المؤلفون: Krüll J; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058, Erlangen, Germany., Fehler SK; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058, Erlangen, Germany., Hofmann L; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058, Erlangen, Germany., Nebel N; Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schwabachanlage 12, 91054, Erlangen, Germany., Maschauer S; Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schwabachanlage 12, 91054, Erlangen, Germany., Prante O; Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schwabachanlage 12, 91054, Erlangen, Germany., Gmeiner P; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058, Erlangen, Germany., Lanig H; Central Institute for Scientific Computing (ZISC), Friedrich-Alexander-Universität Erlangen-Nürnberg, Martensstr. 5a, 91058, Erlangen, Germany., Hübner H; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058, Erlangen, Germany., Heinrich MR; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058, Erlangen, Germany.

المصدر: ChemMedChem [ChemMedChem] 2020 Jul 03; Vol. 15 (13), pp. 1175-1186. Date of Electronic Publication: 2020 Jun 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

مواضيع طبية MeSH: Azo Compounds/*pharmacology , Buprenorphine/*pharmacology , Receptors, Opioid, mu/*agonists, Azo Compounds/chemical synthesis ; Azo Compounds/chemistry ; Buprenorphine/chemical synthesis ; Buprenorphine/chemistry ; Dose-Response Relationship, Drug ; Fluorine Radioisotopes ; HEK293 Cells ; Humans ; Ligands ; Molecular Structure ; Structure-Activity Relationship

المؤلفون: Nebel N; Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, Erlangen D-91054, Germany., Strauch B; Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, Erlangen D-91054, Germany., Maschauer S; Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, Erlangen D-91054, Germany., Lasch R; Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schuhstrasse 19, Erlangen D-91052, Germany., Rampp H; Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schuhstrasse 19, Erlangen D-91052, Germany., Fehler SK; Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schuhstrasse 19, Erlangen D-91052, Germany., Bock LR; Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schuhstrasse 19, Erlangen D-91052, Germany., Hübner H; Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schuhstrasse 19, Erlangen D-91052, Germany., Gmeiner P; Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schuhstrasse 19, Erlangen D-91052, Germany., Heinrich MR; Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schuhstrasse 19, Erlangen D-91052, Germany., Prante O; Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, Erlangen D-91054, Germany.

المصدر: ACS omega [ACS Omega] 2017 Dec 31; Vol. 2 (12), pp. 8649-8659. Date of Electronic Publication: 2017 Dec 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2470-1343 (Print) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE

المؤلفون: Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M

المصدر: Nature communications [Nat Commun] 2017 Apr 06; Vol. 8, pp. 15273. Date of Electronic Publication: 2017 Apr 06.

نوع المنشور: Journal Article; Published Erratum

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE

المؤلفون: Pegoraro S; 4SC AG, Am Klopferspitz 19a, 82152 Martinsried, Germany., Duffey M; Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, 69120 Heidelberg, Germany., Otto TD; Parasite Genomics, Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1SA, UK., Wang Y; Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, 69120 Heidelberg, Germany., Rösemann R; 4SC Discovery GmbH, Am Klopferspitz 19a, 82152 Martinsried, Germany., Baumgartner R; 4SC AG, Am Klopferspitz 19a, 82152 Martinsried, Germany., Fehler SK; 4SC AG, Am Klopferspitz 19a, 82152 Martinsried, Germany.; Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, 69120 Heidelberg, Germany., Lucantoni L; Eskitis Institute for Drug Discovery, Griffith University, Don Young, Nathan Queensland 4111, Australia., Avery VM; Eskitis Institute for Drug Discovery, Griffith University, Don Young, Nathan Queensland 4111, Australia., Moreno-Sabater A; Sorbonne Universités, UPMC Univ Paris 06, INSERM U1135, CNRS ERL 8255, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), 91 Bd de l'hôpital, F-75013 Paris, France.; AP-HP, Hôpital St Antoine, Service de Parasitologie-Mycologie, F-75012 Paris, France., Mazier D; Sorbonne Universités, UPMC Univ Paris 06, INSERM U1135, CNRS ERL 8255, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), 91 Bd de l'hôpital, F-75013 Paris, France.; AP-HP, Groupe hospitalier La Pitié-Salpêtrière, Service de Parasitologie-Mycologie, F-75013 Paris, France., Vial HJ; Dynamique des Interactions Membranaires Normales et Pathologiques, CNRS UMR 5235, Université Montpellier II, cc107, Place Eugène Bataillon, 34095 Montpellier, France., Strobl S; 4SC Discovery GmbH, Am Klopferspitz 19a, 82152 Martinsried, Germany., Sanchez CP; Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, 69120 Heidelberg, Germany., Lanzer M; Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.; German Center for Infection Research (DZIF), partner site Heidelberg, 69120 Heidelberg, Germany.

