نتائج البحث - "Filanesib"

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دورية أكاديمية

Kinesin spindle protein inhibitors in cancer: from high throughput screening to novel therapeutic strategies

المؤلفون: Rand Shahin, Salah Aljamal

المصدر: Future Science OA, Vol 8, Iss 3 (2022)

مصطلحات موضوعية: Eg5, filanesib, ispinesib, KIF11, kinesin spindle protein, KSP, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2056-5623

URL الوصول: https://doaj.org/article/52c2e2042021434cb609c37fa6014373

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دورية أكاديمية

KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics

المؤلفون: Milic, Bojan, Chakraborty, Anirban, Han, Kyuho, Bassik, Michael C., Block, Steven M.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2018 May . 115(20), E4613-E4622.

URL الوصول: https://www.jstor.org/stable/26509535

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دورية أكاديمية

First-in-human phase 1 study of filanesib (ARRY-520), a kinesin spindle protein inhibitor, in patients with advanced solid tumors

المؤلفون: LoRusso, Patricia M., Goncalves, Priscila H., Casetta, Lindsay, Carter, Judith A., Litwiler, Kevin, Roseberry, Dale, Rush, Selena, Schreiber, Jennifer, Simmons, Heidi M., Ptaszynski, Mieke, Sausville, Edward A.

المصدر: Investigational New Drugs: The Journal of New Anticancer Agents. April 2015 33(2):440-449

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Filanesib in combination with pomalidomide and dexamethasone in refractory MM patients: safety and efficacy, and association with alpha 1-acid glycoprotein (AAG) levels. Phase Ib/II Pomdefil clinical trial conducted by the Spanish MM group

المؤلفون: Javier de la Rubia, Ramón García-Sanz, Joan Bladé, Albert Oriol, Mª José Cejalvo, Aránzazu García-Mateo, Cristina Motlló, Mª Victoria Dourdil, Enrique M. Ocio, Joaquin Martinez-Lopez, Felipe de Arriba, Paula Rodriguez-Otero, Juan José Lahuerta, Jesús Martín-Sánchez, Maria-Victoria Mateos, Jesús F. San-Miguel, Mª Dolores García-Malo

المساهمون: Celgene

المصدر: British Journal of Haematology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Digital.CSIC. Repositorio Institucional del CSIC

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25b2cebc0a7f8ad37d769c3744eb09c
https://pubmed.ncbi.nlm.nih.gov/32501528

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KIF11 inhibitors filanesib and ispinesib inhibit meningioma growth in vitro and in vivo

المؤلفون: Amir Abdollahi, Gerhard Jungwirth, Andreas Unterberg, Tao Yu, Juergen Debus, Christel Herold-Mende, Montadar Alaa Eddine, Junguo Cao, Rolf Warta, Mahmoud Moustafa

المصدر: Cancer letters. 506

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b92a66f40add792479798508f239e7
https://pubmed.ncbi.nlm.nih.gov/33652084

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Filanesib in combination with pomalidomide and dexamethasone in refractory MM patients: safety and efficacy, and association with alpha 1-acid glycoprotein (AAG) levels. Phase Ib/II Pomdefil clinical trial conducted by the Spanish MM group

المؤلفون: Ocio EM, Motlló C, Rodríguez-Otero P, Martínez-López J, Cejalvo MJ, Martín-Sánchez J, Bladé J, García-Malo MD, Dourdil MV, García-Mateo A, de Arriba F, García-Sanz R, de la Rubia J, Oriol A, Lahuerta JJ, San-Miguel JF, Mateos MV

المصدر: BRITISH JOURNAL OF HAEMATOLOGY
r-FISABIO. Repositorio Institucional de Producción Científica
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r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

مصطلحات موضوعية: myeloma, filanesib, Pomalidomide, AAG, KSP

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1de18625dc6b8690f61f5aedb471ffe9
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7482

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Eg5 targeting agents: From new anti-mitotic based inhibitor discovery to cancer therapy and resistance

المؤلفون: Isabel Garcia-Saez, Dimitrios A. Skoufias

المساهمون: Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), ESRF (Grenoble)

المصدر: Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2021, 184, pp.114364. ⟨10.1016/j.bcp.2020.114364⟩
Biochemical Pharmacology, 2021, 184, pp.114364. ⟨10.1016/j.bcp.2020.114364⟩

مصطلحات موضوعية: 0301 basic medicine, Phases of clinical research, Kinesins, Antineoplastic Agents, [SDV.CAN]Life Sciences [q-bio]/Cancer, Antimitotic Agents, Biochemistry, Microtubules, Motor protein, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Adenosine Triphosphate, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Medicine, Animals, Humans, Molecular Targeted Therapy, Mitosis, Filanesib, Pharmacology, Kinesin motors, Biological Products, Clinical Trials as Topic, Binding Sites, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], business.industry, Drug discovery, Antimitotic drugs, Eg5, 3. Good health, Spindle apparatus, 030104 developmental biology, Monastrol, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Kinesin, business