المؤلفون: Tredup, C, Ndreshkjana, B, Schneider, NS, Tjaden, A, Kemas, AM, Youhanna, S, Lauschke, VM, Berger, BT, Kramer, A, Berger, LM, Rohm, S, Knapp, S, Farin, HF, Muller, S

المصدر: ACS chemical biology. 18(4):822-836

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:152286777

المؤلفون: Menche C; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany., Schuhwerk H; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany., Armstark I; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany., Gupta P; Core Unit for Bioinformatics, Data Integration and Analysis, Center for Medical Information and Communication Technology, University Hospital Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany., Fuchs K; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany., van Roey R; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany., Mosa MH; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany., Hartebrodt A; Biomedical Network Science Lab, Department Artificial Intelligence in Biomedical Engineering (AIBE), FAU Erlangen-Nürnberg, Erlangen, Germany., Hajjaj Y; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany., Clavel Ezquerra A; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany., Selvaraju MK; Core Unit for Bioinformatics, Data Integration and Analysis, Center for Medical Information and Communication Technology, University Hospital Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany., Geppert CI; Institute of Pathology, University Hospital Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany., Bärthel S; Division of Translational Cancer Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Chair of Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technische Universität München, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany., Saur D; Division of Translational Cancer Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Chair of Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technische Universität München, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany.; Department of Internal Medicine II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Greten FR; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; German Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, Germany., Brabletz S; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany., Blumenthal DB; Biomedical Network Science Lab, Department Artificial Intelligence in Biomedical Engineering (AIBE), FAU Erlangen-Nürnberg, Erlangen, Germany., Weigert A; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, Germany.; Institute of Biochemistry I, Goethe University, Frankfurt am Main, Germany., Brabletz T; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany. thomas.brabletz@fau.de., Farin HF; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany. h.farin@georg-speyer-haus.de.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany. h.farin@georg-speyer-haus.de.; German Research Center (DKFZ), Heidelberg, Germany. h.farin@georg-speyer-haus.de.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, Germany. h.farin@georg-speyer-haus.de., Stemmler MP; Department of Experimental Medicine 1, Nikolaus-Fiebiger Center for Molecular Medicine, FAU Erlangen-Nürnberg, Erlangen, Germany. marc.stemmler@fau.de.

المصدر: EMBO reports [EMBO Rep] 2024 Aug; Vol. 25 (8), pp. 3406-3431. Date of Electronic Publication: 2024 Jun 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Blackwell Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

مواضيع طبية MeSH: Zinc Finger E-box-Binding Homeobox 1*/metabolism , Zinc Finger E-box-Binding Homeobox 1*/genetics , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/therapy , Colorectal Neoplasms*/immunology , Cancer-Associated Fibroblasts*/metabolism , Cancer-Associated Fibroblasts*/pathology , Inflammation*/metabolism , Inflammation*/genetics , Inflammation*/pathology , Immunotherapy*/methods, Animals ; Mice ; Humans ; Gene Expression Regulation, Neoplastic ; Fibroblasts/metabolism ; Cell Line, Tumor ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Epithelial-Mesenchymal Transition/genetics

