المؤلفون: Elvira-Blázquez D; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain., Fernández-Justel JM; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain., Arcas A; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain.; Clarivate, Barcelona, Spain., Statello L; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain., Goñi E; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain., González J; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain., Ricci B; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA., Zaccara S; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA., Raimondi I; New York Genome Center, New York, NY, USA. iraimondi@nygenome.org.; Weill Cornell Medicine, New York, NY, USA. iraimondi@nygenome.org., Huarte M; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain. maitehuarte@unav.es.; Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain. maitehuarte@unav.es.

المصدر: The EMBO journal [EMBO J] 2024 Aug; Vol. 43 (16), pp. 3494-3522. Date of Electronic Publication: 2024 Jul 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Blackwell Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Tumor Suppressor Protein p53*/metabolism , Tumor Suppressor Protein p53*/genetics, Humans ; RNA Splicing Factors/metabolism ; RNA Splicing Factors/genetics ; RNA-Binding Proteins/metabolism ; RNA-Binding Proteins/genetics ; Adenosine/metabolism ; Adenosine/analogs & derivatives ; Genomic Instability ; Cell Proliferation ; Gene Expression Regulation ; Nerve Tissue Proteins

المؤلفون: Hernández-Carralero E; Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain.; Escuela de Doctorado y Estudios de Posgrado, Universidad de la Laguna, Santa Cruz de Tenerife, Spain.; Instituto de Tecnologías Biomédicas, Centro de Investigaciones Biomédicas de Canarias, Facultad de Medicina, Campus Ciencias de la Salud, Universidad de La Laguna, Santa Cruz de Tenerife, Spain., Cabrera E; Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain., Rodríguez-Torres G; Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain.; Escuela de Doctorado y Estudios de Posgrado, Universidad de la Laguna, Santa Cruz de Tenerife, Spain.; Instituto de Tecnologías Biomédicas, Centro de Investigaciones Biomédicas de Canarias, Facultad de Medicina, Campus Ciencias de la Salud, Universidad de La Laguna, Santa Cruz de Tenerife, Spain., Hernández-Reyes Y; Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain.; Escuela de Doctorado y Estudios de Posgrado, Universidad de la Laguna, Santa Cruz de Tenerife, Spain.; Instituto de Tecnologías Biomédicas, Centro de Investigaciones Biomédicas de Canarias, Facultad de Medicina, Campus Ciencias de la Salud, Universidad de La Laguna, Santa Cruz de Tenerife, Spain., Singh AN; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK., Santa-María C; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Madrid, Spain., Fernández-Justel JM; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Madrid, Spain., Janssens RC; Department of Molecular Genetics, Oncode Institute, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Marteijn JA; Department of Molecular Genetics, Oncode Institute, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Evert BO; Department of Neurology, University Hospital Bonn, Bonn, Germany., Mailand N; Protein Signaling Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.; Center for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Gómez M; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Madrid, Spain., Ramadan K; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK., Smits VAJ; Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain.; Instituto de Tecnologías Biomédicas, Centro de Investigaciones Biomédicas de Canarias, Facultad de Medicina, Campus Ciencias de la Salud, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.; Universidad Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain., Freire R; Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain.; Instituto de Tecnologías Biomédicas, Centro de Investigaciones Biomédicas de Canarias, Facultad de Medicina, Campus Ciencias de la Salud, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.; Universidad Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain.

