المؤلفون: Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Snyder SC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Starczynowski DT; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO.

المصدر: Blood [Blood] 2024 Jun 06; Vol. 143 (23), pp. 2414-2424.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/pathology , Myeloproliferative Disorders*/metabolism , NF-kappa B*/metabolism , Signal Transduction*, Animals ; Mice ; Humans ; Mice, Knockout ; Interleukin-1 Receptor-Associated Kinases/metabolism ; Interleukin-1 Receptor-Associated Kinases/genetics ; Transcription Factor RelA/metabolism ; Transcription Factor RelA/genetics

المؤلفون: Collins TB; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Sturgeon CM; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai School of Medicine, New York, NY; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY., Batista LFZ; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; Center for Genome Integrity, Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO. Electronic address: stoh@wustl.edu.

المصدر: Experimental hematology [Exp Hematol] 2024 Apr; Vol. 132, pp. 104178. Date of Electronic Publication: 2024 Feb 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms* , Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/metabolism, Humans ; Erythropoiesis/genetics ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Signal Transduction ; Mutation ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Nuclear Proteins/genetics ; Protein-Arginine N-Methyltransferases/genetics ; Protein-Arginine N-Methyltransferases/metabolism

المؤلفون: Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Snyder SC; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Shim K; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO. Electronic address: stoh@wustl.edu.

المصدر: Experimental hematology [Exp Hematol] 2023 Dec; Vol. 128, pp. 48-66. Date of Electronic Publication: 2023 Aug 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Polycythemia Vera*/genetics , Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/metabolism, Mice ; Humans ; Animals ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Mutation ; Hematopoietic Stem Cells/metabolism ; Hematopoiesis/genetics ; Protein Serine-Threonine Kinases/genetics

المؤلفون: Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Yu L; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., He F; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Cox MJ; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

المصدر: American journal of hematology [Am J Hematol] 2023 Jul; Vol. 98 (7), pp. 1029-1042. Date of Electronic Publication: 2023 May 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Janus Kinase Inhibitors*/therapeutic use , Myeloproliferative Disorders*/genetics , Bone Marrow Neoplasms*, Humans ; Protein Kinase Inhibitors/therapeutic use ; Janus Kinase 2/genetics

المؤلفون: Lu P; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, USA.; Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, USA.; Program in Quantitative Molecular Therapeutics, Washington University School of Medicine, St. Louis, USA., Oetjen KA; Department of Medicine, Washington University School of Medicine, St. Louis, USA., Bender DE; The Bursky Center for Human Immunology and Immunotherapy Programs Immunomonitoring Laboratory, Washington University School of Medicine, St. Louis, USA., Ruzinova MB; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, USA., Fisher DAC; Department of Medicine, Washington University School of Medicine, St. Louis, USA., Shim KG; Department of Medicine, Washington University School of Medicine, St. Louis, USA., Pachynski RK; Department of Medicine, Washington University School of Medicine, St. Louis, USA., Brennen WN; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, USA.; Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, USA., Oh ST; Department of Medicine, Washington University School of Medicine, St. Louis, USA.; The Bursky Center for Human Immunology and Immunotherapy Programs Immunomonitoring Laboratory, Washington University School of Medicine, St. Louis, USA.; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, USA., Link DC; Department of Medicine, Washington University School of Medicine, St. Louis, USA.; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, USA., Thorek DLJ; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, USA. thorekd@wustl.edu.; Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, USA. thorekd@wustl.edu.; Program in Quantitative Molecular Therapeutics, Washington University School of Medicine, St. Louis, USA. thorekd@wustl.edu.; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, USA. thorekd@wustl.edu.; Oncologic Imaging Program, Siteman Cancer Center, Washington University School of Medicine, St. Louis, USA. thorekd@wustl.edu.

المصدر: Nature communications [Nat Commun] 2023 Mar 23; Vol. 14 (1), pp. 1601. Date of Electronic Publication: 2023 Mar 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Tomography, X-Ray Computed*/methods , Algorithms*, Humans ; Signal-To-Noise Ratio ; Artifacts ; Image Cytometry ; Image Processing, Computer-Assisted/methods

المؤلفون: Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Yang K; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Yu L; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Poittevin De La Frégonnière L; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Wang AZ; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA., Ruzinova MB; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Fowles JS; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Cox MJ; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Celik H; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Challen GA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Huang S; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. stoh@wustl.edu.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. stoh@wustl.edu.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA. stoh@wustl.edu.

