يعرض 1 - 10 نتائج من 181 نتيجة بحث عن '"FXR, farnesoid-X-receptor"', وقت الاستعلام: 2.61s تنقيح النتائج
  1. 1

    المصدر: Acta Pharmaceutica Sinica. B
    Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)

    مصطلحات موضوعية: MCOLN1, mucolipin 1, Review, OPTN, optineurin, UPR, unfolded protein response, LIMP1, lysosomal integral membrane protein-1, General Pharmacology, Toxicology and Pharmaceutics, BNIP3L, BCL2 interacting protein 3 like, STBD1, starch-binding domain-containing protein 1, PLIN3, perilipin 3, LIR, LC3 interacting region, PPARα, peroxisomal proliferator-activated receptor-alpha, mTORC1, mammalian target of rapamycin complex 1, Translation (biology), WIPI1, WD repeat domain phosphoinositide-interacting protein 1, TBK1, serine/threonine-protein kinase, Cell biology, GIM, GABARAP-interacting motif, CREB, cAMP response element binding protein, PP2A, protein phosphatase 2a, Liver metabolism, CLN3, lysosomal/endosomal transmembrane protein, LALP70, lysosomal apyrase-like protein of 70 kDa, LD, lipid droplet, RETREG1, reticulophagy regulator 1, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, RM1-950, ATL3, Atlastin GTPase 3, RTNL3, a long isoform of RTN3, LAMP2, lysosomal-associated membrane protein-2, FXR, farnesoid X receptor, Farnesoid X receptor, Cryptochrome 1, FFA, free fatty acid, TFEB/TFE3, transcription factor EB, ULK1, Unc-51 like autophagy activating kinase 1, TRAC-1, thyroid-hormone-and retinoic acid-receptor associated co-repressor 1, RTN3, reticulon 3, S6K, P70-S6 kinase, SEC62, SEC62 homolog, preprotein translocation factor, GABARAPL1, GABA type A receptor associated protein like 1, TEX264, testis expressed 264, ER-phagy receptor, DFCP1, double FYVE-containing protein 1, LXRa, liver X receptor a, SLC36A1, solute carrier family 36 member 1, V-ATPase, vacuolar-ATPase, Regeneration (biology), Quality control, AIM, Atf8 interacting motif, VLDL, very-low-density lipoprotein, CYP7A1, cholesterol 7α-hydroxylase, NBR1, BRCA1 gene 1 protein, BCL2L13, BCL2 like 13, TGR5, takeda G protein receptor 5, NCoR1, nuclear receptor co-repressor 1, PKA, protein kinase A, Function (biology), CRY1, cryptochrome 1, LAMP1, lysosomal-associated membrane protein-1, Anabolism, S6RP, S6 ribosomal protein, LIMP3, lysosomal integral membrane protein-3, FAM134B, family with sequence similarity 134, member B, Nutrient regeneration, SPIN, spindling, FOXO1, Forkhead box O1, SCARB2, scavenger receptor class B member 2, PQLC2, PQ-loop protein, SQSTM1, sequestosome 1, CMA, chaperonin mediated autophagy, PLIN2, perilipin 2, PXR, pregnane X receptor, NPC-1, Niemann-Pick disease, type C1, SLC38A9, sodium-coupled neutral amino acid transporter 9, Lysosome, TRPML1, transient receptor potential mucolipin 1, BNIP3, BCL2 interacting protein 3, BA, bile acid, ATM, ATM serine/threonine kinase, CAR, constitutive androstane receptor, MFSD1, major facilitator superfamily domain containing 1, NAFLD, non-alcoholic fatty liver disease, PKB, protein kinase B, VDR, vitamin D3 receptor, SIRT1, sirtuin 1, LYAAT-1, lysosomal amino acid transporter 1, SNAT7, sodium-coupled neutral amino acid transporter 7, Biology, S1PR2, sphingosine-1-phosphate receptor 2, ROS, reactive oxygen species, CYP27A1, sterol 27-hydroxylase, Autophagy, NDP52, calcium-binding and coiled-coil domain-containing protein 2, ATGL, adipose triglyceride lipase, Signaling proteins, Catabolism, FUNDC1, FUN14 domain containing 1, CCPG1, cell cycle progression 1, LAAT-1, lysosomal amino acid transporter 1 homologue, PEX5, peroxisomal biogenesis factor 5, PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase, SLC38A7, solute carrier family 38 member 7, Therapeutics. Pharmacology, Homeostasis, Drug metabolism

