المؤلفون: Nooruzzaman M; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA., Johnson KEE; Systems Genomics Section, NIH/NIAID/DIR/LPD, Bethesda, MD, USA., Rani R; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA., Finkelsztein EJ; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Caserta LC; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA., Kodiyanplakkal RP; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Wang W; Systems Genomics Section, NIH/NIAID/DIR/LPD, Bethesda, MD, USA., Hsu J; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Transplantation and Cellular Therapy Program, Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA., Salpietro MT; Institutional Biorepository Core, Weill Cornell Medicine, New York, NY, USA., Banakis S; Systems Genomics Section, NIH/NIAID/DIR/LPD, Bethesda, MD, USA., Albert J; Systems Genomics Section, NIH/NIAID/DIR/LPD, Bethesda, MD, USA., Westblade LF; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Zanettini C; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Marchionni L; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Soave R; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Ghedin E; Systems Genomics Section, NIH/NIAID/DIR/LPD, Bethesda, MD, USA. elodie.ghedin@nih.gov., Diel DG; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA. dgdiel@cornell.edu., Salvatore M; Department of Medicine, Weill Cornell Medicine, New York, NY, USA. mis2053@med.cornell.edu.; Department of Population Health Science, Weill Cornell Medicine, New York, NY, USA. mis2053@med.cornell.edu.

المصدر: Nature communications [Nat Commun] 2024 Sep 18; Vol. 15 (1), pp. 7999. Date of Electronic Publication: 2024 Sep 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/genetics , SARS-CoV-2*/drug effects , Alanine*/analogs & derivatives , Alanine*/therapeutic use , Alanine*/pharmacology , Adenosine Monophosphate*/analogs & derivatives , Adenosine Monophosphate*/therapeutic use , Adenosine Monophosphate*/pharmacology , Antiviral Agents*/therapeutic use , Antiviral Agents*/pharmacology , COVID-19*/virology , Immunocompromised Host* , Drug Resistance, Viral*/genetics , COVID-19 Drug Treatment* , Ritonavir*/therapeutic use , Ritonavir*/pharmacology , Mutation*, Animals ; Humans ; Female ; Male ; Middle Aged ; Aged ; Mesocricetus ; Adult ; Cricetinae ; Leucine ; Lactams ; Proline ; Nitriles ; Coronavirus RNA-Dependent RNA Polymerase

SCR Organism: SARS-CoV-2 variants

المؤلفون: Nooruzzaman M; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University., Johnson KEE; Systems Genomics Section, NIH/NIAID/DIR/LPD., Rani R; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University., Finkelsztein EJ; Department of Medicine, Weill Cornell Medicine., Caserta LC; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University., Kodiyanplakkal RP; Department of Medicine, Weill Cornell Medicine., Wang W; Systems Genomics Section, NIH/NIAID/DIR/LPD., Hsu J; Department of Medicine, Weill Cornell Medicine., Salpietro MT; Institutional Biorepository Core, Weill Cornell Medicine., Banakis S; Systems Genomics Section, NIH/NIAID/DIR/LPD., Albert J; Systems Genomics Section, NIH/NIAID/DIR/LPD., Westblade L; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine., Zanettini C; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine., Marchionni L; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine., Soave R; Department of Medicine, Weill Cornell Medicine., Ghedin E; Systems Genomics Section, NIH/NIAID/DIR/LPD., Diel DG; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University., Salvatore M; Department of Medicine, Weill Cornell Medicine.; Department of Population Health Science, Weill Cornell Medicine.

المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Jun 18. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

المؤلفون: Stevenson EM; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Terry S; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Copertino D; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Leyre L; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA., Danesh A; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Weiler J; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Ward AR; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Khadka P; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., McNeil E; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Bernard K; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Miller IG; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Ellsworth GB; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Johnston CD; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Finkelsztein EJ; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Zumbo P; Applied Bioinformatics Core, Weill Cornell Medical College, New York, NY, USA., Betel D; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Applied Bioinformatics Core, Weill Cornell Medical College, New York, NY, USA., Dündar F; Applied Bioinformatics Core, Weill Cornell Medical College, New York, NY, USA.; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA., Duncan MC; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada., Lapointe HR; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada., Speckmaier S; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada., Moran-Garcia N; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada., Papa MP; Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA., Nicholes S; Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA., Stover CJ; Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA., Lynch RM; Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA., Caskey M; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA., Gaebler C; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA., Chun TW; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases (NIAID, NIH, Bethesda, MD, USA., Bosque A; Dept of Microbiology Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA., Wilkin TJ; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Lee GQ; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Brumme ZL; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada., Jones RB; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. rbjones@med.cornell.edu.; Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA. rbjones@med.cornell.edu.

