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المؤلفون: Edwige Lorthiois, Marc Gerspacher, Kim S. Beyer, Andrea Vaupel, Catherine Leblanc, Rowan Stringer, Andreas Weiss, Rainer Wilcken, Daniel A. Guthy, Andreas Lingel, Claudio Bomio-Confaglia, Rainer Machauer, Pascal Rigollier, Johannes Ottl, Dorothee Arz, Pascal Bernet, Gaëlle Desjonqueres, Solene Dussauge, Malika Kazic-Legueux, Marie-Anne Lozac’h, Christophe Mura, Mickaël Sorge, Milen Todorov, Nicolas Warin, Florence Zink, Hans Voshol, Frederic J. Zecri, Richard C. Sedrani, Nils Ostermann, Saskia M. Brachmann, Simona Cotesta
المصدر: Journal of Medicinal Chemistry. 65:16173-16203
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Claudia Betschart, Michael Faller, Florence Zink, René Hemmig, Jutta Blank, Eric Vangrevelinghe, Marjorie Bourrel, Ralf Glatthar, Dirk Behnke, Kerstin Barker, Andreas Heizmann, Daniela Angst, Pierre Nimsgern, Sébastien Jacquier, Tobias Junt, Géraldine Zipfel, Giulia Ruzzante, Pius Loetscher, Sarah Limonta, Stuart Hawtin, Cedric Bernard Andre, Thomas Boulay, Roland Feifel, Thomas Knoepfel
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry
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3
المؤلفون: Edwige, Lorthiois, Marc, Gerspacher, Kim S, Beyer, Andrea, Vaupel, Catherine, Leblanc, Rowan, Stringer, Andreas, Weiss, Rainer, Wilcken, Daniel A, Guthy, Andreas, Lingel, Claudio, Bomio-Confaglia, Rainer, Machauer, Pascal, Rigollier, Johannes, Ottl, Dorothee, Arz, Pascal, Bernet, Gaëlle, Desjonqueres, Solene, Dussauge, Malika, Kazic-Legueux, Marie-Anne, Lozac'h, Christophe, Mura, Mickaël, Sorge, Milen, Todorov, Nicolas, Warin, Florence, Zink, Hans, Voshol, Frederic J, Zecri, Richard C, Sedrani, Nils, Ostermann, Saskia M, Brachmann, Simona, Cotesta
المصدر: Journal of medicinal chemistry.
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4
المؤلفون: Mark Freeman, Victoria Head, Binesh Shrestha, Michael Faller, Elizabeth Hardaker, Mark R Dowling, Rene Hemmig, Lucy Elphick, Johan C. Hill, Darren Le Grand, David D. Pascoe, Florence Zink, Christopher Thomson, Andrew Lister, S. Rieffel, David Beattie, Oliver Ross Steward
المصدر: Bioorganicmedicinal chemistry letters. 31
مصطلحات موضوعية: Models, Molecular, Clinical Biochemistry, hERG, Pharmaceutical Science, Tetrazoles, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Drug Development, In vivo, Drug Discovery, Animals, Humans, Tetrazole, Enzyme Inhibitors, Molecular Biology, PK/PD models, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Phosphoric Diester Hydrolases, Organic Chemistry, Combinatorial chemistry, Amides, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, chemistry, Cinnamates, Lipophilicity, biology.protein, Microsome, Molecular Medicine, Autotaxin, Selectivity
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المؤلفون: Gabi Schutzius, Michael Faller, Aimee Reynolds, Ralph Tiedt, Julia Klopp, Florian Fuchs, Laure C. Bouchez, Federico Tortelli, Nelly Leroy, Jonathan J. Turner, Guglielmo Roma, Simona Cotesta, Armin Beyerbach, Peter Drueckes, Shola M Richards, Debora Bonenfant, Heinrich Rueeger, Heinz Ruffner, Jutta Blank, Rémi Terranova, Peter Tarsa, Frederic Grandjean, Florian Nigsch, Sebastian Bergling, Natalie Dales, Alexandra Aebi, Paul W. Manley, Markus Schirle, Christian Kolter, Tewis Bouwmeester, Rene Hemmig, Sukhdeep Sahambi, Lori L. Jennings, Walter Carbone, Felix Lohmann, Alfred Zimmerlin, Jun Li, Susan Kirkland, Steffen Renner, Mathias Frederiksen, Vickie Driver, Amy Berwick, Florence Zink, Jason R. Thomas, Andrea Vaupel, Chris Dimitri, Vito Guagnano, Viktoria Gruber, Malvina Louis, Caroline Gubser Keller, Adrian Salathe
المصدر: Nature chemical biology. 17(3)
مصطلحات موضوعية: Keratinocytes, Male, Protein family, Transcription, Genetic, Phenotypic screening, Primary Cell Culture, Cell Cycle Proteins, Wounds, Nonpenetrating, Small Molecule Libraries, 03 medical and health sciences, Mice, Structure-Activity Relationship, Re-Epithelialization, In vivo, Skin Ulcer, medicine, Fluorescence Resonance Energy Transfer, Animals, Humans, Protein Isoforms, Protein Precursors, Molecular Biology, 030304 developmental biology, 0303 health sciences, integumentary system, Epidermis (botany), business.industry, 030302 biochemistry & molecular biology, Cell Biology, In vitro, Bromodomain, High-Throughput Screening Assays, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, Gene Expression Regulation, Cancer research, Epidermis, Keratinocyte, business, Ex vivo, Transcription Factors