  2. 2

    المصدر: Journal of Advanced Research

    مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, SREBPs, sterol regulatory element binding proteins, SREBP2, sterol regulatory element-binding protein 2, SHP, small heterodimer partner, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, LXRα, liver X receptor α, VLDL, very low-density lipoprotein, Multidisciplinary, TG, triglyceride, Bile acid, Chemistry, Fatty liver, FGF15/19, fibroblast growth factor 15/19, Cholesterol, WB, Western blot, ACC, Acetyl-CoA carboxylase, 030220 oncology & carcinogenesis, Lipogenesis, Quercetin, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, Bile acid metabolism, SDS, sodium dodecyl sulfate, TGR5, Takeda G-protein-coupled receptor 5, medicine.drug_class, Hyperoside, LC-MS, the combination of high-performance liquid chromatography and mass spectrometry, Article, Bile Acids and Salts, pACC, phosphorylated ACC, 03 medical and health sciences, Label-free proteomics, FXR, farnesoid X receptor, CYP27A1, sterol 27-hydroxylase, NAFLD, Internal medicine, medicine, Animals, Cholesterol metabolism, Liver X receptor, ComputingMethodologies_COMPUTERGRAPHICS, BAs, bile acids, SREBP1, sterol regulatory element-binding protein 1, Targeted metabolomics, Lipid Metabolism, CYP7A1, cholesterol 7α-hydroxylase, medicine.disease, Rats, TC, total cholesterol, QC, quality control, AMPK, AMP-activated protein kinase, 030104 developmental biology, Endocrinology, PMSF, phenylmethylsulfonyl fluoride, Apo, apolipoprotein, BSH, bile salt hydrolase, Farnesoid X receptor

  3. 3

    المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3847-3856 (2021)
    Acta Pharmaceutica Sinica. B

  4. 4

    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
    Cellular and Molecular Gastroenterology and Hepatology

    مصطلحات موضوعية: 0301 basic medicine, Gut Dysbiosis, OST-β, organic solute transporter subunit-β, SQSTM1, sequestosome-1, FGF15, CK19, cytokeratin 19, Gut flora, FEX, fexaramine, SHP, small heterodimer partner, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, AST, aspartate transaminase, MCA, muricholic acid, CYP8B1, cytochrome p450 family 8b1, BLU, Blu-9931, TCDCA, taurochenodeoxycholic acid, Original Research, FGFR4, fibroblast growth factor receptor 4, TBA, total bile acid, Liver injury, CA, cholic acid, biology, Bile acid, Gastroenterology, qRT-PCR, quantitative real-time polymerase chain reaction, Liver, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, NRF2, nuclear factor erythroid 2-related factor 2, BA, bile acid, 030211 gastroenterology & hepatology, TDCA, taurodeoxycholic acid, medicine.drug, medicine.medical_specialty, GM, gut microbiota, ALT, alanine transaminase, medicine.drug_class, TCA, taurocholic acid, PBS, phosphate-buffered saline, IBABP, ileal bile acid-binding protein, OST-α, organic solute transporter subunit-α, Liver Injury, ASBT (SLC10A2), apical sodium–bile acid transporter, CDCA, chenodeoxycholic acid, Bile Acids and Salts, CYP7A1, cytochrome p450 7a1, 03 medical and health sciences, FXR, farnesoid X receptor, ATG, autophagy-related gene, TUDCA, tauroursodeoxycholic acid, Internal medicine, medicine, Autophagy, BAS, bile acid sequestrants, lcsh:RC799-869, Cholestyramine, ALP, alkaline phosphatase, FGF15, fibroblast growth factor 15, SE, standard error, Hepatology, Fibroblast growth factor receptor 4, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, 030104 developmental biology, Endocrinology, DCA, deoxycholic acid, PCoA, principal coordinates analysis, BSH, bile salt hydrolase, ABX, antibiotics, TLCA, taurolithocholic acid, TMCA, tauromuricholic acid, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, NAFLD, nonalcoholic fatty liver disease