المصدر: Nature communications [Nat Commun] 2022 Aug 19; Vol. 13 (1), pp. 4888. Date of Electronic Publication: 2022 Aug 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/virology , COVID-19*/prevention & control , COVID-19 Vaccines*/immunology , HIV Infections*/immunology , HIV-1*, BNT162 Vaccine ; CD4-Positive T-Lymphocytes ; Granzymes ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/therapeutic use ; SARS-CoV-2 ; Vaccination ; Vaccines, Synthetic ; Virus Latency ; mRNA Vaccines ; nef Gene Products, Human Immunodeficiency Virus/genetics

المؤلفون: Schenck EJ; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York; and., Hoffman KL; Department of Population Health Sciences., Oromendia C; Department of Population Health Sciences., Sanchez E; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine., Finkelsztein EJ; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine., Hong KS; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; Department of Surgery and Critical Care Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea., Kabariti J; Information Technologies and Services, and., Torres LK; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York; and., Harrington JS; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York; and., Siempos II; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine., Choi AMK; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York; and., Campion TR Jr; Department of Population Health Sciences.; Information Technologies and Services, and.; Clinical and Translational Science Center, Weill Cornell Medicine, Cornell University, New York, New York.

المصدر: Annals of the American Thoracic Society [Ann Am Thorac Soc] 2021 Nov; Vol. 18 (11), pp. 1849-1860.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 101600811 Publication Model: Print Cited Medium: Internet ISSN: 2325-6621 (Electronic) Linking ISSN: 23256621 NLM ISO Abbreviation: Ann Am Thorac Soc Subsets: MEDLINE

مواضيع طبية MeSH: Organ Dysfunction Scores* , Oximetry*, Humans ; Intensive Care Units ; Oxygen ; Prognosis ; ROC Curve ; Retrospective Studies

المؤلفون: Yu AW; Department of Neurology, Yale University School of Medicine, New Haven, CT, USA., Finkelsztein EJ; Department of Internal Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, USA., Cheng NT; Department of Neurosciences, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, USA.

المصدر: The Neurohospitalist [Neurohospitalist] 2020 Jan; Vol. 10 (1), pp. 48-50. Date of Electronic Publication: 2019 Mar 06.

نوع المنشور: Case Reports

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101558199 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1941-8744 (Print) Linking ISSN: 19418744 NLM ISO Abbreviation: Neurohospitalist Subsets: PubMed not MEDLINE

المؤلفون: Pabón MA; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA.; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA., Patino E; Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA., Bhatia D; Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA., Rojas-Quintero J; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ma KC; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA., Finkelsztein EJ; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA., Osorio JC; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA.; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA., Malick F; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA., Polverino F; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Owen CA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ryter SW; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA., Choi AM; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA.; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA., Cloonan SM; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA., Choi ME; NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA.; Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA.

المصدر: JCI insight [JCI Insight] 2018 Sep 20; Vol. 3 (18). Date of Electronic Publication: 2018 Sep 20 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Acute Kidney Injury/*chemically induced , Acute Kidney Injury/*metabolism , Beclin-1/*metabolism , Pulmonary Disease, Chronic Obstructive/*complications , Smoke/*adverse effects , Nicotiana/*adverse effects, Acute Kidney Injury/pathology ; Animals ; Autophagy ; Beclin-1/genetics ; Cell Line ; Cell Survival ; Disease Models, Animal ; Epithelial Cells ; Female ; Fibrosis ; Gene Expression Profiling ; Humans ; Kidney/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria ; Oxidative Stress

المؤلفون: Ma KC; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; NewYork-Presbyterian Hospital., Schenck EJ; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; NewYork-Presbyterian Hospital., Siempos II; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine., Cloonan SM; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine., Finkelsztein EJ; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine., Pabon MA; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; Division of General Internal Medicine, Joan and Sanford I. Weill Department of Medicine, and., Oromendia C; Department of Healthcare Policy and Research, Division of Biostatistics and Epidemiology, Weill Cornell Medicine, New York, New York, USA., Ballman KV; Department of Healthcare Policy and Research, Division of Biostatistics and Epidemiology, Weill Cornell Medicine, New York, New York, USA., Baron RM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School. Boston, Massachusetts, USA., Fredenburgh LE; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School. Boston, Massachusetts, USA., Higuera A; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School. Boston, Massachusetts, USA., Lee JY; Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Chung CR; Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Jeon K; Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Yang JH; Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Howrylak JA; Division of Pulmonary, Allergy, and Critical Care Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA., Huh JW; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Suh GY; Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Choi AM; Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine.; NewYork-Presbyterian Hospital.

المصدر: JCI insight [JCI Insight] 2018 Jul 12; Vol. 3 (13). Date of Electronic Publication: 2018 Jul 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Critical Illness/*mortality , Multiple Organ Failure/*blood , Multiple Organ Failure/*mortality , Receptor-Interacting Protein Serine-Threonine Kinases/*blood , Receptor-Interacting Protein Serine-Threonine Kinases/*metabolism, Aged ; Apoptosis ; Female ; Hospital Mortality ; Humans ; Intensive Care Units ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Necrosis ; Odds Ratio ; Republic of Korea ; Severity of Illness Index ; Survival Analysis ; United States

المؤلفون: Sureshbabu A; Division of Pulmonary and Critical Care Medicine, and., Patino E; Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA., Ma KC; Division of Pulmonary and Critical Care Medicine, and., Laursen K; Department of Pharmacology., Finkelsztein EJ; Division of Pulmonary and Critical Care Medicine, and., Akchurin O; Department of Pediatrics, and., Muthukumar T; Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA.; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, New York, USA., Ryter SW; Division of Pulmonary and Critical Care Medicine, and., Gudas L; Department of Pharmacology., Choi AMK; Division of Pulmonary and Critical Care Medicine, and.; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, New York, USA., Choi ME; Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, New York, USA.; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, New York, USA.