المصدر: Nature cancer [Nat Cancer] 2023 Jan; Vol. 4 (1), pp. 108-127. Date of Electronic Publication: 2022 Dec 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Myeloproliferative Disorders*/drug therapy , Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/metabolism , Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/genetics, Animals ; Mice ; Humans ; Signal Transduction/genetics ; Janus Kinases/metabolism ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Dual Specificity Phosphatase 6/metabolism

المؤلفون: Paracatu LC; Department of Pediatrics, Division of Hematology/Oncology, Washington University School of Medicine, St. Louis, MO., Monlish DA; Department of Pediatrics, Division of Hematology/Oncology, Washington University School of Medicine, St. Louis, MO., Greenberg ZJ; Department of Pediatrics, Division of Hematology/Oncology, Washington University School of Medicine, St. Louis, MO., Fisher DAC; Department of Medicine, Division of Hematology, Washington University School of Medicine, St. Louis, MO., Walter MJ; Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO., Oh ST; Department of Medicine, Division of Hematology, Washington University School of Medicine, St. Louis, MO., Schuettpelz LG; Department of Pediatrics, Division of Hematology/Oncology, Washington University School of Medicine, St. Louis, MO. Electronic address: schuettpelz_l@wustl.edu.

المصدر: Experimental hematology [Exp Hematol] 2022 Jun; Vol. 110, pp. 47-59. Date of Electronic Publication: 2022 Apr 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Cytokines* , Myelodysplastic Syndromes*/metabolism, Bone Marrow/pathology ; Humans ; Toll-Like Receptor 1 ; Toll-Like Receptor 2/metabolism ; Toll-Like Receptor 6/metabolism ; Toll-Like Receptors/metabolism ; Transforming Growth Factor beta

المؤلفون: Zhou A; Washington University in St. Louis, St. Louis, Missouri, USA., Kong T; Washington University in St. Louis, St. Louis, Missouri, USA., Fowles JS; Washington University in St. Louis, St. Louis, Missouri, USA., Jung CL; University of California, California, Los Angeles, USA., Allen MJ; Washington University in St. Louis, St. Louis, Missouri, USA., Fisher DAC; Washington University in St. Louis, St. Louis, Missouri, USA., Fulbright M; Washington University in St. Louis, St. Louis, Missouri, USA., Nemeth E; University of California, California, Los Angeles, USA., Ganz T; University of California, California, Los Angeles, USA., Oh ST; Washington University in St. Louis, St. Louis, Missouri, USA.

المصدر: British journal of haematology [Br J Haematol] 2022 May; Vol. 197 (4), pp. e49-e52. Date of Electronic Publication: 2022 Feb 06.

نوع المنشور: Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE

مواضيع طبية MeSH: Primary Myelofibrosis*/drug therapy, Hepcidins ; Humans ; Nitriles ; Pyrazoles/therapeutic use ; Pyrimidines

المؤلفون: Kong T; Division of Hematology, Department of Medicine., Laranjeira ABA; Division of Hematology, Department of Medicine., Collins TB; Division of Hematology, Department of Medicine., De Togni ES; Division of Hematology, Department of Medicine., Wong AJ; Division of Hematology, Department of Medicine., Fulbright MC; Division of Hematology, Department of Medicine., Ruzinova M; Department of Pathology and Immunology, and., Celik H; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; and., Challen GA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; and., Fisher DAC; Division of Hematology, Department of Medicine., Oh ST; Division of Hematology, Department of Medicine.; Department of Pathology and Immunology, and.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO.

المصدر: Blood advances [Blood Adv] 2022 Jan 25; Vol. 6 (2), pp. 611-623.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/pathology , Myeloproliferative Disorders*/drug therapy , Myeloproliferative Disorders*/pathology , Primary Myelofibrosis*/pathology, Animals ; Cyclopentanes/therapeutic use ; Humans ; Mice ; Pyrimidines

المؤلفون: Celik H; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Krug E; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Zhang CR; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Han W; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Issa N; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Koh WK; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Bjeije H; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Kukhar O; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Allen M; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Li T; Center of Regenerative Medicine, Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri., Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Fowles JS; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Wong TN; Division of Hematology and Oncology, University of Michigan, Ann Arbor, Michigan., Stubbs MC; Incyte Research Institute, Wilmington, Delaware., Koblish HK; Incyte Research Institute, Wilmington, Delaware., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Challen GA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.

المصدر: Cancer discovery [Cancer Discov] 2021 Dec 01; Vol. 11 (12), pp. 3126-3141.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/pathology , Myeloproliferative Disorders*/complications , Myeloproliferative Disorders*/drug therapy , Myeloproliferative Disorders*/genetics, Animals ; Clonal Evolution/genetics ; Disease Models, Animal ; Humans ; Mice ; Mutation