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المؤلفون: Jana Flegel, Saad Shaaban, Zhi Jun Jia, Britta Schulte, Yilong Lian, Adrian Krzyzanowski, Malte Metz, Tabea Schneidewind, Fabian Wesseler, Anke Flegel, Alisa Reich, Alexandra Brause, Gang Xue, Minghao Zhang, Lara Dötsch, Isabelle D. Stender, Jan-Erik Hoffmann, Rebecca Scheel, Petra Janning, Fraydoon Rastinejad, Dennis Schade, Carsten Strohmann, Andrey P. Antonchick, Sonja Sievers, Pedro Moura-Alves, Slava Ziegler, Herbert Waldmann
المصدر: Journal of Medicinal Chemistry. 65:16268-16289
مصطلحات موضوعية: Osteoblasts, Receptors, Aryl Hydrocarbon, Drug Discovery, Molecular Medicine, Hedgehog Proteins, Cell Differentiation, Signal Transduction
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المؤلفون: Fabian, Wesseler, Stefan, Lohmann, Daniel, Riege, Jonas, Halver, Aileen, Roth, Christian, Pichlo, Sabrina, Weber, Masanari, Takamiya, Eva, Müller, Jana, Ketzel, Jana, Flegel, Adrian, Gihring, Sepand, Rastegar, Jessica, Bertrand, Ulrich, Baumann, Uwe, Knippschild, Christian, Peifer, Sonja, Sievers, Herbert, Waldmann, Dennis, Schade
المصدر: Journal of medicinal chemistry. 65(22)
مصطلحات موضوعية: Osteogenesis, Bone Morphogenetic Proteins, Quinazolines, Bone Morphogenetic Protein 2, Cell Differentiation, Smad Proteins, Triazoles
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المؤلفون: Fabian Wesseler, Daniel Riege, Mahesh Puthanveedu, Jonas Halver, Eva Müller, Jessica Bertrand, Andrey P. Antonchick, Sonja Sievers, Herbert Waldmann, Dennis Schade
المصدر: Journal of medicinal chemistry. 65(5)
مصطلحات موضوعية: Transforming Growth Factor beta, Drug Discovery, Bone Morphogenetic Proteins, Molecular Medicine, Bone Morphogenetic Protein 2, Embryonic Development, High-Throughput Screening Assays, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Fabian Wesseler, Stefan Lohmann, Daniel Riege, Jonas Halver, Aileen Roth, Christian Pichlo, Sabrina Weber, Masanari Takamiya, Eva Müller, Jana Ketzel, Jana Flegel, Adrian Gihring, Sepand Rastegar, Jessica Bertrand, Ulrich Baumann, Uwe Knippschild, Christian Peifer, Sonja Sievers, Herbert Waldmann, Dennis Schade
المصدر: Journal of Medicinal Chemistry, 65 (22), 15263–15281
مصطلحات موضوعية: Life sciences, biology, ddc:570, Drug Discovery, Molecular Medicine
وصف الملف: application/pdf
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المؤلفون: Elena Reckzeh, Dennis Schade, Marc N. Hirt, Polla Magnus, Tessa Werner, Fabian Wesseler, Thomas Eschenhagen, Daniel Längle, Lauren Drowley, Niklas Schaumann, Alleyn T. Plowright
المصدر: ChemMedChem. 14:810-822
مصطلحات موضوعية: Dihydropyridines, Cardiac progenitors, Cardiac fibrosis, Induced Pluripotent Stem Cells, Myocardial Infarction, Smad Proteins, DHPS, Pharmacology, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Transforming Growth Factor beta, Drug Discovery, medicine, Animals, Humans, Myocytes, Cardiac, General Pharmacology, Toxicology and Pharmaceutics, Tissue Engineering, Tissue Scaffolds, 010405 organic chemistry, Chemistry, Organic Chemistry, Dihydropyridine, Dual mode, Cell Differentiation, Hit to lead, medicine.disease, Phenotype, Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Solubility, Drug Design, Molecular Medicine, Receptors, Transforming Growth Factor beta, medicine.drug, Transforming growth factor
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المؤلفون: Eva Rebecca Barth, Christopher Golz, Carsten Strohmann, Daniel Längle, Fabian Wesseler, Anna Krupp, Dennis Schade
مصطلحات موضوعية: Silicon, Germanium, chemistry.chemical_element, SMAD, Bioisosters, Combinatorial chemistry, Inorganic Chemistry, 1,4-Dihydropyridines, chemistry, Carbon, TGF inhibitors
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247c8714c869a6004522573d45136cac
http://hdl.handle.net/2003/39031 -
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المؤلفون: Fabian Wesseler, Uwe Knippschild, Dennis Schade, Balbina García-Reyes, Bernd Rathmer, Elena Brunstein, Christian Pichlo, Doris Henne-Bruns, Björn Jansen, Tanja Gehring, Ebru Karasu, Lydia Witt, Ulrich Baumann, Christian Peifer, Johann Leban
المصدر: Journal of medicinal chemistry. 61(9)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Casein Kinase 1 epsilon, Protein Conformation, Mutant, Binding, Competitive, 03 medical and health sciences, 0302 clinical medicine, Adenosine Triphosphate, Palmitoylation, Cell Line, Tumor, Drug Discovery, Transferase, Humans, Protein Kinase Inhibitors, Cell Proliferation, Kinase, Chemistry, Wnt signaling pathway, Ligand (biochemistry), PORCN, Wnt Proteins, 030104 developmental biology, Biochemistry, 030220 oncology & carcinogenesis, Casein Kinase Idelta, Drug Design, Molecular Medicine, Benzimidazoles, Casein kinase 1
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المؤلفون: Polla Magnus, Lauren Drowley, Alleyn T. Plowright, Daniel Längle, Marc N. Hirt, Dennis Schade, Niklas Schaumann, Elena Reckzeh, Fabian Wesseler, Tessa Werner, Thomas Eschenhagen
المصدر: ChemMedChem. 14:796-796
مصطلحات موضوعية: Pharmacology, Class (set theory), Chemistry, Stereochemistry, Organic Chemistry, Dihydropyridine, Hit to lead, Biochemistry, Front cover, Drug Discovery, medicine, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, medicine.drug