المؤلفون: Chandrasekaran, Abinaya, Dittlau, Katarina Stoklund, Corsi, Giulia I., Haukedal, Henriette, Doncheva, Nadezhda T., Ramakrishna, Sarayu, Ambardar, Sheetal, Salcedo, Claudia, Schmidt, Sissel I., Zhang, Yu, Cirera, Susanna, Pihl, Maria, Schmid, Benjamin, Nielsen, Troels Tolstrup, Nielsen, Jørgen E., Kolko, Miriam, Kobolák, Julianna, Dinnyés, András, Hyttel, Poul, Palakodeti, Dasaradhi, Gorodkin, Jan, Muddashetty, Ravi S., Meyer, Morten, Aldana, Blanca I., Freude, Kristine K.

المصدر: Stem Cell Reports MultiPark: Multidisciplinary research focused on Parkinson´s disease StemTherapy: National Initiative on Stem Cells for Regenerative Therapy. :2736-2751

مصطلحات موضوعية: autophagy, CHMP2B, complement 3, cytokines, FTD3, hiPSC-derived astrocytes, mitochondria, NF-kB, reactive astrocytes, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Neurovetenskaper, Medical and Health Sciences, Basic Medicine, Neurosciences

URL الوصول: https://lup.lub.lu.se/record/c9dd9a7f-6064-4665-b227-6ce4db71a793
http://dx.doi.org/10.1016/j.stemcr.2021.09.013

المؤلفون: Blanca I. Aldana, Yu Zhang, Pia Jensen, Abinaya Chandrasekaran, Sofie K. Christensen, Troels T. Nielsen, Jørgen E. Nielsen, Poul Hyttel, Martin R. Larsen, Helle S. Waagepetersen, Kristine K. Freude

المصدر: Molecular Brain, Vol 13, Iss 1, Pp 1-17 (2020)

مصطلحات موضوعية: FTD3, CHMP2B, iPSC-derived neuron, Glucose metabolism, Glutamate, Glutamine, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13041-020-00658-6; https://doaj.org/toc/1756-6606

URL الوصول: https://doaj.org/article/a1d2b2ffd35b48f5a544b4a38f6140ad

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المؤلفون: Aldana, Blanca I., Zhang, Yu^{Aff2, Aff3}, Jensen, Pia, Chandrasekaran, Abinaya, Christensen, Sofie K., Nielsen, Troels T., Nielsen, Jørgen E., Hyttel, Poul, Larsen, Martin R., Waagepetersen, Helle S., Freude, Kristine K.^Aff2

المصدر: Molecular Brain. 13(1)

المؤلفون: Yu Zhang, Benjamin Schmid, Nanett K. Nikolaisen, Mikkel A. Rasmussen, Blanca I. Aldana, Mikkel Agger, Kirstine Calloe, Tina C. Stummann, Hjalte M. Larsen, Troels T. Nielsen, Jinrong Huang, Fengping Xu, Xin Liu, Lars Bolund, Morten Meyer, Lasse K. Bak, Helle S. Waagepetersen, Yonglun Luo, Jørgen E. Nielsen, Bjørn Holst, Christian Clausen, Poul Hyttel, Kristine K. Freude

المصدر: Stem Cell Reports, Vol 8, Iss 3, Pp 648-658 (2017)

مصطلحات موضوعية: frontotemporal dementia linked to chromosome 3 (FTD3), CHMP2B, iPSC-derived neuron, disease modeling, endosome, mitochondria, iron homeostasis, oxidative stress, neurodegeneration, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671117300279; https://doaj.org/toc/2213-6711

