المؤلفون: Petrarolo, G, Quattrini, L, Gelardi, Elm, Ferraris, Dm, Colombo, G, Picarazzi, F, Mori, M, Nakano, I, Garavaglia, S, La Motta, C

مصطلحات موضوعية: cancer stem cells, aldehyde dehydrogenase inhibitors, Aldehyde dehydrogenase, cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3728::b3af3c566756a52ddbfadc4abd9c4da6
http://hdl.handle.net/11568/1067948

المؤلفون: Alberti M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, 28100 Novara, Italy., Poli G; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy., Broggini L; Institute of Molecular and Translational Cardiology, IRCCS Policlinico San Donato, Piazza Malan, 20097 San Donato Milanese, Italy., Sainas S; Department of Sciences and Drug Technology, University of Torino, Via P. Giuria 9, 10125 Torino, Italy., Rizzi M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, 28100 Novara, Italy., Boschi D; Department of Sciences and Drug Technology, University of Torino, Via P. Giuria 9, 10125 Torino, Italy., Ferraris DM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, 28100 Novara, Italy., Martino E; Department of Sciences and Drug Technology, University of Torino, Via P. Giuria 9, 10125 Torino, Italy., Ricagno S; Institute of Molecular and Translational Cardiology, IRCCS Policlinico San Donato, Piazza Malan, 20097 San Donato Milanese, Italy., Tuccinardi T; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy., Lolli ML; Department of Sciences and Drug Technology, University of Torino, Via P. Giuria 9, 10125 Torino, Italy., Miggiano R; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, 28100 Novara, Italy.

المصدر: Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2024 Jun 01; Vol. 80 (Pt 6), pp. 386-396. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101676043 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-7983 (Electronic) Linking ISSN: 20597983 NLM ISO Abbreviation: Acta Crystallogr D Struct Biol Subsets: MEDLINE

مواضيع طبية MeSH: Dihydroorotate Dehydrogenase* , Oxidoreductases Acting on CH-CH Group Donors*/chemistry , Oxidoreductases Acting on CH-CH Group Donors*/antagonists & inhibitors , Oxidoreductases Acting on CH-CH Group Donors*/metabolism, Humans ; Crystallography, X-Ray/methods ; Binding Sites ; Pyridines/chemistry ; Pyridines/pharmacology ; Protein Conformation ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Models, Molecular ; Protein Binding ; Hydrogen Bonding

المؤلفون: Alberti M; Department of Pharmaceutical Sciences, University of Eastern Piedmont, Novara, Italy., Sainas S; Department of Sciences and Drug Technology, University of Turin, Torino, Italy., Ronchi E; Department of Pharmaceutical Sciences, University of Eastern Piedmont, Novara, Italy., Lolli ML; Department of Sciences and Drug Technology, University of Turin, Torino, Italy., Boschi D; Department of Sciences and Drug Technology, University of Turin, Torino, Italy., Rizzi M; Department of Pharmaceutical Sciences, University of Eastern Piedmont, Novara, Italy., Ferraris DM; Department of Pharmaceutical Sciences, University of Eastern Piedmont, Novara, Italy., Miggiano R; Department of Pharmaceutical Sciences, University of Eastern Piedmont, Novara, Italy.

المصدر: FEBS letters [FEBS Lett] 2023 Aug; Vol. 597 (16), pp. 2119-2132. Date of Electronic Publication: 2023 Jun 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE

مواضيع طبية MeSH: Mycobacterium tuberculosis*/metabolism , Oxidoreductases Acting on CH-CH Group Donors*/chemistry , Oxidoreductases Acting on CH-CH Group Donors*/metabolism , Tuberculosis*, Humans ; Dihydroorotate Dehydrogenase ; Drug Delivery Systems ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/chemistry