المؤلفون: Kurmasheva N; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Said A; Department of Biochemistry Microbiology and Immunology, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, K1H 8L1, Canada., Wong B; Department of Biochemistry Microbiology and Immunology, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.; Ottawa Hospital Research Insitute, Ottawa, ON, K1H 8L6, Canada., Kinderman P; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., Han X; Lady Davis Institute, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC, H3T 1E2, Canada., Rahimic AHF; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Kress A; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; Faculty of Biological Sciences, Goethe University, 60438, Frankfurt am Main, Germany., Carter-Timofte ME; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Holm E; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., van der Horst D; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Kollmann CF; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Liu Z; Lady Davis Institute, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC, H3T 1E2, Canada., Wang C; Lady Davis Institute, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC, H3T 1E2, Canada., Hoang HD; Department of Biochemistry Microbiology and Immunology, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, K1H 8L1, Canada., Kovalenko E; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Chrysopoulou M; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Twayana KS; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Ottosen RN; Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark., Svenningsen EB; Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark., Begnini F; Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark., Kiib AE; Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark., Kromm FEH; Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark., Weiss HJ; School of Biochemistry and Immunology, Trinity College Dublin, Trinity Biomedical Sciences Institute, Dublin 2, Ireland., Di Carlo D; Pasteur Laboratories, Istituto Pasteur Italia - Fondazione Cenci Bolognetti, Rome, 00161, Italy., Muscolini M; Pasteur Laboratories, Istituto Pasteur Italia - Fondazione Cenci Bolognetti, Rome, 00161, Italy., Higgins M; Jacqui Wood Cancer Centre, Division of Cellular Medicine, School of Medicine, University of Dundee, Dundee, UK., van der Heijden M; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., Bardoul A; Cancer Axis, CHUM Research Centre, Montreal, Canada.; Department of Microbiology, Infectious Diseases and Immunology, Faculty of Medicine, University of Montreal, Montreal, Canada.; Institut du Cancer de Montréal, Montreal, QC, Canada., Tong T; Department of Neurosurgery, Aarhus University Hospital, 8200, Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, 8200, Aarhus N, Denmark.; DCCC Brain Tumor Center, Copenhagen University Hospital, Copenhagen, Denmark., Ozsvar A; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark.; Department of Clinical Medicine, Aarhus University, 8200, Aarhus N, Denmark., Hou WH; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Schack VR; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Holm CK; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark., Zheng Y; Small Molecule Therapeutics & Platform Technologies, AbbVie Inc., 1 North Waukegon Road, North Chicago, IL, 60064, USA., Ruzek M; AbbVie, Bioresearch Center, 100 Research Drive, Worcester, MA, 01608, USA., Kalucka J; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark.; Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark., de la Vega L; Jacqui Wood Cancer Centre, Division of Cellular Medicine, School of Medicine, University of Dundee, Dundee, UK., Elgaher WAM; Department of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University, E8.1, 66123, Saarbrücken, Germany., Korshoej AR; Department of Neurosurgery, Aarhus University Hospital, 8200, Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, 8200, Aarhus N, Denmark.; DCCC Brain Tumor Center, Copenhagen University Hospital, Copenhagen, Denmark., Lin R; Lady Davis Institute, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC, H3T 1E2, Canada., Hiscott J; Pasteur Laboratories, Istituto Pasteur Italia - Fondazione Cenci Bolognetti, Rome, 00161, Italy., Poulsen TB; Department of Chemistry, Aarhus University, 8000, Aarhus C, Denmark., O'Neill LA; School of Biochemistry and Immunology, Trinity College Dublin, Trinity Biomedical Sciences Institute, Dublin 2, Ireland., Roy DG; Cancer Axis, CHUM Research Centre, Montreal, Canada.; Department of Microbiology, Infectious Diseases and Immunology, Faculty of Medicine, University of Montreal, Montreal, Canada.; Institut du Cancer de Montréal, Montreal, QC, Canada., Rinschen MM; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark.; III. Department of Medicine and Hamburg Center for Kidney Health, Hamburg, Germany.; Aarhus Institute of Advanced Studies, Aarhus University, Aarhus, Denmark., van Montfoort N; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., Diallo JS; Department of Biochemistry Microbiology and Immunology, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.; Ottawa Hospital Research Insitute, Ottawa, ON, K1H 8L6, Canada., Farin HF; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site and German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Alain T; Department of Biochemistry Microbiology and Immunology, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, K1H 8L1, Canada., Olagnier D; Department of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark. olagnier@biomed.au.dk.

المصدر: Nature communications [Nat Commun] 2024 May 15; Vol. 15 (1), pp. 4096. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Oncolytic Virotherapy*/methods , Succinates*/pharmacology , Oncolytic Viruses*, Animals ; Humans ; Mice ; Cell Line, Tumor ; Interferon Type I/metabolism ; NF-E2-Related Factor 2/metabolism ; Colonic Neoplasms/therapy ; Colonic Neoplasms/immunology ; Colonic Neoplasms/drug therapy ; Antiviral Agents/pharmacology ; NF-kappa B/metabolism ; I-kappa B Kinase/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; Inflammation/drug therapy ; Female ; Vesicular stomatitis Indiana virus/physiology ; Vesicular stomatitis Indiana virus/drug effects ; Signal Transduction/drug effects

