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1دورية أكاديمية
المؤلفون: Maja L. Hansen, Malene Ambjørn, Mikkel N. Harndahl, Tau Benned-Jensen, Karina Fog, Kaare Bjerregaard-Andersen, Florence Sotty
المصدر: Cells, Vol 13, Iss 3, p 253 (2024)
مصطلحات موضوعية: alpha-synuclein, pre-formed fibrils, protein aggregation, neurofilament light chain, biomarkers, neurodegeneration, Cytology, QH573-671
وصف الملف: electronic resource
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2دورية أكاديميةEarly impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model
المؤلفون: Aleksandra Parka, Caroline Degel, Jakob Dreyer, Ulrike Richter, Benjamin Hall, Jesper F. Bastlund, Bettina Laursen, Maiken Nedergaard, Florence Sotty, Paolo Botta
المصدر: Neurobiology of Disease, Vol 178, Iss , Pp 106012- (2023)
مصطلحات موضوعية: Tauopathy, rTg4510, Alzheimer's disease, Frontotemporal dementia, Calcium imaging, Pyramidal neurons, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Ditte Olsen, Niels Wellner, Mathias Kaas, Inge E. M. de Jong, Florence Sotty, Michael Didriksen, Simon Glerup, Anders Nykjaer
المصدر: Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2158-3188
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4دورية أكاديمية
المؤلفون: Michael Aagaard Andersen, Kenneth Vielsted Christensen, Lassina Badolo, Garrick Paul Smith, Ross Jeggo, Poul Henning Jensen, Kathrine Just Andersen, Florence Sotty
المصدر: Neurobiology of Disease, Vol 116, Iss , Pp 13-27 (2018)
مصطلحات موضوعية: PFE-360, LRRK2 inhibition, LRRK2 inhibitor, Parkinson's disease, AAV-alpha-synuclein, In vivo electrophysiology, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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5دورية أكاديمية
المؤلفون: Nanna H. Jensen, Thomas I. Cremers, Florence Sotty
المصدر: The Scientific World Journal, Vol 10, Pp 1870-1885 (2010)
مصطلحات موضوعية: Technology, Medicine, Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1537-744X
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6Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model
المؤلفون: Aleksandra Parka, Caroline Degel, Jakob Dreyer, Ulrike Richter, Benjamin Hall, Jesper F. Bastlund, Bettina Laursen, Maiken Nedergaard, Florence Sotty, Paolo Botta
مصطلحات موضوعية: Neurology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf94423770a145bf7d12ad0689d9ea16
https://doi.org/10.1101/2022.10.13.512017 -
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المؤلفون: Aleksandra Parka, Christiane Volbracht, Benjamin Hall, Jesper F. Bastlund, Maiken Nedergaard, Bettina Laursen, Paolo Botta, Florence Sotty
مصطلحات موضوعية: Psychiatry and Mental health, Clinical Psychology, General Neuroscience, General Medicine, Geriatrics and Gerontology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca20943b3e2d95222ff90c9c55ba758e
https://doi.org/10.1101/2022.10.03.510063 -
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المؤلفون: Karsten Skjødt, Jan Egebjerg, Jan Torleif Pedersen, Fredrik Kartberg, Christiane Volbracht, Florence Sotty, Nina Helen Rosenqvist, Lars Østergaard Pedersen, Einar M. Sigurdsson, Ayodeji A. Asuni, Pia Jul, Christian Rungsted Andersson, Jeppe Falsig, Lone Helboe, Jeffrey B. Stavenhagen, Justus Claus Alfred Daechsel, Søren Christensen
المصدر: Alzheimer's & Dementia : Translational Research & Clinical Interventions