المؤلفون: Sainas S; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Giorgis M; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Circosta P; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin 10043, Italy.; Molecular Biotechnology Center, University of Turin, Via Nizza 52, Turin 10126, Italy., Poli G; Department of Pharmacy, University of Pisa, Via Bonanno 6, Pisa 56126, Italy., Alberti M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, Novara 28100, Italy., Passoni A; Laboratory of Mass Spectrometry, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy., Gaidano V; Division of Hematology and Cell Therapy, AO Ordine Mauriziano, Largo Filippo Turati, 62, Turin 10128, Italy., Pippione AC; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Vitale N; Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, Turin 10126, Italy., Bonanni D; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy.; Life Science Department, University of Modena, Via Università 4, Modena 41121, Italy., Rolando B; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Cignetti A; Division of Hematology and Cell Therapy, AO Ordine Mauriziano, Largo Filippo Turati, 62, Turin 10128, Italy., Ramondetti C; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Lanno A; Laboratory of Mass Spectrometry, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy., Ferraris DM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, Novara 28100, Italy., Canepa B; GEM FORLAB, Via Ing. Comotto 36, Caluso, Turin, 10014, Italy., Buccinnà B; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Piccinini M; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Rizzi M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, Novara 28100, Italy., Saglio G; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin 10043, Italy.; Division of Hematology and Cell Therapy, AO Ordine Mauriziano, Largo Filippo Turati, 62, Turin 10128, Italy., Al-Karadaghi S; Department of Biochemistry and Structural Biology, Lund University, Naturvetarvägen 14, Box 124, Lund 221 00, Sweden., Boschi D; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Miggiano R; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, Novara 28100, Italy., Tuccinardi T; Molecular Biotechnology Center, University of Turin, Via Nizza 52, Turin 10126, Italy., Lolli ML; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy.

المصدر: Journal of medicinal chemistry [J Med Chem] 2022 Oct 13; Vol. 65 (19), pp. 12701-12724. Date of Electronic Publication: 2022 Sep 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/drug therapy , Oxidoreductases Acting on CH-CH Group Donors*, Animals ; Humans ; Mice ; Antiviral Agents/pharmacology ; Dihydroorotate Dehydrogenase ; Dipyridamole/therapeutic use ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Structure-Activity Relationship

المؤلفون: Gelardi ELM; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy., Caprioglio D; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy., Colombo G; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy., Del Grosso E; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy., Mazzoletti D; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy., Mattoteia D; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy., Salamone S; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy., Ferraris DM; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy.; IXTAL srl, Via Bovio 6, 28100, Novara, Italy., Aronica E; Department of (Neuro)Pathology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Stichting Epilepsie Instellingen Nederland (SEIN), Heemstede, The Netherlands., Nato G; Department of Life Sciences and System Biology, University of Turin, Via Accademia Albertina 13, Turin, Italy.; Neuroscience Institute Cavalieri Ottolenghi (NICO), 10043, Orbassano, TO, Italy., Buffo A; Department of Life Sciences and System Biology, University of Turin, Via Accademia Albertina 13, Turin, Italy.; Department of Neuroscience Rita Levi Montalcini, University of Turin, Via Cherasco 15, Turin, Italy., Rizzi M; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy., Magrassi L; Neurosurgery, Department of Clinical, Surgical, Diagnostic and Pediatric Science, University of Pavia, Foundation IRCCS Policlinico San Matteo, 27100, Pavia, Italy.; Istituto Di Genetica Molecolare IGM-CNR, Via Abbiategrasso 207, 27100, Pavia, Italy., Minassi A; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy. alberto.minassi@uniupo.it.; PlantaChem srls, Via Canobio 4/6, 28100, Novara, Italy. alberto.minassi@uniupo.it., Garavaglia S; Dipartimento di Scienze del Farmaco, University of Piemonte Orientale, Via Bovio, 6, 28100, Novara, Italy. silvia.garavaglia@uniupo.it.

المصدر: Communications biology [Commun Biol] 2022 Sep 01; Vol. 5 (1), pp. 895. Date of Electronic Publication: 2022 Sep 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

مواضيع طبية MeSH: Aldehyde Oxidoreductases*/chemistry , Aldehyde Oxidoreductases*/metabolism , Brain Neoplasms*/diagnosis , Brain Neoplasms*/metabolism , Brain Neoplasms*/surgery , Curcumin*/metabolism , Curcumin*/pharmacology , Glioblastoma*/diagnosis , Glioblastoma*/metabolism , Glioblastoma*/surgery, Aldehyde Dehydrogenase/chemistry ; Aldehyde Dehydrogenase/metabolism ; Early Diagnosis ; Fluorescent Dyes/metabolism ; Humans ; Neoplastic Stem Cells/metabolism

المؤلفون: Ferrario E; University of Piemonte Orientale, Department of Pharmaceutical Sciences, Largo Donegani 2, 28100 Novara, Italy., Miggiano R; University of Piemonte Orientale, Department of Pharmaceutical Sciences, Largo Donegani 2, 28100 Novara, Italy.; IXTAL srl, Via Bovio 6, 28100 Novara, Italy., Rizzi M; University of Piemonte Orientale, Department of Pharmaceutical Sciences, Largo Donegani 2, 28100 Novara, Italy., Ferraris DM; University of Piemonte Orientale, Department of Pharmaceutical Sciences, Largo Donegani 2, 28100 Novara, Italy.; IXTAL srl, Via Bovio 6, 28100 Novara, Italy.