المؤلفون: Bidaud-Meynard A; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes)-UMR 6290, F-35000 Rennes, France. Electronic address: pbidaud@univ-rennes1.fr., Bourdais A; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes)-UMR 6290, F-35000 Rennes, France., Nicolle O; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes)-UMR 6290, F-35000 Rennes, France., Duclos M; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes)-UMR 6290, F-35000 Rennes, France., Saleh J; Université Paris Cité, CNRS, Institut Jacques Monod, F-75013 Paris, France., Ruemmele FM; Hôpital Necker Enfants Malades, Assistance publique - Hôpitaux de Paris, Université Paris Cité, Paris, France; INSERM, UMR1163, Imagine Institute, Paris, France., Farin HF; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany; German Cancer Consortium (Deutsches Konsortium für Translationale Krebsforschung), Heidelberg, Germany; German Cancer Research Center (Deutsches Krebsforschungszentrum), Heidelberg, Germany; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Delacour D; Aix-Marseille University, CNRS, IBDM (Developmental Biology Institute of Marseille)-UMR7288, F-13288 Marseille, France., Moshous D; Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France; INSERM, UMR1163, Imagine Institute, Paris, France., Michaux G; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes)-UMR 6290, F-35000 Rennes, France. Electronic address: gmichaux@univ-rennes1.fr.

المصدر: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2024; Vol. 17 (6), pp. 1072-1075. Date of Electronic Publication: 2024 Feb 16.

نوع المنشور: Letter; Journal Article

بيانات الدورية: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE

مواضيع طبية MeSH: Microvilli*/pathology , Microvilli*/metabolism , Atrophy*/pathology , Vacuolar Proton-Translocating ATPases*/metabolism , Vacuolar Proton-Translocating ATPases*/genetics, Animals ; Down-Regulation ; Humans ; Mice ; Intestines/pathology ; Intestinal Mucosa/pathology ; Intestinal Mucosa/metabolism

المؤلفون: Plattner C; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Lamberti G; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Blattmann P; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8092 Zurich, Switzerland., Kirchmair A; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Rieder D; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Loncova Z; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Sturm G; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Scheidl S; Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria., Ijsselsteijn M; Department of Pathology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Fotakis G; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Noureen A; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Lisandrelli R; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Böck N; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Nemati N; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Krogsdam A; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Daum S; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Finotello F; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria., Somarakis A; Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Schäfer A; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8092 Zurich, Switzerland., Wilflingseder D; Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, 6020 Innsbruck, Austria., Gonzalez Acera M; Department of Medicine 1, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054 Erlangen, Germany., Öfner D; Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, 6020 Innsbruck, Austria., Huber LA; Biocenter, Institute of Cell Biology, Medical University of Innsbruck, 6020 Innsbruck, Austria., Clevers H; Hubrecht Institute, 3584 CT Utrecht, the Netherlands., Becker C; Department of Medicine 1, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054 Erlangen, Germany., Farin HF; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, 60596 Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, a partnership with DKFZ Heidelberg, Frankfurt/Mainz, Germany., Greten FR; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, 60596 Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, a partnership with DKFZ Heidelberg, Frankfurt/Mainz, Germany., Aebersold R; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8092 Zurich, Switzerland., de Miranda NFCC; Department of Pathology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Trajanoski Z; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, 6020 Innsbruck, Austria.

المصدر: IScience [iScience] 2023 Nov 04; Vol. 26 (12), pp. 108399. Date of Electronic Publication: 2023 Nov 04 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

المؤلفون: Farin HF; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Mosa MH; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Ndreshkjana B; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Grebbin BM; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany., Ritter B; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Menche C; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Kennel KB; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Ziegler PK; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany., Szabó L; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany., Bollrath J; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany., Rieder D; Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria., Michels BE; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany., Kress A; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Bozlar M; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Darvishi T; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany., Stier S; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany., Kur IM; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; Institute of Biochemistry I, Goethe University, Frankfurt am Main, Germany., Bankov K; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany., Kesselring R; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of General and Visceral Surgery, University of Freiburg, Freiburg, Germany., Fichtner-Feigl S; Department of General and Visceral Surgery, University of Freiburg, Freiburg, Germany., Brüne B; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Biochemistry I, Goethe University, Frankfurt am Main, Germany., Goetze TO; Institute of Clinical Cancer Research IKF, Frankfurt am Main, Germany., Al-Batran SE; Institute of Clinical Cancer Research IKF, Frankfurt am Main, Germany., Brandts CH; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine, Goethe University, Frankfurt am Main, Germany., Bechstein WO; Department of General and Visceral Surgery, Goethe University, Frankfurt am Main, Germany., Wild PJ; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt am Main, Germany.; Frankfurt Institute for Advanced Studies (FIAS), Frankfurt am Main, Germany., Weigert A; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Biochemistry I, Goethe University, Frankfurt am Main, Germany., Müller S; Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt am Main, Germany.; Structural Genomics Consortium, Goethe University, Frankfurt am Main, Germany., Knapp S; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt am Main, Germany.; Structural Genomics Consortium, Goethe University, Frankfurt am Main, Germany., Trajanoski Z; Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria., Greten FR; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.