URL الوصول: https://doaj.org/article/ddcff1aabf094e94bc737b7fbb9ee240

المؤلفون: Henriette Haukedal, Jørgen E. Nielsen, Sarayu Ramakrishna, Abinaya Chandrasekaran, Yu Zhang, Troels Tolstrup Nielsen, Giulia I. Corsi, Nadezhda Tsankova Doncheva, Maria Pihl, Andras Dinnyes, Sissel Ida Schmidt, Poul Hyttel, Julianna Kobolák, Blanca I. Aldana, Susanna Cirera, Morten Meyer, Dasaradhi Palakodeti, Sheetal Ambardar, Kristine K. Freude, Ravi S. Muddashetty, Miriam Kolko, Benjamin Schmid, Jan Gorodkin, Katarina Stoklund Dittlau, Claudia Salcedo

المصدر: Stem Cell Reports
Chandrasekaran, A, Dittlau, K S, Corsi, G I, Haukedal, H, Doncheva, N T, Ramakrishna, S, Ambardar, S, Salcedo, C, Schmidt, S I, Zhang, Y, Cirera, S, Pihl, M, Schmid, B, Nielsen, T T, Nielsen, J E, Kolko, M, Kobolák, J, Dinnyés, A, Hyttel, P, Palakodeti, D, Gorodkin, J, Muddashetty, R S, Meyer, M, Aldana, B I & Freude, K K 2021, ' Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3 ', Stem Cell Reports, vol. 16, no. 11, pp. 2736-2751 . https://doi.org/10.1016/j.stemcr.2021.09.013

مصطلحات موضوعية: autophagy, Induced Pluripotent Stem Cells, hiPSC-derived astrocytes, Biology, Mitochondrion, Biochemistry, Article, Mice, reactive astrocytes, Genetics, medicine, Animals, Homeostasis, Humans, Genetic Predisposition to Disease, RNA-Seq, NF-kB, Cells, Cultured, chemistry.chemical_classification, Reactive oxygen species, Endosomal Sorting Complexes Required for Transport, Gene Expression Profiling, Neurodegeneration, Autophagy, Neurotoxicity, CHMP2B, Cell Differentiation, Cell Biology, Charged multivesicular body protein 2B, medicine.disease, cytokines, Cell biology, Mitochondria, medicine.anatomical_structure, chemistry, mitochondrial fusion, Astrocytes, Frontotemporal Dementia, FTD3, Mutation, Glycolysis, complement 3, Developmental Biology, Astrocyte, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10f2e11f51a32fc79eeaba96fcf02bc
https://pubmed.ncbi.nlm.nih.gov/34678206

المؤلفون: Helle S. Waagepetersen, Yu Zhang, Kristine K. Freude, Abinaya Chandrasekaran, Troels Tolstrup Nielsen, Martin R. Larsen, Pia Jensen, Poul Hyttel, Blanca I. Aldana, Sofie K. Christensen, Jørgen E. Nielsen

المصدر: Aldana, B I, Zhang, Y, Jensen, P, Chandrasekaran, A, Christensen, S K, Nielsen, T T, Nielsen, J E, Hyttel, P, Larsen, M R, Waagepetersen, H S & Freude, K K 2020, ' Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia ', Molecular Brain, vol. 13, no. 1, 125 . https://doi.org/10.1186/s13041-020-00658-6
Molecular Brain
Molecular Brain, Vol 13, Iss 1, Pp 1-17 (2020)

مصطلحات موضوعية: Proteomics, 0301 basic medicine, Glutamine, Citric Acid Cycle, Induced Pluripotent Stem Cells, GDH, Glutamic Acid, Mitochondrion, Biology, Models, Biological, lcsh:RC346-429, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, medicine, Homeostasis, Humans, iPSC-derived neuron, Amino Acids, Induced pluripotent stem cell, Molecular Biology, lcsh:Neurology. Diseases of the nervous system, Neurons, Glucose metabolism, Research, Neurodegeneration, Glutamate receptor, CHMP2B, PAG, medicine.disease, Mitochondria, Cell biology, GS, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Astrocytes, Frontotemporal Dementia, FTD3, Hypermetabolism, Neuron, GC-MS, Glutamate, Energy Metabolism, Glycolysis, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ee9d29b84b4066e9d4117c0b4ccead
https://findresearcher.sdu.dk:8443/ws/files/173603330/s13041_020_00658_6.pdf