المصدر: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2022 Jul 18; Vol. 20, pp. 3874-3883. Date of Electronic Publication: 2022 Jul 18 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology Country of Publication: Netherlands NLM ID: 101585369 Publication Model: eCollection Cited Medium: Print ISSN: 2001-0370 (Print) Linking ISSN: 20010370 NLM ISO Abbreviation: Comput Struct Biotechnol J Subsets: PubMed not MEDLINE

المؤلفون: Chacko S, Boshoff HIM, Singh V, Ferraris DM, Gollapalli DR, Zhang M, Lawson AP, Pepi MJ, Joachimiak A, Rizzi M, Mizrahi V, Cuny GD, Hedstrom L

المصدر: Journal of medicinal chemistry [J Med Chem] 2021 Dec 23; Vol. 64 (24), pp. 18233-18234. Date of Electronic Publication: 2021 Dec 02.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Desole C; Department of Oncology, University of Turin, Candiolo, Italy., Gallo S; Department of Oncology, University of Turin, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Vitacolonna A; Department of Oncology, University of Turin, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Vigna E; Department of Oncology, University of Turin, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Basilico C; Department of Oncology, University of Turin, Candiolo, Italy., Montarolo F; Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano, Italy.; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy., Zuppini F; Department of Oncology, University of Turin, Candiolo, Italy., Casanova E; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Miggiano R; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Novara, Italy.; IXTAL srl, Novara, Italy., Ferraris DM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Novara, Italy.; IXTAL srl, Novara, Italy., Bertolotto A; Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano, Italy., Comoglio PM; IFOM, FIRC Institute for Molecular Oncology, Milano, Italy., Crepaldi T; Department of Oncology, University of Turin, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.

المصدر: Frontiers in immunology [Front Immunol] 2021 Dec 03; Vol. 12, pp. 775151. Date of Electronic Publication: 2021 Dec 03 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Development*/methods , Protein Engineering*/methods , Recombinant Proteins*/genetics, Antibodies, Monoclonal/*pharmacology , Hepatocyte Growth Factor/*antagonists & inhibitors, Animals ; Antibodies, Monoclonal/genetics ; Antibodies, Monoclonal/therapeutic use ; Antibody Affinity ; Antineoplastic Agents, Immunological ; Cell Line ; Cloning, Molecular ; Encephalomyelitis, Autoimmune, Experimental/drug therapy ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Gene Expression ; Genetic Vectors/genetics ; Humans ; Mice ; Models, Molecular ; Mutagenesis ; Structure-Activity Relationship ; Treatment Outcome

المؤلفون: Gelardi ELM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, A. Avogadro, 28100 Novara, Italy., Colombo G; Department of Pharmaceutical Sciences, University of Piemonte Orientale, A. Avogadro, 28100 Novara, Italy., Picarazzi F; Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, 53100 Siena, Italy., Ferraris DM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, A. Avogadro, 28100 Novara, Italy., Mangione A; Department of Pharmaceutical Sciences, University of Piemonte Orientale, A. Avogadro, 28100 Novara, Italy., Petrarolo G; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy., Aronica E; Department of (Neuro)Pathology, Amsterdam UMC, University of Amsterdam, 1105 Amsterdam, The Netherlands.; Stichting Epilepsie Instellingen Nederland (SEIN), 2103 Heemstede, The Netherlands., Rizzi M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, A. Avogadro, 28100 Novara, Italy., Mori M; Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, 53100 Siena, Italy., La Motta C; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.; CISUP-Centre for Instrumentation Sharing, University of Pisa, 56126 Pisa, Italy., Garavaglia S; Department of Pharmaceutical Sciences, University of Piemonte Orientale, A. Avogadro, 28100 Novara, Italy.

المصدر: Cancers [Cancers (Basel)] 2021 Jan 19; Vol. 13 (2). Date of Electronic Publication: 2021 Jan 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Miggiano R; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy., Rizzi M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy., Ferraris DM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.

المصدر: Pathogens (Basel, Switzerland) [Pathogens] 2020 May 18; Vol. 9 (5). Date of Electronic Publication: 2020 May 18.

نوع المنشور: Editorial

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101596317 Publication Model: Electronic Cited Medium: Print ISSN: 2076-0817 (Print) Linking ISSN: 20760817 NLM ISO Abbreviation: Pathogens Subsets: PubMed not MEDLINE