المصدر: Nucleic acids research [Nucleic Acids Res] 2023 Jun 23; Vol. 51 (11), pp. 5396-5413.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Ataxin-3*/genetics , Ataxin-3*/metabolism , Chromatin*/genetics , DNA Replication*, Humans ; DNA Damage ; Machado-Joseph Disease/genetics ; Repressor Proteins/metabolism

المؤلفون: Jodkowska K; DNA Replication Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.; Laboratory of Functional and Structural Genomics, Center of New Technologies, University of Warsaw, Warsaw, Poland.; Centre for Advanced Materials and Technologies, Warsaw University of Technology, Poleczki 19, 02-822 Warsaw, Poland., Pancaldi V; Computational Biology Life Sciences Group, Barcelona Supercomputing Center (BSC), Barcelona, Spain.; Université de Toulouse, Inserm, CNRS, Université Toulouse III-Paul Sabatier, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France., Rigau M; Computational Biology Life Sciences Group, Barcelona Supercomputing Center (BSC), Barcelona, Spain.; MRC London Institute of Medical Sciences, Du Cane Road, London W12 0NN, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK., Almeida R; Functional Organization of the Mammalian Genome Group, Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), Madrid, Spain., Fernández-Justel JM; Functional Organization of the Mammalian Genome Group, Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), Madrid, Spain., Graña-Castro O; Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.; Institute of Applied Molecular Medicine (IMMA-Nemesio Díez), San Pablo-CEU University, Boadilla del Monte, Madrid, Spain., Rodríguez-Acebes S; DNA Replication Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Rubio-Camarillo M; Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Carrillo-de Santa Pau E; Computational Biology Group, IMDEA Food Institute, Madrid, Spain., Pisano D; Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Al-Shahrour F; Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Valencia A; Computational Biology Life Sciences Group, Barcelona Supercomputing Center (BSC), Barcelona, Spain., Gómez M; Functional Organization of the Mammalian Genome Group, Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), Madrid, Spain., Méndez J; DNA Replication Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

المصدر: Nucleic acids research [Nucleic Acids Res] 2022 Nov 28; Vol. 50 (21), pp. 12149-12165.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Replication Origin*/genetics , Chromatin*/genetics, Animals ; Mice ; Mouse Embryonic Stem Cells/metabolism ; DNA Replication/genetics ; Cell Cycle Proteins/metabolism ; Mammals/genetics

المؤلفون: Gallego A; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Fernández-Justel JM; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Martín-Vírgala S; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Maslon MM; Center for Advanced Technology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 10, 61-614 Poznań, Poland.; Department of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Uniwersytetu Poznanskiego 6, 61-614 Poznań, Poland., Gómez M; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain.

المصدر: Genes [Genes (Basel)] 2022 Sep 14; Vol. 13 (9). Date of Electronic Publication: 2022 Sep 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

مواضيع طبية MeSH: Histones*/genetics , Histones*/metabolism , RNA Polymerase II*/genetics , RNA Polymerase II*/metabolism, Animals ; Chromatin/genetics ; Mice ; Promoter Regions, Genetic ; RNA, Messenger/genetics

المؤلفون: Fernández-Justel JM; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Santa-María C; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Martín-Vírgala S; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Ramesh S; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Ferrera-Lagoa A; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Salinas-Pena M; Instituto de Biología Molecular de Barcelona (IBMB-CSIC), Carrer de Baldiri Reixac, 15, 08028 Barcelona, Spain., Isoler-Alcaraz J; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Maslon MM; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Crewe South Road, Edinburgh EH4 2XU, UK., Jordan A; Instituto de Biología Molecular de Barcelona (IBMB-CSIC), Carrer de Baldiri Reixac, 15, 08028 Barcelona, Spain., Cáceres JF; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Crewe South Road, Edinburgh EH4 2XU, UK., Gómez M; Centro de Biología Molecular Severo Ochoa (CBMSO), Consejo Superior de Investigaciones Científicas/Universidad Autónoma de Madrid (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain. Electronic address: mgomez@cbm.csic.es.