المصدر: Cancer discovery [Cancer Discov] 2023 Oct 05; Vol. 13 (10), pp. 2192-2211.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/metabolism , Cancer-Associated Fibroblasts*/metabolism, Humans ; Biological Specimen Banks ; Tumor Cells, Cultured ; Organoids/pathology ; Tumor Microenvironment/genetics

المؤلفون: Gajardo T; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France., Bernard M; UMR 144, Institut Curie, Paris, France; Institut Pierre-Gilles de Gennes, Paris Sciences and Letters Research University, Paris, France., Lô M; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France., Turck E; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France., Leveau C; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France., El-Daher MT; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France., Deslys A; Leukomotion Lab, Université de Paris Cité, CNRS, INSERM, Institut Necker-Enfants Malades, F-75015 Paris, France., Panikulam P; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France., Menche C; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt, Germany., Kurowska M; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France., Le Lay G; UMR 144, Institut Curie, Paris, France; Institut Pierre-Gilles de Gennes, Paris Sciences and Letters Research University, Paris, France., Barbier L; UMR 144, Institut Curie, Paris, France; Institut Pierre-Gilles de Gennes, Paris Sciences and Letters Research University, Paris, France., Moshous D; Imagine Institute, Université de Paris Cité, Paris, France; Pediatric Immunology Hematology and Rheumatology Department, Université Paris Cité, Paris, France., Neven B; Imagine Institute, Université de Paris Cité, Paris, France; Pediatric Immunology Hematology and Rheumatology Department, Université Paris Cité, Paris, France., Farin HF; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt, Germany., Fischer A; Imagine Institute, Université de Paris Cité, Paris, France; Pediatric Immunology Hematology and Rheumatology Department, Université Paris Cité, Paris, France; Collège de France, Paris, France., Ménasché G; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France., de Saint Basile G; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France; Centre d'Etude des Déficits Immunitaires, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France., Vargas P; UMR 144, Institut Curie, Paris, France; Institut Pierre-Gilles de Gennes, Paris Sciences and Letters Research University, Paris, France; Leukomotion Lab, Université de Paris Cité, CNRS, INSERM, Institut Necker-Enfants Malades, F-75015 Paris, France. Electronic address: pablo.vargas@inserm.fr., Sepulveda FE; Molecular Basis of Altered Immune Homeostasis Laboratory, Institut National de la Santé et de la Recherche Médicale (INSERM) Unite Mixte de Recherche (UMR) 1163, Paris, France; Imagine Institute, Université de Paris Cité, Paris, France; CNRS, Paris, France. Electronic address: fernando.sepulveda@inserm.fr.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2023 Oct; Vol. 152 (4), pp. 949-960. Date of Electronic Publication: 2023 Jun 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Actins* , Phosphatidylinositol 3-Kinases*, Humans ; Animals ; Mice ; Cell Death ; Mutation ; Cell Movement/genetics ; DNA Damage ; Proteins ; 1-Phosphatidylinositol 4-Kinase