  5. 5

    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1519-1539 (2021)
    Cellular and Molecular Gastroenterology and Hepatology

    مصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, Peroxisome Proliferator-Activated Receptors, Nuclear Receptors, Receptors, Cytoplasmic and Nuclear, Review, AST, aspartate aminotransferase, RC799-869, FLINT, FXR ligand obeticholic acid for noncirrhotic, nonalcoholic steatohepatitis trial, SHP, small heterodimer partner, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, CCl4, carbon tetrachloride, MUFA, monounsaturated fatty acid, PNPLA3, polymorphisms in patatin-like phospholipase 3, Receptor, NOS, nitric oxide synthase, Liver X Receptors, Peroxisome Proliferator Activated Receptors (PPARs), CA, cholic acid, TNF, tumor necrosis factor, Bile acid, Nonalcoholic Steatohepatitis (NASH), Gastroenterology, SREBP1c, sterol regulatory element-binding protein 1c, WAT, white adipose tissue, NR, nuclear receptor, Diseases of the digestive system. Gastroenterology, Lipids, HSC, hepatic stellate cell, REGENERATE, Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment, OCA, obeticholic acid, NAFL, nonalcoholic fatty liver, BA, bile acid, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, NASH, nonalcoholic steatohepatitis, Metabolic Networks and Pathways, TLR, Toll-like receptor, ATP, adenosine triphosphate, Oxysterol, medicine.drug_class, HDL, high-density lipoprotein, Biology, CYP7A1, cytochrome P450 7A1, Farnesoid X Receptor (FXR), digestive system, APO-E2, apolipoprotein-E2, CDCA, chenodeoxycholic acid, 03 medical and health sciences, FXR, farnesoid X receptor, ALT, alanine aminotransferase, Liver X Receptor (LXR), medicine, Animals, Humans, Liver X receptor, SCD1, stearoyl-CoA desaturase 1, PPAR, peroxisome proliferator activated receptor, Hepatology, MCDD, methionine- and choline-deficient diet, medicine.disease, digestive system diseases, FGF, fibroblast growth factor, VLDLR, very-low-density lipoprotein receptor, 030104 developmental biology, CoA, Coenzyme A, Nuclear receptor, Gene Expression Regulation, Cancer research, Farnesoid X receptor, NAFLD, nonalcoholic fatty liver disease, Steatohepatitis, LXR, liver X receptor

  6. 6

    المساهمون: UCL - SSS/LDRI - Louvain Drug Research Institute, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de gastro-entérologie

    المصدر: JHEP reports, vol. 4, no. 1, pp. 100387
    JHEP Reports, Vol 4, Iss 1, Pp 100387-(2022)
    JHEP reports, Vol. 4, no.1, p. 100387 [1-13] (2022)
    JHEP Reports

    مصطلحات موضوعية: HFD, high-fat diet, CYP7A1, CYP8B1, sterol 12α-hydroxylase, WDF, western and high-fructose diet, FABP6, OGTT, oral glucose tolerance test, FGF15, RC799-869, ASBT, apical sodium-dependent BA transporter, chemistry.chemical_compound, OST, organic solute transporter, βMCA, β-muricholic acid, SHP, small heterodimer protein, WDF, CYP27A1, SHP, TNFα, Immunology and Allergy, LCA, lithocholic acid, DCA, FABP6, fatty acid binding protein 6, FGFR4, fibroblast growth factor receptor 4, CA, cholic acid, NAS, NAFLD activity score, CA, CYP7B1, CYP7B1, oxysterol 7α-hydroxylase, Bile acid, WT, αMCA, ND, normal diet, TGR5, Takeda G-protein coupled receptor 5, Chemistry, LCA, Deoxycholic acid, TLCA, TGR5, Gastroenterology, NASH, GLP-1, glucagon-like peptide-1, Diseases of the digestive system. Gastroenterology, G protein-coupled bile acid receptor, TNFα, tumor necrosis factor α, FXR, BA, bile acid, LPS, lipopolysaccharide, Research Article, CYP2A12, bile acid 7α-hydroxylase, ωMCA, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, ωMCA, ω-muricholic acid, LPS, normal diet, Normal diet, βMCA, medicine.drug_class, NASH, non-alcoholic steatohepatitis, education, tumor necrosis factor α, BA, digestive system, metabolic syndrome, CDCA, chenodeoxycholic acid, CYP2A12, CYP27A1, sterol 27-hydroxylase, Internal medicine, NAFLD, Internal Medicine, medicine, OGTT, CYP7A1, cholesterol 7α-hydroxylase, DCA, deoxycholic acid, FGF15, fibroblast growth factor 15, FXR, Farnesoid X receptor, TLCA, tauro-lithocholic acid, WT, wild-type, αMCA, α-muricholic acid, wild-type, CYP8B1, Hepatology, OST, medicine.disease, Endocrinology, NAS, FGFR4, CDCA, HFD, ND, Steatohepatitis, GLP-1, ASBT