المؤلفون: Zhang, Yu, Schmid, Benjamin, Qas Younan, Nanett Kvist, Rasmussen, Mikkel A., Garcia, Blanca Irene Aldana, Agger, Mikkel, Callø, Kirstine, Stummann, Tina C., Larsen, Hjalte M., Nielsen, Troels T., Huang, Jinrong, Xu, Fengping, Liu, Xin, Bolund, Lars, Meyer, Morten, Bak, Lasse Kristoffer, Waagepetersen, Helle S., Luo, Yonglun, Nielsen, Jørgen Erik, Consortium, The FReJA, Holst, Bjørn, Clausen, Christian, Hyttel, Poul, Freude, Kristine

المصدر: Zhang, Y, Schmid, B, Nikolaisen, N K, Rasmussen, M A, Aldana, B I, Agger, M, Calloe, K, Stummann, T C, Larsen, H M, Nielsen, T, Huang, J, Xu, F, Liu, X, Bolund, L, Meyer, M, Bak, L K, Waagepetersen, H S, Luo, Y, Nielsen, J E, FReJA Consortium, Holst, B, Clausen, C, Hyttel, P & Freude, K K 2017, ' Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B ', Stem Cell Reports, vol. 8, no. 3, pp. 648-658 . https://doi.org/10.1016/j.stemcr.2017.01.012
Stem Cell Reports, Vol 8, Iss 3, Pp 648-658 (2017)
Zhang, Y, Schmid, B, Nikolaisen, N K, Rasmussen, M A, Aldana, B I, Agger, M, Calloe, K, Stummann, T C, Larsen, H M, Nielsen, T T, Huang, J, Xu, F, Liu, X, Bolund, L, Meyer, M, Bak, L K, Waagepetersen, H S, Luo, Y, Nielsen, J E, Holst, B, Clausen, C, Hyttel, P, Freude, K K & FReJA Consortium 2017, ' Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B ', Stem Cell Reports, vol. 8, no. 3 . https://doi.org/10.1016/j.stemcr.2017.01.012
Stem Cell Reports
Zhang, Y, Schmid, B, Qas Younan, N K, Rasmussen, M A, Garcia, B I A, Agger, M, Callø, K, Stummann, T C, Larsen, H M, Nielsen, T T, Huang, J, Xu, F, Liu, X, Bolund, L, Meyer, M, Bak, L K, Waagepetersen, H S, Luo, Y, Nielsen, J E, Consortium, T FRA, Holst, B, Clausen, C, Hyttel, P & Freude, K 2017, ' Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B ', Stem Cell Reports, vol. 8, no. 3, pp. 648-658 . https://doi.org/10.1016/j.stemcr.2017.01.012

مصطلحات موضوعية: 0301 basic medicine, Mitochondrion, Biochemistry, 0302 clinical medicine, disease modeling, oxidative stress, Induced pluripotent stem cell, lcsh:QH301-705.5, Neurons, Genetics, lcsh:R5-920, Neurodegeneration, CHMP2B, neurodegeneration, Cell Differentiation, Cellular Reprogramming, 3. Good health, Cell biology, mitochondria, Frontotemporal Dementia, lcsh:Medicine (General), Frontotemporal dementia, Endosome, Iron, Induced Pluripotent Stem Cells, Endosomes, Biology, Article, ESCRT, 03 medical and health sciences, medicine, Journal Article, Humans, iPSC-derived neuron, endosome, Endosomal Sorting Complexes Required for Transport, Gene Expression Profiling, Cell Biology, Charged multivesicular body protein 2B, frontotemporal dementia linked to chromosome 3 (FTD3), Fibroblasts, medicine.disease, 030104 developmental biology, lcsh:Biology (General), Mutation, iron homeostasis, Transcriptome, Cristae formation, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3292446787ef84a48323aa36645e7aea