المصدر: JCI insight [JCI Insight] 2018 Jun 07; Vol. 3 (11). Date of Electronic Publication: 2018 Jun 07 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Acute Kidney Injury/*pathology , Kidney Tubules/*pathology , Receptor-Interacting Protein Serine-Threonine Kinases/*metabolism , Shock, Septic/*complications, Acute Kidney Injury/blood ; Acute Kidney Injury/etiology ; Acute Kidney Injury/urine ; Adult ; Aged ; Aged, 80 and over ; Animals ; Apoptosis ; Biomarkers/blood ; Biomarkers/urine ; Cell Line ; Epithelial Cells/cytology ; Epithelial Cells/pathology ; Epithelial Cells/ultrastructure ; Female ; Humans ; Kidney Tubules/cytology ; Kidney Tubules/ultrastructure ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microscopy, Electron, Transmission ; Middle Aged ; Mitochondria/pathology ; Mitochondria/ultrastructure ; NADPH Oxidase 4/metabolism ; Necrosis/pathology ; Oxidative Stress ; Primary Cell Culture ; RNA, Small Interfering/metabolism ; Receptor-Interacting Protein Serine-Threonine Kinases/blood ; Receptor-Interacting Protein Serine-Threonine Kinases/genetics ; Receptor-Interacting Protein Serine-Threonine Kinases/urine ; Shock, Septic/blood ; Shock, Septic/urine ; Up-Regulation ; Young Adult

المؤلفون: Siempos II; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA.; First Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, University of Athens Medical School, Athens, Greece., Ma KC; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA., Imamura M; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA., Baron RM; Division of Pulmonary and Critical Medicine, Brigham and Women's Hospital (BWH), Harvard Medical School, Boston, Massachusetts, USA., Fredenburgh LE; Division of Pulmonary and Critical Medicine, Brigham and Women's Hospital (BWH), Harvard Medical School, Boston, Massachusetts, USA., Huh JW; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Moon JS; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA., Finkelsztein EJ; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA., Jones DS; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA., Lizardi MT; Department of Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, WCM, New York, New York, USA., Schenck EJ; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA., Ryter SW; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA., Nakahira K; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, Weill Cornell Medicine (WCM), New York, New York, USA., Choi AM; Department of Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, WCM, New York, New York, USA.

المصدر: JCI insight [JCI Insight] 2018 May 03; Vol. 3 (9). Date of Electronic Publication: 2018 May 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Protein Kinases/*blood , Protein Kinases/*deficiency , Receptor-Interacting Protein Serine-Threonine Kinases/*blood , Receptor-Interacting Protein Serine-Threonine Kinases/*deficiency , Respiration, Artificial/*adverse effects , Ventilator-Induced Lung Injury/*blood, Aged ; Animals ; Bronchoalveolar Lavage Fluid/chemistry ; Cell Death/genetics ; Cohort Studies ; Fatty Acids/metabolism ; Female ; Humans ; Intensive Care Units ; Male ; Mice ; Middle Aged ; Oxidation-Reduction ; Protein Kinases/genetics ; Protein Kinases/metabolism ; Receptor-Interacting Protein Serine-Threonine Kinases/genetics ; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism ; Ventilator-Induced Lung Injury/physiopathology

المؤلفون: Finkelsztein EJ; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Jones DS; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Ma KC; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Pabón MA; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Delgado T; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Nakahira K; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Arbo JE; Department of Medicine, Division of Emergency Medicine and Pulmonary Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Berlin DA; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Schenck EJ; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Choi AM; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA., Siempos II; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA. isiempos@yahoo.com.; First Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, University of Athens Medical School, Athens, Greece. isiempos@yahoo.com.; New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA. isiempos@yahoo.com.

المصدر: Critical care (London, England) [Crit Care] 2017 Mar 26; Vol. 21 (1), pp. 73. Date of Electronic Publication: 2017 Mar 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE

مواضيع طبية MeSH: Organ Dysfunction Scores* , Severity of Illness Index*, Sepsis/*diagnosis , Systemic Inflammatory Response Syndrome/*physiopathology, APACHE ; Aged ; Critical Illness/epidemiology ; Emergency Service, Hospital/organization & administration ; Emergency Service, Hospital/statistics & numerical data ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Patients' Rooms/organization & administration ; Patients' Rooms/statistics & numerical data ; Prognosis ; Registries/statistics & numerical data ; Risk Assessment/methods ; Risk Assessment/standards ; Sepsis/epidemiology ; Sepsis/physiopathology ; Systemic Inflammatory Response Syndrome/diagnosis ; Systemic Inflammatory Response Syndrome/epidemiology