المصدر: Cell reports [Cell Rep] 2022 Sep 13; Vol. 40 (11), pp. 111329.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin* , Histones*/metabolism, Methylation ; RNA, Untranslated/genetics ; RNA, Untranslated/metabolism ; Transcription Factors/metabolism

المؤلفون: Massip F; Université de Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Evolutive UMR 5558, Villleurbanne, France.; Berlin Institute for Medical Systems Biology, Max Delbrueck Center for Molecular Medicine, Berlin, Germany., Laurent M; Institut Jacques Monod, CNRS UMR7592, Université Paris Diderot, Equipe Labellisée Association pour la Recherche sur le Cancer, Paris, France., Brossas C; Institut Jacques Monod, CNRS UMR7592, Université Paris Diderot, Equipe Labellisée Association pour la Recherche sur le Cancer, Paris, France., Fernández-Justel JM; Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM). Nicolás Cabrera 1, 28049 Madrid, Spain., Gómez M; Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM). Nicolás Cabrera 1, 28049 Madrid, Spain., Prioleau MN; Institut Jacques Monod, CNRS UMR7592, Université Paris Diderot, Equipe Labellisée Association pour la Recherche sur le Cancer, Paris, France., Duret L; Université de Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Evolutive UMR 5558, Villleurbanne, France., Picard F; Université de Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Evolutive UMR 5558, Villleurbanne, France.

المصدر: Nucleic acids research [Nucleic Acids Res] 2019 Jun 04; Vol. 47 (10), pp. 5114-5125.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: CpG Islands* , DNA Replication* , Genome* , Replication Origin*, Animals ; Chickens ; G-Quadruplexes ; HeLa Cells ; Humans ; K562 Cells ; Mice ; Polymorphism, Genetic ; Polymorphism, Single Nucleotide ; Reproducibility of Results ; Species Specificity

المؤلفون: Almeida R; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM), Nicolás Cabrera 1, 28049, Madrid, Spain., Fernández-Justel JM; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM), Nicolás Cabrera 1, 28049, Madrid, Spain., Santa-María C; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM), Nicolás Cabrera 1, 28049, Madrid, Spain., Cadoret JC; Institut Jacques Monod, CNRS-Université Paris Diderot, 75205, Paris, France., Cano-Aroca L; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM), Nicolás Cabrera 1, 28049, Madrid, Spain., Lombraña R; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM), Nicolás Cabrera 1, 28049, Madrid, Spain., Herranz G; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM), Nicolás Cabrera 1, 28049, Madrid, Spain., Agresti A; San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milano, Italy., Gómez M; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa CBMSO (CSIC/UAM), Nicolás Cabrera 1, 28049, Madrid, Spain. mgomez@cbm.csic.es.

المصدر: Nature communications [Nat Commun] 2018 Apr 23; Vol. 9 (1), pp. 1590. Date of Electronic Publication: 2018 Apr 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Conformation*, Chromatin/*chemistry , DNA Replication/*physiology , Transcription, Genetic/*physiology, Animals ; Chromatin/physiology ; DNA Damage/physiology ; DNA Repair/physiology ; Fibroblasts ; Genomic Instability/physiology ; HCT116 Cells ; HMGB1 Protein/genetics ; HMGB1 Protein/metabolism ; Histones/genetics ; Histones/metabolism ; Humans ; Mice ; Mouse Embryonic Stem Cells ; Nucleosomes/metabolism ; Primary Cell Culture

المؤلفون: Lombraña R; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Álvarez A; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Fernández-Justel JM; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Almeida R; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Poza-Carrión C; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Gomes F; Centro Nacional de Biotecnología (CSIC), Darwin 3, 28049 Madrid, Spain., Calzada A; Centro Nacional de Biotecnología (CSIC), Darwin 3, 28049 Madrid, Spain., Requena JM; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain., Gómez M; Functional Organization of the Genome Group, Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Nicolás Cabrera 1, 28049 Madrid, Spain. Electronic address: mgomez@cbm.csic.es.

المصدر: Cell reports [Cell Rep] 2016 Aug 09; Vol. 16 (6), pp. 1774-1786. Date of Electronic Publication: 2016 Jul 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin/*parasitology , DNA/*metabolism , DNA Replication/*genetics , Leishmania major/*genetics, Animals ; DNA Replication Timing/genetics ; Eukaryotic Cells/parasitology ; Humans ; Nucleosomes/parasitology ; Parasites/genetics ; Replication Origin/genetics ; Transcription, Genetic