, Animals, Humans, Molecular Biology, KD, knockdown, urogenital system, Membrane Proteins, Cell Biology, Actin cytoskeleton, ECD, extracellular domain, biology.protein, HGF, hepatocyte growth factor, Peptides, SNS, sticks-and-stones, CD, cytoplasmic domain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408b60f6059aaeab5052baf396505dd2
https://doi.org/10.1016/j.jbc.2021.101079

المؤلفون: Anne M. Gardner, Yow Yong Tan, Richard Fishel, Kristine E. Yoder, Nathan D. Jones, Ryan K. Messer, Gayan Senavirathne, Randi M. Kotlar, Anthony J. Rabe

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: bp, base pair, 0301 basic medicine, CIC, conserved intasome core, integration, Protomer, FRET, Förster resonance energy transfer, Biochemistry, Histones, chemistry.chemical_compound, Catalytic Domain, Nucleosome binding, biology, Chemistry, IN, integrase, Chromatin, Nucleosomes, Integrase, retrovirus, NPS, nucleosome positioning sequence, NED, amino terminal extension domain, prototype foamy virus, CCD, catalytic core domain, Research Article, Base pair, Virus Integration, TL, nucleosomes treated with trypsin to remove the histone tails, Genome, Viral, enzyme catalysis, Protein–protein interaction, FL, full length, Viral Proteins, 03 medical and health sciences, vDNA, viral DNA, Humans, Nucleosome, PFV, prototype foamy virus, ΔCTD, deletion of the CTD, Molecular Biology, PAGE, polyacrylamide gel electrophoresis, Integrases, 030102 biochemistry & molecular biology, ΔNTD, deletion of the NED and NTD, nucleosome, NTD, amino terminal domain, Cell Biology, CTD, carboxyl terminal domain, protein–protein interaction, 030104 developmental biology, DNA, Viral, biology.protein, Biophysics, Spumavirus, Protein Multimerization, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0972a0bff672c3b59ec64ad9561804f
https://doi.org/10.1016/j.jbc.2021.100550

المؤلفون: Li, Xiangming, Huang, Jing, Zhang, Min, Funakoshi, Ryota, Sheetij, Dutta, Spaccapelo, Roberta, Crisanti, Andrea, Nussenzweig, Victor, Nussenzweig, Ruth S., Tsuji, Moriya

المساهمون: Commission of the European Communities

المصدر: Vaccine

مصطلحات موضوعية: Immunology and Microbiology (all), Protozoan Proteins, EPITOPE, CD8-Positive T-Lymphocytes, Research & Experimental Medicine, Mice, FL, full-length, Mice, Inbred NOD, YOELII, Malaria, Falciparum, BERGHEI, SPOROZOITES, Human CD8+ T cell, Human immune system mice, Malaria, Protection, Recombinant adenovirus, Molecular Medicine, Veterinary (all), Public Health, Environmental and Occupational Health, Infectious Diseases, PLASMODIUM-FALCIPARUM, Ad, adenovirus, 11 Medical And Health Sciences, Dependovirus, IMMUNIZATION, FALCIPARUM CIRCUMSPOROZOITE PROTEIN, Medicine, Research & Experimental, Life Sciences & Biomedicine, Human CD8+T cell, CSP, circumsporozoite protein, Genetic Vectors, Plasmodium falciparum, Immunology, Mice, Transgenic, Article, ADENOVIRUS, Virology, Immunology and Microbiology(all), HLA-A2 Antigen, Malaria Vaccines, parasitic diseases, Animals, Humans, Pf, Plasmodium falciparum, Science & Technology, Public Health, Environmental and Occupational Health, CYTOTOXIC T-LYMPHOCYTES, 06 Biological Sciences, veterinary(all), TCR, T-cell receptor, AAV9, adeno-associated virus serotype 9, HIS, human immune system, Py, Plasmodium yoelii, 07 Agricultural And Veterinary Sciences, CLONES

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::17be66dba13ffaa1b84d18d89e021403

المؤلفون: Misun, Park, Susan F, Steinberg

المصدر: JACC: Basic to Translational Science

مصطلحات موضوعية: oxidant stress, GFX, GF109203X, AKT, cardiomyocytes, AKT, protein kinase B, HF, heart failure, CREB, cyclic adenosine monophosphate binding response element protein, cAMP, cyclic adenosine monophosphate, PRECLINICAL RESEARCH, ROS, reactive oxygen species, FL, full-length, cardioprotection, PKC, protein kinase C, PTX, pertussis toxin, β1-adrenergic receptor, βAR, β-adrenergic receptor, GRK, G protein–coupled receptor kinase, PKA, protein kinase A, ERK, extracellular regulated kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a833e8a933ed258f0a9f4fcc096a3b9d
https://pubmed.ncbi.nlm.nih.gov/30175276