Rosenqvist, N, Asuni, A A, Andersson, C R, Christensen, S, Daechsel, J A, Egebjerg, J, Falsig, J, Helboe, L, Jul, P, Kartberg, F, Pedersen, L Ø, Sigurdsson, E M, Sotty, F, Skjødt, K, Stavenhagen, J B, Volbracht, C & Pedersen, J T 2018, ' Highly specific and selective anti-pS396-tau antibody C10.2 targets seeding-competent tau ', Alzheimer's & Dementia: Translational Research & Clinical Interventions, vol. 4, pp. 521-534 . https://doi.org/10.1016/j.trci.2018.09.005مصطلحات موضوعية: 0301 basic medicine, Monoclonal antibody, medicine.drug_class, Tau protein, Hyperphosphorylation, Anti-tau antibodies, C10.2, Peptide, D1.2, 03 medical and health sciences, 0302 clinical medicine, C8.3, Tau seeding, mental disorders, medicine, IC50, chemistry.chemical_classification, biology, HEK 293 cells, Neurodegeneration, Featured Article, medicine.disease, Phospho-serine 396, C5.2, Cell biology, Psychiatry and Mental health, 030104 developmental biology, chemistry, biology.protein, Neurology (clinical), Antibody, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Florence Sotty, Lassina Badolo, Michael Aagaard Andersen, Garrick Paul Smith, Kenneth Vielsted Christensen, Poul Henning Jensen, Ross Jeggo
المصدر: Andersen, M A, Sotty, F, Jensen, P H, Badolo, L, Jeggo, R, Smith, G P & Christensen, K V 2019, ' Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model : Findings and Implications ', eNeuro, vol. 6, no. 6 . https://doi.org/10.1523/ENEURO.0453-18.2019
eNeuroمصطلحات موضوعية: Time Factors, Parkinson's disease, Antiparkinson Agents, Rats, Sprague-Dawley, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/antagonists & inhibitors, alpha-Synuclein/genetics, Medicine, Neurotoxin, Parkinson Disease/drug therapy, Pyrimidines/pharmacology, Neurons, Dependovirus/genetics, Kinase, General Neuroscience, Parkinson Disease, 3.1, LRRK2, General Medicine, Dependovirus, New Research, Pathophysiology, Corpus Striatum/drug effects, Subthalamic nucleus, Pyrroles/pharmacology, alpha-Synuclein, Female, Morpholines/pharmacology, Tyrosine 3-Monooxygenase/metabolism, Tyrosine 3-Monooxygenase, Morpholines, Motor Activity/drug effects, Genetic Vectors, Neuropathology, Motor Activity, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, α-synuclein, Subthalamic Nucleus, Animals, Humans, Pyrroles, Subthalamic Nucleus/drug effects, Kinase activity, Protein Kinase Inhibitors, PFE-360, AAV-α-synuclein, business.industry, Antiparkinson Agents/pharmacology, medicine.disease, Neurons/drug effects, Corpus Striatum, nervous system diseases, Disease Models, Animal, Pyrimidines, nervous system, Protein Kinase Inhibitors/pharmacology, Parkinson’s disease, Cancer research, Disorders of the Nervous System, Motor Deficit, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18e4a80ba326be9ee3a2715a50d4fb0
https://doi.org/10.1523/eneuro.0453-18.2019 -
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المؤلفون: Ross Jeggo, Michael Aagaard Andersen, Florence Sotty, Annemette V. Thougaard, Poul Henning Jensen, Garrick Paul Smith, Steen Larsen, Karen Malene Wegener, Lassina Badolo, Kenneth Vielsted Christensen
المصدر: Andersen, M A, Wegener, K M, Larsen, S, Badolo, L, Smith, G P, Jeggo, R, Jensen, P H, Sotty, F, Christensen, K V & Thougaard, A 2018, ' PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats ', Toxicology, vol. 395, pp. 15-22 . https://doi.org/10.1016/j.tox.2018.01.003
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Lung/anatomy & histology, Morpholines, Renal function, Kidney, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Toxicology, Kidney Function Tests, Kidney Tubules, Proximal, Pathogenesis, Rats, Sprague-Dawley, 03 medical and health sciences, Internal medicine, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/antagonists & inhibitors, medicine, Kidney/anatomy & histology, Animals, Pyrroles, Body Weight/drug effects, Enzyme Inhibitors, Lung, Hyaline, Kidney Tubules, Proximal/anatomy & histology, Kinase, business.industry, urogenital system, Body Weight, Enzyme Inhibitors/toxicity, Morpholines/toxicity, LRRK2, Phenotype, nervous system diseases, Rats, Pyrimidines, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Pyrroles/toxicity, Female, business, Pyrimidines/toxicity
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4b70bb96ae7fd6091ca74006c2e9ba
https://pure.au.dk/portal/da/publications/pfe360induced-lrrk2-inhibition-induces-reversible-nonadverse-renal-changes-in-rats(f666ec43-387f-4304-8d83-ae9cad24b2ec).html