المصدر: Nature communications [Nat Commun] 2017 Jan 31; Vol. 8, pp. 14193. Date of Electronic Publication: 2017 Jan 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials/*pharmacology , Calcium-Transporting ATPases/*antagonists & inhibitors , Endoplasmic Reticulum/*drug effects , Malaria, Falciparum/*drug therapy , Plasmodium falciparum/*drug effects, Acute Disease ; Animals ; Antimalarials/chemical synthesis ; Antimalarials/pharmacokinetics ; Calcium-Transporting ATPases/genetics ; Calcium-Transporting ATPases/metabolism ; Disease Models, Animal ; Drug Resistance ; Endoplasmic Reticulum/metabolism ; Gene Expression ; Humans ; Inhibitory Concentration 50 ; Ion Transport ; Malaria, Falciparum/parasitology ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Plasmodium falciparum/genetics ; Plasmodium falciparum/growth & development ; Plasmodium falciparum/metabolism ; Structure-Activity Relationship

المؤلفون: Lasch R; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg , Schuhstraße 19, 91052 Erlangen, Germany., Fehler SK; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg , Schuhstraße 19, 91052 Erlangen, Germany., Heinrich MR; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg , Schuhstraße 19, 91052 Erlangen, Germany.

المصدر: Organic letters [Org Lett] 2016 Apr 01; Vol. 18 (7), pp. 1586-9. Date of Electronic Publication: 2016 Mar 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: PubMed not MEDLINE

المؤلفون: Nebel N, Maschauer S, Bartuschat AL, Fehler SK, Hübner H, Gmeiner P, Kuwert T, Heinrich MR, Prante O, Hocke C

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2014 Dec 01; Vol. 24 (23), pp. 5399-403.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Fluorine Radioisotopes*, Positron-Emission Tomography/*methods , Receptors, Dopamine D3/*chemistry, Humans ; Molecular Structure ; Radioligand Assay ; Structure-Activity Relationship

المؤلفون: Fehler SK; Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schuhstrasse 19, 91052 Erlangen (Germany) http://www.medchem.uni-erlangen.de/heinrichlab/, Pratsch G, Heinrich MR

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2014 Oct 13; Vol. 53 (42), pp. 11361-5. Date of Electronic Publication: 2014 Aug 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: PubMed not MEDLINE

المؤلفون: Cumming P; Department of Nuclear Medicine, Laboratory of Molecular Imaging and Radiochemistry, Friedrich Alexander University, Erlangen, Germany., Maschauer S; Department of Nuclear Medicine, Laboratory of Molecular Imaging and Radiochemistry, Friedrich Alexander University, Erlangen, Germany., Riss PJ; Department of Chemistry, Universitetet i Oslo & Norsk Medisinisk Syklotronsenter AS, Oslo, Norway., Tschammer N; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Emil Fischer Center, Friedrich Alexander University, Erlangen, Germany., Fehler SK; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Emil Fischer Center, Friedrich Alexander University, Erlangen, Germany., Heinrich MR; Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Emil Fischer Center, Friedrich Alexander University, Erlangen, Germany., Kuwert T; Department of Nuclear Medicine, Laboratory of Molecular Imaging and Radiochemistry, Friedrich Alexander University, Erlangen, Germany., Prante O; Department of Nuclear Medicine, Laboratory of Molecular Imaging and Radiochemistry, Friedrich Alexander University, Erlangen, Germany.

المصدر: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2014 Jul; Vol. 34 (7), pp. 1148-56. Date of Electronic Publication: 2014 Apr 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Validation Study

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE

مواضيع طبية MeSH: Brain/*diagnostic imaging , Dopamine Plasma Membrane Transport Proteins/*analysis , Fluorine Radioisotopes/*pharmacokinetics , Positron-Emission Tomography/*methods , Radiopharmaceuticals/*chemical synthesis, Animals ; Female ; Rats ; Rats, Sprague-Dawley

المؤلفون: Fehler SK; Abteilung für Chemie und Pharmazie, Pharmazeutische Chemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schuhstrasse 19, 91052 Erlangen (Germany)., Maschauer S, Höfling SB, Bartuschat AL, Tschammer N, Hübner H, Gmeiner P, Prante O, Heinrich MR

المصدر: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2014 Jan 07; Vol. 20 (2), pp. 370-5. Date of Electronic Publication: 2013 Dec 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

مواضيع طبية MeSH: Azo Compounds/*chemistry , Benzene Derivatives/*chemistry , Fluorides/*chemistry , Piperazines/*chemistry , Radiopharmaceuticals/*chemistry, Animals ; Azo Compounds/metabolism ; Benzene Derivatives/metabolism ; Brain/metabolism ; CHO Cells ; Cricetulus ; Esters ; Isotope Labeling ; Norepinephrine Plasma Membrane Transport Proteins/metabolism ; Organ Specificity ; Piperazines/metabolism ; Positron-Emission Tomography ; Radioligand Assay ; Radiopharmaceuticals/metabolism ; Rats ; Receptor, Serotonin, 5-HT1A/metabolism ; Receptors, Dopamine D3/metabolism