المؤلفون: Ahmed A; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany.; Department of Pharmacology, Faculty of Medicine, University of Khartoum, Sudan., Reinhold C; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Breunig E; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Phan TS; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Dietrich L; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Kostadinova F; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Urwyler C; Department of Biology, Institute of Molecular Health Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland., Merk VM; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Noti M; Institute of Pathology, University of Bern, Switzerland., Toja da Silva I; International Research Center, A.C. Camargo Cancer Center, São Paulo, Brazil.; National Institute for Science and Technology - Oncogenomics and Therapeutic Innovation (INCT-INOTE), São Paulo, Brazil., Bode K; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Nahle F; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Plazzo AP; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany., Koerner J; Division of Immunology, Department of Biology, University of Konstanz, Germany., Stuber R; Institute of Pathology, University of Bern, Switzerland., Menche C; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Karamitopoulou E; Institute of Pathology, University of Bern, Switzerland., Farin HF; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany., Gollob KJ; International Research Center, A.C. Camargo Cancer Center, São Paulo, Brazil.; National Institute for Science and Technology - Oncogenomics and Therapeutic Innovation (INCT-INOTE), São Paulo, Brazil.; Albert Einstein Israelite Hospital, São Paulo, Brazil., Brunner T; Division of Biochemical Pharmacology, Department of Biology, University of Konstanz, Germany.

المصدر: Molecular oncology [Mol Oncol] 2023 Aug; Vol. 17 (8), pp. 1545-1566. Date of Electronic Publication: 2023 Mar 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Glucocorticoids*/pharmacology , Colorectal Neoplasms*/genetics, Humans ; Mice ; Animals ; Steroid 11-beta-Hydroxylase/metabolism ; Intestines ; Inflammation

المؤلفون: Vornholz L; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany., Isay SE; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany., Kurgyis Z; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany.; Department of Dermatology and Allergology, Technical University of Munich, Munich, Germany., Strobl DC; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany.; Institute of Computational Biology, Department of Computational Health, Helmholtz Center Munich, Neuherberg, Germany., Loll P; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany., Mosa MH; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt/Main, Germany.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany., Luecken MD; Institute of Computational Biology, Department of Computational Health, Helmholtz Center Munich, Neuherberg, Germany.; Institute of Lung Health and Immunity (LHI), Helmholtz Center Munich, Neuherberg, Germany.; Member of the German Center for Lung Research (DZL), Munich, Germany., Sterr M; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Lickert H; Institute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Stem Cell Research, Helmholtz Center Munich, Neuherberg, Germany.; School of Medicine, Technical University of Munich, Munich, Germany., Winter C; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), Munich partner site, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site, Germany., Greten FR; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt/Main, Germany.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Farin HF; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt/Main, Germany.; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Theis FJ; Institute of Computational Biology, Department of Computational Health, Helmholtz Center Munich, Neuherberg, Germany.; Department of Mathematics, Technical University of Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany., Ruland J; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), Munich partner site, Germany.; German Cancer Consortium (DKTK), Frankfurt/Mainz partner site, Germany.; German Center for Infection Research (DZIF), Munich partner site, Germany.

المصدر: Science advances [Sci Adv] 2023 Mar 17; Vol. 9 (11), pp. eadd8564. Date of Electronic Publication: 2023 Mar 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction* , Colonic Neoplasms*, Humans ; Animals ; Mice ; Antigen Presentation ; Antigen-Presenting Cells ; Genomic Instability ; Tumor Microenvironment

المؤلفون: Boonsanay V; Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt am Main, Germany., Mosa MH; Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt am Main, Germany., Looso M; Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Weichenhan D; Division of Cancer Epigenomics, German Cancer Research Center, Heidelberg, Germany., Ceteci F; Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt am Main, Germany., Pudelko L; Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany., Lechel A; Department of Internal Medicine I, Ulm University Hospital, Ulm, Germany., Michel CS; Department of Hematology, Medical Oncology, and Pneumology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Künne C; Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Farin HF; Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt am Main, Germany; German Cancer Consortium and German Cancer Research Center, Heidelberg, Germany., Plass C; Division of Cancer Epigenomics, German Cancer Research Center, Heidelberg, Germany; German Cancer Consortium and German Cancer Research Center, Heidelberg, Germany., Greten FR; Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt am Main, Germany; German Cancer Consortium and German Cancer Research Center, Heidelberg, Germany. Electronic address: greten@gsh.uni-frankfurt.de.

المصدر: Gastroenterology [Gastroenterology] 2023 Feb; Vol. 164 (2), pp. 214-227. Date of Electronic Publication: 2022 Nov 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE

مواضيع طبية MeSH: Colonic Neoplasms*/genetics , Histone-Lysine N-Methyltransferase*/metabolism, Animals ; Humans ; Mice ; Cell Transformation, Neoplastic/genetics ; Chromatin/genetics ; Colorectal Neoplasms/genetics ; Epigenesis, Genetic ; Histones/metabolism ; Heterografts