المؤلفون: Nakamura, Jean, Mroue, R, Huang, B, Braunstein, S, Firestone, AJ, Nakamura, JL

URL الوصول: https://escholarship.org/uc/item/3sd761nw

المؤلفون: Nakamura, Jean, Mroue, R, Huang, B, Braunstein, S, Firestone, AJ, Nakamura, JL

URL الوصول: https://escholarship.org/uc/item/2k67s778

المؤلفون: Amy R. Howell, Kevin Shannon, Anthony D. Long, Predovic M, Bihua Huang, Remsberg, Inguva A, Micah J. Niphakis, Nhi Ngo, Radu M. Suciu, Stewart K. Richardson, Kenneth M. Lum, Hanigan Tw, Firestone Aj, Cassandra L. Henry, Benjamin F. Cravatt, Zambetti Na

مصطلحات موضوعية: chemistry.chemical_classification, Membrane, Enzyme, chemistry, Palmitoylation, Proteome, Lipase inhibitors, medicine, Myeloid leukemia, Cancer, Oncogenicity, medicine.disease, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ee779cfd11259dabc59a9be1a2d0354a
https://doi.org/10.1101/2020.05.21.108316

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المؤلفون: Randolph JT; Abbvie Inc., North Chicago, Illinois 60064, United States., O'Connor MJ; Abbvie Inc., North Chicago, Illinois 60064, United States., Han F; Abbvie Inc., North Chicago, Illinois 60064, United States., Hutchins CW; Abbvie Inc., North Chicago, Illinois 60064, United States., Siu YA; Abbvie Inc., North Chicago, Illinois 60064, United States., Cho M; Calico Life Sciences LLC, South San Francisco, California 94080, United States., Zheng Y; Abbvie Inc., North Chicago, Illinois 60064, United States., Hickson JA; Abbvie Inc., North Chicago, Illinois 60064, United States., Markley JL; Abbvie Inc., North Chicago, Illinois 60064, United States., Manaves V; Abbvie Inc., North Chicago, Illinois 60064, United States., Algire M; Abbvie Inc., North Chicago, Illinois 60064, United States., Baker KA; Abbvie Inc., North Chicago, Illinois 60064, United States., Chapman AM; Abbvie Inc., North Chicago, Illinois 60064, United States., Gopalakrishnan SM; Abbvie Inc., North Chicago, Illinois 60064, United States., Panchal SC; Abbvie Inc., North Chicago, Illinois 60064, United States., Foster-Duke K; Abbvie Inc., North Chicago, Illinois 60064, United States., Stolarik DF; Abbvie Inc., North Chicago, Illinois 60064, United States., Kempf-Grote A; Abbvie Inc., North Chicago, Illinois 60064, United States., Dammeier D; Abbvie Inc., North Chicago, Illinois 60064, United States., Fossey S; Abbvie Inc., North Chicago, Illinois 60064, United States., Sun Q; Abbvie Inc., North Chicago, Illinois 60064, United States., Sun C; Abbvie Inc., North Chicago, Illinois 60064, United States., Shen Y; Abbvie Inc., North Chicago, Illinois 60064, United States., Dart MJ; Abbvie Inc., North Chicago, Illinois 60064, United States., Kati WM; Abbvie Inc., North Chicago, Illinois 60064, United States., Lai A; Abbvie Inc., North Chicago, Illinois 60064, United States., Firestone AJ; Calico Life Sciences LLC, South San Francisco, California 94080, United States., Kort ME; Abbvie Inc., North Chicago, Illinois 60064, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2023 Mar 23; Vol. 66 (6), pp. 3852-3865. Date of Electronic Publication: 2023 Mar 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis* , Neoplasms*, Mice ; Animals ; Phospholipid Hydroperoxide Glutathione Peroxidase/metabolism ; Biological Availability

المؤلفون: Suciu RM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Luvaga IK; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Hazeen A; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Weerasooriya C; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Richardson SK; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Firestone AJ; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Shannon K; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Howell AR; Department of Chemistry, University of Connecticut, Storrs, CT, USA. Electronic address: amy.howell@uconn.edu., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. Electronic address: cravatt@scripps.edu.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Dec 01; Vol. 53, pp. 128414. Date of Electronic Publication: 2021 Oct 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Proteomics*, Lactones/*analysis , Propiolactone/*analogs & derivatives , Sulfones/*analysis , ras Proteins/*metabolism, Humans ; Lactones/metabolism ; Lactones/pharmacology ; Molecular Structure ; Propiolactone/analysis ; Propiolactone/metabolism ; Propiolactone/pharmacology ; Sulfones/metabolism ; Sulfones/pharmacology ; ras Proteins/antagonists & inhibitors ; ras Proteins/chemistry

المؤلفون: Remsberg JR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Suciu RM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Zambetti NA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Hanigan TW; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Firestone AJ; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Inguva A; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Long A; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Ngo N; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Lum KM; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Henry CL; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA., Richardson SK; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Predovic M; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA., Huang B; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Dix MM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Howell AR; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Niphakis MJ; Lundbeck La Jolla Research Center, Inc., San Diego, CA, USA. MIIP@lundbeck.com., Shannon K; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. Kevin.Shannon@ucsf.edu.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. Kevin.Shannon@ucsf.edu., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. cravatt@scripps.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2021 Aug; Vol. 17 (8), pp. 856-864. Date of Electronic Publication: 2021 Apr 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane/*metabolism , Hydrolases/*metabolism , Leukemia, Myeloid, Acute/*metabolism , Leukemia, Promyelocytic, Acute/*metabolism , ras Proteins/*metabolism, Cell Proliferation ; Cells, Cultured ; Humans ; Leukemia, Myeloid, Acute/pathology ; Leukemia, Promyelocytic, Acute/pathology ; Lipoylation ; Microsomes, Liver/chemistry ; Microsomes, Liver/metabolism ; Molecular Structure