    وصف الملف: application/pdf

  7. 7

    المساهمون: Lifestyle Medicine (LM), Center for Liver, Digestive and Metabolic Diseases (CLDM), Gastroenterology & Hepatology

    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 1, Pp 47-60 (2020)
    Cellular and molecular gastroenterology and hepatology, 9(1), 47-60. HANLEY & BELFUS-ELSEVIER INC
    Cellular and Molecular Gastroenterology and Hepatology
    Cellular and Molecular Gastroenterology and Hepatology, 9(1), 47-60. Elsevier Inc.

    وصف الملف: application/pdf

  8. 8

    المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 19-32 (2020)
    Acta Pharmaceutica Sinica. B

  9. 9

    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 149-170 (2020)
    Cellular and Molecular Gastroenterology and Hepatology

    مصطلحات موضوعية: 0301 basic medicine, Malabsorption, OATP, organic anion transporting polypeptide, Physiology-Based Modeling, Gallstones, uBA, unconjugated bile acid, Bile Acids, 0302 clinical medicine, Small intestinal bacterial overgrowth, Enterohepatic Circulation, FGF-19, fibroblast growth factor-19, Bile, Intestinal Mucosa, Enterohepatic circulation, tDCA, taurine-conjugated deoxycholic acid, Farnesoid X Receptor, Original Research, CA, cholic acid, Gastrointestinal tract, Cholesterol 7α-Hydroxylase, Bile acid, Chemistry, Liver Diseases, EHC, enterohepatic circulation, Gastroenterology, Gallbladder, gDCA, glycine-conjugated deoxycholic acid, uCA, unconjugated cholic acid, Editorial, Liver, BA, bile acid, CDCA, сhenodeoxycholic acid, 030211 gastroenterology & hepatology, uCDCA, unconjugated сhenodeoxycholic acid, Diarrhea, uDCA, unconjugated deoxycholic acid, medicine.medical_specialty, Biochemical Phenomena, medicine.drug_class, NTCP, sodium-taurocholate cotransporting polypeptide, Models, Biological, Permeability, Bile Acids and Salts, 03 medical and health sciences, FXR, farnesoid X receptor, Metabolic Diseases, Ileum, Internal medicine, gCA, glycine-conjugated cholic acid, tCDCA, taurine-conjugated сhenodeoxycholic acid, medicine, Humans, Fibroblast Growth Factor-19, lcsh:RC799-869, tCA, taurine-conjugated cholic acid, Hepatology, gCDCA, glycine-conjugated сhenodeoxycholic acid, Metabolism, CYP7A1, cholesterol 7α-hydroxylase, Lipid Metabolism, medicine.disease, ODE, ordinary differential equation, 030104 developmental biology, Endocrinology, DCA, deoxycholic acid, Intestinal Absorption, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, ASBT, apical sodium-dependent bile acid transporter, Gastrointestinal Motility, Flux (metabolism)

  10. 10

    المساهمون: Tytgat Institute for Liver and Intestinal Research, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Laboratory Genetic Metabolic Diseases, Experimental Vascular Medicine, ACS - Diabetes & metabolism, Laboratory for Endocrinology, Graduate School

    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 451-466 (2020)
    Cellular and Molecular Gastroenterology and Hepatology
    Cellular and molecular gastroenterology and hepatology, 10(3), 451-466. Elsevier Inc.