المؤلفون: Eduardo N. Chini, Carlos Escande, Claudia Cs S. Chini, Veronica Nin

المصدر: Biochemical Journal

مصطلحات موضوعية: HFD, high-fat diet, Small interfering RNA, viruses, Circadian clock, Regulator, HDAC, histone deacetylase, Biochemistry, RAR-related orphan receptor alpha, Mice, 0302 clinical medicine, FL, full-length, RNA, Small Interfering, Mice, Knockout, HA, haemagglutinin, 0303 health sciences, DMEM, Dulbecco's modified Eagle's medium, Rev-erbα, Protein Stability, ARNTL Transcription Factors, Deleted in Breast Cancer 1 (DBC1), Circadian Rhythm, Cell biology, CLOCK, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, 030220 oncology & carcinogenesis, Plasmids, Signal Transduction, Research Article, ER, oestrogen receptor, Biology, Protein degradation, Transfection, Cell Line, Alas1, δ-aminolaevulinic acid synthase 1, HEK, human embryonic kidney, 03 medical and health sciences, FBS, fetal bovine serum, GSK3β, glycogen synthase kinase 3β, Circadian Clocks, DBC1, Deleted in Breast Cancer 1, Animals, Humans, LZ, leucine zipper, RNA, Messenger, Circadian rhythm, Molecular Biology, Adaptor Proteins, Signal Transducing, 030304 developmental biology, KO, knockout, BMAL1, PGC-1α, peroxisome-proliferator-activated receptor γ co-activator 1α, Cell Biology, MEF, mouse embryonic fibroblast, WT, wild-type, Molecular biology, Protein Structure, Tertiary, circadian, Gene Expression Regulation, Nuclear receptor, siRNA, small interfering RNA, Nuclear Receptor Subfamily 1, Group D, Member 1, AR, androgen receptor, NCoR, nuclear receptor co-repressor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a608ac30f926e77de0d0ee2a8b77e28
https://doi.org/10.1042/bj20121085

المؤلفون: Wanjie Li, Jianli Sang, Kangdi Hu, Haitao Wang, Ada Hang-Heng Wong, Jiaxin Gao, Yue Wang

المصدر: Biochemical Journal

مصطلحات موضوعية: YF, yeast form, TBST, Tris-buffered saline containing 0.1% Tween 20, Eukaryotic DNA replication, Biochemistry, DNA polymerase delta, environment and public health, TGE, Tris-glycine-EDTA, λPPase, lambda phosphatase, FL, full-length, Replication Protein A, Candida albicans, Phosphoprotein Phosphatases, Hydroxyurea, co-IP, co-immunoprecipitation, Phosphorylation, DNA, Fungal, HF, hyphal form, CDK, cyclin-dependent kinase, GFP, green fluorescent protein, ATM, ataxia telangiectasia mutated, dsDNA, double-stranded DNA, CTD, C-terminal domain, DNA-Binding Proteins, UTR, untranslated region, AP, alkaline phosphatase, protein–DNA interaction, PI3K, phosphoinositide 3-kinase, Research Article, DNA Replication, GMM, glucose minimal medium, Genes, Fungal, Molecular Sequence Data, Biology, EMSA, electrophoretic mobility-shift assay, phosphatase, Fungal Proteins, RPA, replication protein A, Replication factor C, Control of chromosome duplication, SeqA protein domain, Stress, Physiological, DNA-PK, DNA-dependent protein kinase, Cdc, cell division cycle, ssDNA, single-stranded DNA, DSB, double-strand break, Amino Acid Sequence, NTD, N-terminal domain, Molecular Biology, Replication protein A, Base Sequence, Sequence Homology, Amino Acid, DNA replication, G1 Phase, Cell Biology, replication protein A (RPA), dephosphorylation, WT, wild-type, Protein Structure, Tertiary, enzymes and coenzymes (carbohydrates), DBD, DNA-binding domain, Multiprotein Complexes, Origin recognition complex, HU, hydroxyurea

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0c5b48e1d6106adc87236d60ae284d
https://pubmed.ncbi.nlm.nih.gov/23140133